Selective re-routing of prion protein to proteasomes and alteration of its vesicular secretion prevent PrPSc formation

Journal of Neurochemistry

Volumn 101, Issue 6, 2007, Pages 1516-1526

  Filesi, Ilaria ^a   Cardinale, Alessio ^b   Mattei, Sonia ^a   Biocca, Silvia ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b IRCCS SAN RAFFAELE PISANA   (Italy)

Author keywords

Exosomes; Intrabody; NGF; Prion; Proteasome; scFv; Scrapie

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; LACTACYSTIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 7A12; MONOCLONAL ANTIBODY 8H4; MONOCLONAL ANTIBODY 9E10; NERVE GROWTH FACTOR RECEPTOR; PRION PROTEIN; PROTEASOME; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL VACUOLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; GLYCOSYLATION; INTRACELLULAR SPACE; NONHUMAN; PRION DISEASE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PROCESSING; PROTEIN SECRETION; PROTEIN STABILITY; PROTEIN SYNTHESIS; RAT;

ANIMALS; CELL COMPARTMENTATION; CHLOROQUINE; IMMUNOGLOBULIN VARIABLE REGION; MICE; PC12 CELLS; PRION DISEASES; PROTEASE INHIBITORS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN TRANSPORT; PRPC PROTEINS; PRPSC PROTEINS; RATS;

EID: 34249817866     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2006.04439.x     Document Type: Article

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