Nutritional genomics: Food industry applications from farm to fork

British Journal of Nutrition

Volumn 97, Issue 6, 2007, Pages 1027-1035

  Brown, Louise ^a   van der Ouderaa, Frans ^a  

^a UNILEVER RESEARCH   (United Kingdom)

Author keywords

Functional food; Gene diet interactions; Nutrigenetics; Nutrigenomics; Personalised nutrition

Indexed keywords

AGRICULTURAL MANAGEMENT; ANIMAL HEALTH; ARTICLE; BIOSYNTHESIS; BIOTECHNOLOGY; BREEDING; FARM ANIMAL; FOOD CHAIN; FOOD HANDLING; FOOD INDUSTRY; FOOD PROCESSING; FOOD QUALITY; FOOD SAFETY; FUNCTIONAL FOOD; FUNCTIONAL GENOMICS; GENETIC MARKER; HEALTH CARE MANAGEMENT; HIGH THROUGHPUT SCREENING; HUMAN; LIVESTOCK; METABOLOMICS; NONHUMAN; NUTRIGENOMICS; NUTRITIONAL HEALTH; NUTRITIONAL SCIENCE; PLANT BREEDING; PROTEOMICS; QUALITY CONTROL; TRANSCRIPTOMICS;

AGRICULTURE; FOOD HANDLING; FOOD INDUSTRY; FOOD TECHNOLOGY; FOOD, FORTIFIED; GENOMICS; HUMANS; NUTRITION PHYSIOLOGY;

ANIMALIA;

EID: 34250363501     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114507691983     Document Type: Article

References (71)

