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Volumn 109, Issue 12, 2007, Pages 5380-5389

Naturally occurring C-terminally truncated STAT5 is a negative regulator of HIV-1 expression

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CD8 ANTIGEN; GAG PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; RNA POLYMERASE II; SMALL INTERFERING RNA; STAT5 PROTEIN; TRANSCRIPTION FACTOR AP 1;

EID: 34250023195     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2006-08-042556     Document Type: Article
Times cited : (31)

References (79)
  • 1
    • 0038639554 scopus 로고    scopus 로고
    • 20 years of science
    • and AIDS
    • Fauci AS. HIV and AIDS: 20 years of science. Nat Med. 2003;9:839-843.
    • (2003) Nat Med , vol.9 , pp. 839-843
    • Fauci, A.H.1
  • 2
    • 0038299654 scopus 로고    scopus 로고
    • HIV-1 pathogenesis
    • Stevenson M. HIV-1 pathogenesis. Nat Med. 2003;9:853-860.
    • (2003) Nat Med , vol.9 , pp. 853-860
    • Stevenson, M.1
  • 3
    • 0032805660 scopus 로고    scopus 로고
    • Constitutive activation of STATs upon in vivo human immunodeficiency virus infection
    • Bovolenta C, Camorali L, Lorini AL, et al. Constitutive activation of STATs upon in vivo human immunodeficiency virus infection. Blood. 1999;94: 4202-4209.
    • (1999) Blood , vol.94 , pp. 4202-4209
    • Bovolenta, C.1    Camorali, L.2    Lorini, A.L.3
  • 4
    • 9644295710 scopus 로고    scopus 로고
    • Kovanen PE, Leonard WJ. Cytokines and immunodeficiency diseases: critical roles of the gamma(c)-dependent cytokines interleukins 2, 4, 7, 9, 15, and 21, and their signaling pathways. Immunol Rev. 2004;202:67-83.
    • Kovanen PE, Leonard WJ. Cytokines and immunodeficiency diseases: critical roles of the gamma(c)-dependent cytokines interleukins 2, 4, 7, 9, 15, and 21, and their signaling pathways. Immunol Rev. 2004;202:67-83.
  • 5
    • 0242468041 scopus 로고    scopus 로고
    • Regulation of JAK-STAT signalling in the immune system
    • Shuai K, Liu B. Regulation of JAK-STAT signalling in the immune system. Nat Rev Immunol. 2003;3:900-911.
    • (2003) Nat Rev Immunol , vol.3 , pp. 900-911
    • Shuai, K.1    Liu, B.2
  • 6
    • 0035047539 scopus 로고    scopus 로고
    • Expression and activation of a C-terminal truncated isoform of STAT5 (STAT5Delta) following interleukin 2 administration or AZT monotherapy in HIV-infected individuals
    • Bovolenta C, Camorali L, Mauri M, et al. Expression and activation of a C-terminal truncated isoform of STAT5 (STAT5Delta) following interleukin 2 administration or AZT monotherapy in HIV-infected individuals. Clin Immunol. 2001;99:75-81.
    • (2001) Clin Immunol , vol.99 , pp. 75-81
    • Bovolenta, C.1    Camorali, L.2    Mauri, M.3
  • 7
    • 10144258658 scopus 로고    scopus 로고
    • Deletion of the carboxyl-terminal transactivation domain of MGF-Stat5 results in sustained DNA binding and a dominant negative phenotype
    • Moriggl R, Gouilleux-Gruart V, Jahne R, et al. Deletion of the carboxyl-terminal transactivation domain of MGF-Stat5 results in sustained DNA binding and a dominant negative phenotype. Mol Cell Biol. 1996;16:5691-5700.
    • (1996) Mol Cell Biol , vol.16 , pp. 5691-5700
    • Moriggl, R.1    Gouilleux-Gruart, V.2    Jahne, R.3
  • 8
    • 0032516816 scopus 로고    scopus 로고
    • Positive selection of apoptosis-resistant cells correlates with activation of dominant-negative STAT5
    • Bovolenta C, Testolin L, Benussi L, Lievens PM, Liboi E. Positive selection of apoptosis-resistant cells correlates with activation of dominant-negative STAT5. J Biol Chem. 1998;273:20779-20784.
    • (1998) J Biol Chem , vol.273 , pp. 20779-20784
    • Bovolenta, C.1    Testolin, L.2    Benussi, L.3    Lievens, P.M.4    Liboi, E.5
  • 9
    • 0032831735 scopus 로고    scopus 로고
    • Stat5a and Stat5b: Fraternal twins of signal transduction and transcriptional activation
    • Grimley PM, Dong F, Rui H. Stat5a and Stat5b: fraternal twins of signal transduction and transcriptional activation. Cytokine Growth Factor Rev. 1999;10:131-157.
    • (1999) Cytokine Growth Factor Rev , vol.10 , pp. 131-157
    • Grimley, P.M.1    Dong, F.2    Rui, H.3
  • 10
    • 0032567042 scopus 로고    scopus 로고
    • Host control of HIV-1 parasitism in T cells by the nuclear factor of activated T cells
    • Kinoshita S, Chen BK, Kaneshima H, Nolan GP. Host control of HIV-1 parasitism in T cells by the nuclear factor of activated T cells. Cell. 1998;95: 595-604.
