Direct observation of single particle electrostatic charging by atomic force microscopy

Pharmaceutical Research

Volumn 24, Issue 6, 2007, Pages 1165-1169

  Bunker, Matthew J ^a   Davies, Martyn C ^a   James, Michael B ^b   Roberts, Clive J ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Atomic force microscopy; Electrostatic charging; Lactose; Particle interactions

Indexed keywords

LACTOSE;

ARTICLE; ATOMIC FORCE MICROSCOPY; ELECTRICITY; ELECTROCHEMISTRY; FORCE; HUMIDITY; MEASUREMENT; PRIORITY JOURNAL; SURFACE PROPERTY;

ELECTROSTATICS; MICROSCOPY, ATOMIC FORCE;

EID: 34249030619     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-006-9230-z     Document Type: Article

References (34)

1. M. J. Bunker, C. J. Roberts, and M. C. Davies. Towards screening of inhalation formulations: measuring interactions with atomic force microscopy. Expert Opin. Drug Deliv. 2:613-624 (2005).
2. C. J. Roberts. What can we learn from atomic force microscopy adhesion measurements with single drug particles? Eur. J. Pharm. Sci. 25:153-157 (2005).
3. J. K. Eve, N. Patel, S. Y. Luk, S. J. Ebbens, and C. J. Roberts. A study of single drug particle adhesion interactions using atomic force microscopy. Int. J. Pharm. 238:17-27 (2002).
4. P. M. Young, R. Price, M. J. Tobyn, M. Buttrum, and F. Dey. The influence of relative humidity on the cohesion properties of micronised drugs used in inhalation therapy. J. Pharm. Sci. 93:753-761 (2003).
5. P. R. Byron, J. Peart, and J. N. Staniforth. Aerosol electrostatics 1: properties of fine powders before and after aerosolization by dry powder inhalers. Pharm. Res. 14:698-705 (1997).
6. M. Murtomaa, V. Mellin, P. Harjunen, T. Lankinen, E. Laine, and V.-P. Lehto. Effect of particle morphology on the triboelectrification in dry powder inhalers. Int. J. Pharm. 282:107-114 (2004).
7. C. U. Yurteri, M. K. Mazumder, N. Grable, G. Ahuja, S. Trigwell, A. S. Biris, R. Sharma, and R. A. Sims. Electrostatic effects on dispersion, transport and deposition of fine pharmaceutical powders: development of an experimental method for quantitative analysis. Part. Sci. Technol. 20:59-79 (2002).
8. M. K. Mazumder, R. A. Sims, A. S. Biris, P. K. Srirama, D. Saini, C. U. Yurteri, S. Trigwell, S. De, and R. Sharma. Twenty-first century research needs in electrostatic processes applied to industry and medicine. Chem. Eng. Sci. 61:2192-2211 (2006).
9. H. Mizes, M. Ott, E. Eklund, and D. Hays. Small particle adhesion: measurement and control. Colloids Surf., A 165:11-23 (2000).
10. H. Zhou, M. Gotzinger, and W. Peukert. The influence of particle charge and roughness on particle-substrate adhesion. Powder Technol. 135-136:82-91 (2003).
11. B. Gady, R. Reifenbereger, D. S. Rimai, and L. P. DeMejo. Contact electrification and the interaction force between a micrometer-size polystyrene sphere and a graphite surface. Langmuir 13:2533-2537 (1997).
12. B. Gady, D. Schleef, R. Reifenbereger, D. S. Rimai, and L. P. Demejo. Identification of electrostatic and van der Waals interaction forces between a micrometer-size sphere and a flat substrate. Phys. Rev. B. 53:8065-8070 (1996).
13. H.-J. Butt, B. Cappella, and M. Kappl. Force measurements with the atomic force microscope: technique, interpretation and applications. Surf. Sci. Rep. 59:1-152 (2005).
14. E. Meyer, R. M. Overney, K. Dransfeld, and T. Gyalog. Nanoscience: Friction and Rheology on the Nanometer Scale. World Scientific, London, 1998.
15. T. Matsuyama and H. Yamamoto. The electrostatic force between a charged dielectric particle and a conducting plane. KONA 16:223-228 (1998).
16. J. N. Staniforth and J. E. Rees. Electrostatic charge interactions in ordered powder mixes. J. Pharm. Pharmacol. 34:69-76 (1982).
17. P. A. Carter, G. Rowley, E. J. Fletcher, and E. A. Hill. An experimental investigation of triboelectrification in cohesive and non-cohesive pharmaceutical powders. Drug Dev. Ind. Pharm. 18:1505-1526 (1992).
18. M. Murtomaa and E. Laine. Electrostatic measurements on lactose-glucose mixtures. J. Elect. 48:155-162 (2000).
19. J. Eilbeck, G. Rowley, P. A. Carter, and E. J. Fletcher. Effect of material construction of pharmaceutical processing equipment and drug delivery devices on the triboelectrification of size-fractioned lactose. Pharm. Pharmacol. Commun. 5:429-433 (1999).
20. M. Murtomaa, K. Ojanen, E. Laine, and J. Poutanen. Effect of detergent on powder triboelectrification. Eur. J. Pharm. Sci. 17:195-199 (2002).
21. G. Rowley. Quantifying electrostatic interactions in pharmaceutical solid systems. Int. J. Pharm. 227:47-55 (2001).
22. P. A. Carter, O. E. Cassidy, G. Rowley, and D. R. Merrifield. Triboelectrification of fractionated crystalline and spray-dried lactose. Pharm. Pharmacol. Commun. 4:111-115 (1998).
23. H.-K. Chan. Dry powder aerosol drug delivery-opportunities for colloid and surface scientists. Colloids Surf., A 284-285:50-55 (2006).
24. P. Kulvanich and P. J. Stewart. Influence of relative humidity on the adhesive properties of a model interactive system. J. Pharm. Pharmacol. 40:453-458 (1988).
25. X. M. Zeng, G. P. Martin, and C. Marriott. Particulate Interactions in Dry Powder Formulations for Inhalation. Taylor & Francis, London, 2001.
26. T. Nguyen and S. Nieh. The role of water vapour in the charge elimination process for flowing powders. J. Elect. 22:213-227 (1989).
27. J. Eilbeck, G. Rowley, P. A. Carter, and E. J. Fletcher. Effect of contamination of pharmaceutical equipment on powder triboelectrification. Int. J. Pharm. 195:7-11 (2000).
28. J. L. Hutter and J. Bechhoefer. Calibration of atomic-force microscope tips. Rev. Sci. Instrum. 64:1868-1873 (1993).
29. F. K. Dey, J. A. S. Cleaver, and P. A. Zhdan. Atomic force microscopy study of adsorbed moisture on lactose particles. Adv. Powder Technol. 11:401-413 (2000).
30. L. B. Schein and W. S. Czarnecki. Electrostatic proximity force, toner adhesion, and atomic force microscopy of insulating particles. J. Elect. 63:699-704 (2005).
31. N. Sun and J. Y. Walz. A model for calculating electrostatic interactions between colloidal particles of arbitary surface topology. J. Colloid Interface Sci. 234:90-105 (2000).
32. P. Girard. Electrostatic force microscopy: principles and some applications to semiconductors. Nanotechnology 12:485-490 (2001).
33. D. R. Lide (ed.). CRC Handbook of Chemistry and Physics, 74th ed., CRC, Boca Raton, 1993.
34. J. Lowell. Contact electrification of silica and soda glass. J. Phys. D: Appl. Phys. 23:1082-1091 (1990).