Selection of anthrax toxin protective antigen variants that discriminate between the cellular receptors TEM8 and CMG2 and achieve targeting of tumor cells

Journal of Biological Chemistry

Volumn 282, Issue 13, 2007, Pages 9834-9845

  Chen, Kuang Hua ^a   Liu, Shihui ^a   Bankston, Laurie A ^b   Liddington, Robert C ^b   Leppla, Stephen H ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRAX TOXINS; PROTECTIVE ANTIGEN (PA) PROTEIN; TUMOR ANGIOGENESIS;

ANGIOGRAPHY; CELLS; COMPLEXATION; DISEASES; MUTAGENESIS; TOXIC MATERIALS; TUMORS;

ANTIGENS;

ANTHRAX TOXIN; BACTERIAL ANTIGEN; CAPILLARY MORPHOGENESIS GENE 2 PRODUCT; CELL RECEPTOR; MUTANT PROTEIN; TUMOR ENDOTHELIAL MARKER 8; UNCLASSIFIED DRUG; ANTHRAX TOXIN RECEPTOR 1, HUMAN; ANTXR2 PROTEIN, HUMAN; BACTERIAL TOXIN; CELL SURFACE RECEPTOR; MEMBRANE PROTEIN; TUMOR PROTEIN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL KILLING; CHO CELL; CONTROLLED STUDY; CYTOTOXICITY; DRUG TARGETING; FEMALE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; NONHUMAN; PHAGE DISPLAY; PRIORITY JOURNAL; TARGET CELL; TUMOR CELL; AMINO ACID SEQUENCE; ANIMAL; ANTIGENIC VARIATION; CELL LINE; CHEMISTRY; CRICETULUS; GENETICS; HAMSTER; HELA CELL; METABOLISM; MOLECULAR GENETICS; PROTEIN TERTIARY STRUCTURE; TUMOR CELL LINE;

BACILLUS ANTHRACIS; CRICETULUS GRISEUS; EUKARYOTA;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; ANTIGENIC VARIATION; ANTIGENS, BACTERIAL; BACTERIAL TOXINS; CELL LINE; CELL LINE, TUMOR; CHO CELLS; CRICETINAE; CRICETULUS; HELA CELLS; HUMANS; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; NEOPLASM PROTEINS; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CELL SURFACE;

EID: 34248163999     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M611142200     Document Type: Article

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