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Volumn 20, Issue 3, 2007, Pages 186-199

Magnetic resonance imaging and spectroscopy of transgenic models of cancer

Author keywords

Hypoxia; Metabolism; Molecular imaging; MRI S; Receptor expression; Transgenic models of cancer

Indexed keywords

GENETIC ENGINEERING; MAGNETIC RESONANCE IMAGING; MAGNETIC RESONANCE SPECTROSCOPY; NONINVASIVE MEDICAL PROCEDURES;

EID: 34249747982     PISSN: 09523480     EISSN: 10991492     Source Type: Journal    
DOI: 10.1002/nbm.1136     Document Type: Review
Times cited : (18)

References (107)
  • 1
    • 0242487827 scopus 로고    scopus 로고
    • New magnetic resonance contrast agents as biochemical reporters
    • Meade TJ, Taylor AK, Bull SR. New magnetic resonance contrast agents as biochemical reporters. Curr Opin Neurobiol 2003; 13: 597-601
    • (2003) Curr Opin Neurobiol , vol.13 , pp. 597-601
    • Meade, T.J.1    Taylor, A.K.2    Bull, S.R.3
  • 2
    • 27644576914 scopus 로고    scopus 로고
    • Current issues in mouse genome engineering
    • Glaser S, Anastassiadis K, Stewart AF. Current issues in mouse genome engineering. Nat Genet 2005; 37: 1187-1193.
    • (2005) Nat Genet , vol.37 , pp. 1187-1193
    • Glaser, S.1    Anastassiadis, K.2    Stewart, A.F.3
  • 3
    • 25444484184 scopus 로고    scopus 로고
    • Miller G. Genetics. Mouse with human chromosome should boost Down syndrome research. Science 2005; 309: 1975.
    • Miller G. Genetics. Mouse with human chromosome should boost Down syndrome research. Science 2005; 309: 1975.
  • 4
    • 27144457779 scopus 로고    scopus 로고
    • Gene disruption/knock-in analysis of mON T3: Vector construction by employing both in vivo and in vitro recombinations
    • Ikeya M, Kawada M, Nakazawa Y, Sakuragi M, Sasai N, Ueno M, Kiyonari H, Nakao K, Sasai Y. Gene disruption/knock-in analysis of mON T3: vector construction by employing both in vivo and in vitro recombinations. Int J Dev Biol 2005; 49: 807-823.
    • (2005) Int J Dev Biol , vol.49 , pp. 807-823
    • Ikeya, M.1    Kawada, M.2    Nakazawa, Y.3    Sakuragi, M.4    Sasai, N.5    Ueno, M.6    Kiyonari, H.7    Nakao, K.8    Sasai, Y.9
  • 6
    • 33646438584 scopus 로고    scopus 로고
    • Genetically engineered murine models of prostate cancer: Insights into mechanisms of tumorigenesis and potential utility
    • Abdulkadir SA, Kim J. Genetically engineered murine models of prostate cancer: insights into mechanisms of tumorigenesis and potential utility. Future Oncol 2005; 1: 351-360.
    • (2005) Future Oncol , vol.1 , pp. 351-360
    • Abdulkadir, S.A.1    Kim, J.2
  • 7
    • 0037267313 scopus 로고    scopus 로고
    • Knockouts model the 100 best-selling drugs: Will they model the next 100?
    • Zambrowicz BP, Sands AT. Knockouts model the 100 best-selling drugs: will they model the next 100? Nat Rev Drug Discov. 2003; 2: 38-51.
    • (2003) Nat Rev Drug Discov , vol.2 , pp. 38-51
    • Zambrowicz, B.P.1    Sands, A.T.2
  • 8
    • 24044550400 scopus 로고    scopus 로고
    • Genetically engineered mouse models for drug discovery: New chemical genetic approaches
    • Heck S, Qian X, Velleca M. Genetically engineered mouse models for drug discovery: new chemical genetic approaches. Curr Drug Discov Technol 2004; 1: 13-26.
    • (2004) Curr Drug Discov Technol , vol.1 , pp. 13-26
    • Heck, S.1    Qian, X.2    Velleca, M.3
  • 10
    • 0034696260 scopus 로고    scopus 로고
    • Mouse models for breast cancer
    • Hennighausen L. Mouse models for breast cancer. Oncogene 2000; 19: 966-967.
    • (2000) Oncogene , vol.19 , pp. 966-967
    • Hennighausen, L.1
  • 11
    • 0034468231 scopus 로고    scopus 로고
    • Mouse models for breast cancer
    • Hennighausen L. Mouse models for breast cancer. Breast Cancer Res 2000; 2: 2-7.
    • (2000) Breast Cancer Res , vol.2 , pp. 2-7
    • Hennighausen, L.1
  • 12
    • 1042304249 scopus 로고    scopus 로고
    • Models of breast cancer: Is merging human and animal models the future?
    • Kim JB, O'Hare MJ, Stein R. Models of breast cancer: is merging human and animal models the future? Breast Cancer Res 2004; 6: 22-30.
    • (2004) Breast Cancer Res , vol.6 , pp. 22-30
    • Kim, J.B.1    O'Hare, M.J.2    Stein, R.3
  • 13
    • 1042269501 scopus 로고    scopus 로고
    • Models of breast cancer: Quo vadis, animal modeling?
    • Wagner KU. Models of breast cancer: quo vadis, animal modeling? Breast Cancer Res 2004; 6: 31-38.
    • (2004) Breast Cancer Res , vol.6 , pp. 31-38
    • Wagner, K.U.1
  • 15
    • 0015391488 scopus 로고
    • Characteristics of a serially transplanted mouse mammary tumor and its tissue-culture-adapted derivative
    • Rockwell SC, Kallman RF, Fajardo LF. Characteristics of a serially transplanted mouse mammary tumor and its tissue-culture-adapted derivative. J Natl Cancer Inst 1972; 49: 735-749.