1. Abee T, van Schaik W & Siezen RJ (2004) Impact of genomics on microbial food safety. Trends Biotechnol 22, 653-660.
2. Battershill JM (2005) Toxicogenomics: Regulatory perspective on current position. Hum Experimental Toxicol 24, 35-40.
3. Bautista MC & Engler MM (2005) The Mediterranean diet: Is it cardioprotective? Prog Cardiovasc Nurs 20, 70-76.
4. Bonaa KH, Njolstad I, Ueland PM, Schirmer H, Tverdal A, Steigen T, Wang H, Nordrehaug JE, Arnesen E & Rasmussen K (2006) Homocysteine lowering and cardiovascular events after acute myocardial infarction. N Engl J Med 354, 1578-1588.
5. Bourre JM (2005) Where to find omega-3 fatty acids and how feeding animals with diet enriched in omega-3 fatty acids to increase nutritional value of derived products for human: What is actually useful? J Nutr Health Aging 9, 232-242.
6. Brindle JT, Antti K, Holmes E, et al. (2002) Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics. Nat Med 8, 1439-1444.
7. Brindle JT, Nicholson JK, Schofield PM, Grainger DJ & Holmes E (2003) Application of chemometrics to H-1 NMR spectroscopic data to investigate a relationship between human serum metabolic profiles and hypertension. Analyst 128, 32-36.
8. Buchanan-Wollaston V, Earl S, Harrison E, Mathas E, Nayabpour S, Page T & Pink D (2003) The molecular analysis of leaf senescence - a genomics approach. Plant Biotechnol J 1, 3-22.
9. Chadwick R (2004) Nutrigenomics, individualism and public health. Pro Nutr Soc 63, 161-166.
10. Chen LFO, Hwang JY, Charng YY, Sun CW & Yang SF (2001) Transformation of broccoli (Brassica oleracea var. italica) with isopentenyltranferase gene via Agrobacterium tumefaciens for post-harvest yellowing retardation. Mol Breeding 7, 243-257.
11. Clarke R (2005) Homocysteine-lowering trials for prevention of heart disease and stroke. Sem Vasc Med 5, 215-222.
12. DellaPenna D (1999) Nutritional genomics: Manipulating plant micronutrients to improve human health. Science 285, 375-379.
13. Enattah NS, Sahi T, Savilahti E, Terwilliger JD, Peltonen L & Jarvela I (2002) Identification of a variant associated with adult-type hypolactasia. Nat Genet 30, 233-237.
14. Fisher ND & Hollenberg NK (2005) Flavanols for cardiovascular health: the science behind the sweetness. J Hypertens 23, 1453-1459.
15. Fuchs D, Winkelmann I, Johnson IT, Mariman E, Wenzel U & Daniel H (2005) Proteomics in nutrition research: Principles, technologies and applications. Br J Nutr 94, 302-314.
16. Gordon ES, Gordish Dressman HA & Hoffman EP (2005) The genetics of muscle atrophy and growth: The impact and implications of polymorphisms in animals and humans. Int J Biochem Cell Biol 37, 2064-2074.
17. Hails R & Kinderlerer J (2003) The GM public debate: Context and communication strategies. Nat Rev Genet 4, 819-825.
18. Harlizius B, van Wijk R & Merks JW (2004) Genomics for food safety and sustainable animal production. J Biotechnol 113, 33-42.
19. Heijne WH, Kienhuis AS, van Ommen B, Stierum RH & Groten JP (2005) Systems toxicology: Applications of toxicogenomics, transcriptomics, proteomics and metabolomics in toxicology. Expert Rev Proteomics 2, 767-780.
20. Hendriks HF, Weststrate JA, van Vliet T & Meijer GW (1999) Spreads enriched with three different levels of vegetable oil sterols and the degree of cholesterol lowering in normocholesterolaemic and mildly hypercholesterolaemic subjects. Eur J Clin Nutr 53, 319-327.
21. Renzi MX, Christey MC & McNeil DL (2000) Morphological characterisation and agronomic evaluation of transgenic broccoli (Brassica oleracea L. var. italica) containing an antisense ACC oxidase gene. Euphytica 113, 9-18.
22. Herman WH, Hoerger TJ, Brandle M, Hicks K, Sorensen S, Zhang P, Hamman RF, Ackermann RT, Engelgau MM & Ratner RE (2005) The cost-effectiveness of lifestyle modification or metformin in preventing type 2 diabetes in adults with impaired glucose tolerance. Ann Intern Med 142, 323-332.
23. Hillier LW, Miller W, Birney E, et al. (2004) Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution. Nature 432, 695-716.
24. Hogenauer C, Hammer HF, Mellitzer K, Renner W, Kzejs GJ & Toplak H (2005) Evaluation of a new DNA test compared with the lactose hydrogen breath test for the diagnosis of lactase nonpersistence. Eur J Gastroenterol Hepatol 17, 371-376.
