Specific blockage of ligand-induced degradation of the Ah receptor by proteasome but not calpain inhibitors in cell culture lines from different species

Biochemical Pharmacology

Volumn 74, Issue 1, 2007, Pages 131-143

  Pollenz, Richard S ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

Aryl hydrocarbon receptor; Calpain; Proteasome; Protein degradation; TCDD; Ubiquitin

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; AROMATIC HYDROCARBON RECEPTOR; CALPAIN 3; CALPAIN 3 BLOCKING AGENT; CALPASTATIN; CALPEPTIN; CYTOCHROME P450 1A1; EPOXOMICIN; LACTACYSTIN; LIGAND; PD 150606; PROTEASOME; PROTEASOME INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DNA BINDING; DRUG EFFECT; ENZYME ACTIVITY; ENZYME INHIBITION; FLUORESCENCE; GENE CONTROL; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; IMMUNOFLUORESCENCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; WESTERN BLOTTING;

ACETYLCYSTEINE; ACRYLATES; ANIMALS; CELL LINE, TUMOR; CELL NUCLEUS; CYSTEINE PROTEINASE INHIBITORS; CYTOCHROME P-450 CYP1A1; DIPEPTIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; DRUG ANTAGONISM; DRUG COMBINATIONS; ENVIRONMENTAL POLLUTANTS; HUMANS; MICE; OLIGOPEPTIDES; RATS; RECEPTORS, ARYL HYDROCARBON; TETRACHLORODIBENZODIOXIN;

EID: 34249038892     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2007.03.021     Document Type: Article

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