The intact urokinase receptor is required for efficient vitronectin binding: Receptor cleavage prevents ligand interaction

FEBS Letters

Volumn 420, Issue 1, 1997, Pages 79-85

  Høyer Hansen, Gunilla ^a   Behrendt, Niels ^a   Ploug, Michael ^a   Danø, Keld ^a   Preissner, Klaus T ^b  

^a FINSEN LABORATORY   (Denmark)

^b KERCKHOFF HEART CENTER   (Germany)

Author keywords

Real time biomolecular interaction analysis; Receptor cleavage; Urokinase; Urokinase receptor; Vitronectin

Indexed keywords

CELL SURFACE RECEPTOR; PLASMINOGEN ACTIVATOR; RECEPTOR SUBTYPE; UROKINASE RECEPTOR; VITRONECTIN;

ARTICLE; BINDING SITE; CELL SURFACE; COMPLEX FORMATION; ELECTROPHORETIC MOBILITY; HUMAN; IMMUNOBLOTTING; KINETICS; LIGAND BINDING; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; REACTION ANALYSIS;

ANTIBODIES, MONOCLONAL; BINDING, COMPETITIVE; BIOSENSING TECHNIQUES; HUMANS; LIGANDS; NEURAMINIDASE; PLASMINOGEN ACTIVATOR INHIBITOR 1; RECEPTORS, CELL SURFACE; SOLUBILITY; URINARY PLASMINOGEN ACTIVATOR; VITRONECTIN;

EID: 0031583964     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(97)01491-9     Document Type: Article

References (35)

1. Danø K., Andreasen P.A., Grøndahl-Hansen J., Kristensen P., Nielsen L.S., Skriver L. Adv. Cancer Res. 44:1985;139-266.
2. Andreasen P.A., Kjøller L., Christensen L., Duffy M.J. Int. J. Cancer. 72:1997;1-22.
3. Behrendt N., Rønne E., Danø K. Biol. Chem. Hoppe-Seyler. 376:1995;269-279.
4. Ellis V., Wun T.C., Behrendt N., Rønne E., Danø K. J. Biol. Chem. 265:1990;9904-9908.
5. Behrendt N., Rønne E., Ploug M., Petri T., Løber D., Nielsen L.S., Schleuning W.-D., Blasi F., Appella E., Danø K. J. Biol. Chem. 265:1990;6453-6460.
6. Ploug M., Rønne E., Behrendt N., Jensen A.L., Blasi F., Danø K. J. Biol. Chem. 266:1991;1926-1933.
7. Behrendt N., Ploug M., Patthy L., Houen G., Blasi F., Danø K. J. Biol. Chem. 266:1991;7842-7847.
8. Ploug M., Kjalke M., Rønne E., Weidle U., Høyer-Hansen G., Danø K. J. Biol. Chem. 268:1993;17539-17546.
9. Ploug M., Ellis V., Danø K. Biochemistry. 33:1994;8991-8997.
10. Behrendt N., Rønne E., Danø K. J. Biol. Chem. 271:1996;22885-22894.
11. Høyer-Hansen G., Rønne E., Solberg H., Behrendt N., Ploug M., Lund L.R., Ellis V., Danø K. J. Biol. Chem. 267:1992;18224-18229.
12. Høyer-Hansen G., Ploug M., Behrendt N., Rønne E., Danø K. Eur. J. Biochem. 243:1997;21-26.
13. Wei Y., Waltz D.A., Rao N., Drummond J., Rosenberg S., Chapman H.A. J. Biol. Chem. 269:1994;32380-32388.
14. Kanse S.M., Kost C., Wilhelm O.G., Andreasen P.A., Preissner K.T. Exp. Cell Res. 244:1996;344-353.
15. Wei Y., Lukashev M., Simon D.I., Bodary S.C., Rosenberg S., Doyle M.V., Chapman H.A. Science. 273:1996;1551-1555.
16. Deng G., Curriden S.A., Wang S., Rosenberg S., Loskutoff D.J. J. Cell Biol. 134:1996;1-9.
17. Waltz D.A., Natkin L.R., Fujita R.M., Wei Y., Chapman H.A. J. Clin. Invest. 100:1997;58-67.
18. Preissner K.T., Wassmuth R., Müller-Berghaus G. Biochem. J. 231:1985;349-355.
19. Stockmann A., Hess S., Declerck P., Timpl R., Preissner K.T. J. Biol. Chem. 268:1993;22874-22882.
20. Rønne E., Behrendt N., Ploug M., Nielsen H.J., Wöllisch E., Weidle U., Danø K., Høyer-Hansen G. J. Immunol. Methods. 167:1994;91-101.
21. Behrendt N., Ploug M., Rønne E., Høyer-Hansen G., Danø K. Methods Enzymol. 223:1993;207-222.
22. Guesdon J.-L., Ternunck T., Avrameas S. J. Histochem. Cytochem. 27:1979;1131-1139.
23. Rønne E., Behrendt N., Ellis V., Ploug M., Danø K., Høyer-Hansen G. FEBS Lett. 288:1991;233-236.
24. Rønne E., Høyer-Hansen G., Brünner N., Pedersen H., Rank F., Osborne C.K., Clark G.M., Danø K., Grøndahl-Hansen J. Breast Cancer Res. Treat. 33:1995;199-207.
25. Laemmli V.K. Nature. 227:1970;680-685.
26. Solberg H., Løber D., Eriksen J., Ploug M., Rønne E., Behrendt N., Danø K., Høyer-Hansen G. Eur. J. Biochem. 2:1992;451-458.
27. BIAevaluation 2.1 Software Handbook (1995) Pharmacia Biosensor, Uppsala, Sweden.
28. Seiffert D., Loskutoff D.J. J. Biol. Chem. 266:1991;2824-2830.
29. Kost C., Stuber W., Ehrlich H.J., Pannekoek H., Preissner K.T. J. Biol. Chem. 267:1992;12098-12105.
30. Karlsson R., Michaelsson A., Mattsson L. J. Immunol. Methods. 145:1991;229-240.
31. Pellequer J.L., van Regenmortel M.H.V. J. Immunol. Methods. 166:1993;133-143.
32. Chain D., Kreizman T., Shapira H., Shaltiel S. FEBS Lett. 285:1991;251-256.
33. Høyer-Hansen, G., Solberg, H., Rønne, E., Behrendt, N. and Danø, K. (1993) in: Biology of Vitronectin and Their Receptors (Preissner, K.T., Rosenblatt, S., Kost, C., Wegerhoff, J. and Mosher, D., Eds.), pp. 289-294, Elsevier Science Publishers B.V., Amsterdam.
34. Mazzieri R., Høyer-Hansen G., Rønne E., Løber D., Vagnarelli P., Raimondi E., De Carli L., Danø K., Mignatti P. Fibrinolysis. 8:1994;344-352.
35. Solberg H., Rømer J., Brünner N., Holm A., Sidenius N., Danø K., Høyer-Hansen G. Int. J. Cancer. 58:1994;877-881.