25. Jain S, Jain RK & McCouch SR (2004) Genetic analysis of Indian aromatic and quality rice (Oryza sativa L.) germplasm using panels of fluorescently-labeled microsatellite markers. Theor Appl Genet 109, 965-977.
26. Jarvela IE (2005) Molecular genetics of adult-type hypolactasia. Ann Med 37, 179-185.
27. Jiang RS, Xu GY, Zhang XQ & Yang N (2005) Association of polymorphisms for prolactin and prolactin receptor genes with broody traits in chickens. Poult Sci 84, 839-845.
28. Kaput J, Ordovas JM, Ferguson L, et al. (2005) The case for strategic international alliances to harness nutritional genomics for public and personal health. Br J Nutr 94, 623-632.
29. Knowler WC, Barrett-Connor E, Fowler SE, Hamman RF, Lachin JM, Walker EA & Nathan DM (2002) Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 346, 393-403.
30. Lewis SJ, Ebrahim S & Smith GD (2005) Meta-analysis of MTHFR 677C → T polymorphism and coronary heart disease: Does totality of evidence support causal role for homocysteine and preventive potential of folate? Br Med J 331, 1053-1056A.
31. Li G, Hu Y, Yang W, Jiang Y, Wang J, Xiao J, Hu Z, Pan X, Howard BV & Bennett PH (2002) Effects of insulin resistance and insulin secretion on the efficacy of interventions to retard development of type 2 diabetes mellitus: The DA Qing IGT and Diabetes Study. Diabetes Res Clin Pract 58, 193-200.
32. Lindon JC, Keun HC, Ebbels TMD, Pearce JMT, Holmes E & Nicholson JK (2005) The Consortium for Metabonomic Toxicology (COMET): Aims, activities and achievements. Pharmacogenomics 6, 691-699.
33. Lock AL & Bauman DE (2004) Modifying milk fat composition of dairy cows to enhance fatty acids beneficial to human health. Lipids 39 1197-1206.
34. Lonn E, Yusuf S, Arnold MJ, et al. (2006) Homocysteine lowering with folic acid and B vitamins in vascular disease. N Engl J Med 354, 1567-1577.
35. McCabe MS, Garratt LC, Schepers F, Jordi WJRM, Stoopen GM, Davelaar E, van Rhijn JHA, Power JB & Davey MR (2001) Effects of P-SAG12-IPT gene expression on development and senescence in transgenic lettuce. Plant Physiology 127, 505-516.
36. McMahon JA, Green TJ, Skeaff CM, Knight RG, Mann JI & Williams SM (2006) A controlled trial of homocysteine lowering and cognitive performance. N Engl J Med 354, 2764-2772.
37. Matthews SB, Waud JP, Roberts AG & Campbell AK (2005) Systemic lactose intolerance: A new perspective on an old problem. Postgrad Med J 81, 167-173.
38. Miyaki K, Murata M, Kikuchi H, Takei I, Nakayama T, Watanabe K & Omae K (2005) Assessment of tailor-made prevention of atherosclerosis with folic acid supplementation: Randomized, double-blind, placebo-controlled trials in each MTHFR C677T genotype. J Hum Genet 50, 241-248.
39. Muir SR, Collins GJ, Robinson S, Hughes S, Bovy A, Ric DV, van Tunen AJ & Verhoeyen ME (2001) Overexpression of petunia chalcone isomerase in tomato results in fruit containing increased levels of flavonols. Nat Biotechnol 19, 470-474.
40. Nugent AP (2005) LIPGENE: An EU project to tackle the metabolic syndrome. Biochimie 87, 129-132.
41. Page T, Griffiths G & Buchanan-Wollaston V (2001) Molecular and biochemical characterization of postharvest senescence in broccoli. Plant Physiol 125, 718-727.
42. Paine JA, Shipton CA, Chaggar S, et al. (2005) Improving the nutritional value of Golden Rice through increased pro-vitamin A content. Nat Biotechnol 23, 482-487.
43. Pareek CS, Czarnik U, Zabolewicz T, Pareek RS & Walawski K (2005) DGAT1 K232A quantitative trait nucleotide polymorphism in Polish Black-and-White cattle. J Appl Genet 46, 85-87.
44. Rasinpera H, Savilahti E, Enattah NS, Kuokkanen M, Totterman N, Lindahl H, Jarvela I & Kolho KL (2004) A genetic test which can be used to diagnose adult-type hypolactasia in children. Gut 53, 1571-1576.
45. Reynolds VL (2005) Applications of emerging technologies in toxicology and safety assessment. Int J Toxicol 24, 135-137.
46. Roy R, Ordovas L, Zaragoza P, Romero A, Moreno C, Altarriba J & Rodellar C (2006) Association of polymorphisms in the bovine FASN gene with milk-fat content. Anima Genet 37, 215-218.
47. Saris WH & Harper A (2005) DiOGenes: A multidisciplinary offensive focused on the obesity epidemic. Obes Rev 6, 175-176.
48. Saw SM, Yuan JM, Ong CN, Arakawa K, Lee HP, Coetzee GA & Yu MC (2001) Genetic, dietary, and other lifestyle determinants of plasma homocysteine concentrations in middle-aged and older Chinese men and women in Singapore. Am J Clinic Nutr 73, 232-239.
