Synthesis and biological activity of new melatonin dimeric derivatives

Bioorganic and Medicinal Chemistry

Volumn 15, Issue 13, 2007, Pages 4643-4650

  Di Giacomo, Barbara ^a   Bedini, Annalida ^a   Spadoni, Gilberto ^a   Tarzia, Giorgio ^a   Fraschini, Franco ^b   Pannacci, Marilou ^b   Lucini, Valeria ^b  

^a UNIVERSITY OF URBINO   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

Author keywords

Biligands; Melatonin; Melatonin dimers; MLT receptors

Indexed keywords

10 [3 (2 ACETAMIDOETHYL) 5 METHOXY 1H INDOLE 2 CARBONYLOXY]DECYL 3 (2 ACETAMIDOETHYL) 5 METHOXY 1H INDOLE 2 CARBOXYLIC ACID; 12 [3 (2 ACETAMIDOETHYL) 5 METHOXY 1H INDOLE 2 CARBONYLOXY]DODECYL 3 (2 ACETAMIDOETHYL) 5 METHOXY 1H INDOLE 2 CARBOXYLIC ACID; 3 (2 ACETAMIDOETHYL) 5 METHOXY 1H INDOLE 2 CARBOXYLIC ACID; 3 (2 ACETAMIDOETHYL) 5 METHOXY 1H INDOLE 2 CARBOXYLIC ACID METHYL ESTER; 3 [3 (2 ACETAMIDOETHYL) 5 METHOXY 1H INDOLE 2 CARBOXY]PROPYL 3 (2 ACETAMIDOETHYL) 5 METHOXY 1H INDOLE 2 CARBOXYLIC ACID; 5 [3 (2 ACETAMIDOETHYL) 5 METHOXY 1H INDOLE 2 CARBONYLOXY]PENTYL 3 (2 ACETAMIDOETHYL) 5 METHOXY 1H INDOLE 2 CARBOXYLIC ACID; 5 METHOXY 3 (2 NITROVINYL) 1H INDOLE 2 CARBOXYLIC ACID METHYL ESTER; 7 [3 (2 ACETAMIDOETHYL) 5 METHOXY 1H INDOLE 2 CARBONYLOXY]HEPTYL 3 (2 ACETAMIDOETHYL) 5 METHOXY 1H INDOLE 2 CARBOXYLIC ACID; 8 [3 (2 ACETAMIDOETHYL) 5 METHOXY 1H INDOLE 2 CARBONYLOXY]OCTYL 3 (2 ACETAMIDOETHYL) 5 METHOXY 1H INDOLE 2 CARBOXYLIC ACID; 9 (BENZOYLOXY)NONYL 3 (2 ACETAMIDOETHYL) 5 METHOXY 1H INDOLE 2 CARBOXYLIC ACID; 9 [3 (2 ACETAMIDOETHYL) 5 METHOXY 1H INDOLE 2 CARBONYLOXY]NONYL 3 (2 ACETAMIDOETHYL) 5 METHOXY 1H INDOLE 2 CARBOXYLIC ACID; ALKYL GROUP; CARBOXYALKYL; MELATONIN; MELATONIN 1 RECEPTOR; MELATONIN 2 RECEPTOR; N 1,N 10 BIS[2 (5 METHOXY 1H INDOL 3 YL)ETHYL]DECANEDIAMIDE; N 1,N 7 BIS[2 (5 METHOXY 1H INDOL 3 YL)ETHYL]HEPTANEDIAMIDE; PENTYL 3 (2 ACETAMIDOETHYL) 5 METHOXY 1H INDOLE 2 CARBOXYLIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BIOLOGICAL ACTIVITY; DRUG ACTIVITY; DRUG BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; IN VIVO CULTURE; NONHUMAN; RAT;

3T3 CELLS; ANIMALS; FIBROBLASTS; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HUMANS; INDICATORS AND REAGENTS; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MELATONIN; MICE; RATS; RECEPTOR, MELATONIN, MT1; RECEPTOR, MELATONIN, MT2;

RATTUS;

EID: 34248670685     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.03.080     Document Type: Article

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