    • (1998) Cell , vol.95 , pp. 595-604
    • Kinoshita, S.1    Chen, B.K.2    Kaneshima, H.3    Nolan, G.P.4
  • 11
    • 0030939152 scopus 로고    scopus 로고
    • The T cell activation factor NF-ATc positively regulates HIV-1 replication and gene expression in T cells
    • Kinoshita S, Su L, Amano M, Timmerman LA, Kaneshima H, Nolan GP. The T cell activation factor NF-ATc positively regulates HIV-1 replication and gene expression in T cells. Immunity. 1997;6:235-244.
    • (1997) Immunity , vol.6 , pp. 235-244
    • Kinoshita, S.1    Su, L.2    Amano, M.3    Timmerman, L.A.4    Kaneshima, H.5    Nolan, G.P.6
  • 12
    • 0030754923 scopus 로고    scopus 로고
    • Characterization of nuclear proteins that bind to the regulatory TGATTGGC motif in the human immunodeficiency virus type 1 long terminal repeat
    • Schwartz C, Canonne-Hergaux F, Aunis D, Schaeffer E. Characterization of nuclear proteins that bind to the regulatory TGATTGGC motif in the human immunodeficiency virus type 1 long terminal repeat. Nucleic Acids Res. 1997;25: 1177-1184.
    • (1997) Nucleic Acids Res , vol.25 , pp. 1177-1184
    • Schwartz, C.1    Canonne-Hergaux, F.2    Aunis, D.3    Schaeffer, E.4
  • 13
    • 0037141146 scopus 로고    scopus 로고
    • Modulation of human immunodeficiency virus 1 replication by interferon regulatory factors
    • Sgarbanti M, Borsetti A, Moscufo N, et al. Modulation of human immunodeficiency virus 1 replication by interferon regulatory factors. J Exp Med. 2002;195:1359-1370.
    • (2002) J Exp Med , vol.195 , pp. 1359-1370
    • Sgarbanti, M.1    Borsetti, A.2    Moscufo, N.3
  • 14
    • 0025837425 scopus 로고
    • DNase I-hypersensitive sites are associated with both long terminal repeats and with the intragenic enhancer of integrated human immunodeficiency virus type 1
    • Verdin E. DNase I-hypersensitive sites are associated with both long terminal repeats and with the intragenic enhancer of integrated human immunodeficiency virus type 1. J Virol. 1991;65: 6790-6799.
    • (1991) J Virol , vol.65 , pp. 6790-6799
    • Verdin, E.1
  • 15
    • 0025324535 scopus 로고
    • Identification and characterization of an enhancer in the coding region of the genome of human immunodeficiency virus type 1
    • Verdin E, Becker N, Bex F, Droogmans L, Burny A. Identification and characterization of an enhancer in the coding region of the genome of human immunodeficiency virus type 1. Proc Natl Acad Sci U S A. 1990;87:4874-4878.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 4874-4878
    • Verdin, E.1    Becker, N.2    Bex, F.3    Droogmans, L.4    Burny, A.5
  • 16
    • 0025841915 scopus 로고
    • The intragenic enhancer of human immunodeficiency virus type 1 contains functional AP-1 binding sites
    • Van Lint C, Burny A, Verdin E. The intragenic enhancer of human immunodeficiency virus type 1 contains functional AP-1 binding sites. J Virol. 1991;65:7066-7072.
    • (1991) J Virol , vol.65 , pp. 7066-7072
    • Van Lint, C.1    Burny, A.2    Verdin, E.3
  • 17
    • 0030788299 scopus 로고    scopus 로고
    • Transcription factor binding sites downstream of the human immunodeficiency virus type 1 transcription start site are important for virus infectivity
    • Van Lint C, Amella CA, Emiliani S, John M, Jie T, Verdin E. Transcription factor binding sites downstream of the human immunodeficiency virus type 1 transcription start site are important for virus infectivity. J Virol. 1997;71:6113-6127.
    • (1997) J Virol , vol.71 , pp. 6113-6127
    • Van Lint, C.1    Amella, C.A.2    Emiliani, S.3    John, M.4    Jie, T.5    Verdin, E.6
  • 18
    • 0032907269 scopus 로고    scopus 로고
    • A selective defect of IFN-gamma- but not of IFN-alpha-induced JAK/STAT pathway in a subset of U937 clones prevents the antiretroviral effect of IFN-gamma against HIV-1
    • Bovolenta C, Lorini AL, Mantelli B, et al. A selective defect of IFN-gamma- but not of IFN-alpha-induced JAK/STAT pathway in a subset of U937 clones prevents the antiretroviral effect of IFN-gamma against HIV-1. J Immunol. 1999;162:323-330.
    • (1999) J Immunol , vol.162 , pp. 323-330
    • Bovolenta, C.1    Lorini, A.L.2    Mantelli, B.3
  • 19
    • 5444263178 scopus 로고    scopus 로고
    • Role of cytokines and chemokines in the regulation of innate immunity and HIV infection
    • Alfano M, Poli G. Role of cytokines and chemokines in the regulation of innate immunity and HIV infection. Mol Immunol. 2005;42:161-182.
