The protease domain of procollagen C-proteinase (BMP1) lacks substrate selectivity, which is conferred by non-proteolytic domains

Biological Chemistry

Volumn 388, Issue 5, 2007, Pages 513-521

  Wermter, Carsten ^a   Höwel, Markus ^a   Hintze, Vera ^a,b   Bombosch, Bettina ^a   Aufenvenne, Karin ^a,c   Yiallouros, Irene ^a   Stöcker, Walter ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

^c UNIVERSITY HOSPITAL MÜNSTER   (Germany)

Author keywords

Astacin; BMP1; CUB EGF modules; Metalloprotease; Metzincin; Procollagen I

Indexed keywords

COLLAGEN TYPE 1; COLLAGEN TYPE 4; EPIDERMAL GROWTH FACTOR; FIBRONECTIN; MATRIX PROTEIN; PROCOLLAGEN C PROTEINASE; PROTEINASE; RECOMBINANT ENZYME; THROMBOSPONDIN 1;

ARTICLE; CARBOXY TERMINAL SEQUENCE; COMPARATIVE STUDY; ENZYME SPECIFICITY; ENZYME SUBSTRATE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FUNCTION;

AMINO ACID MOTIFS; ANIMALS; BONE MORPHOGENETIC PROTEINS; CELL LINE; COLLAGEN TYPE VII; CYSTEINE; DISULFIDES; DNA, COMPLEMENTARY; DROSOPHILA MELANOGASTER; ESCHERICHIA COLI; GENE EXPRESSION; GLUTAMIC ACID; HUMANS; INCLUSION BODIES; MASS SPECTROMETRY; METALLOENDOPEPTIDASES; MUTATION; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY;

ECHINOIDEA;

EID: 34249022942     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/BC.2007.054     Document Type: Article

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