Mapping of the vitronectin-binding site on the urokinase receptor involvement of a coherent receptor: Interface consisting of residues from both domain I and the flanking interdomain linker region

Journal of Biological Chemistry

Volumn 282, Issue 18, 2007, Pages 13561-13572

  Gårdsvoll, Henrik ^a   Ploug, Michael ^a  

^a FINSEN LABORATORY   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING SITES; CELL ADHESION; ENZYMES; TUMORS; X RAY CRYSTALLOGRAPHY;

CELL MOTILITY; SOMATOMEDIN B DOMAIN; VITRONECTIN;

GLYCOPROTEINS;

UROKINASE RECEPTOR; VITRONECTIN; CELL SURFACE RECEPTOR; EPITOPE; PLASMINOGEN ACTIVATOR, UROKINASE RECEPTORS; SOMATOMEDIN; SOMATOMEDIN B; UNCLASSIFIED DRUG;

AMES TEST; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BETA SHEET; BINDING SITE; COMPLEX FORMATION; CONTROLLED STUDY; DNA FLANKING REGION; FEMALE; GENE MAPPING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; ANIMAL; CELL ADHESION; CELL MOTION; CHEMISTRY; CHO CELL; CRICETULUS; EPITOPE MAPPING; GENETICS; HAMSTER; HUMAN; IMMUNOLOGY; METABOLISM; METASTASIS; MISSENSE MUTATION; NEOPLASM; PROTEIN BINDING; PROTEIN QUATERNARY STRUCTURE; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; SITE DIRECTED MUTAGENESIS;

AMINO ACID SUBSTITUTION; ANIMALS; CELL ADHESION; CELL MOVEMENT; CHO CELLS; CRICETINAE; CRICETULUS; EPITOPE MAPPING; EPITOPES; HUMANS; MUTAGENESIS, SITE-DIRECTED; MUTATION, MISSENSE; NEOPLASM METASTASIS; NEOPLASMS; PROTEIN BINDING; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CELL SURFACE; SOMATOMEDINS; VITRONECTIN;

EID: 34250318934     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M610184200     Document Type: Article

References (49)