    • (1972) J Natl Cancer Inst , vol.49 , pp. 735-749
    • Rockwell, S.C.1    Kallman, R.F.2    Fajardo, L.F.3
  • 16
    • 1842510704 scopus 로고    scopus 로고
    • Cardiff RD, Rosner A, Hogarth MA, Galvez JJ, Borowsky AD, Gregg JP. Validation: the new challenge for pathology. 2004; Toxicol Pathol 32(Suppl 1): 31-39.
    • Cardiff RD, Rosner A, Hogarth MA, Galvez JJ, Borowsky AD, Gregg JP. Validation: the new challenge for pathology. 2004; Toxicol Pathol 32(Suppl 1): 31-39.
  • 17
    • 4644268553 scopus 로고    scopus 로고
    • Gene transfer and expression in mammalian cell lines and transgenic animals
    • Recillas-Targa F. Gene transfer and expression in mammalian cell lines and transgenic animals. Methods Mol Biol 2004; 267: 417-433.
    • (2004) Methods Mol Biol , vol.267 , pp. 417-433
    • Recillas-Targa, F.1
  • 18
    • 0023650538 scopus 로고
    • Electroporation for the efficient transfection of mammalian cells with DNA
    • Chu G, Hayakawa H, Berg P. Electroporation for the efficient transfection of mammalian cells with DNA. Nucleic Acids Res 1987; 15: 1311-1326.
    • (1987) Nucleic Acids Res , vol.15 , pp. 1311-1326
    • Chu, G.1    Hayakawa, H.2    Berg, P.3
  • 20
    • 0007559674 scopus 로고
    • Gene transfer to human cells: Transducing phage lambda plac gene expression in GMI-gangliosidosis fibroblasts
    • Horst J, Kluge E Beyreuther K, Gerok W. Gene transfer to human cells: transducing phage lambda plac gene expression in GMI-gangliosidosis fibroblasts. Proc Natl Acad Sci USA 1975; 72: 3531-3535.
    • (1975) Proc Natl Acad Sci USA , vol.72 , pp. 3531-3535
    • Horst, J.1    Kluge, E.2    Beyreuther, K.3    Gerok, W.4
  • 21
    • 4444264909 scopus 로고    scopus 로고
    • Robust expression of transgenes in MCF-7 breast cancer cells is expression vector-dependent
    • 37 370 372 374
    • Winnard P, Jr., Mironchik Y, Raman V. Robust expression of transgenes in MCF-7 breast cancer cells is expression vector-dependent. Biotechniques 2004; 37: 370, 372, 374.
    • (2004) Biotechniques , vol.370
    • Winnard Jr., P.1    Mironchik, Y.2    Raman, V.3
  • 22
    • 0036426634 scopus 로고    scopus 로고
    • Tetracycline-controlled transcriptional regulation systems: Advances and application in transgenic animal modeling
    • Zhu Z, Zheng T, Lee CG, Homer RJ, Elias JA. Tetracycline-controlled transcriptional regulation systems: advances and application in transgenic animal modeling. Semin Cell Dev Biol 2002; 13: 121-128.
    • (2002) Semin Cell Dev Biol , vol.13 , pp. 121-128
    • Zhu, Z.1    Zheng, T.2    Lee, C.G.3    Homer, R.J.4    Elias, J.A.5
  • 23
    • 0031958982 scopus 로고    scopus 로고
    • Lac/Tet dual-inducible system functions in mammalian cell lines
    • Liu HS, Lee CH, Lee CE Su IJ, Chang TY. Lac/Tet dual-inducible system functions in mammalian cell lines. Biotechniques 1998; 24: 624-628, 630-632.
    • (1998) Biotechniques , vol.24
    • Liu, H.S.1    Lee, C.H.2    Lee, C.E.3    Su, I.J.4    Chang, T.Y.5
  • 24
    • 2642673611 scopus 로고    scopus 로고
    • Reactivation of the previously silenced cytomegalovirus major immediate-early promoter in the mouse liver: Involvement of NFkappaB
    • Loser P, Jennings GS, Strauss M, Sandig V. Reactivation of the previously silenced cytomegalovirus major immediate-early promoter in the mouse liver: involvement of NFkappaB. J Virol 1998; 72: 180-190.
    • (1998) J Virol , vol.72 , pp. 180-190
    • Loser, P.1    Jennings, G.S.2    Strauss, M.3    Sandig, V.4
  • 26
    • 23744461088 scopus 로고    scopus 로고
    • Development of a bi-cistronic baculovirus expression vector by the Rhopalosiphum padi virus 5′ internal ribosome entry site
    • Chen YJ, Chen WS, Wu TY. Development of a bi-cistronic baculovirus expression vector by the Rhopalosiphum padi virus 5′ internal ribosome entry site. Biochem Biophys Res Commun 2005; 335: 616-623.
    • (2005) Biochem Biophys Res Commun , vol.335 , pp. 616-623
    • Chen, Y.J.1    Chen, W.S.2    Wu, T.Y.3
  • 27
    • 15244351083 scopus 로고    scopus 로고
    • Coordinate dual-gene transgenesis by lentiviral vectors carrying synthetic bidirectional promoters
    • Amendola M, Venneri MA, Biffi A, Vigna E, Naldini L. Coordinate dual-gene transgenesis by lentiviral vectors carrying synthetic bidirectional promoters. Nat Biotechnol 2005; 23: 108-116.
    • (2005) Nat Biotechnol , vol.23 , pp. 108-116
    • Amendola, M.1    Venneri, M.A.2    Biffi, A.3    Vigna, E.4    Naldini, L.5
  • 29
    • 33646829448 scopus 로고    scopus 로고
    • Therapeutic potential of siRNA-mediated transcriptional gene silencing
    • Morris KV. Therapeutic potential of siRNA-mediated transcriptional gene silencing. 2006; BiotechniquesSuppl: 7-13.
    • (2006) BiotechniquesSuppl: 7-13
    • Morris, K.V.1
  • 30
    • 0037733977 scopus 로고    scopus 로고
    • Antisense technologies. Improvement through novel chemical modifications
    • Kurreck J. Antisense technologies. Improvement through novel chemical modifications. Eur J Biochem 2003; 270: 1628-1644.
