Identification and biochemical studies on novel non-nucleoside inhibitors of the enzyme adenosine kinase

Protein Journal

Volumn 26, Issue 3, 2007, Pages 203-212

  Park, Jae ^a   Vaidyanathan, Gayathri ^a   Singh, Bhag ^a   Gupta, Radhey S ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

Adenosine; Adenosine kinase; Adenosine kinase inhibitors; Drug screening; Kinetics studies; Structure activity studies

Indexed keywords

2 [2 (3,4 DIHYDROXYPHENYL) 5 PHENYL 1H IMIDAZOL 4 YL]FLUOREN 9 ONE; 2 [3 (1H BENZOIMIDAZOL 2 YL) 6 METHOXYCHROMEN 2 YLIDENEAMINO] 4,5,6,7 TETRAHYDROBENZO[B]THIOPHENE 3 CARBOXYLIC ACID AMIDE; 2 TERT BUTYL 4H BENZO[1,2,4]THIADIAZINE 3 THIONE; 3 [3 (4 HYDROXYPHENYL) 4 OXO 2 THIOXOTHIAZOLIDIN 5 YLIDENE] 1 METHYL 1,3,3A,7A TETRAHYDROINDOL 2 ONE; 3 [5,6 BIS(4 METHOXYPHENYL)FURO[2,3 D]PYRIMIDIN 4 YLAMINO]PROPAN 1 OL; ADENOSINE KINASE INHIBITOR; CYCLOHEXYL (2 THIOPHEN 2 YLIMIDAZO[1,2 A]PYRAZIN 3 YL)AMINE; CYCLOPENTYL (2 THIOPHEN 2 YLIMIDAZO[1,2 A]PYRAZIN 3 YL)AMINE; N (5,6 DIPHENYLFURO[2,3 D]PYRIMIDIN 4 YL)PROPIONAMIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG IDENTIFICATION; DRUG PENETRATION; ENZYME INHIBITION; FEMALE; MAMMAL CELL; MOLECULAR WEIGHT; NONHUMAN;

ADENOSINE; ADENOSINE KINASE; ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; ENZYME INHIBITORS; HUMANS; KINETICS; PYRIMIDINES; RECOMBINANT PROTEINS; THIADIAZINES;

MAMMALIA;

EID: 34250217784     PISSN: 15723887     EISSN: 15734943     Source Type: Journal    
DOI: 10.1007/s10930-006-9062-z     Document Type: Article

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