Increased production of IL-1α and TNF-α in lipopolysaccharide-stimulated blood from obese patients with non-alcoholic fatty liver disease

Cytokine

Volumn 33, Issue 5, 2006, Pages 252-257

  Poniachik, Jaime ^a   Csendes, Attila ^a   Díaz, Juan C ^a   Rojas, Jorge ^a   Burdiles, Patricio ^a   Maluenda, Fernando ^a   Smok, Gladys ^a   Rodrigo, Ramón ^b   Videla, Luis A ^b  

^a HOSPITAL CLÍNICO UNIVERSIDAD DE CHILE   (Chile)

^b UNIVERSITY OF CHILE   (Chile)

Author keywords

Liver steatosis; Non alcoholic fatty liver disease; Obesity; Pro inflammatory cytokines; Steatohepatitis

Indexed keywords

INTERLEUKIN 1ALPHA; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ANTIREFLUX OPERATION; ARTICLE; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GASTRECTOMY; GASTROJEJUNOSTOMY; HOMEOSTASIS; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOPATHOGENESIS; IMMUNOSTIMULATION; IN VITRO STUDY; LIVER BIOPSY; MALE; MEASUREMENT; NONALCOHOLIC FATTY LIVER; OBESITY; PATHOPHYSIOLOGY; PATIENT; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; ROUX Y ANASTOMOSIS; UPREGULATION;

ADULT; AGED; CYTOKINES; FATTY LIVER; FEMALE; HUMANS; INFLAMMATION; INTERLEUKIN-1; LIPOPOLYSACCHARIDES; LIVER; MALE; MIDDLE AGED; OBESITY; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33646479192     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cyto.2006.02.006     Document Type: Article

References (32)

