Chronic activation of protein kinase C in soleus muscles and other tissues of insulin-resistant type II diabetic Goto-Kakizaki (GK), obese/aged, and obese/Zucker rats: A mechanism for inhibiting glycogen synthesis

Diabetes

Volumn 45, Issue 10, 1996, Pages 1396-1404

  Avignon, Antoine ^a   Yamada, Kouji ^a   Zhou, Xiaoping ^a   Spencer, Barbara ^a   Cardona, Osvaldo ^a   Saba Siddique, Shereen ^a   Galloway, Lamar ^a   Standaert, Mary L ^a   Farese, Robert V ^a,b  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL TISSUE; ARTICLE; ENZYME ACTIVATION; GLYCOGEN SYNTHESIS; INSULIN RESISTANCE; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PRIORITY JOURNAL; RAT; SOLEUS MUSCLE;

EID: 0029742924     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diab.45.10.1396     Document Type: Article

References (47)

1. Ishizuka T, Cooper DR, Farese RV: Insulin stimulates the translocation of protein kinase C in rat adipocytes. FEBS Lett 257:397-340, 1989
2. Egan JJ, Saltis J, Wek SA, Simpson IA, Loncios C: Insulin, oxytocin, and vasopressin stimulate protein kinase C activity in adipocyte plasma membranes. Proc Natl Acad Sci USA 87:1052-1056, 1990
3. Farese RV, Standaert ML, Francois AJ, Ways K, Arnold TP, Hernandez H, Cooper DR: Effects of insulin and phorbol esters on suhcellular distribution of protein kinase C isoforms in rat adipocytes. Biochcm J 288:319-323, 1992
4. Arnold TP, Standaert ML, Hernandez H, Watson J, Mischak H, Kazanietz MG, Zhao L, Cooper DR, Farese RV: Effects of insulin and phorbol esters on MARCKS (myristoylated alanine-rich C-kinase substrate) phosphorylation (and other parameters of protein kinase C activation) in rat adipocytes, rat soleus muscle and BC3H-1 myocytes. Biochem J 295:155-164, 1993
5. Walaas SI, Horn RS, Adler A, Albert KA, Walaas O: Insulin increases membrane protein kinase C activity in rat diaphragm. FERS Lett 220:311-318, 1987
6. Ishizuka T, Cooper DR, Hernandez H, Buckley D, Standaert M, Farese RV: Effects of insulin on diacylglycerol-protcin kinase C signaling in rat diaphragm and soleus muscles and relationship to glucose transport Diabetes 39:181-190, 1990
7. Yu B, Standaert M, Arnold T, Hernandez H, Watson J, Ways K, Cooper DR, Farese RV: Effects of insulin on diacylglycerol/protein kinase C signalling and glucose transport in rat skeletal muscles in vivo and in vitro. Endocrinology 130:3345-3355, 1992
8. Yamada K, Avignon A, Standaert ML, Cooper DR, Spencer B, Farese RV: Effects of insulin on the translocation of protein kinase C-q and other protein kinase C isoforms in rat skeletal muscles. Biorhem J 308:177-180, 1995
9. Chen KS, Heydrick S, Kurowski T, Ruderman NB: Diacylglycerol-protein kinase C signalling in skeletal muscle: a possible link to insulin resistance. In Transactions of the Association of American Physicians CIV. 1991, p. 206-212
10. Cooper DR, Hernandez H, Kuo JY, Farese RV: Insulin increases the synthesis of phospholipid and diacylglycerol and protein kinase C activity in rat hepatocytes. Arch Biochem Biophys 276:486-494, 1990
11. Nivet V, Clot JP, Do XT, Barrault V, Prelot M, Durand D: Evidence that growth hormone stimulates protein kinase C activity in isolated rat hepatocytes. Metabolism 42:1291-1295, 1993
12. Cherqui G, Caron M, Wicek D, Lascols O, Capeau J, Picard J: Decreased insulin responsiveness in fat cells rendered protein kinase C-deficient by a treatment with a phorbol ester. Endocrinology 120:2192-2194, 1987
13. Tanti JF, Rochet N, Gremeaux T, Van Obberghen E, Le Marchand-Brustel Y: Insulin-stimulated glucose transport in muscle. Biochem J 258:141-146, 1989