    • (2005) Mol Immunol , vol.42 , pp. 161-182
    • Alfano, M.1    Poli, G.2
  • 20
    • 30044445017 scopus 로고    scopus 로고
    • The gammac-cytokine regulated transcription factor, STAT5, increases HIV-1 production in primary CD4 T cells
    • Selliah N, Zhang M, DeSimone D, et al. The gammac-cytokine regulated transcription factor, STAT5, increases HIV-1 production in primary CD4 T cells. Virology. 2006;344:283-291.
    • (2006) Virology , vol.344 , pp. 283-291
    • Selliah, N.1    Zhang, M.2    DeSimone, D.3
  • 21
    • 13744259064 scopus 로고    scopus 로고
    • IL-7 is a potent and proviral strain-specific inducer of latent HIV-1 cellular reservoirs of infected individuals on virally suppressive HAART
    • Wang FX, Xu Y, Sullivan J, et al. IL-7 is a potent and proviral strain-specific inducer of latent HIV-1 cellular reservoirs of infected individuals on virally suppressive HAART. J Clin Invest. 2005;115:128-137.
    • (2005) J Clin Invest , vol.115 , pp. 128-137
    • Wang, F.X.1    Xu, Y.2    Sullivan, J.3
  • 22
    • 0036720404 scopus 로고    scopus 로고
    • Modalities of interleukin-7-induced human immunodeficiency virus permissiveness in quiescent T lymphocytes
    • Ducrey-Rundquist O, Guyader M, Trono D. Modalities of interleukin-7-induced human immunodeficiency virus permissiveness in quiescent T lymphocytes. J Virol. 2002;76:9103-9111.
    • (2002) J Virol , vol.76 , pp. 9103-9111
    • Ducrey-Rundquist, O.1    Guyader, M.2    Trono, D.3
  • 23
    • 0034637473 scopus 로고    scopus 로고
    • Constitutive activation of STAT5 by a point mutation in the SH2 domain
    • Ariyoshi K, Nosaka T, Yamada K, et al. Constitutive activation of STAT5 by a point mutation in the SH2 domain. J Biol Chem. 2000;275:24407-24413.
    • (2000) J Biol Chem , vol.275 , pp. 24407-24413
    • Ariyoshi, K.1    Nosaka, T.2    Yamada, K.3
  • 24
    • 18744427797 scopus 로고    scopus 로고
    • Constitutively active STAT5A and STAT5B in vitro and in vivo: Mutation of STAT5 is not a frequent cause of leukemogenesis
    • Yamada K, Ariyoshi K, Onishi M, et al. Constitutively active STAT5A and STAT5B in vitro and in vivo: mutation of STAT5 is not a frequent cause of leukemogenesis. Int J Hematol. 2000;71:46-54.
    • (2000) Int J Hematol , vol.71 , pp. 46-54
    • Yamada, K.1    Ariyoshi, K.2    Onishi, M.3
  • 25
    • 25144493560 scopus 로고    scopus 로고
    • Vallanti G, Lupo R, Federico M, Mavilio F, Bovolenta C. T Lymphocytes transduced with a lentiviral vector expressing F12-Vif are protected from HIV-1 infection in an APOBEC3G-independent manner. Mol Ther. 2005;12:697-706.
    • Vallanti G, Lupo R, Federico M, Mavilio F, Bovolenta C. T Lymphocytes transduced with a lentiviral vector expressing F12-Vif are protected from HIV-1 infection in an APOBEC3G-independent manner. Mol Ther. 2005;12:697-706.
  • 26
    • 0347624643 scopus 로고    scopus 로고
    • Regulation of HIV-1 gene expression by histone acetylation and factor recruitment at the LTR promoter
    • Lusic M, Marcello A, Cereseto A, Giacca M. Regulation of HIV-1 gene expression by histone acetylation and factor recruitment at the LTR promoter. Embo J. 2003;22:6550-6561.
    • (2003) Embo J , vol.22 , pp. 6550-6561
    • Lusic, M.1    Marcello, A.2    Cereseto, A.3    Giacca, M.4
  • 27
    • 10744222905 scopus 로고    scopus 로고
    • Evaluation of the impact of highly active antiretroviral therapy on immune recovery in antiretroviral naive patients
    • Al-Harthi L, Voris J, Patterson BK, et al. Evaluation of the impact of highly active antiretroviral therapy on immune recovery in antiretroviral naive patients. HIV Med. 2004;5:55-65.
    • (2004) HIV Med , vol.5 , pp. 55-65
    • Al-Harthi, L.1    Voris, J.2    Patterson, B.K.3
  • 28
    • 0010472999 scopus 로고
    • Tumor necrosis factor alpha induces expression of human immunodeficiency virus in a chronically infected T-cell clone
    • Folks TM, Clouse KA, Justement J, et al. Tumor necrosis factor alpha induces expression of human immunodeficiency virus in a chronically infected T-cell clone. Proc Natl Acad Sci U S A. 1989;86:2365-2368.
    • (1989) Proc Natl Acad Sci U S A , vol.86 , pp. 2365-2368
    • Folks, T.M.1    Clouse, K.A.2    Justement, J.3
  • 31
    • 0023508507 scopus 로고
    • Cytokine-induced expression of HIV-1 in a chronically infected promonocyte cell line
    • Folks TM, Justement J, Kinter A, Dinarello CA, Fauci AS. Cytokine-induced expression of HIV-1 in a chronically infected promonocyte cell line. Science. 1987;238:800-802.
