Structural effects on the phosphorylation of 3-substituted 1-β-d-ribofuranosyl-1,2,4-triazoles by human adenosine kinase

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 11, 2007, Pages 3203-3207

  Kumarapperuma, Sidath C ^a   Sun, Yanjie ^b   Jeselnik, Marjan ^a   Chung, Kiwon ^a   Parker, William B ^b   Jonsson, Colleen B ^b   Arterburn, Jeffrey B ^a  

^a NEW MEXICO STATE UNIVERSITY   (United States)

^b SOUTHERN RESEARCH INSTITUTE   (United States)

Author keywords

Adenosine kinase; Antiviral; Bioisostere; Ribavirin; Triazole

Indexed keywords

1 BETA DEXTRO RIBOFURANOSYL 1,2,4 TRIAZOLE DERIVATIVE; ADENOSINE KINASE; PHOSPHATE; RIBAVIRIN; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; DRUG BINDING; DRUG IDENTIFICATION; DRUG SYNTHESIS; ENZYME PHOSPHORYLATION; HUMAN; HYDROGEN BOND; LIPOPHILICITY;

ADENOSINE KINASE; ANTIVIRAL AGENTS; COMPUTERS; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PHOSPHORYLATION; RIBAVIRIN; STEREOISOMERISM; TRIAZOLES;

EID: 34247893961     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.03.018     Document Type: Article

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