Irreversible binding of a novel phenylisothiocyanate tropane analog to monoamine transporters in rat brain

Biochemical Pharmacology

Volumn 74, Issue 2, 2007, Pages 336-344

  Murthy, Vishakantha ^a   Davies, Huw M L ^b   Hedley, Simon J ^b   Childers, Steven R ^a  

^a WAKE FOREST UNIVERSITY HEALTH SCIENCES   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

Author keywords

Cocaine; Dopamine transporter; Norepinephrine transporter; Phenylisothiocyanate; Serotonin transporter; Tropane

Indexed keywords

2BETA PROPANOYL 3BETA (2 NAPHTHYL) 8 [(4 ISOTHIOCYANATO)BENZYL]NORTROPANE; 2BETA PROPANOYL 3BETA (6 IODO 2 NAPHTHYL) 8 [(4 ISOTHIOCYANATO)BENZYL]NORTROPANE; 3BETA (2 NAPHTHYL) 2BETA PROPIONYLTROPANE; 3BETA (4 IODOPHENYL) 2BETA TROPANECARBOXYLIC ACID METHYL ESTER; CITALOPRAM; COCAINE; DOPAMINE TRANSPORTER; HD 205; HD 244; IODINE 125; MEMBRANE PROTEIN; NISOXETINE; NORADRENALIN TRANSPORTER; PHENYL ISOTHIOCYANATE; SEROTONIN TRANSPORTER; TRITIUM; TROPANE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN; CHEMICAL STRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOPAMINERGIC SYSTEM; DRUG BINDING SITE; DRUG POTENCY; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOREACTIVITY; ISOTOPE LABELING; LIGAND BINDING; NEUROPHARMACOLOGY; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; RADIOIODINATION; RAT; SEROTONINERGIC SYSTEM; WESTERN BLOTTING;

ANIMALS; BRAIN; COCAINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; ISOTHIOCYANATES; MALE; NOREPINEPHRINE PLASMA MEMBRANE TRANSPORT PROTEINS; RATS; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; TROPANES;

EID: 34249977870     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2007.04.019     Document Type: Article

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