    • (1987) Science , vol.238 , pp. 800-802
    • Folks, T.M.1    Justement, J.2    Kinter, A.3    Dinarello, C.A.4    Fauci, A.S.5
  • 32
    • 0033600851 scopus 로고    scopus 로고
    • Yang X, Chen Y, Gabuzda D. ERK MAP kinase links cytokine signals to activation of latent HIV-1 infection by stimulating a cooperative interaction of AP-1 and NF- kappaB. J Biol Chem. 1999;274: 27981-27988.
    • Yang X, Chen Y, Gabuzda D. ERK MAP kinase links cytokine signals to activation of latent HIV-1 infection by stimulating a cooperative interaction of AP-1 and NF- kappaB. J Biol Chem. 1999;274: 27981-27988.
  • 34
    • 0035163156 scopus 로고    scopus 로고
    • Interleukin-6 and glucocorticoids synergistically induce human immunodeficiency virus type-1 expression in chronically infected U1 cells by a long terminal repeat independent post-transcriptional mechanism
    • Kinter AL, Biswas P, Alfano M, et al. Interleukin-6 and glucocorticoids synergistically induce human immunodeficiency virus type-1 expression in chronically infected U1 cells by a long terminal repeat independent post-transcriptional mechanism. Mol Med. 2001;7:668-678.
    • (2001) Mol Med , vol.7 , pp. 668-678
    • Kinter, A.L.1    Biswas, P.2    Alfano, M.3
  • 35
    • 30744471901 scopus 로고    scopus 로고
    • Pertussis toxin B-oligomer suppresses IL-6 induced HIV-1 and chemokine expression in chronically infected U1 cells via inhibition of activator protein 1
    • Rizzi C, Crippa MP, Jeeninga RE, et al. Pertussis toxin B-oligomer suppresses IL-6 induced HIV-1 and chemokine expression in chronically infected U1 cells via inhibition of activator protein 1. J Immunol. 2006;176:999-1006.
    • (2006) J Immunol , vol.176 , pp. 999-1006
    • Rizzi, C.1    Crippa, M.P.2    Jeeninga, R.E.3
  • 36
    • 0035930515 scopus 로고    scopus 로고
    • Poxvirus infection rapidly activates tyrosine kinase signal transduction
    • Masters J, Hinek AA, Uddin S, et al. Poxvirus infection rapidly activates tyrosine kinase signal transduction. J Biol Chem. 2001;276:48371-48375.
    • (2001) J Biol Chem , vol.276 , pp. 48371-48375
    • Masters, J.1    Hinek, A.A.2    Uddin, S.3
  • 37
    • 0034327770 scopus 로고    scopus 로고
    • Functional uncoupling of the Janus kinase 3-Stat5 pathway in malignant growth of human T cell leukemia virus type 1-transformed human T cells
    • Kirken RA, Erwin RA, Wang L, Wang Y, Rui H, Farrar WL. Functional uncoupling of the Janus kinase 3-Stat5 pathway in malignant growth of human T cell leukemia virus type 1-transformed human T cells. J Immunol. 2000;165:5097-5104.
    • (2000) J Immunol , vol.165 , pp. 5097-5104
    • Kirken, R.A.1    Erwin, R.A.2    Wang, L.3    Wang, Y.4    Rui, H.5    Farrar, W.L.6
  • 38
    • 28044461950 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling-1 selectively inhibits LPS-induced IL-6 production by regulating JAK-STAT
    • Kimura A, Naka T, Muta T, et al. Suppressor of cytokine signaling-1 selectively inhibits LPS-induced IL-6 production by regulating JAK-STAT. Proc Natl Acad Sci U S A. 2005;102:17089-17094.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 17089-17094
    • Kimura, A.1    Naka, T.2    Muta, T.3
  • 39
    • 30044445017 scopus 로고    scopus 로고
    • The gammac-cytokine regulated transcription factor, STAT5, increases HIV-1 production in primary CD4 T cells
    • Selliah N, Zhang M, Desimone D, et al. The gammac-cytokine regulated transcription factor, STAT5, increases HIV-1 production in primary CD4 T cells. Virology. 2006;344:283-291.
    • (2006) Virology , vol.344 , pp. 283-291
    • Selliah, N.1    Zhang, M.2    Desimone, D.3
  • 40
    • 0022967777 scopus 로고
    • CD8+ lymphocytes can control HIV infection in vitro by suppressing virus replication
    • Walker CM, Moody DJ, Stites DP, Levy JA. CD8+ lymphocytes can control HIV infection in vitro by suppressing virus replication. Science. 1986;234: 1563-1566.
    • (1986) Science , vol.234 , pp. 1563-1566
    • Walker, C.M.1    Moody, D.J.2    Stites, D.P.3    Levy, J.A.4
  • 41
    • 0029417004 scopus 로고
    • Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells
    • Cocchi F, DeVico AL, Garzino-Demo A, Arya SK, Gallo RC, Lusso P. Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells. Science. 1995;270:1811-1815.
    • (1995) Science , vol.270 , pp. 1811-1815
    • Cocchi, F.1    DeVico, A.L.2    Garzino-Demo, A.3    Arya, S.K.4    Gallo, R.C.5    Lusso, P.6
  • 42
    • 0032128276 scopus 로고    scopus 로고
    • Natural killer cells from human immunodeficiency virus (HIV)-infected individuals are an important source of CC-chemokines and suppress HIV-1 entry and replication in vitro
    • Oliva A, Kinter AL, Vaccarezza M, et al. Natural killer cells from human immunodeficiency virus (HIV)-infected individuals are an important source of CC-chemokines and suppress HIV-1 entry and replication in vitro. J Clin Invest. 1998;102:223-231.