1. Angulo P. Nonalcoholic fatty liver disease. N Engl J Med 346 (2002) 1221-1231
2. Haque M., and Sanyal A.J. The metabolic abnormalities associated with non-alcoholic fatty liver disease. Best Pract Res Clin Gastroenterol 16 (2002) 709-731
3. Neuschwander-Tetri B.A., and Caldwell S. Nonalcoholic Steatohepatitis: summary of an AASLD single topic conference. Hepatology 37 (2003) 1202-1219
4. Saltiel A.R., and Kahn C.R. Insulin signaling and the regulation of glucose and lipid metabolism. Nature 414 (2001) 799-806
5. Araya J., Rodrigo R., Videla L.A., Thielemann L., Orellana M., Pettinelli P., et al. Increase in long-chain polyunsaturated fatty acid n-6/n-3 ratio in relation to hepatic steatosis in patients with non-alcoholic fatty liver disease. Clin Sci (London) 106 (2004) 635-643
6. Clarke S.D. Nonalcoholic steatosis and steatohepatitis. I. Molecular mechanism for polyunsaturated fatty acid regulation of gene transcription. Am J Physiol Gastrointest Liver Physiol 281 (2001) G865-G869
7. Videla L.A., Rodrigo R., Araya J., and Poniachik J. Oxidative stress and depletion of hepatic long-chain polyunsaturated fatty acids may contribute to nonalcoholic fatty liver disease. Free Radic Biol Med 37 (2004) 1499-1507
8. Robertson G.R., Leclercq I., and Farrell G.C. Nonalcoholic steatosis and steatohepatitis: cytochrome P-450 enzymes and oxidative stress. Am J Physiol Gastrointest Liver Physiol 281 (2001) G1135-G1139
9. Videla L.A., Rodrigo R., Orellana M., Fernández V., Tapia G., Quiñones L., et al. Oxidative stress-related parameters in the liver of non-alcoholic fatty liver disease patients. Clin Sci (London) 106 (2004) 261-268
10. Tsukamoto H. Redox regulation of cytokine expression in Kupffer cells. Antioxid Redox Signal 4 (2002) 741-748
11. Poli G., Leonarduzzi G., Biasi F., and Chiarpoto E. Oxidative stress and cell signalling. Curr Med Chem 11 (2004) 1163-1182
12. De Groote D., Zangerle P.F., Gevaert Y., Fassote M.F., Beguin Y., Noizat-Pirenne F., et al. Direct stimulation of cytokines (IL-1β, TNF-α, IL-6, IL-2, IFM-γ and GM-CSF) in whole blood. I. Comparison with isolated PBMC stimulation. Cytokine 4 (1992) 239-248
13. Mayringer I., Reindl M., and Berger T. A critical comparison of frequently used methods for the analysis of tumor necrosis factor-α expression by human immune cells. J Immunol Methods 235 (2000) 33-40
14. Matthews D.R., Hosker J.P., Rudenski A.S., Naylor B.A., Treacher D.F., and Turner R.C. Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentration in man. Diabetologia 28 (1985) 412-419
15. Bacon R.B., Farahvash M.J., Janney C.G., and Neuschwander-Tetr B.A. Non-alcoholic steatohepatitis: an expanded clinical entity. Gastroenterology 107 (1994) 1103-1109
16. Das K., and Kar P. Non-alcoholic steatohepatitis. J Assoc Physicians India 53 (2005) 195-199
17. Winwood P.J., and Arthur M.J.P. Kupffer cells: their activation and role in animal models of liver injury and human liver disease. Semin Liver Dis 13 (1993) 50-59
18. Tilg H., and Diehl A.M. Cytokines in alcoholic and nonalcoholic steatohepatitis. N Engl J Med 343 (2000) 1467-1476
19. Forman H.J., and Torres M. Reactive oxygen species and cell signaling. Respiratory burst in macrophage signaling. Am J Crit Care Med 166 (2002) S4-S8
20. Garg A.K., and Aggarwal B.B. Reactive oxygen intermediates in TNF signaling. Mol Immunol 39 (2002) 509-517
21. Hotamisligil G.S., Peraldi S.P., Budavari A., Ellis R., White M.F., and Spiegelman B.M. IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance. Science 271 (1996) 665-668
22. Ramesh S., and Sanyal A.J. Evaluation and management of non-alcoholic steatohepatitis. J Hepatol 42 (2005) S2-S12
23. Wigg A.J., Roberts-Thomson I.C., Dymock R.B., McCarthy P.J., Grose R.H., and Cummins A.G. The role of small intestinal bacterial overgrowth, intestinal permeability, endotoxemia, and tumour necrosis factor α in the pathogenesis of non-alcoholic steatohepatitis. Gut 48 (2001) 206-211
24. Hui J.M., Hodge A., Farrell G.C., Kench J.G., Kriketos A., and George J. Beyond insulin resistance in NASH: TNF-α or adiponectin?. Hepatology 40 (2004) 46-54
25. Kugelmas M., Hill D.B., Vivian B., Marsano L., and McClain Cytokines C.J. NASH: a pilot study of the effects of lifestyle modification and vitamin E. Hepatology 38 (2003) 413-419
26. Crespo J., Cayon A., Fernandez-Gil P., Hernández-Guerra M., Mayorga M., Domínguez-Diez A., et al. Gene expression of tumor necrosis factor α and TNF-receptors p55 and p75, in nonalcoholic steatohepatitis patients. Hepatology 34 (2001) 1158-1163
27. Matsubara M. Plasma adiponectin decrease in women with nonalcoholic fatty liver. Endocr J 51 (2004) 587-593
28. Kaser S., Moschen A., Cayon A., Kaser A., Crespo J., Pons-Romero F., et al. Adiponectin and its receptors in non-alcoholic steatohepatitis. Gut 54 (2005) 117-121
29. Czaja M. Liver injury in the setting of steatosis: crosstalk between adipokine and cytokine. Hepatology 40 (2004) 19-22
30. Lafontan M. Fat cells: afferent and efferent messages define new approaches to treat obesity. Annu Rev Pharmacol Toxicol 45 (2005) 119-146
31. Weyer C., Funahashi T., Tanaka S., Horta K., Matsuzawa Y., Pratley R.E., et al. Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia. J Clin Endocrinol Met 86 (2001) 1930-1935
32. Gawrieh S., Opara E.C., and Koch T.R. Oxidative stress in nonalcoholic fatty liver disease: pathogenesis and antioxidant therapies. J Invest Med 52 (2004) 506-514