The very C-terminus of PRK1/PKN is essential for its activation by RhoA and downstream signaling

Cellular Signalling

Volumn 18, Issue 9, 2006, Pages 1473-1481

  Lim, Wee Guan ^a   Tan, Bee Jen ^a   Zhu, Yimin ^a   Zhou, Shufeng ^b   Armstrong, Jeffrey S ^a   Li, Qiu Tian ^a   Dong, Qihan ^c   Chan, Eli ^b   Smith, Derek ^d   Verma, Chandra ^d   Tan, Seng Lai ^e   Duan, Wei ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c UNIVERSITY OF SYDNEY   (Australia)

^d BIOINFORMATICS INSTITUTE   (Singapore)

^e ELI LILLY AND COMPANY   (United States)

Author keywords

Lisophosphatidic acid; Neurite; PKC; PKN; PKN ; PRK1; RhoA

Indexed keywords

AMINO ACID; MUTANT PROTEIN; PHOSPHATIDIC ACID; PROTEIN; PROTEIN KINASE C; PROTEIN KINASE C RELATED KINASE 1; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVATION; NERVE CELL; NEURITE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ANIMALS; CELL LINE; ENZYME ACTIVATION; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HUMANS; LYSOPHOSPHOLIPIDS; MICE; MUSCLE CONTRACTION; MUTATION; PROTEIN KINASE C; PROTEIN STRUCTURE, TERTIARY; RATS; RECOMBINANT FUSION PROTEINS; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION;

EID: 33744786565     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellsig.2005.11.009     Document Type: Article

References (42)

1. Mellor H., and Parker P.J. Biochem. J. 332 (1998) 281
2. Mukai H. J. Biochem. 133 (2003) 17
3. Gabrielli B., Wettenhall R.E., Kemp B.E., et al. FEBS Lett. 175 (1984) 219
4. Wettenhall R.E., Gabrielli B., Morrice N., et al. Pept. Res. 4 (1991) 158
5. Morrice N.A., Gabrielli B., Kemp B.E., et al. J. Biol. Chem. 269 (1994) 20040
6. Dekker L.V., Palmer R.H., and Parker P.J. Curr. Opin. Struct. Biol. 5 (1995) 396
7. Mukai H., Kitagawa M., Shibata H., et al. Biochem. Biophys. Res. Commun. 204 (1994) 348
8. Palmer R.H., Ridden J., and Parker P.J. Eur. J. Biochem. 227 (1995) 344
9. Ueno N., Oishi I., Sugiyama S., et al. Biochem. Biophys. Res. Commun. 232 (1997) 126
10. Mukai H., Mori K., Takanaga H., et al. Biochim. Biophys. Acta 1261 (1995) 296
11. Jayadev S., Linardic C.M., and Hannun Y.A. J. Biol. Chem. 269 (1994) 5757
12. Amano M., Mukai H., Ono Y., et al. Science 271 (1996) 648
13. Watanabe G., Saito Y., Madaule P., et al. Science 271 (1996) 645
14. Lu Y., and Settleman J. Genes Dev. 13 (1999) 1168
15. Gampel A., Parker P.J., and Mellor H. Curr. Biol. 9 (1999) 955
16. Marinissen M.J., Chiariello M., and Gutkind J.S. Genes Dev. 15 (2001) 535
17. Lim M.A., Yang L., Zheng Y., et al. Oncogene 23 (2004) 9348
18. Shibata H., Mukai H., Inagaki Y., et al. FEBS Lett. 385 (1996) 221
19. Maesaki R., Ihara K., Shimizu T., et al. Mol. Cell 4 (1999) 793
20. Owen D., Lowe P.N., Nietlispach D., et al. J. Biol. Chem. 278 (2003) 50578
21. Blumenstein L., and Ahmadian M.R. J. Biol. Chem. 279 (2004) 53419
22. Metzger E., Muller J.M., Ferrari S., et al. EMBO J. 22 (2003) 270
23. Zhu Y., Stolz D.B., Guo F., et al. FASEB J. 18 (2004) 1722
24. Duan W., Sun B., Li T.W., et al. Gene 256 (2000) 113
25. Flynn P., Mellor H., Palmer R., et al. J. Biol. Chem. 273 (1998) 2698
26. Lim W.G., Zhu Y., Wang C.-H., et al. Cell. Signal. 17 (2005) 1084
27. Anliker B., and Chun J. J. Biol. Chem. 279 (2004) 20555
28. Kranenburg O., Poland M., Gebbink M., et al. J. Cell Sci. 110 Pt 19 (1997) 2417
29. Li X., Saint-Cyr-Proulx E., Aktories K., et al. J. Biol. Chem. 277 (2002) 15207
30. Zhao Z.-S., and Manser E. Biochem. J. 386 (2005) 201
31. Flynn P., Mellor H., Casamassima A., et al. J. Biol. Chem. 275 (2000) 11064
32. Su L., Parissenti A.M., and Riedel H. Recept. Channels 1 (1993) 1
33. Mills G.B., and Moolenaar W.H. Nat. Rev. Cancer 3 (2003) 582
34. Dong L.Q., Landa L.R., Wick M.J., et al. Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 5089
35. Johnson L.N. ERNST Schering Res. Found. Workshop 34 (2001) 47
36. Yang J., Cron P., Good V.M., et al. Nat. Struct. Biol. 9 (2002) 940
37. Yang J., Cron P., Thompson V., et al. Mol. Cell 9 (2002) 1227
38. Taylor S.S., Radzio-Andzelm E., Madhusudan, et al. Pharmacol. Ther. 82 (1999) 133
39. Sowadski J.M., Epstein L.F., Lankiewicz L., et al. Pharmacol. Ther. 82 (1999) 157
40. Ward Y., Yap S.-F., Ravichandran V., et al. J. Cell Biol. 157 (2002) 291
41. Sahai E., and Marshall C.J. Nat. Rev. Cancer 2 (2002) 133
42. Reid T., Furuyashiki T., Ishizaki T., et al. J. Biol. Chem. 271 (1996) 13556