    • (1998) J Clin Invest , vol.102 , pp. 223-231
    • Oliva, A.1    Kinter, A.L.2    Vaccarezza, M.3
  • 43
    • 0033586444 scopus 로고    scopus 로고
    • Role of peripheral blood mononuclear cell subsets of seronegative donors in HIV replication: Suppression by CD8+ and CD16+ cells and enhancement by CD14+ monocytes
    • Alfano M, Veglia F, Poli G. Role of peripheral blood mononuclear cell subsets of seronegative donors in HIV replication: suppression by CD8+ and CD16+ cells and enhancement by CD14+ monocytes. AIDS Res Hum Retroviruses. 1999; 15:489-491.
    • (1999) AIDS Res Hum Retroviruses , vol.15 , pp. 489-491
    • Alfano, M.1    Veglia, F.2    Poli, G.3
  • 45
    • 0030793345 scopus 로고    scopus 로고
    • Functionally distinct isoforms of STAT5 are generated by protein processing
    • Azam M, Lee C, Strehlow I, Schindler C. Functionally distinct isoforms of STAT5 are generated by protein processing. Immunity. 1997;6:691-701.
    • (1997) Immunity , vol.6 , pp. 691-701
    • Azam, M.1    Lee, C.2    Strehlow, I.3    Schindler, C.4
  • 46
    • 0035029411 scopus 로고    scopus 로고
    • Truncated STAT proteins are prevalent at relapse of acute myeloid leukemia
    • Xia Z, Sait SN, Baer MR, et al. Truncated STAT proteins are prevalent at relapse of acute myeloid leukemia. Leuk Res. 2001;25:473-482.
    • (2001) Leuk Res , vol.25 , pp. 473-482
    • Xia, Z.1    Sait, S.N.2    Baer, M.R.3
  • 47
    • 0346059585 scopus 로고    scopus 로고
    • Dysregulated expression of COOH-terminally truncated Stat5 and loss of IL2-inducible Stat5-dependent gene expression in Sezary Syndrome
    • Mitchell TJ, Whittaker SJ, John S. Dysregulated expression of COOH-terminally truncated Stat5 and loss of IL2-inducible Stat5-dependent gene expression in Sezary Syndrome. Cancer Res. 2003;63:9048-9054.
    • (2003) Cancer Res , vol.63 , pp. 9048-9054
    • Mitchell, T.J.1    Whittaker, S.J.2    John, S.3
  • 48
    • 33749241886 scopus 로고    scopus 로고
    • Barash I. Stat5 in the mammary gland: Controlling normal development and cancer. J Cell Physiol. 2006;209:305-313.
    • Barash I. Stat5 in the mammary gland: Controlling normal development and cancer. J Cell Physiol. 2006;209:305-313.
  • 49
    • 0032520260 scopus 로고    scopus 로고
    • Carboxyl-truncated STAT5beta is generated by a nucleus-associated serine protease in early hematopoietic progenitors
    • Meyer J, Jucker M, Ostertag W, Stocking C. Carboxyl-truncated STAT5beta is generated by a nucleus-associated serine protease in early hematopoietic progenitors. Blood. 1998;91:1901-1908.
    • (1998) Blood , vol.91 , pp. 1901-1908
    • Meyer, J.1    Jucker, M.2    Ostertag, W.3    Stocking, C.4
  • 50
    • 0033578712 scopus 로고    scopus 로고
    • Characterization of the Stat5 protease
    • Lee C, Piazza F, Brutsaert S, et al. Characterization of the Stat5 protease. J Biol Chem. 1999; 274:26767-26775.
    • (1999) J Biol Chem , vol.274 , pp. 26767-26775
    • Lee, C.1    Piazza, F.2    Brutsaert, S.3
  • 51
    • 0035866398 scopus 로고    scopus 로고
    • A novel serine-dependent proteolytic activity is responsible for truncated signal transducer and activator of transcription proteins in acute myeloid leukemia blasts
    • Xia Z, Salzler RR, Kunz DP, et al. A novel serine-dependent proteolytic activity is responsible for truncated signal transducer and activator of transcription proteins in acute myeloid leukemia blasts. Cancer Res. 2001;61:1747-1753.
    • (2001) Cancer Res , vol.61 , pp. 1747-1753
    • Xia, Z.1    Salzler, R.R.2    Kunz, D.P.3
  • 52
    • 0034663045 scopus 로고    scopus 로고
    • Myeloid differentiation of FdCP1 cells is dependent on Stat5 processing
    • Piazza F, Valens J, Lagasse E, Schindler C. Myeloid differentiation of FdCP1 cells is dependent on Stat5 processing. Blood. 2000;96:1358-1365.
    • (2000) Blood , vol.96 , pp. 1358-1365
    • Piazza, F.1    Valens, J.2    Lagasse, E.3    Schindler, C.4
  • 53
    • 0036521607 scopus 로고    scopus 로고
    • Granulocyte-macrophage colony-stimulating factor (GM-CSF)-induced STAT5 activation and target-gene expression during human monocyte/macrophage differentiation
    • Lehtonen A, Matikainen S, Miettinen M, Julkunen I. Granulocyte-macrophage colony-stimulating factor (GM-CSF)-induced STAT5 activation and target-gene expression during human monocyte/macrophage differentiation. J Leukoc Biol. 2002; 71:511-519.
