Diminished lifespan and acute stress-induced death in DNA-PKcs-deficient mice with limiting telomeres

Oncogene

Volumn 26, Issue 20, 2007, Pages 2815-2821

  Wong, K K ^a   Maser, R S ^a   Sahin, E ^a   Bailey, S T ^b   Xia, H ^a   Ji, H ^a   McNamara, K ^a   Naylor, M ^c   Bronson, R T ^c   Ghosh, S ^b   Welsh, R ^d   DePinho, R A ^a,c  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

Aging; Cytokines; DNAPKcs; Stress; Telomerase; Telomere

Indexed keywords

CYTOKINE; DNA; POLYINOSINIC POLYCYTIDYLIC ACID; TUMOR NECROSIS FACTOR ALPHA;

ACUTE STRESS; AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHRONIC STRESS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA DAMAGE; DNA REPAIR; GENE INTERACTION; HEREDITY; IMMUNE RESPONSE; IMMUNOSTIMULATION; INNATE IMMUNITY; LIFESPAN; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; TELOMERE; VIRUS INFECTION;

ANIMALS; CROSSES, GENETIC; DNA-ACTIVATED PROTEIN KINASE; DNA-BINDING PROTEINS; HEPATITIS, ANIMAL; INTERLEUKIN-1BETA; INTERLEUKIN-6; LIVER; LONGEVITY; MICE; MICE, TRANSGENIC; MURINE HEPATITIS VIRUS; NUCLEAR PROTEINS; RNA; STRESS; TELOMERASE; TELOMERE; TUMOR NECROSIS FACTOR-ALPHA;

MUS;

EID: 34247887533     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1210099     Document Type: Article

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