Transgenic expression of human INS gene in Ins1/Ins2 double knockout mice leads to insulin underproduction and diabetes in some male mice

Frontiers in Bioscience

Volumn 12, Issue 5, 2007, Pages 1586-1593

  Karaca, Melis ^a   Durel, Béatrice ^a   Languille, Laëtitia ^a   Lamotte, Luciane ^a   Tourrel Cuzin, Cécile ^b   Leroux, Loïc ^a   Sleymane, Gretta Abou ^a   Saint Just, Susan ^a   Bucchini, Danielle ^a   Ktorza, Alain ^b   Joshi, Rajiv L ^a  

^a INSTITUT COCHIN   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

Diabetes; Glucose homeostasis; Insulin genes; Knockout mice; Pancreas plasticity; Pancreatic beta cells; Transgenic mice

Indexed keywords

ANIMALIA; MUS; MUS MUSCULUS;

EID: 34249817566     PISSN: 27686701     EISSN: 27686698     Source Type: Journal    
DOI: 10.2741/2171     Document Type: Article

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