    • (2003) Eur J Biochem , vol.270 , pp. 1628-1644
    • Kurreck, J.1
  • 31
    • 0036149035 scopus 로고    scopus 로고
    • Human cell knockouts
    • Bunz F. Human cell knockouts. Curr Opin Oncol 2002; 14: 73-78.
    • (2002) Curr Opin Oncol , vol.14 , pp. 73-78
    • Bunz, F.1
  • 32
    • 1842763188 scopus 로고    scopus 로고
    • New insights into the mechanism of homologous recombination in yeast
    • Aylon Y, Kupiec M. New insights into the mechanism of homologous recombination in yeast. Mutat Res 2004; 566: 231-248.
    • (2004) Mutat Res , vol.566 , pp. 231-248
    • Aylon, Y.1    Kupiec, M.2
  • 33
    • 29444431781 scopus 로고    scopus 로고
    • Nonviral vectors for cancer gene therapy: Prospects for integrating vectors and combination therapies
    • Ohlfest JR, Freese AB, Largaespada DA. Nonviral vectors for cancer gene therapy: prospects for integrating vectors and combination therapies. Curr Gene Ther 2005; 5: 629-641.
    • (2005) Curr Gene Ther , vol.5 , pp. 629-641
    • Ohlfest, J.R.1    Freese, A.B.2    Largaespada, D.A.3
  • 34
    • 0001975878 scopus 로고    scopus 로고
    • Transgenie animals: Current and alternative strategies
    • Chan AW. Transgenie animals: current and alternative strategies. Cloning 1999; 1: 25-46.
    • (1999) Cloning , vol.1 , pp. 25-46
    • Chan, A.W.1
  • 35
    • 2342480353 scopus 로고    scopus 로고
    • Production of functional transgenic mice by DNA pronuclear microinjection
    • Auerbach AB. Production of functional transgenic mice by DNA pronuclear microinjection. Acta Biochim Pol 2004; 51: 9-31.
    • (2004) Acta Biochim Pol , vol.51 , pp. 9-31
    • Auerbach, A.B.1
  • 36
    • 10444228229 scopus 로고    scopus 로고
    • Technical assessment of the first 20 years of research using mouse embryonic stem cell lines
    • Downing GJ, Battey JF, Jr, Technical assessment of the first 20 years of research using mouse embryonic stem cell lines. Stem Cells 2004; 22: 1168-1180.
    • (2004) Stem Cells , vol.22 , pp. 1168-1180
    • Downing, G.J.1    Battey Jr, J.F.2
  • 37
    • 0028222211 scopus 로고
    • LacZ transgenic mouse models: Their application in genetic toxicology
    • Gossen JA, de Leeuw WJ, Vijg J. LacZ transgenic mouse models: their application in genetic toxicology. Mutat Res 1994; 307: 451-459.
    • (1994) Mutat Res , vol.307 , pp. 451-459
    • Gossen, J.A.1    de Leeuw, W.J.2    Vijg, J.3
  • 38
    • 4644317290 scopus 로고    scopus 로고
    • Inducible gene expression in mammalian cells and mice
    • Weber W, Fussenegger M. Inducible gene expression in mammalian cells and mice. Methods Mol Biol 2004; 267: 451-466.
    • (2004) Methods Mol Biol , vol.267 , pp. 451-466
    • Weber, W.1    Fussenegger, M.2
  • 40
    • 0032560580 scopus 로고    scopus 로고
    • Green mice' and their potential usage in biological research
    • Ikawa M, Yamada S, Nakanishi T, Okabe M. 'Green mice' and their potential usage in biological research. FEBS Lett 1998; 430: 83-87.
    • (1998) FEBS Lett , vol.430 , pp. 83-87
    • Ikawa, M.1    Yamada, S.2    Nakanishi, T.3    Okabe, M.4
  • 41
    • 21444432424 scopus 로고    scopus 로고
    • Animal embryonic stem (ES) cells: Self-renewal, pluripotency, transgenesis and nuclear transfer
    • Saito S, Liu B, Yokoyama K. Animal embryonic stem (ES) cells: self-renewal, pluripotency, transgenesis and nuclear transfer. Hum Cell 2004; 17: 107-115.
    • (2004) Hum Cell , vol.17 , pp. 107-115
    • Saito, S.1    Liu, B.2    Yokoyama, K.3
  • 42
    • 27644582657 scopus 로고    scopus 로고
    • Therapeutic potential of embryonic stem cells
    • Lerou PH, Daley GQ. Therapeutic potential of embryonic stem cells. Blood Rev 2005; 19: 321-331.
    • (2005) Blood Rev , vol.19 , pp. 321-331
    • Lerou, P.H.1    Daley, G.Q.2
  • 43
    • 22244487659 scopus 로고    scopus 로고
    • Genetic regulation of stem cell origins in the mouse embryo
    • Ralston A, Rossant J. Genetic regulation of stem cell origins in the mouse embryo. Clin Genet 2005; 68: 106-112.
    • (2005) Clin Genet , vol.68 , pp. 106-112
    • Ralston, A.1    Rossant, J.2
  • 44
    • 12144255949 scopus 로고    scopus 로고
    • Derivation characteristics and perspectives for mammalian pluripotential stem cells
    • Trounson A. Derivation characteristics and perspectives for mammalian pluripotential stem cells. Reprod Fertil Dev 2005; 17: 135-141.
    • (2005) Reprod Fertil Dev , vol.17 , pp. 135-141
    • Trounson, A.1
  • 45
    • 17144407285 scopus 로고    scopus 로고
    • Making better transgenic models: Conditional, temporal, and spatial approaches
    • Ristevski S. Making better transgenic models: conditional, temporal, and spatial approaches. Mol Biotechnol 2005; 29: 153-163.
