Mechanism of the myosin catalyzed hydrolysis of ATP as rationalized by molecular modeling

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 17, 2007, Pages 7057-7061

  Grigorenko, Bella L ^a   Rogov, Alexander V ^a   Topol, Igor A ^b   Burt, Stanley K ^b   Martinez, Hugo M ^c   Nemukhin, Alexander V ^a  

^a MOSCOW STATE UNIVERSITY   (Russian Federation)

^b SAIC FREDERICK INC   (United States)

^c Computational Biology Consulting ^*  (United States)

Author keywords

ATP hydrolysis; Energy profile; Enzymatic catalysis; Quantum mechanics and molecular mechanics simulations

Indexed keywords

ADENOSINE TRIPHOSPHATE; MYOSIN;

AB INITIO CALCULATION; ARTICLE; CHEMICAL BOND; CHEMICAL REACTION; CRYSTAL STRUCTURE; ENERGY; ENZYME SUBSTRATE COMPLEX; HYDROGEN BOND; HYDROLYSIS; MOLECULAR MECHANICS; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STRUCTURE; QUANTUM MECHANICS; SIMULATION; ANIMAL; BIOMECHANICS; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; CONFORMATION; DICTYOSTELIUM; METABOLISM; QUANTUM THEORY; THERMODYNAMICS;

ADENOSINE TRIPHOSPHATE; ANIMALS; BIOMECHANICS; CATALYSIS; COMPUTER SIMULATION; DICTYOSTELIUM; HYDROLYSIS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MYOSINS; QUANTUM THEORY; THERMODYNAMICS;

EID: 34249844500     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0701727104     Document Type: Article

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