DNA distortion and multimerization: Novel functions of the glutamine-rich domain of GAGA factor

Journal of Molecular Biology

Volumn 285, Issue 2, 1999, Pages 515-525

  Wilkins, R Chris ^b   Lis, John T ^a  

^a Department of Obstetrics Gynecology   (United States)

^b NONE

Author keywords

GAF; Heat shock genes; Hsp70; Melting; Q domain

Indexed keywords

DEOXYRIBONUCLEASE I; GLUTAMINE; HEAT SHOCK PROTEIN 70;

ARTICLE; BINDING AFFINITY; CHROMATIN STRUCTURE; DROSOPHILA MELANOGASTER; GENETIC TRANSCRIPTION; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION REGULATION;

DROSOPHILA MELANOGASTER; MELANOGASTER;

EID: 0033556090     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1998.2356     Document Type: Article

References (37)

1. Andersson L.-O., Borg H., Mikaelsson M. Molecular weight estimations of proteins by electrophoresis in polyacrylamide gels of graded porosity. FEBS Letters. 20:1972;199-201.
2. Bardwell V. J., Treisman R. The POZ domain: a conserved protein-protein interaction motif. Genes Dev. 8:1994;1664-1677.
3. Benyajati C., Mueller L., Xu N., Pappano M., Gao J., Mosammaparast M., Conklin D., Granok H., Craig C., Elgin S. C. R. Multiple isoforms of GAGA factor, a critical component of chromatin structure. Nucl. Acids Res. 25:1997;3345-3353.
4. Biggin M. D., Tjian R. Transcription factors that activate the ultrabithorax promoter in developmentally staged extracts. Cell. 53:1988;699-711.
5. Chen W., Zollman S., Couderac J., Laski F. A. The BTB domain of bric a brac mediates dimerization in vitro. Mol. Cell. Biol. 15:1995;3424-3429.
6. Clos J., Westwood J. T., Becker P. B., Wilson S., Lambert K., Wu C. Molecular cloning and expression of a hexameric Drosophila heat shock factor subject to negative regulation. Cell. 63:1990;1085-1097.
7. Courey R., Tjian R. Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motif. Cell. 55:1988;887-898.
8. Croston G. E., Kerrigan L. A., Lira L. M., Marshak D. R., Kadonaga J. T. Sequence specific antirepression of histone H1 mediated inhibition of basal RNA polymerase II transcription. Science. 251:1991;643-649.
9. Dhordain P., Albagli O., Lin R. J., Ansieau S., Quief S., Leutz A., Kerckaert J.-P., Evans R. M., Leprince D. Corepressor SMRT binds the BTB/POZ repressing domain of the LAZ3/BCL6 oncoprotein. Proc. Natl Acad. Sci. USA. 94:1997;10762-10767.
10. Emili A., Greenblatt J., Ingles C. J. Species-specific interaction of the glutamine-rich activation domains of Sp1 with the TATA box-binding protein. Mol. Cell. Biol. 14:1994;1582-1593.
11. Giardina C., Perez-Ribs M., Lis J. T. Promoter melting and TFIID complexes on Drosphila genes in vivo. Genes Dev. 6:1992;2190-2200.
12. Gill G., Pascal E., Tseng Z. H., Tjian R. A glutamine-rich hydrophobic patch in transcription factor Sp1 contacts the dTAF110 component of the Drosophila TFIID complex and mediates transcriptional activation. Proc. Natl Acad. Sci. USA. 91:1994;192-196.
13. Gilmour D. S., Elgin S. C. R. Drosophila nuclear proteins bind to regions of alternating C and T residues in gene promoters. Science. 245:1989;1487-1490.
14. Granok H., Leibovitch B. A., Shaffer C. D., Elgin S. C. R. Ga-ga over GAGA factor. Curr. Biol. 5:1995;238-241.
15. Hseih M., Tintut Y., Gralla J. D. Functional roles for the glutamines within the glutamine-rich region of the transcription factor σ54. J. Biol. Chem. 269:1994;373-378.
16. Kaplan J., Calame K. The ZiN/POZ domain of ZF5 is required for both transcriptional activation and repression. Nucl. Acid Res. 25:1997;1108-1116.
17. Kerrigan L. A., Croston G. E., Lira L. M., Kadonaga J. T. Sequence specific transcriptional antirepression of the Drosophila Kruppel gene by the GAGA factor. J. Biol. Chem. 266:1990;574-582.