1. Ploug, M., Rønne, E., Behrendt, N., Jensen, A. L., Blasi, F., and Danø, K. (1991) J. Biol. Chem. 266, 1926-1933
2. Ploug, M. (2003) Curr. Pharm. Des. 9, 1499-1528
3. Liu, S., Bugge, T. H., and Leppla, S. H. (2001). J. Biol. Chem. 276, 17976-17984
4. Ellis, V., Scully, M. F., and Kakkar, V. V. (1989) J. Biol. Chem. 264, 2185-2188
5. Bolon, I., Zhou, H. M., Charron, Y., Wohlwend, A., and Vassalli, J. D. (2004) Am. J. Pathol. 164, 2299-2304
6. Zhou, H. M., Nichols, A., Meda, P., and Vassalli, J. D. (2000) EMBO J. 19, 4817-4826
7. Liu, S., Aaronson, H., Mitola, D. J., Leppla, S. H., and Bugge, T. H. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 657-662
8. Gårdsvoll, H., Gilquin, B., Le Du, M. H., Ménez, A., Jørgensen, T. J., and Ploug, M. (2006) J. Biol. Chem. 281, 19260-19272
9. Ploug, M., Østergaard, S., Hansen, L. B., Holm, A., and Danø, K. (1998) Biochemistry 37, 3612-3622
10. Ploug, M., Ellis, V., and Danø, K. (1994) Biochemistry 33, 8991-8997
11. Gårdsvoll, H., Danø, K., and Ploug, M. (1999) J. Biol. Chem. 274, 37995-38003
12. Li, Y., Lawrence, D. A., and Zhang, L. (2003) J. Biol. Chem. 278, 29925-29932
13. Bdeir, K., Kuo, A., Mazar, A., Sachais, B. S., Xiao, W., Gawlak, S., Harris, S., Higazi, A. A., and Cines, D. B. (2000) J. Biol. Chem. 275, 28532-28538
14. Ploug, M. (1998) Biochemistry 37, 16494-16505
15. Ploug, M., Østergaard, S., Gårdsvoll, H., Kovalski, K., Holst-Hansen, C., Holm, A., Ossowski, L., and Danø, K. (2001) Biochemistry 40, 12157-12168
16. Jørgensen, T. J., Gårdsvoll, H., Danø, K., Roepstorff, P., and Ploug, M. (2004) Biochemistry 43, 15044-15057
17. Llinas, P., Le Du, M. H., Gårdsvoll, H., Danø, K., Ploug, M., Gilquin, B., Stura, E. A., and Ménez, A. (2005) EMBO J. 24, 1655-1663
18. Huai, Q., Mazar, A. P., Kuo, A., Parry, G. C., Shaw, D. E., Callahan, J., Li, Y., Yuan, C., Bian, C., Chen, L., Furie, B., Furie, B. C., Cines, D. B., and Huang, M. (2006) Science 311, 656-659
19. Barinka, C., Parry, G., Callahan, J., Shaw, D. E., Kuo, A., Bdeir, K., Cines, D. B., Mazar, A., and Lubkowski, J. (2006) J. Mol. Biol. 363, 482-495
20. Rømer, J., Nielsen, B. S., and Ploug, M. (2004) Curr. Pharm. Des. 10, 2359-2376
21. Waltz, D. A., and Chapman, H. A. (1994) J. Biol. Chem. 269, 14746-14750
22. Wei, Y., Waltz, D. A., Rao, N., Drummond, R. J., Rosenberg, S., and Chapman, H. A. (1994) J. Biol. Chem. 269, 32380-32388
23. Wei, Y., Lukashev, M., Simon, D. I., Bodary, S. C., Rosenberg, S., Doyle, M. V., and Chapman, H. A. (1996) Science 273, 1551-1555
24. Wei, Y., Czekay, R. P., Robillard, L., Kugler, M. C., Zhang, F., Kim, K. K., Xiong, J. P., Humphries, M. J., and Chapman, H. A. (2005) J. Cell Biol. 168, 501-511
25. Sidenius, N., Andolfo, A., Fesce, R., and Blasi, F. (2002) J. Biol. Chem. 277, 27982-27990
26. Pluskota, E., Soloviev, D. A., and Plow, E. F. (2003) Blood 101, 1582-1590
27. Sidenius, N., and Blasi, F. (2000) FEBS Lett. 470, 40-46
28. Cunningham, O., Andolfo, A., Santovito, M. L., Iuzzolino, L., Blasi, F., and Sidenius, N. (2003) EMBO J. 22, 5994-6003
29. Høyer-Hansen, G., Behrendt, N., Ploug, M., Danø, K., and Preissner, K. T. (1997) FEBS Lett. 420, 79-85
30. Rønne, E., Behrendt, N., Ellis, V., Ploug, M., Danø, K., and Høyer-Hansen, G. (1991) FEBS Lett. 288, 233-236
31. Gårdsvoll, H., Werner, F., Søndergaard, L., Danø, K., and Ploug, M. (2004) Protein Expression Purif. 34, 284-295
32. Barkholt, V., and Jensen, A. L. (1989) Anal. Biochem. 177, 318-322
33. Rønne, E., Behrendt, N., Ploug, M., Nielsen, H. J., Wöllisch, E., Weidle, U., Danø, K., and Høyer-Hansen, G. (1994) J. Immunol. Methods 167, 91-101
34. Gårdsvoll, H., Hansen, L. V., Jørgensen, T. J., and Ploug, M. (2007) Protein Expression Purif. 52, 384-394
35. Picard, V., Ersdal-Badju, E., Lu, A., and Bock, S. C. (1994) Nucleic Acids Res. 22, 2587-2591
36. Ploug, M., and Ellis, V. (1994) FEBS Lett. 349, 163-168
37. Deng, G., Royle, G., Wang, S., Crain, K., and Loskutoff, D. J. (1996) J. Biol. Chem. 271, 12716-12723
38. Deng, G., Curriden, S. A., Wang, S., Rosenberg, S., and Loskutoff, D. J. (1996) J. Cell Biol. 134, 1563-1571
39. Seger, D., Gechtman, Z., and Shaltiel, S. (1998) J. Biol. Chem. 273, 24805-24813
40. Kjøller, L., and Hall, A. (2001) J. Cell Biol. 152, 1145-1157
41. Resnati, M., Guttinger, M., Valcamonica, S., Sidenius, N., Blasi, F., and Fazioli, F. (1996) EMBO J. 15, 1572-1582
42. Fazioli, F., Resnati, M., Sidenius, N., Higashimoto, Y., Appella, E., and Blasi, F. (1997) EMBO J. 16, 7279-7286
43. Resnati, M., Pallavicini, I., Wang, J. M., Oppenheim, J., Serhan, C. N., Romano, M., and Blasi, F. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 1359-1364
44. Gargiulo, L., Longanesi-Cattani, I., Bifulco, K., Franco, P., Raiola, R., Campiglia, P., Grieco, P., Peluso, G., Stoppelli, M. P., and Carriero, M. V. (2005) J. Biol. Chem. 280, 25225-25232
45. Jacobsen, B., Gårdsvoll, H., Juhl Funch, G., Østergaard, S., Barkholt, V., and Ploug, M. (2007) Protein Expression Purif. 52, 286-296
46. Zhou, A., Huntington, J. A., Pannu, N. S., Carrell, R. W., and Read, R. J. (2003) Nat. Struct. Biol. 10, 541-544
47. Jensen, J. K., Wind, T., and Andreasen, P. A. (2002) FEBS Lett. 521, 91-94
48. Okumura, Y., Kamikubo, Y., Curriden, S. A., Wang, J., Kiwada, T., Futaki, S., Kitagawa, K., and Loskutoff, D. J. (2002) J. Biol. Chem. 277, 9395-9404
49. Moser, T. L., Enghild, J. J., Pizzo, S. V., and Stack, M. S. (1995) Biochem. J. 307, 867-873