Nutritional genomics: Manipulating plant micronutrients to improve human health

Science

Volumn 285, Issue 5426, 1999, Pages 375-379

  DellaPenna, Dean ^a  

^a UNIVERSITY OF NEVADA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; BIOTIN; CALCIUM; FOLIC ACID; IODINE; IRON; PYRIDOXINE; RETINOL; SELENIUM; TRACE ELEMENT;

AGRICULTURAL RESEARCH; NUTRITION; TRACE ELEMENT;

AGRICULTURE; BIOSYNTHESIS; BREEDING; CROP; DIETARY INTAKE; FOOD INDUSTRY; GENE SEQUENCE; HEALTH PROMOTION; HUMAN; MOLECULAR GENETICS; NUTRIENT; NUTRITION; PHYTOCHEMISTRY; PRIORITY JOURNAL; REVIEW;

COMPUTATIONAL BIOLOGY; CROPS, AGRICULTURAL; CROSSES, GENETIC; DIET; GENOME, PLANT; HEALTH PROMOTION; HUMANS; MICRONUTRIENTS; NUTRITION PHYSIOLOGY; NUTRITIVE VALUE; PLANTS, EDIBLE; SEQUENCE ANALYSIS, DNA;

ANIMALIA;

EID: 0033575371     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.285.5426.375     Document Type: Review

References (53)