    • (2005) Mol Biotechnol , vol.29 , pp. 153-163
    • Ristevski, S.1
  • 46
    • 0031605287 scopus 로고    scopus 로고
    • Induction of a variety of preneoplasias and tumours in the mammary glands of transgenic rats
    • Davies BR, Warren JR, Schmidt G, Rudland PS. Induction of a variety of preneoplasias and tumours in the mammary glands of transgenic rats. Biochem Soc Symp 1998; 63: 167-184.
    • (1998) Biochem Soc Symp , vol.63 , pp. 167-184
    • Davies, B.R.1    Warren, J.R.2    Schmidt, G.3    Rudland, P.S.4
  • 47
    • 19944362199 scopus 로고    scopus 로고
    • A 470bp WAP-promoter fragment confers lactation independent, progesterone regulated mammary-specific gene expression in transgenic mice
    • Lipnik K, Petznek H, Renner-Muller I, Egerbacher M, Url A, Salmons B, Gunzburg WH, Hohenadl C. A 470bp WAP-promoter fragment confers lactation independent, progesterone regulated mammary-specific gene expression in transgenic mice. Transgenic Res 2005; 14: 145-158.
    • (2005) Transgenic Res , vol.14 , pp. 145-158
    • Lipnik, K.1    Petznek, H.2    Renner-Muller, I.3    Egerbacher, M.4    Url, A.5    Salmons, B.6    Gunzburg, W.H.7    Hohenadl, C.8
  • 48
    • 0031611054 scopus 로고    scopus 로고
    • Gene expression in the mammary glands of transgenic animals
    • Clark AJ. Gene expression in the mammary glands of transgenic animals. Biochem Soc Symp 1998; 63: 133-140.
    • (1998) Biochem Soc Symp , vol.63 , pp. 133-140
    • Clark, A.J.1
  • 50
    • 3142740931 scopus 로고    scopus 로고
    • Cre/loxP system for generating tissue-specific knockout mouse models
    • Kos CH. Cre/loxP system for generating tissue-specific knockout mouse models. Nutr Rev 2004; 62: 243-246.
    • (2004) Nutr Rev , vol.62 , pp. 243-246
    • Kos, C.H.1
  • 51
    • 0033008014 scopus 로고    scopus 로고
    • The Cre/loxP system and gene targeting in the kidney
    • Stricklett PK, Nelson RD, Kohan DE. The Cre/loxP system and gene targeting in the kidney. Am J Physiol 1999; 276: F651-657.
    • (1999) Am J Physiol , vol.276
    • Stricklett, P.K.1    Nelson, R.D.2    Kohan, D.E.3
  • 52
    • 0035491607 scopus 로고    scopus 로고
    • Conditional control of gene expression in the mouse
    • Lewandoski M. Conditional control of gene expression in the mouse. Nat Rev Genet 2001; 2: 743-755.
    • (2001) Nat Rev Genet , vol.2 , pp. 743-755
    • Lewandoski, M.1
  • 53
    • 32844468662 scopus 로고    scopus 로고
    • Mammalian genome targeting using site-specific recombinases
    • Garcia-Otin AL, Guillou F. Mammalian genome targeting using site-specific recombinases. Front Biosci 2006; 11: 1108-1136.
    • (2006) Front Biosci , vol.11 , pp. 1108-1136
    • Garcia-Otin, A.L.1    Guillou, F.2
  • 54
    • 0035479017 scopus 로고    scopus 로고
    • BRCA1-associated tumorigenesis: What have we learned from knockout mice?
    • Brodie SG, Deng CX. BRCA1-associated tumorigenesis: what have we learned from knockout mice? Trends Genet 2001; 17: S18-22.
    • (2001) Trends Genet , vol.17
    • Brodie, S.G.1    Deng, C.X.2
  • 55
    • 0033588843 scopus 로고    scopus 로고
    • Developmental defects and tumor predisposition in Rb mutant mice
    • Vooijs M, Berns A. Developmental defects and tumor predisposition in Rb mutant mice. Oncogene 1999; 18: 5293-5303.
    • (1999) Oncogene , vol.18 , pp. 5293-5303
    • Vooijs, M.1    Berns, A.2
  • 56
    • 0036091565 scopus 로고    scopus 로고
    • Knockout and transgenic mice of Trp53: What have we learned about p53 in breast cancer?
    • Blackburn AC, Jerry DJ. Knockout and transgenic mice of Trp53: what have we learned about p53 in breast cancer? Breast Cancer Res 2002; 4: 101-111.
    • (2002) Breast Cancer Res , vol.4 , pp. 101-111
    • Blackburn, A.C.1    Jerry, D.J.2
  • 57
    • 33744814638 scopus 로고    scopus 로고
    • Lung adenocarcinomas induced in mice by mutant EGF receptors found in human lung cancers respond to a tyrosine kinase inhibitor or to down-regulation of the receptors
    • Politi K, Zakowski MF, Fan PD, Schonfeld EA, Pao W, Varmus HE. Lung adenocarcinomas induced in mice by mutant EGF receptors found in human lung cancers respond to a tyrosine kinase inhibitor or to down-regulation of the receptors. Genes Dev 2006; 20: 1496-1510.
    • (2006) Genes Dev , vol.20 , pp. 1496-1510
    • Politi, K.1    Zakowski, M.F.2    Fan, P.D.3    Schonfeld, E.A.4    Pao, W.5    Varmus, H.E.6
  • 58
    • 22144449607 scopus 로고    scopus 로고
    • Constitutive activation of P I3 K-Akt and NF-kappaB during prostate cancer progression in autochthonous transgenic mouse model
    • Shukla S, Maclennan GT, Marengo SR, Resnick MI, Gupta S. Constitutive activation of P I3 K-Akt and NF-kappaB during prostate cancer progression in autochthonous transgenic mouse model. Prostate 2005; 64: 224-239.
