Swapping the substrate specificities of the neuropeptidases neurolysin and thimet oligopeptidase

Journal of Biological Chemistry

Volumn 282, Issue 13, 2007, Pages 9722-9732

  Lim, Eun Jeong ^a   Sampath, Sowmya ^a   Coll Rodriguez, Jerry ^a   Schmidt, Jack ^a   Ray, Kallol ^a,b   Rodgers, David W ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING SITES; BIOACTIVITY; METABOLISM; OLIGOMERS; PEPTIDES; SUBSTRATES;

BIOACTIVE PEPTIDES; NEUROPEPTIDASES NEUROLYSIN; NEUROTENSINS; THIMET OLIGOPEPTIDASE;

ENZYMES;

ARGININE; ASPARTIC ACID; DOPAMINE RECEPTOR STIMULATING AGENT; GLUTAMINE; HISTIDINE; METALLOPROTEINASE; METHIONINE; NEUROLYSIN; NEUROPEPTIDE; NEUROTENSIN; THIMET OLIGOPEPTIDASE;

ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; DOPAMINERGIC ACTIVITY; ENZYME BINDING; ENZYME SPECIFICITY; ENZYME SUBSTRATE; HYDROLYSIS; NOCICEPTION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN METABOLISM; PROTEIN STRUCTURE; SURFACE CHARGE; THERMOREGULATION; AMINO ACID SUBSTITUTION; CHEMISTRY; COMPARATIVE STUDY; GENETICS; HUMAN; METABOLISM; X RAY CRYSTALLOGRAPHY;

AMINO ACID SUBSTITUTION; CRYSTALLOGRAPHY, X-RAY; HUMANS; METALLOENDOPEPTIDASES; SUBSTRATE SPECIFICITY;

EID: 34248175828     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M609897200     Document Type: Article

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