    • (2002) J Leukoc Biol , vol.71 , pp. 511-519
    • Lehtonen, A.1    Matikainen, S.2    Miettinen, M.3    Julkunen, I.4
  • 54
    • 0036435689 scopus 로고    scopus 로고
    • Carboxy-terminal truncated STAT5 is induced by interleukin-2 and GM-CSF in human neutrophils
    • Epling-Burnette PK, Garcia R, Bai F, et al. Carboxy-terminal truncated STAT5 is induced by interleukin-2 and GM-CSF in human neutrophils. Cell Immunol. 2002;217:1-11.
    • (2002) Cell Immunol , vol.217 , pp. 1-11
    • Epling-Burnette, P.K.1    Garcia, R.2    Bai, F.3
  • 55
    • 0034142208 scopus 로고    scopus 로고
    • A small amphipathic alpha-helical region is required for transcriptional activities and proteasome-dependent turnover of the tyrosine-phosphorylated Stat5
    • Wang D, Moriggl R, Stravopodis D, et al. A small amphipathic alpha-helical region is required for transcriptional activities and proteasome-dependent turnover of the tyrosine-phosphorylated Stat5. Embo J. 2000;19:392-399.
    • (2000) Embo J , vol.19 , pp. 392-399
    • Wang, D.1    Moriggl, R.2    Stravopodis, D.3
  • 56
    • 0022580049 scopus 로고
    • Induction of HTLV-III/LAV from a nonvirus-producing T-cell line: Implications for latency
    • Folks T, Powell DM, Lightfoote MM, Benn S, Martin MA, Fauci AS. Induction of HTLV-III/LAV from a nonvirus-producing T-cell line: implications for latency. Science. 1986;231:600-602.
    • (1986) Science , vol.231 , pp. 600-602
    • Folks, T.1    Powell, D.M.2    Lightfoote, M.M.3    Benn, S.4    Martin, M.A.5    Fauci, A.S.6
  • 57
    • 0034908521 scopus 로고    scopus 로고
    • BCR-ABL fails to inhibit apoptosis in U937 myelomonocytic cells expressing a carboxyl-terminal truncated STAT5
    • Ahmed M, Dusanter-Fourt I, Dugray A, et al. BCR-ABL fails to inhibit apoptosis in U937 myelomonocytic cells expressing a carboxyl-terminal truncated STAT5. Leuk Lymphoma. 2001;42:445-455.
    • (2001) Leuk Lymphoma , vol.42 , pp. 445-455
    • Ahmed, M.1    Dusanter-Fourt, I.2    Dugray, A.3
  • 58
    • 0029805203 scopus 로고    scopus 로고
    • Host factors and the pathogenesis of HIV-induced disease
    • Fauci AS. Host factors and the pathogenesis of HIV-induced disease. Nature. 1996;384:529-534.
    • (1996) Nature , vol.384 , pp. 529-534
    • Fauci, A.S.1
  • 59
    • 0032577449 scopus 로고    scopus 로고
    • Viral dynamics in HIV-1 infection
    • Finzi D, Siliciano RF. Viral dynamics in HIV-1 infection. Cell. 1998;93:665-671.
    • (1998) Cell , vol.93 , pp. 665-671
    • Finzi, D.1    Siliciano, R.F.2
  • 60
    • 0032490570 scopus 로고    scopus 로고
    • Induction of HIV-1 replication in latently infected CD4+ T cells using a combination of cytokines
    • Chun TW, Engel D, Mizell SB, Ehler LA, Fauci AS. Induction of HIV-1 replication in latently infected CD4+ T cells using a combination of cytokines. J Exp Med. 1998;188:83-91.
    • (1998) J Exp Med , vol.188 , pp. 83-91
    • Chun, T.W.1    Engel, D.2    Mizell, S.B.3    Ehler, L.A.4    Fauci, A.S.5
  • 61
    • 0033532628 scopus 로고    scopus 로고
    • Cytokine signals are sufficient for HIV-1 infection of resting human T lymphocytes
    • Unutmaz D, KewalRamani VN, Marmon S, Littman DR. Cytokine signals are sufficient for HIV-1 infection of resting human T lymphocytes. J Exp Med. 1999;189:1735-1746.
    • (1999) J Exp Med , vol.189 , pp. 1735-1746
    • Unutmaz, D.1    KewalRamani, V.N.2    Marmon, S.3    Littman, D.R.4
  • 62
    • 0029045866 scopus 로고
    • Interleukin-3, granulocyte-macrophage colony-stimulating factor, and interleukin-5 transduce signals through two forms of STAT5
    • Mui AL, Wakao H, Harada N, O'Farrell AM, Miyajima A. Interleukin-3, granulocyte-macrophage colony-stimulating factor, and interleukin-5 transduce signals through two forms of STAT5. J Leukoc Biol. 1995;57:799-803.