14. Standaert ML, Buckley DJ, Ishizuka T, Hoffman JM, Coopor DR, Follet RJ, Farese RV: Protein kinase C inhibitors block insulin and PMA-stimulated hexose transport in isolated rat adipocytes and BC3H-1 myocytes. Metabolism 39:1170-1179, 1990
15. Nishimura II, Simpson IA: Staurosporine inhibits phorbol 12-myristate 13-acetate- and insulin-stimulated translocation of GLUT1 and GLUT4 glucose transporters in rat adipose cells. Biochem J 302:271-277, 1994
16. Sowell MO, Treutelaar MK, Burant OF, Buse MG: Minimal effects of phorbol esters on glucose transport and insulin sensitivity of rat skeletal muscle. Diabetes 37:499-506, 1988
17. Roach PJ, Goldman M: Modification of glycogen synthase activity in isolated rat hepatocytes by tumor-promoting phorbol esters: evidence for differential regulation of glycogen synthase and phosphorylase. Proc Natl Acad Sci USA 80:7170-7172, 1983
18. +- and phospholipid-activated protein kinase (protein kinase C). J Biol Chem 259:8743-8747, 1984
19. Bollag GE, Roth RA. Beaudoin J, Mochly-Rosen D, Koshland DE Jr.: Protein kinase C directly phosphorylates the insulin receptor in vitro and reduces its protein-tyrosine kinase activity. Proc Natl Acad Sci USA 83:5822-5824, 1986
20. Takayama S, White MF, Lauris V, Kahn OR: Phorbol esters modulate insulin receptor phosphorylation and insulin action in cultured hepatoma cells, Proc Natl Acad Sci USA 81:7797-7801, 1984
21. m of the ATP-binding site of the insulin receptor kinase from rat adipocytes. J Biol Chem 261:3869-3875, 1986
22. Saltis J, Habberfield AD, Egan JJ, Londos C, Simpson IA, Cushman SW: Role of protein kinase C in the regulation of glucose transport in the rat adipose cell. J Biol Chem 266:261-267, 1991
23. Farese RV, Standaert ML, Yu B, Hernandez H, Cooper DR: 2-Hydroxypropyl-β-cyclodextrin enhances phorbol ester effects on glucose transport and/or protein kinase C-β translocation to the plasma membrane in rat adipocytes and soleus muscles. J Biol Chem 268:19949-19955, 1993
24. 23a.Standaert MG, Bandyopadhy G, Galloway L, Farese RV: Effects of phorbol esters on insulin-induced activation of phosphatidylinositol 3-kinase, glucose transport and glycogen synthesis in rat adipocytes. FERS Lett 388:26-28, 1996
25. Guma A, Camps M, Palacin M, Testar X, Zorzano A: Protein kinase C activators selectively inhibit insulin-stimulated system A transport activity in skeletal muscle at a post-receptor level. Biochem J 268:633-639, 1990
26. Quentmeier A, Daneschmand II, Klein H, Unthan-Fechner K, Probst I: Insulin-mimetic actions of phorbol ester in cultured adult rat hepatocytes: lack of phorbol-ester-elicited inhibition of the insulin signal. Biochem J 289:549-555, 1993
27. Chen KS, Friel JC, Ruderman NB: Regulation of phosphatidylinositol 3-kinase by insulin in rat skeletal muscle. Am J Physiol 205:E736-E742, 1993
28. Kida Y, Esposito-Del Puente A, Bogardus C, Mott DM: Insulin resistance is associated with reduced fasting and insulin-stimulated glycogen synthase phosphatase activity in human skeletal muscle. J Clin Invest 85:476-481, 1990
29. Ortmeyer HK, Bodkin NL, Hansen BO: Insulin-mediated glycogen synthase activity in muscle of spontaneously insulin-resistant and diabetic rhesus monkeys. Ain J Physiol 265:R552-R558, 1993
30. Villar-Palasi C, Farese RV: Impaired skeletal muscle glycogen synthase activation by insulin in the Goto-Kakizaki (G/K) rat. Diabetologia 37:885-888, 1994
31. Farese RV, Standaert ML, Yamada K, Huang LC, Zhang C, Cooper DR, Wang Z, Yang Y, Suzuki S, Toyota T, Larner J: Insulin-induced activation of glycerol-3-phosphate acyltransferase by a chiro-inositol-containing insulin mediator is defective in adipocytes of insulin-resistant, type II diabetic, Goto-Kakizaki rats. Proc Natl Acad Sci USA 91:11040-11044, 1994