    • (2005) Prostate , vol.64 , pp. 224-239
    • Shukla, S.1    Maclennan, G.T.2    Marengo, S.R.3    Resnick, M.I.4    Gupta, S.5
  • 60
    • 0346422419 scopus 로고    scopus 로고
    • High-resolution longitudinal screening with magnetic resonance imaging in a murine brain cancer model
    • Bock NA, Zadeh G, Davidson LM, Qian B, Sled JG, Guha A, Henkelman RM. High-resolution longitudinal screening with magnetic resonance imaging in a murine brain cancer model. Neoplasia 2003; 5: 546-554.
    • (2003) Neoplasia , vol.5 , pp. 546-554
    • Bock, N.A.1    Zadeh, G.2    Davidson, L.M.3    Qian, B.4    Sled, J.G.5    Guha, A.6    Henkelman, R.M.7
  • 61
    • 0036494034 scopus 로고    scopus 로고
    • Improved magnetic resonance imaging detection of prostate cancer in a transgenic mouse model
    • Song SK, Qu Z, Garabedian EM, Gordon JI, Milbrandt J, Ackerman JJ. Improved magnetic resonance imaging detection of prostate cancer in a transgenic mouse model. Cancer Res 2002; 62: 1555-1558.
    • (2002) Cancer Res , vol.62 , pp. 1555-1558
    • Song, S.K.1    Qu, Z.2    Garabedian, E.M.3    Gordon, J.I.4    Milbrandt, J.5    Ackerman, J.J.6
  • 62
    • 0037439695 scopus 로고    scopus 로고
    • Micro-magnetic resonance lymphangiography in mice using a novel dendrimer-based magnetic resonance imaging contrast agent
    • Kobayashi H, Kawamoto S, Star RA, Waldmann TA, Tagaya Y, Brechbiel MW. Micro-magnetic resonance lymphangiography in mice using a novel dendrimer-based magnetic resonance imaging contrast agent. Cancer Res 2003; 63: 271-276.
    • (2003) Cancer Res , vol.63 , pp. 271-276
    • Kobayashi, H.1    Kawamoto, S.2    Star, R.A.3    Waldmann, T.A.4    Tagaya, Y.5    Brechbiel, M.W.6
  • 63
    • 24944466815 scopus 로고    scopus 로고
    • Magnetic resonance angiography visualization of abnormal tumor vasculature in genetically engineered mice
    • Brubaker LM, Bullitt E, Yin C, Van Dyke T, Lin W. Magnetic resonance angiography visualization of abnormal tumor vasculature in genetically engineered mice. Cancer Res 2005; 65: 8218-8223.
    • (2005) Cancer Res , vol.65 , pp. 8218-8223
    • Brubaker, L.M.1    Bullitt, E.2    Yin, C.3    Van Dyke, T.4    Lin, W.5
  • 64
    • 0021111648 scopus 로고
    • Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid
    • Senger DR, Galli SJ, Dvorak AM, Perruzzi CA, Harvey VS, Dvorak HF. Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science 1983; 219: 983-985.
    • (1983) Science , vol.219 , pp. 983-985
    • Senger, D.R.1    Galli, S.J.2    Dvorak, A.M.3    Perruzzi, C.A.4    Harvey, V.S.5    Dvorak, H.F.6
  • 65
    • 0035052324 scopus 로고    scopus 로고
    • Vascular differences detected by MRI for metastatic versus nonmetastatic breast and prostate cancer xenografts
    • Bhujwalla ZM, Artemov D, Natarajan K, Ackerstaff E, Solaiyappan M. Vascular differences detected by MRI for metastatic versus nonmetastatic breast and prostate cancer xenografts. Neoplasia 2001; 3: 143-153.
    • (2001) Neoplasia , vol.3 , pp. 143-153
    • Bhujwalla, Z.M.1    Artemov, D.2    Natarajan, K.3    Ackerstaff, E.4    Solaiyappan, M.5
  • 66
    • 33745738260 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) as a target of bevacizumab in cancer: From the biology to the clinic
    • Ranieri G, Patruno R, Ruggieri E, Montemurro S, Valerio P, Ribatti D. Vascular endothelial growth factor (VEGF) as a target of bevacizumab in cancer: from the biology to the clinic. Curr Med Chem 2006; 13: 1845-1857.
    • (2006) Curr Med Chem , vol.13 , pp. 1845-1857
    • Ranieri, G.1    Patruno, R.2    Ruggieri, E.3    Montemurro, S.4    Valerio, P.5    Ribatti, D.6
  • 67
    • 27944473690 scopus 로고    scopus 로고
    • VEGF as a key mediator of angiogenesis in cancer
    • Carmeliet P. VEGF as a key mediator of angiogenesis in cancer. Oncology 2005; 69(Suppl 3): 4-10.
    • (2005) Oncology , vol.69 , Issue.SUPPL. 3 , pp. 4-10
    • Carmeliet, P.1
  • 68
    • 0037112366 scopus 로고    scopus 로고
    • Overexpression of vascular endothelial growth factor 165 drives peritumor interstitial convection and induces lymphatic drain: Magnetic resonance imaging, confocal microscopy, and histological tracking of triple-labeled albumin
    • Dafni H, Israely T, Bhujwalla ZM, Benjamin LE, Neeman M. Overexpression of vascular endothelial growth factor 165 drives peritumor interstitial convection and induces lymphatic drain: magnetic resonance imaging, confocal microscopy, and histological tracking of triple-labeled albumin. Cancer Res 2002; 62: 6731-6739.
    • (2002) Cancer Res , vol.62 , pp. 6731-6739
    • Dafni, H.1    Israely, T.2    Bhujwalla, Z.M.3    Benjamin, L.E.4    Neeman, M.5
  • 71
    • 0034062857 scopus 로고    scopus 로고
    • Weissleder R, Moore A, Mahmood U, Bhorade R, Benveniste H, Chiocca EA, Basilion JP. In vivo magnetic resonance imaging of transgene expression. 2000; Nat Med 6: 351-355.
    • Weissleder R, Moore A, Mahmood U, Bhorade R, Benveniste H, Chiocca EA, Basilion JP. In vivo magnetic resonance imaging of transgene expression. 2000; Nat Med 6: 351-355.