49. Schaefer EJ, Lamon-Fava S, Ausman LM, Ordovas JM, Clevidence BA, Judd JT, Goldin BR, Woods M, Gorbach S & Lichtenstein AH (1997) Individual variability in lipoprotein cholesterol response to National Cholesterol Education Program Step 2 diets. Am J Clin Nutr 65, 823-830.
50. Seshadri S (2006) Elevated plasma homocysteine levels: Risk factor of risk marker for the development of dementia and Alzheimer's disease? J Alzheimers D 9, 393-398.
51. Sibley E (2004) Carbohydrate intolerance. Curr Opin Gastroenterol 20, 162-167.
52. Slade AJ & Knauf VC (2005) TILLING moves beyond functional genomics into crop improvement. Transgenic Res 14, 109-115.
53. Solanky KS, Bailey JC, Beckwith-Hall BM, Davis A, Bingham S, Holmes E, Nicholson JK & Cassidy A (2003) Application of biofluid 1H nuclear magnetic resonance-based metabonomic techniques for the analysis of the biochemical effects of dietary isoflavones on human plasma profiles. Anal Biochem 323, 197-204.
54. Solanky KS, Bailey NJ, Beckwith-Hall BM, Bingham S, Davis A, Holmes E, Nicholson JK, & Cassidy A (2005) Biofluid H-1 NMR-based metabonomic techniques in nutrition research metabolic effects of dietary isoflavones in humans. J Nutr Biochem 16, 236-244.
55. Steinhilber SH (2005) Influence of strain and age of hen and dietary fat on the incorporation of omega-3-fatty acids into chicken eggs and on egg quality parameters. Archiv fur Geflugelkunde 69, 94-95.
56. Stott DJ, MacIntosh G, Do Lowe G, et al. (2005) Randomized controlled trial of homocysteine-lowering vitamin treatment in elderly patients with vascular disease. Am J Clin Nutr 82, 1320-1326.
57. Strain JJ, Dowey L, Ward M, Pentieva K & McNulty H (2004) B-vitamins, homocysteine metabolism and CVD. Proc Nutr Soc 63, 597-603.
58. Taboada EN, Acedillo RR, Carrillo CD, Findlay WA, Medeiros DT, Mykytczuk OL, Roberts MJ, Valenciá CA, Farber JM & Nash JH (2004) Large-scale comparative genomics meta-analysis of Campylobacter jejuni isolates reveals low level of genome plasticity. J Clin Microbiol 42, 4566-4576.
59. Troen A & Rosenberg I (2006) Homocysteine and cognitive function. Sem Vasc Med 5, 209-214.
60. Tuomilehto J, Lindstrom J, Eriksson JG, et al. (2001) Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Engl J Med 344, 1343-1350.
61. Ulvik A, Ueland PM, Fredriksen A, Meyer K, Vollset SE, Hoff G & Schneede J (2006) Functional inferece of the methylenetetrahydrofolate reductase 677 C > T and 1298A > C polymorphisms from a large-scale epidemiological study. Hum Genet Published online: 18 Novemeber 2006.doi:10.1007/s00439-006-0290-2.
62. van der Werf MJ, Schuren FHJ, Bijlsma S, Tas AC & van Ommen B (2001) Nutrigenomics. Application of genomics technologies in nutritional sciences and food technology. J Food Sci 66, 772-780.
63. van Ommen B & Groten JP (2004) Nutrigenomics in efficacy and safety evaluation of food components. In Nutrigenetics and Nutrigenomics. World Rev Nutr Diet, vol. 93, pp. 134-152 [AP Simpopoulos and JM Ordovas, editors]. Basel: Karger.
64. Wang YL, Tang HR, Nicholson JK, Hylands PJ, Sampson, J & Holmes E (2005) A metabonomic strategy for the detection of the metabolic effects of chamomile (Matricaria recutita L.) ingestion. J Agri Food Chem 53, 191-196.
65. Weikard R, Kuhn C, Goldammer T, Freyer G & Schwerin M (2005) The bovine PPARGC1A gene: Molecular characterization and association of an SNP with variation of milk fat synthsis. Physiol Genomics 21, 1-13.
66. Whitfield PD, German AJ & Noble PJM (2004) Metabolomics: An emerging post-genomic tool for nutrition. Br J Nutr 92, 549-555.
67. Wild S, Roglic G, Green A, Sicree R & King H (2004) Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030. Diabetes Care 27, 1047-1053.
68. Williams R (2005) Gene tests served up to tell fine foods from fakes. Nature 434, 262.
69. Wong GK Liu B, Wang J, et al. (2004) A genetic variation map for chicken with 2.8 million single-nucleotide polymorphisms. Nature 432, 717-722.
70. Woolfe M & Primrose S (2004) Food forensics: Using DNA technology to combat misdescription and fraud. Trends Biotechnol 22, 222-226.
71. Ye X, Al Babili S, Kloti A, Zhang J, Lucca P, Beyer P & Potrykus I (2000) Engineering the provitamin A (beta-carotene) biosynthetic pathway into (carotenoid-free) rice endosperm. Science 287, 303-305.