Loss of insulin-mediated vasoprotection: Early effect of diabetes on pericyte-containing microvessels of the retina

Investigative Ophthalmology and Visual Science

Volumn 48, Issue 5, 2007, Pages 2350-2355

  Kobayashi, Takatoshi ^a   Puro, Donald G ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; DYE; GLUCOSE; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE; OXYGEN; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; STREPTOZOCIN; TRYPAN BLUE; ENZYME INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CELL PROTECTION; CELL STRUCTURE; CELL SURVIVAL; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC RETINOPATHY; DOSE RESPONSE; HYPOTHESIS; IC 50; IMMUNOREACTIVITY; INSULIN DEFICIENCY; MICROVASCULATURE; NONHUMAN; PERICYTE; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT; RETINA; RETINA BLOOD VESSEL; RETINA ISCHEMIA; STREPTOZOCIN DIABETES; ANIMAL; CAPILLARY; DRUG ANTAGONISM; EXPERIMENTAL DIABETES MELLITUS; ISCHEMIA; LONG EVANS RAT; METABOLISM; PATHOLOGY; PHYSIOLOGY;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; APOPTOSIS; CAPILLARIES; CASPASE 3; CELL SURVIVAL; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC RETINOPATHY; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; INSULIN; ISCHEMIA; PERICYTES; RATS; RATS, LONG-EVANS; RETINAL VESSELS;

EID: 34250214922     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.06-1357     Document Type: Article

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