    • (1995) J Leukoc Biol , vol.57 , pp. 799-803
    • Mui, A.L.1    Wakao, H.2    Harada, N.3    O'Farrell, A.M.4    Miyajima, A.5
  • 63
    • 0024537623 scopus 로고
    • Replication of human immunodeficiency virus in monocytes. Granulocyte/macrophage colony-stimulating factor (GM-CSF) potentiates viral production yet enhances the antiviral effect mediated by 3′-azido- 2′3′-dideoxythymidine (AZT) and other dideoxynucleoside congeners of thymidine
    • Perno CF, Yarchoan R, Cooney DA, et al. Replication of human immunodeficiency virus in monocytes. Granulocyte/macrophage colony-stimulating factor (GM-CSF) potentiates viral production yet enhances the antiviral effect mediated by 3′-azido- 2′3′-dideoxythymidine (AZT) and other dideoxynucleoside congeners of thymidine. J Exp Med. 1989;169:933-951.
    • (1989) J Exp Med , vol.169 , pp. 933-951
    • Perno, C.F.1    Yarchoan, R.2    Cooney, D.A.3
  • 64
    • 0031818184 scopus 로고    scopus 로고
    • Cytokine regulation of human immunodeficiency virus type 1 entry and replication in human monocytes/macrophages through modulation of CCR5 expression
    • Wang J, Roderiquez G, Oravecz T, Norcross MA. Cytokine regulation of human immunodeficiency virus type 1 entry and replication in human monocytes/macrophages through modulation of CCR5 expression. J Virol. 1998;72:7642-7647.
    • (1998) J Virol , vol.72 , pp. 7642-7647
    • Wang, J.1    Roderiquez, G.2    Oravecz, T.3    Norcross, M.A.4
  • 65
    • 0037084044 scopus 로고    scopus 로고
    • Granulocyte-macrophage colony-stimulating factor enhances viral load in human brain tissue: Amelioration with stavudine
    • Kandanearatchi A, Zuckerman M, Smith M, Vyakarnam A, Everall IP. Granulocyte-macrophage colony-stimulating factor enhances viral load in human brain tissue: amelioration with stavudine. AIDS. 2002;16:413-420.
    • (2002) AIDS , vol.16 , pp. 413-420
    • Kandanearatchi, A.1    Zuckerman, M.2    Smith, M.3    Vyakarnam, A.4    Everall, I.P.5
  • 66
    • 0029096937 scopus 로고
    • Suppression of HIV replication in human monocyte-derived macrophages induced by granulocyte/macrophage colony-stimulating factor
    • Matsuda S, Akagawa K, Honda M, Yokota Y, Takebe Y, Takemori T. Suppression of HIV replication in human monocyte-derived macrophages induced by granulocyte/macrophage colony-stimulating factor. AIDS Res Hum Retroviruses. 1995;11:1031-1038.
    • (1995) AIDS Res Hum Retroviruses , vol.11 , pp. 1031-1038
    • Matsuda, S.1    Akagawa, K.2    Honda, M.3    Yokota, Y.4    Takebe, Y.5    Takemori, T.6
  • 67
    • 0033827554 scopus 로고    scopus 로고
    • Granulocyte-macrophage colony-stimulating factor inhibits HIV-1 replication in monocyte-derived macrophages
    • Kedzierska K, Maerz A, Warby T, et al. Granulocyte-macrophage colony-stimulating factor inhibits HIV-1 replication in monocyte-derived macrophages. AIDS. 2000;14:1739-1748.
    • (2000) AIDS , vol.14 , pp. 1739-1748
    • Kedzierska, K.1    Maerz, A.2    Warby, T.3
  • 68
    • 0041622820 scopus 로고    scopus 로고
    • CSF-induced and HIV-1-mediated distinct regulation of Hck and C/EBPbeta represent a heterogeneous susceptibility of monocyte-derived macrophages to M-tropic HIV-1 infection
    • Komuro I, Yokota Y, Yasuda S, Iwamoto A, Kagawa KS. CSF-induced and HIV-1-mediated distinct regulation of Hck and C/EBPbeta represent a heterogeneous susceptibility of monocyte-derived macrophages to M-tropic HIV-1 infection. J Exp Med. 2003;198:443-453.
    • (2003) J Exp Med , vol.198 , pp. 443-453
    • Komuro, I.1    Yokota, Y.2    Yasuda, S.3    Iwamoto, A.4    Kagawa, K.S.5
  • 69
    • 0032528779 scopus 로고    scopus 로고
    • Identification of an additional isoform of STAT5 expressed in immature macrophages
    • Lokuta MA, McDowell MA, Paulnock DM. Identification of an additional isoform of STAT5 expressed in immature macrophages. J Immunol. 1998;161:1594-1597.
    • (1998) J Immunol , vol.161 , pp. 1594-1597
    • Lokuta, M.A.1    McDowell, M.A.2    Paulnock, D.M.3
  • 70
    • 0022607251 scopus 로고
    • Susceptibility of normal human lymphocytes to infection with HTLV- III/LAV
    • Folks T, Kelly J, Benn S, et al. Susceptibility of normal human lymphocytes to infection with HTLV- III/LAV. J Immunol. 1986;136:4049-4053.
    • (1986) J Immunol , vol.136 , pp. 4049-4053
    • Folks, T.1    Kelly, J.2    Benn, S.3
  • 71
    • 0028912032 scopus 로고
    • Increases in CD4 T lymphocytes with intermittent courses of interleukin-2 in patients with human immunodeficiency virus infection. A preliminary study
    • Kovacs JA, Baseler M, Dewar RJ, et al. Increases in CD4 T lymphocytes with intermittent courses of interleukin-2 in patients with human immunodeficiency virus infection. A preliminary study. N Engl J Med. 1995;332:567-575.