18. Lee H.-S., Kraus K. W., Wolfner M. F., Lis J. T. DNA sequence requirements for generating paused polymerase at the start of hsp70. Genes Dev. 6:1992;284-295.
19. Mason P. B. J., Lis J. T. Cooperative and competitive protein interactions at the Hsp70 promoter. J. Biol. Chem. 272:1997;33227-33233.
20. Nardelli J., Gibson T., Vesque C., Charnay P. Base sequence discrimination by zinc-finger DNA-binding domains. Nature. 349:1991;175-178.
21. O'Brien T., Wilkins R. C., Giardina C., Lis J. T. Distribution of GAGA protein on Drosophila genes in vivo. Genes Dev. 9:1995;1098-1110.
22. Omichinski J. G., Pedone P. V., Felsenfeld G., Gronenborn A. M., Clore G. M. The solution structure of a specific GAGA factor-DNA complex reveals a modular binding mode. Nature Struct. Biol. 4:1997;122-132.
23. Pascal E., Tjian R. Different activation domains of Sp1 govern formation of multimers and mediate transcriptional synergism. Genes Dev. 5:1991;1646-1656.
24. Pedone P. V., Ghirlando R., Clore G. M., Gronenborn A. M., Felsenfeld G., Omichinski J. G. The single Cys2-His2 zinc finger domain of the GAGA protein flanked by basic residues is sufficient for high-affinity specific DNA binding. Proc. Natl Acad. Sci. USA. 93:1996;2822-2826.
25. Perutz M. Polar zippers: their role in human disease. Protein Sci. 3:1994;1629-1637.
26. Pinto M., Lobe C. G. Products of the grg (Groucho-related gene) family can dimerize through the amino-terminal Q domain. J. Biol. Chem. 271:1996;33026-33031.
27. Shopland L., Hirayoshi K., Fernandes M., Lis J. T. HSF access to heat shock elements in vivo depends critically on promoter architecture defined by GAGA factor, TFIID, and RNA polymerase II binding sites. Genes Dev. 9:1995;2756-2769.
28. Smoly'Yaninova T. I., Bruskov V. I., Kashparova E. V. Model study of DNA-protein interactions I. The influence of amino-carboxylate and amide groups of amino-acids on DNA thermostability and conformation. Molekul. Biol. (Moscow). 19:1985;992-1000.
29. Soeller W. C., Kornberg T. In vitro transcription of the Drosophila engrailed gene. Genes Dev. 2:1987;68-81.
30. Stott K., Blackburn J. M., Butler P. J. G., Perutz M. Incorporation of glutamine repeats makes protein oligomerize: implications for neurodegenerative diseases. Proc. Natl Acad. Sci. USA. 92:1995;6509-6513.
31. Strom A.-C., Forsberg M., Lillhager P., Westin G. The transcription factors SP1 and Oct-1 interact physically to regulate human U2 snRNA gene expression. Nucl. Acids Res. 24:1996;1981-1986.
32. Tsukiyama T., Wu C. Purification and properties of an ATP-dependant nucleosome remodeling factor. Cell. 83:1995;1011-1020.
33. Tsukiyama T., Becker P., Wu C. ATP-dependent nucleosome disruption at a heat-shock promoter mediated by binding of GAGA transcription factor. Nature. 367:1994;525-532.
34. Weber J. A., Gilmour D. S. Genomic footprinting of the hsp70 and histone H3 promoters in Drosophila embryos reveals novel protein-DNA interactions. Nucl. Acids Res. 23:1995;3327-3334.
35. Wilkins R. C., Lis J. T. Dynamics of potentiation and activation: GAGA factor and its role in heat shock gene regulation. Nucl. Acids Res. 25:1997;3963-3968.
36. Wilkins R. C., Lis J. T. GAGA factor binding to DNA via a single trinucleotide sequence element. Nucl. Acids Res. 26:1998;2672-2678.
37. Zollman S., Godt D., Prive G. G., Couderc J., Laski F. A. The BTB domain, found primarily in zinc finger proteins, defines an evolutionarily conserved family that includes several developmentally regulated genes in Drosophila. Proc. Natl Acad. Sci. USA. 91:1994;10717-10721.