  • 72
    • 0037373410 scopus 로고    scopus 로고
    • MR molecular imaging of the Her-2/neu receptor in breast cancer cells using targeted iron oxide nanoparticles
    • Artemov D, Mori N, Okollie B, Bhujwalla ZM. MR molecular imaging of the Her-2/neu receptor in breast cancer cells using targeted iron oxide nanoparticles. Magn Reson Med 2003; 49: 403-408.
    • (2003) Magn Reson Med , vol.49 , pp. 403-408
    • Artemov, D.1    Mori, N.2    Okollie, B.3    Bhujwalla, Z.M.4
  • 73
    • 0038277090 scopus 로고    scopus 로고
    • Magnetic resonance molecular imaging of the HER-2/neu receptor
    • Artemov D, Mori N, Ravi R, Bhujwalla ZM. Magnetic resonance molecular imaging of the HER-2/neu receptor. Cancer Res 2003; 63: 2723-2727.
    • (2003) Cancer Res , vol.63 , pp. 2723-2727
    • Artemov, D.1    Mori, N.2    Ravi, R.3    Bhujwalla, Z.M.4
  • 74
    • 21244431682 scopus 로고    scopus 로고
    • Internal ribosome entry sites in cellular mRNAs: Mystery of their existence
    • Komar AA, Hatzoglou M. Internal ribosome entry sites in cellular mRNAs: mystery of their existence. J Biol Chem 2005; 280: 23425-23428.
    • (2005) J Biol Chem , vol.280 , pp. 23425-23428
    • Komar, A.A.1    Hatzoglou, M.2
  • 75
    • 33645772151 scopus 로고    scopus 로고
    • Quantifying exchange rates in chemical exchange saturation transfer agents using the saturation time and saturation power dependencies of the magnetization transfer effect on the magnetic resonance imaging signal (QUEST and QUESP): Ph calibration for poly-L-lysine and a starburst dendrimer
    • McMahon MT, Gilad AA, Zhou J, Sun PZ, Bulte JW, van Zijl PC. Quantifying exchange rates in chemical exchange saturation transfer agents using the saturation time and saturation power dependencies of the magnetization transfer effect on the magnetic resonance imaging signal (QUEST and QUESP): Ph calibration for poly-L-lysine and a starburst dendrimer. Magn Reson Med 2006; 55: 836-847.
    • (2006) Magn Reson Med , vol.55 , pp. 836-847
    • McMahon, M.T.1    Gilad, A.A.2    Zhou, J.3    Sun, P.Z.4    Bulte, J.W.5    van Zijl, P.C.6
  • 76
    • 0141670309 scopus 로고    scopus 로고
    • Supramolecular adducts between poly-L-arginine and [TmIIIdotp]: A route to sensitivity-enhanced magnetic resonance imaging-chemical exchange saturation transfer agents
    • Aime S, Delli Castelli D, Terreno E. Supramolecular adducts between poly-L-arginine and [TmIIIdotp]: a route to sensitivity-enhanced magnetic resonance imaging-chemical exchange saturation transfer agents. Angew Chem Int Ed Engl 2003; 42: 4527-4529.
    • (2003) Angew Chem Int Ed Engl , vol.42 , pp. 4527-4529
    • Aime, S.1    Delli Castelli, D.2    Terreno, E.3
  • 77
    • 14644420216 scopus 로고    scopus 로고
    • Ferritin as an endogenous MRI reporter for noninvasive imaging of gene expression in C6 glioma tumors
    • Cohen B, Dafni H, Meir G, Harmelin A, Neeman M. Ferritin as an endogenous MRI reporter for noninvasive imaging of gene expression in C6 glioma tumors. Neoplasia 2005; 7: 109-117.
    • (2005) Neoplasia , vol.7 , pp. 109-117
    • Cohen, B.1    Dafni, H.2    Meir, G.3    Harmelin, A.4    Neeman, M.5
  • 78
    • 0026922513 scopus 로고
    • Studies of human tumors by MRS: A review
    • Negendank W. Studies of human tumors by MRS: a review. NMR Biomed 1992; 5: 303-324.
    • (1992) NMR Biomed , vol.5 , pp. 303-324
    • Negendank, W.1
  • 79
    • 0033371680 scopus 로고    scopus 로고
    • Tumour phospholipid metabolism
    • Podo F. Tumour phospholipid metabolism. NMR Biomed 1999; 12: 413-439.
    • (1999) NMR Biomed , vol.12 , pp. 413-439
    • Podo, F.1
  • 80
    • 0035104245 scopus 로고    scopus 로고
    • Imaging biochemistry: Applications to breast cancer
    • Ronen SM, Leach MO. Imaging biochemistry: applications to breast cancer. Breast Cancer Res 2001; 3: 36-40.
    • (2001) Breast Cancer Res , vol.3 , pp. 36-40
    • Ronen, S.M.1    Leach, M.O.2
  • 81
    • 0141954157 scopus 로고    scopus 로고
    • Choline phospholipid metabolism: A target in cancer cells?
    • Ackerstaff E, Glunde K, Bhujwalla ZM. Choline phospholipid metabolism: a target in cancer cells? J Cell Biochem 2003; 90: 525-533.
    • (2003) J Cell Biochem , vol.90 , pp. 525-533
    • Ackerstaff, E.1    Glunde, K.2    Bhujwalla, Z.M.3
  • 82
    • 0035793795 scopus 로고    scopus 로고
    • Magnetic resonance detects changes in phosphocholine associated with Ras activation and inhibition in NIH 3T3 cells
    • Ronen SM, Jackson LE, Beloueche M, Leach MO. Magnetic resonance detects changes in phosphocholine associated with Ras activation and inhibition in NIH 3T3 cells. Br J Cancer 2001; 84: 691-696.