    • (1995) N Engl J Med , vol.332 , pp. 567-575
    • Kovacs, J.A.1    Baseler, M.2    Dewar, R.J.3
  • 72
    • 0013610170 scopus 로고    scopus 로고
    • Controlled trial of interleukin-2 infusions in patients infected with the human immunodeficiency virus
    • Kovacs JA, Vogel S, Albert JM, et al. Controlled trial of interleukin-2 infusions in patients infected with the human immunodeficiency virus. N Engl J Med. 1996;335:1350-1356.
    • (1996) N Engl J Med , vol.335 , pp. 1350-1356
    • Kovacs, J.A.1    Vogel, S.2    Albert, J.M.3
  • 73
    • 0033836422 scopus 로고    scopus 로고
    • Pooled analysis of 3 randomized, controlled trials of interleukin-2 therapy in adult human immunodeficiency virus type 1 disease
    • Emery S, Capra WB, Cooper DA, et al. Pooled analysis of 3 randomized, controlled trials of interleukin-2 therapy in adult human immunodeficiency virus type 1 disease. J Infect Dis. 2000; 182:428-434.
    • (2000) J Infect Dis , vol.182 , pp. 428-434
    • Emery, S.1    Capra, W.B.2    Cooper, D.A.3
  • 74
    • 0035873085 scopus 로고    scopus 로고
    • Efficacy of low-dose intermittent subcutaneous interleukin (IL) - 2 in antiviral drug - experienced human immunodeficiency virus - infected persons with detectable virus load: A controlled study of 3 il-2 regimens with antiviral drug therapy
    • Tambussi G, Ghezzi S, Nozza S, et al. Efficacy of low-dose intermittent subcutaneous interleukin (IL) - 2 in antiviral drug - experienced human immunodeficiency virus - infected persons with detectable virus load: a controlled study of 3 il-2 regimens with antiviral drug therapy. J Infect Dis. 2001;183:1476-1484.
    • (2001) J Infect Dis , vol.183 , pp. 1476-1484
    • Tambussi, G.1    Ghezzi, S.2    Nozza, S.3
  • 75
    • 10744226358 scopus 로고    scopus 로고
    • A controlled trial of granulocyte macrophage-colony stimulating factor during interruption of HAART
    • Fagard C, Le Braz M, Gunthard H, et al. A controlled trial of granulocyte macrophage-colony stimulating factor during interruption of HAART. AIDS. 2003;17:1487-1492.
    • (2003) AIDS , vol.17 , pp. 1487-1492
    • Fagard, C.1    Le Braz, M.2    Gunthard, H.3
  • 76
    • 27344439362 scopus 로고    scopus 로고
    • Granulocyte-macrophage colony-stimulating factor as an immune-based therapy in HIV infection
    • Brown PA, Angel JB. Granulocyte-macrophage colony-stimulating factor as an immune-based therapy in HIV infection. J Immune Based Ther Vaccines. 2005;3:3.
    • (2005) J Immune Based Ther Vaccines , vol.3 , pp. 3
    • Brown, P.A.1    Angel, J.B.2
  • 77
    • 0033787449 scopus 로고    scopus 로고
    • A randomized, placebo-controlled trial of granulocyte-macrophage colony-stimulating factor and nucleoside analogue therapy in AIDS
    • Brites C, Gilbert MJ, Pedral-Sampaio D, et al. A randomized, placebo-controlled trial of granulocyte-macrophage colony-stimulating factor and nucleoside analogue therapy in AIDS. J Infect Dis. 2000;182:1531-1535.
    • (2000) J Infect Dis , vol.182 , pp. 1531-1535
    • Brites, C.1    Gilbert, M.J.2    Pedral-Sampaio, D.3
  • 78
    • 9144224219 scopus 로고    scopus 로고
    • Granulocyte-macrophage colony-stimulating factor induces modest increases in plasma human immunodeficiency virus (HIV) type 1 RNA levels and CD4+ lymphocyte counts in patients with uncontrolled HIV infection
    • Jacobson JM, Lederman MM, Spritzler J, et al. Granulocyte-macrophage colony-stimulating factor induces modest increases in plasma human immunodeficiency virus (HIV) type 1 RNA levels and CD4+ lymphocyte counts in patients with uncontrolled HIV infection. J Infect Dis. 2003;188: 1804-1814.
    • (2003) J Infect Dis , vol.188 , pp. 1804-1814
    • Jacobson, J.M.1    Lederman, M.M.2    Spritzler, J.3
  • 79
    • 20044397011 scopus 로고    scopus 로고
    • WHO clinical staging of HIV infection and disease, tuberculosis and eligibility for antiretroviral treatment: Relationship to CD4 lymphocyte counts
    • Teck R, Ascurra O, Gomani P, et al. WHO clinical staging of HIV infection and disease, tuberculosis and eligibility for antiretroviral treatment: relationship to CD4 lymphocyte counts. Int J Tuberc Lung Dis. 2005;9:258-262.
    • (2005) Int J Tuberc Lung Dis , vol.9 , pp. 258-262
    • Teck, R.1    Ascurra, O.2    Gomani, P.3


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