1. D. H. Calloway, Human Nutrition: Food and Micronutrient Relationships (International Food Policy Research Institute, Washington, DC, 1395).
2. B. A. Underwood, Nutr. Today 33, 121 (1998).
3. W. Mertz, Nutr. Rev. 55, 44 (1997).
4. A. E. Harper, Annu. Rev. Nutr. 7, 509 (1987).
5. J. E. Buring and C. H. Hennekens, Nutr. Rev. 55, S53 (1997).
6. J. P. Kehrer and C. V. Smith, Free Radicals in Biology: Sources, Reactivities, and Roles in the Etiology of Human Diseases, B. Frei, Ed., Natural Antioxidants in Human Health and Diseases (Academic Press, San Diego, CA, 1994), vol. 2; K. A. Steinmetz and J. D. Potter, J. Am. Diet. Assoc. 96, 1027 (1996).
7. J. P. Kehrer and C. V. Smith, Free Radicals in Biology: Sources, Reactivities, and Roles in the Etiology of Human Diseases, B. Frei, Ed., Natural Antioxidants in Human Health and Diseases (Academic Press, San Diego, CA, 1994), vol. 2; K. A. Steinmetz and J. D. Potter, J. Am. Diet. Assoc. 96, 1027 (1996).
8. AIFCR World Cancer Research Fund, Food, Nutrition and the Prevention of Cancer a Global Perspective (American Institute for Cancer Research, Washington, DC, 1997).
9. J. B. Harborne, Introduction to Ecological Biochemistry (Academic Press, San Diego, CA, ed. 4, 1993); E. Conn, in Phytochemicals and Health, D. L. Gustine and H. L. Flores, Eds. (American Society of Plant Physiologists, Rockville, MD, 1995), pp. 1-14.
10. J. B. Harborne, Introduction to Ecological Biochemistry (Academic Press, San Diego, CA, ed. 4, 1993); E. Conn, in Phytochemicals and Health, D. L. Gustine and H. L. Flores, Eds. (American Society of Plant Physiologists, Rockville, MD, 1995), pp. 1-14.
11. G. Block, B. Patterson, A. Subar, Nutr. Cancer 18, 1 (1992).
12. P. A. Lachance, Nutr. Rev. 56, S34 (1998).
13. S. S. Hecht, J. Cell Biochem. Suppl. 22, 195 (1995).
14. P. Talalay and Y. Zhang, Biochem. Soc. Trans. 24, 806 (1996).
15. Reviewed in M. S. Kurzer and X. Xu, Annu. Rev. Nutr. 17, 353 (1997).
16. J.-L. Charteux, Nutr. Rev. 54, S109 (1996).
17. I. Schonhof and A. Krumbein, Gartenbauwissenschaft 61, 281 (1996).
18. M. Wang and I. L. Goldman, J. Am. Soc. Hortic. Sci. 121, 1040 (1996).
19. M. A. Grusak, B. W. Stephens, D. J. Merhaut, ibid., p. 656; J. R. Stommel, J. Hered. 85, 401 (1994); P. W. Simon, X. Y. Wolff, C. E. Peterson, D. S. Kammerlohr, Hortscience 24, 174 (1989).
20. M. A. Grusak, B. W. Stephens, D. J. Merhaut, ibid., p. 656; J. R. Stommel, J. Hered. 85, 401 (1994); P. W. Simon, X. Y. Wolff, C. E. Peterson, D. S. Kammerlohr, Hortscience 24, 174 (1989).
21. M. A. Grusak, B. W. Stephens, D. J. Merhaut, ibid., p. 656; J. R. Stommel, J. Hered. 85, 401 (1994); P. W. Simon, X. Y. Wolff, C. E. Peterson, D. S. Kammerlohr, Hortscience 24, 174 (1989).
22. B. Pogson, K. McDonald, M. Truong, G. Britton, D. DellaPenna, Plant Cell 8, 1627 (1996).
23. B. W. Shirley et al., Plant J. 8, 659 (1995).
24. S. R. Norris, T. R. Barrette, D. DellaPenna, Plant Cell 7, 2139 (1995).
25. P. L. Conklin, J. E. Pallanca, R. L. Last, N. Smirnoff, Plant Physiol. 115, 1277 (1997).
26. Reviewed in F. X. Cunningham and E. Gantt, Annu. Rev. Plant Physiol. Plant Mol. Biol. 49, 557 (1998).
27. S. R. Norris, X. Shen, D. DellaPenna, Plant Physiol. 117, 1317 (1998).
28. P. Baldet, C. Alban, R. Douce, FEBS Lett. 419, 206 (1997); F. C. Belanger, T. Leustek, B. Chu, A. L. Kriz, Plant Mol. Biol. 29, 809 (1995); D. Eide, M. Broderius, J. Fett, M. L. Guerinot, Proc. Natl. Acad. Sci. U.S.A. 93, 5624 (1996).
29. P. Baldet, C. Alban, R. Douce, FEBS Lett. 419, 206 (1997); F. C. Belanger, T. Leustek, B. Chu, A. L. Kriz, Plant Mol. Biol. 29, 809 (1995); D. Eide, M. Broderius, J. Fett, M. L. Guerinot, Proc. Natl. Acad. Sci. U.S.A. 93, 5624 (1996).
30. P. Baldet, C. Alban, R. Douce, FEBS Lett. 419, 206 (1997); F. C. Belanger, T. Leustek, B. Chu, A. L. Kriz, Plant Mol. Biol. 29, 809 (1995); D. Eide, M. Broderius, J. Fett, M. L. Guerinot, Proc. Natl. Acad. Sci. U.S.A. 93, 5624 (1996).
31. The C. elegans Sequencing Consortium, Science 282, 2012 (1998); F. Sterky et al., Proc. Natl. Acad. Sci. U.S.A. 95, 13330 (1998); K. Yamamoto and T. Sasaki, Plant Mol. Biol. 35, 135 (1997).
32. The C. elegans Sequencing Consortium, Science 282, 2012 (1998); F. Sterky et al., Proc. Natl. Acad. Sci. U.S.A. 95, 13330 (1998); K. Yamamoto and T. Sasaki, Plant Mol. Biol. 35, 135 (1997).
33. The C. elegans Sequencing Consortium, Science 282, 2012 (1998); F. Sterky et al., Proc. Natl. Acad. Sci. U.S.A. 95, 13330 (1998); K. Yamamoto and T. Sasaki, Plant Mol. Biol. 35, 135 (1997).
34. T. Desprez, J. Amselem, M. Caboche, H. Höfte, Plant J. 14, 643 (1998); Y. Ruan, J. Gilmore, T. Conner, ibid. 15, 821 (1998).
35. T. Desprez, J. Amselem, M. Caboche, H. Höfte, Plant J. 14, 643 (1998); Y. Ruan, J. Gilmore, T. Conner, ibid. 15, 821 (1998).
36. T. Kaneko et al., DNA Res. 3, 109 (1996).
37. D. Shintani and D. DellaPenna, Science 282, 2098 (1998).
38. J. L. DeRisi, V. R. Iyer, P. O. Brown, ibid. 278, 680 (1997); V. R. Iyer et al., ibid. 283, 83 (1999).
39. J. L. DeRisi, V. R. Iyer, P. O. Brown, ibid. 278, 680 (1997); V. R. Iyer et al., ibid. 283, 83 (1999).
40. E. E. Ziegler and L. J. J. Filer, Eds., Present Knowledge in Nutrition (International Life Sciences Institute, Washington, DC, 1996).
41. C. D. Arnaud and S. D. Sanchez, ibid., pp. 245-255.
42. J. J. Winzerling and L. H. Law, Annu. Rev. Nutr. 17, 501 (1997).
43. F. Delange, Thyroid 4, 107 (1994).
44. O. A. Levander and R. F. Burk, in (30), pp. 320-328.
45. H. E. Sauberlich, Annu. Rev. Nutr. 14, 371 (1994).
46. J. E. Leklem, in (30), pp. 174-183.
47. C. E. J. Butterworth and A. Bendich, Annu. Rev. Nutr. 16, 73 (1996).
48. D. M. Mock, in (30), pp. 220-235.
49. M. G. Traber and H. Sies, Annu. Rev. Nutr. 16, 321 (1996).
50. C. L. Rock, Pharmacol. Ther. 75, 185 (1997).
51. Food and Nutrition Board, National Research Council (U.S.), Recommended Dietary Allowances (National Academy Press, Washington, DC, ed. 10, 1989).
52. M. Jang et al., Science 275, 218 (1997).
53. I acknowledge all past and current laboratory members who contributed to work described in this article. Work described from my laboratory has been supported by the U.S. Department of Agriculture and Zeneca Plant Sciences.