    • (2001) Br J Cancer , vol.84 , pp. 691-696
    • Ronen, S.M.1    Jackson, L.E.2    Beloueche, M.3    Leach, M.O.4
  • 83
    • 0025236381 scopus 로고
    • Altered phosphatidylcholine metabolism in C3H10T1/2 cells transfected with the Harvey-ras oncogene
    • Teegarden D, Taparowsky EJ, Kent C. Altered phosphatidylcholine metabolism in C3H10T1/2 cells transfected with the Harvey-ras oncogene. J Biol Chem 1990; 265: 6042-6047.
    • (1990) J Biol Chem , vol.265 , pp. 6042-6047
    • Teegarden, D.1    Taparowsky, E.J.2    Kent, C.3
  • 84
    • 0037203980 scopus 로고    scopus 로고
    • Regulation of choline kinase activity by Ras proteins involves Ral-GDS and PI3K
    • Ramirez de Molina A, Penalva V, Lucas L, Lacal JC. Regulation of choline kinase activity by Ras proteins involves Ral-GDS and PI3K. Oncogene 2002; 21: 937-946.
    • (2002) Oncogene , vol.21 , pp. 937-946
    • Ramirez de Molina, A.1    Penalva, V.2    Lucas, L.3    Lacal, J.C.4
  • 85
    • 0028832567 scopus 로고
    • Early increase in choline kinase activity upon induction of the H-ras oncogene in mouse fibroblast cell lines
    • Ratnam S, Kent C. Early increase in choline kinase activity upon induction of the H-ras oncogene in mouse fibroblast cell lines. Arch Biochem Biophys 1995; 323: 313-322.
    • (1995) Arch Biochem Biophys , vol.323 , pp. 313-322
    • Ratnam, S.1    Kent, C.2
  • 86
    • 0033500474 scopus 로고    scopus 로고
    • Ha-ras-transformation alters the metabolism of phosphatidylethanolamine and phosphatidylcholine in NIH 3T3 fibroblasts
    • Momchilova A, Markovska T, Pankov R. Ha-ras-transformation alters the metabolism of phosphatidylethanolamine and phosphatidylcholine in NIH 3T3 fibroblasts. Cell Biol Int 1999; 23: 603-610.
    • (1999) Cell Biol Int , vol.23 , pp. 603-610
    • Momchilova, A.1    Markovska, T.2    Pankov, R.3
  • 87
    • 0036730765 scopus 로고    scopus 로고
    • Modulation of phospholipase D by Ras proteins mediated by its effectors Ral-GDS, PI3K and Raf-1
    • Lucas L, Penalva V, Ramirez de Molina A, Del Peso L, Lacal JC. Modulation of phospholipase D by Ras proteins mediated by its effectors Ral-GDS, PI3K and Raf-1. Int J Oncol 2002; 21: 477-485.
    • (2002) Int J Oncol , vol.21 , pp. 477-485
    • Lucas, L.1    Penalva, V.2    Ramirez de Molina, A.3    Del Peso, L.4    Lacal, J.C.5
  • 88
    • 0030018131 scopus 로고    scopus 로고
    • Detection of phosphatidylcholine-specific phospholipase C in NIH-3T3 fibroblasts and their H-ras transformants: NMR and immunochemical studies
    • Podo F, Ferretti A, Knijn A, Zhang P, Ramoni C, Barletta B, Pini C, Baccarini S, Pulciani S. Detection of phosphatidylcholine-specific phospholipase C in NIH-3T3 fibroblasts and their H-ras transformants: NMR and immunochemical studies. Anticancer Res 1996; 16: 1399-1412.
    • (1996) Anticancer Res , vol.16 , pp. 1399-1412
    • Podo, F.1    Ferretti, A.2    Knijn, A.3    Zhang, P.4    Ramoni, C.5    Barletta, B.6    Pini, C.7    Baccarini, S.8    Pulciani, S.9
  • 89
    • 0032893756 scopus 로고    scopus 로고
    • Malignant transformation alters membrane choline phospholipid metabolism of human mammary epithelial cells
    • Aboagye EO, Bhujwalla ZM. Malignant transformation alters membrane choline phospholipid metabolism of human mammary epithelial cells. Cancer Res 1999; 59: 80-84.
    • (1999) Cancer Res , vol.59 , pp. 80-84
    • Aboagye, E.O.1    Bhujwalla, Z.M.2
  • 90
    • 14944385918 scopus 로고    scopus 로고
    • The C-neu mammary carcinoma in Oncomice; characterization and monitoring response to treatment with herceptin by magnetic resonance methods
    • Rodrigues LM, Stubbs M, Robinson SP, Newell B, Mansi J, Griffiths JR. The C-neu mammary carcinoma in Oncomice; characterization and monitoring response to treatment with herceptin by magnetic resonance methods. Magma 2004; 17: 260-270.
    • (2004) Magma , vol.17 , pp. 260-270
    • Rodrigues, L.M.1    Stubbs, M.2    Robinson, S.P.3    Newell, B.4    Mansi, J.5    Griffiths, J.R.6
  • 91
    • 13844281128 scopus 로고    scopus 로고
    • Loss of p53 function in colon cancer cells results in increased phosphocholine and total choline
    • Mori N, Delsite R, Natarajan K, Kulawiec M, Bhujwalla ZM, Singh KK. Loss of p53 function in colon cancer cells results in increased phosphocholine and total choline. Mol Imaging 2004; 3: 319-323.
    • (2004) Mol Imaging , vol.3 , pp. 319-323
    • Mori, N.1    Delsite, R.2    Natarajan, K.3    Kulawiec, M.4    Bhujwalla, Z.M.5    Singh, K.K.6
  • 92
    • 0032900276 scopus 로고    scopus 로고
    • Nm23-transfected MDA-MB-435 human breast carcinoma cells form tumors with altered phospholipid metabolism and pH: A 31P nuclear magnetic resonance study in vivo and in vitro
    • Bhujwalla ZM, Aboagye EO, Gillies RJ, Chacko VP, Mendola CE, Backer JM. Nm23-transfected MDA-MB-435 human breast carcinoma cells form tumors with altered phospholipid metabolism and pH: a 31P nuclear magnetic resonance study in vivo and in vitro. Magn Reson Med 1999; 41: 897-903.
