Protein tyrosine nitration and poly(ADP-ribose) polymerase activation in N-methyl-N-nitro-N-nitrosoguanidine-treated thymocytes: Implication for cytotoxicity

Toxicology Letters

Volumn 170, Issue 3, 2007, Pages 203-213

  Bai, Péter ^a,b   Hegedus, Csaba ^a,b   Erdélyi, Katalin ^a,b   Szabó, Éva ^a   Bakondi, Edina ^a,b   Gergely, Szabolcs ^a   Szabó, Csaba ^c   Virág, László ^a,b  

^a UNIVERSITY OF DEBRECEN   (Hungary)

^b INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^c University of Medicine and Dentistry of New Jersey   (United States)

Author keywords

1 Methyl 3 nitro 1 nitrosoguanidine; Apoptosis; Necrosis; Nitric oxide; Peroxynitrite; Poly(ADP ribose) polymerase

Indexed keywords

ACETYLCYSTEINE; CATALASE; DNA; GLUTATHIONE; METHYLNITRONITROSOGUANIDINE; N (5,6 DIHYDRO 6 OXO 2 PHENANTHRIDINYL) 2 DIMETHYLAMINOACETAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; PEROXYNITRITE; PROTEIN TYROSINE PHOSPHATASE; SCAVENGER; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; AQUEOUS SOLUTION; ARTICLE; CATALYST; CELL DEATH; CELL PROTECTION; COMET ASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DECOMPOSITION; DNA ALKYLATION; DNA STRAND BREAKAGE; ENZYME ACTIVITY; MALE; MOUSE; NITRATION; NONHUMAN; PRIORITY JOURNAL; THYMOCYTE;

ALKYLATING AGENTS; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CASPASES; CELL DEATH; CELL SURVIVAL; COMET ASSAY; DNA DAMAGE; DNA FRAGMENTATION; FLUORESCENT ANTIBODY TECHNIQUE; MALE; METHYLNITRONITROSOGUANIDINE; MICE; MICE, INBRED C57BL; MITOCHONDRIA; NITRATES; NITRIC OXIDE; PEROXYNITROUS ACID; POLY(ADP-RIBOSE) POLYMERASES; SUPEROXIDES; T-LYMPHOCYTES; TYROSINE;

EID: 34248137349     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2007.03.007     Document Type: Article

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