Conditional depletion of KasA, a key enzyme of mycolic acid biosynthesis, leads to mycobacterial cell lysis

Journal of Bacteriology

Volumn 187, Issue 22, 2005, Pages 7596-7606

  Bhatt, Apoorva ^a   Kremer, Laurent ^b   Dai, Annie Z ^a   Sacchettini, James C ^c   Jacobs Jr , William R ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b UNIVERSITÉ DE MONTPELLIER   (France)

^c TEXAS A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 OXOACYL ACYL CARRIER PROTEIN SYNTHASE; ACYL CARRIER PROTEIN; ALPHA MYCOLIC ACID; ALPHA' MYCOLIC ACID; EPOXYMYCOLIC ACID; FATTY ACID SYNTHASE; FATTY ACID SYNTHASE II; MYCOLIC ACID; PROTEIN ACPM; PROTEIN INHA; PROTEIN KASA; PROTEIN KASB; UNCLASSIFIED DRUG;

ALLELE; ARTICLE; BACTERIAL CELL; BACTERIAL GENE; BACTERIAL MUTATION; BACTERIAL STRAIN; BACTERIUM MUTANT; CONDITIONAL EXPRESSION SPECIALIZED TRANSDUCTION ESSENTIALITY TEST; CYTOLYSIS; GENE EXPRESSION; GENETIC PROCEDURES; GENETIC TRANSDUCTION; IMAGE ANALYSIS; KASA GENE; KASB GENE; MYCOBACTERIUM SMEGMATIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; SCANNING ELECTRON MICROSCOPY;

3-OXOACYL-(ACYL-CARRIER-PROTEIN) SYNTHASE; BACTERIAL PROTEINS; BACTERIOLYSIS; FATTY ACID SYNTHETASE COMPLEX; GENES, BACTERIAL; GENES, ESSENTIAL; MICROSCOPY, ELECTRON, SCANNING; MUTATION; MYCOBACTERIUM SMEGMATIS; MYCOLIC ACIDS; OXIDOREDUCTASES; TRANSDUCTION, GENETIC;

BACTERIA (MICROORGANISMS); MYCOBACTERIUM SMEGMATIS;

EID: 27744492218     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.187.22.7596-7606.2005     Document Type: Article

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