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Volumn , Issue 23, 2007, Pages 2390-2392

Selective disaccharide binding by a macrotetracyclic receptor

Author keywords

[No Author keywords available]

Indexed keywords

CARBOHYDRATE; CHLOROFORM; DISACCHARIDE; GLUCOSIDE; MALTOSE; METHANE; MONOSACCHARIDE; OLIGOMER; SOLVENT;

EID: 34250007195     PISSN: 13597345     EISSN: None     Source Type: Journal    
DOI: 10.1039/b618776e     Document Type: Article
Times cited : (31)

References (39)
  • 16
    • 33750168668 scopus 로고    scopus 로고
    • We use the term "biomimetic" for receptors which, as a minimum criterion, operate through non-covalent interactions. Effective but non-biomimetic carbohydrate recognition is possible through reversible covalent B-O bond formation. See ref. 3a and:
    • O. Francesconi A. Ienco G. Moneti C. Nativi S. Roelens Angew. Chem., Int. Ed. 2006 45 6693
    • (2006) Angew. Chem., Int. Ed. , vol.45 , pp. 6693
    • Francesconi, O.1    Ienco, A.2    Moneti, G.3    Nativi, C.4    Roelens, S.5
  • 27
    • 33749141484 scopus 로고    scopus 로고
    • For other systems with notable oligosaccharide binding properties, see ref. 3c and:
    • M. Mazik A. König J. Org. Chem. 2006 71 7854
    • (2006) J. Org. Chem. , vol.71 , pp. 7854
    • Mazik, M.1    König, A.2
  • 35
    • 34249998658 scopus 로고    scopus 로고
    • For details of the synthesis and binding experiments, see Supplementary Information
    • For details of the synthesis and binding experiments, see Supplementary Information
  • 36
    • 34250012293 scopus 로고    scopus 로고
    • For further discussion see Supplementary Information
    • For further discussion see Supplementary Information
  • 37
    • 34250025383 scopus 로고    scopus 로고
    • Monte Carlo Molecular Mechanics (MCMM) searches were performed using MacroModel 9.0 (Maestro 7.0 interface), employing the MMFFs force field and GB/SA chloroform solvation
    • Monte Carlo Molecular Mechanics (MCMM) searches were performed using MacroModel 9.0 (Maestro 7.0 interface), employing the MMFFs force field and GB/SA chloroform solvation
  • 39
    • 34547949856 scopus 로고
    • Comparisons are difficult as the stoichiometries, and therefore the units of the binding constants, are different. However, an estimate can be obtained by comparing the concentrations at which guests occupied 50% of receptor binding sites during the titrations. For 4a and 10 the figures are 1.4 mM and 25 mM respectively. By this measure, the receptor favours disaccharide 4a by a factor of 18
    • M. J. Hynes J. Chem. Soc., Dalton Trans. 1993 311
    • (1993) J. Chem. Soc., Dalton Trans. , pp. 311
    • Hynes, M.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.