32. Bisbis S, Bailbe D, Tormo MA, Blanchot F, Derouet M, Simon J, Portha B: Insulin resistance in the GK rat: decreased receptor number but nor- mal kinase activity in liver. Am J Physiol 265:E807-E813, 1993
33. Hoffman JM, Ishizuka T, Farese RV: Interrelated effects of insulin and glucose on diacylglycerol-protein kinase C signalling in rat adipocytes and solei muscle in vitro and in vivo in diabetic rats. Endocrinology 128:2937-2948, 1991
34. Preiss J, Loomis CR, Bishop WR, Stein R, Niedel JE, Bell RM: Quantitative measurement of sn-1, 2-diacylglycerols present in platelets, hepatocytes, and ras- and sis-transformed normal rat kidney cells. J Biol Chem 261:8597-8600, 1986
35. Avignon A, Standaert ML, Yamada J, Mischak H, Spencer B, Farese RV: Insulin increases mRNA levels of protein kinase C-α and -β in rat adipocytes and protein kinase C-α, -β and -θ skeletal muscle. Biochem J 308:181-187, 1995
36. Kazanietz MG, Areces LB, Bahado A, Mischak H, Goodnight J, Mushinski JF, Blumberg PM: Characterization of ligand and substrate specificity for the calcium-dependent and calcium-independent protein kinase C isozymes. Molec Pharmacology 44:298-307, 1993
37. Baier G, Baier-Bitterlich G, Meler N, Coggeshall KM, Giampa L, Telford D, Isakov N, Altman A: Expression and biochemical characterization of human protein kinase C-θ Biochem 225:195-203, 1994
38. Kochs G, Hummel R, Meyer D, Hug H, Marme D, Sarre TF: Activation and substrate specificity of the human protein kinase C α and Ç isoenzymes. Eur J Biochem 216:597-606, 1993
39. Martiny-Baron G, Kazanietz MG, Mischak H, Blumberg PM, Kochs G, Hug H, Marme D, Schåchtele C: Selective inhibition of protein kinase C isozymes by the indolocarbazole Go 6976. J Biol Chem 268:9194-9197, 1993
40. Ishizuka T, Huffman J, Cooper DR, Watson JE, Pushkin DB, Farese RV: Glucose-induced synthesis of diacylglycerol de novo is associated with translocation (activation) of protein kinase C in rat adipocytes. FEBS Lett 249:234-238, 1989
41. Muller HK, Kellerer M, Ermel B, Muhlhofer A, Obermaier-Kusser B, Vogt B, Haring: Prevention by protein kinase C inhibitors of glucose-induced insulin-receptor tyrosine kinase resistance in rat fat cells. Diabetes 40:1440-1448, 1991
42. Ishizuka T, Yamamoto M, Kajita K, Yasuda K, Miura K, Hernandez H, Farese RV: Differential effect of aging on protein kinase C activity in rat adipocytes and soleus muscle. Metabolism 42:420-425, 1993
43. Standaert ML, Avignon A, Yamada K, Gandyopadhyay G, Farese RV: The phosphatidylinositol 3-kinase inhibitor, wortmannin, inhibits insulin-induced activation of phosphatidylcholine hydrolysis and associated protein kinase C translocation in rat adipocytes. Biochem J 313:1039-1046, 1996
44. Hoffman JM, Standaert ML, Nair GP, Farese RV: Differential effects of pertussis toxin on insulin-stimulated phosphatidylcholine hydrolysis and glycerolipid synthesis de novo: studies in BC3H-1 myocytes and rat adipocytes. Biochemistry 30:3315-3322, 1991
45. Standaert ML, Musunuru K, Yamada K, Cooper DR, Farese RV: Insulin-stimulated phosphatidylcholine hydrolysis, diacylglycerol/protein kinase C signalling, and hexose transport in pertussis toxin-treated BC3H-1 myocytes. Cell Signal 6:707-716, 1994
46. Vila M, Milligan G, Standaert ML, Farese RV: Insulin activates glycerol-3-phosphate acyltransferase (de novo phosphatidic acid synthesis) through a phospholipid-derived mediator: apparent involvement of Gia and activation of a phospholipase C. Biochemistry 29:8735-8740, 1990
47. Hughes SJ, Suzuki K, Goto Y: The role of islet secretory function in the development of diabetes in the GK Wistar rat. Diabetologia 37:863-870, 1994