Design, synthesis, and biological evaluation of hybrid molecules containing α-methylene-γ-butyrolactones and α-bromoacryloyl moieties

Journal of Medicinal Chemistry

Volumn 48, Issue 24, 2005, Pages 7906-7910

  Romagnoli, Romeo ^a   Baraldi, Pier Giovanni ^a   Tabrizi, Mojgan Aghazadeh ^a   Bermejo, Jaime ^b   Estévez, Francisco ^c   Borgatti, Monica ^a   Gambari, Roberto ^a  

^a UNIVERSITY OF FERRARA   (Italy)

^b INSTITUTO DE PRODUCTOS NATURALES Y AGROBIOLOGÍA   (Spain)

^c UNIVERSITY OF LAS PALMAS DE GRAN CANARIA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

1 O ACETYLBRITANNILACTONE; ALKYLATING AGENT; ALPHA BROMOACRYLOYLAMIDE DERIVATIVE; ALPHA METHYLENE BUTYROLACTONE DERIVATIVE; ANTINEOPLASTIC AGENT; BROSTALLICIN; DISCORHABDIN G; DNA FRAGMENT; HELENALIN; METHYLENOLACTOCIN; PRIANOSIN A; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL STRAIN HL 60; CONTROLLED STUDY; DRUG ACTIVITY; DRUG DESIGN; DRUG SYNTHESIS; HUMAN; HUMAN CELL; STRUCTURE ACTIVITY RELATION;

4-BUTYROLACTONE; ACRYLAMIDES; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MICE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 28144433307     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm058012o     Document Type: Article

References (23)

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