    • (1999) Magn Reson Med , vol.41 , pp. 897-903
    • Bhujwalla, Z.M.1    Aboagye, E.O.2    Gillies, R.J.3    Chacko, V.P.4    Mendola, C.E.5    Backer, J.M.6
  • 93
    • 4644350944 scopus 로고    scopus 로고
    • Unlocking the potential of the human genome with RNA interference
    • Hannon GJ, Rossi JJ. Unlocking the potential of the human genome with RNA interference. Nature 2004; 431: 371-378.
    • (2004) Nature , vol.431 , pp. 371-378
    • Hannon, G.J.1    Rossi, J.J.2
  • 96
    • 0032785279 scopus 로고    scopus 로고
    • Increased choline kinase activity in 1,2-dimethylhydrazine-induced rat colon cancer
    • Nakagami K, Uchi T, Ohwada S, Koibuchi Y, Morishita Y. Increased choline kinase activity in 1,2-dimethylhydrazine-induced rat colon cancer. Jpn J Cancer Res 1999; 90: 1212-1217.
    • (1999) Jpn J Cancer Res , vol.90 , pp. 1212-1217
    • Nakagami, K.1    Uchi, T.2    Ohwada, S.3    Koibuchi, Y.4    Morishita, Y.5
  • 98
    • 3042562283 scopus 로고    scopus 로고
    • Molecular causes of the aberrant choline phospholipid metabolism in breast cancer
    • Glunde K, Jie C, Bhujwalla ZM. Molecular causes of the aberrant choline phospholipid metabolism in breast cancer. Cancer Res 2004; 64: 4270-4276.
    • (2004) Cancer Res , vol.64 , pp. 4270-4276
    • Glunde, K.1    Jie, C.2    Bhujwalla, Z.M.3
  • 99
    • 28244464886 scopus 로고    scopus 로고
    • RNA interference-mediated choline kinase suppression in breast cancer cells induces differentiation and reduces proliferation
    • Glunde K, Raman V, Mori N, Bhujwalla ZM. RNA interference-mediated choline kinase suppression in breast cancer cells induces differentiation and reduces proliferation. Cancer Res 2005; 65: 11034-11043.
    • (2005) Cancer Res , vol.65 , pp. 11034-11043
    • Glunde, K.1    Raman, V.2    Mori, N.3    Bhujwalla, Z.M.4
  • 101
    • 2542521699 scopus 로고    scopus 로고
    • Noninvasive measurements of capecitabine metabolism in bladder tumors overexpressing thymidine phosphorylase by fluorine-19 magnetic resonance spectroscopy
    • Chung YL, Troy H, Judson IR, Leek R, Leach MO, Stubbs M, Harris AL, Griffiths JR. Noninvasive measurements of capecitabine metabolism in bladder tumors overexpressing thymidine phosphorylase by fluorine-19 magnetic resonance spectroscopy. Clin Cancer Res 2004; 10: 3863-3870.
    • (2004) Clin Cancer Res , vol.10 , pp. 3863-3870
    • Chung, Y.L.1    Troy, H.2    Judson, I.R.3    Leek, R.4    Leach, M.O.5    Stubbs, M.6    Harris, A.L.7    Griffiths, J.R.8
  • 102
    • 33750569401 scopus 로고    scopus 로고
    • Raman V, Artemov D, Pathak AP, Winnard PT, Jr., McNutt S, Yudina A, Bogdanov A, Jr., Bhujwalla ZM. Characterizing vascular parameters in hypoxic regions: a combined magnetic resonance and optical imaging study of a human prostate cancer model. Cancer Res 2006; 66: 9929-9936.
    • Raman V, Artemov D, Pathak AP, Winnard PT, Jr., McNutt S, Yudina A, Bogdanov A, Jr., Bhujwalla ZM. Characterizing vascular parameters in hypoxic regions: a combined magnetic resonance and optical imaging study of a human prostate cancer model. Cancer Res 2006; 66: 9929-9936.
  • 103
    • 33747621613 scopus 로고    scopus 로고
    • Regulation of physiological responses to continuous and intermittent hypoxia by hypoxia-inducible factor 1
    • Semenza GL. Regulation of physiological responses to continuous and intermittent hypoxia by hypoxia-inducible factor 1. Exp Physiol 2006; 91: 803-806.
    • (2006) Exp Physiol , vol.91 , pp. 803-806
    • Semenza, G.L.1
  • 104
  • 105
    • 0034017489 scopus 로고    scopus 로고
    • Development of a hypoxia-responsive vector for tumor-specific gene therapy
    • Shibata T, Giaccia AJ, Brown JM. Development of a hypoxia-responsive vector for tumor-specific gene therapy. Gene Ther 2000; 7: 493-498.
    • (2000) Gene Ther , vol.7 , pp. 493-498
    • Shibata, T.1    Giaccia, A.J.2    Brown, J.M.3
  • 106
    • 33748192085 scopus 로고    scopus 로고
    • Multimodality in vivo imaging systems: Twice the power or double the trouble?
    • DOI: 10. 1146/annurev.bioeng.8.061505.095728
    • Cherry SR. Multimodality in vivo imaging systems: twice the power or double the trouble? Annu Rev Biomed Eng 2006; 8: 35-62. DOI: 10. 1146/annurev.bioeng.8.061505.095728.
    • (2006) Annu Rev Biomed Eng , vol.8 , pp. 35-62
    • Cherry, S.R.1
  • 107
    • 33645775473 scopus 로고    scopus 로고
    • Noninvasive 1H/13C magnetic resonance spectroscopic imaging of the intratumoral distribution of temozolomide
    • Kato Y, Okollie B, Artemov D. Noninvasive 1H/13C magnetic resonance spectroscopic imaging of the intratumoral distribution of temozolomide. Magn Reson Med 2006; 55: 755-761.
    • (2006) Magn Reson Med , vol.55 , pp. 755-761
    • Kato, Y.1    Okollie, B.2    Artemov, D.3


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