Recent developments in superporous hydrogels

Journal of Pharmacy and Pharmacology

Volumn 59, Issue 3, 2007, Pages 317-327

  Omidian, Hossein ^a   Park, Kinam ^b   Rocca, Jose G ^a  

^a Kos Pharmaceuticals Inc   (United States)

^b PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; POLYMER; DRUG CARRIER;

DRUG ABSORPTION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RETENTION; HUMAN; HYDROGEL; INTESTINE ABSORPTION; POROSITY; REVIEW; SUPERPOROUS HYDROGEL; TABLET FORMULATION; ANIMAL; CHEMISTRY; DELAYED RELEASE FORMULATION; PARTICLE SIZE;

ANIMALS; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; HYDROGELS; PARTICLE SIZE; POROSITY;

EID: 34247643910     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp.59.3.0001     Document Type: Review

References (48)

1. Agyilirah, G. A., Green, M., DuCret, R., Banker, G. S. (1991) Evaluation of the gastric retention properties of a cross-linked polymer coated tablet versus those of a non-disintegrating tablet. Int. J. Pharm. 75: 241
2. Baek, N., Park, K., Park, J. H., Bae, Y. H. (2001) Control of the swelling rate of superporous hydrogels. J. Bioactive Compatible Polymers 16: 47-57
3. Chen, J., Park, K. (2000a) Synthesis of fast-swelling, superporous sucrose hydrogels. Carbohydr. Polymers 41: 259-268
4. Chen, J., Park, K. (2000b) Synthesis and characterization of superporous hydrogel composites. J. Control. Release 65: 73-82
5. Chen, J., Park, H., Park, K. (1999) Synthesis of superporous hydrogels: hydrogels with fast swelling and superabsorbent properties. J. Biomed. Materials Res. 44: 53-62
6. Chen, J., Blevins, W. E., Park, H., Park K. (2000) Gastric retention properties of superporous hydrogel composites. J. Control. Release 64: 39-51(13)
7. Dorkoosh, F. A., Brussee, J., Verhoef, J. C., Borchard, G., Rafiee-Tehrani, M., Junginger, H. E. (2000) Preparation and NMR characterization of superporous hydrogels (SPH) and SPH composites. Polymer 41: 8213-8220
8. Dorkoosh, F. A., Verhoef, J. C., Borchard, G., Rafiee-Tehrani, M., Junginger, H. E. (2001) Development and characterization of a novel peroral peptide drug delivery system. J. Controll. Release 71: 307-318
9. Dorkoosh, F. A., Verhoef, J. C., Borchard, G., Rafiee-Tehrani, M., Verheijden, J. H. M., Junginger, H. E. (2002a) Intestinal absorption of human insulin in pigs using delivery systems based on superporous hydrogel polymers. Int. J. Pharm. 247: 47-55
10. Dorkoosh, F. A., Verhoef, J. C., Verheijden, J. H. M., Rafiee-Tehrani, M., Borchard, G., Junginger, H. E. (2002b) Peroral absorption of octreotide in pigs formulated in delivery systems on the basis of superporous hydrogel polymers. Pharm. Res. 19: 1532-1536
11. Dorkoosh, F. A., Setyaningsih, D., Borchard, G., Rafiee-Tehrani, M., Verhoef, J. C., Junginger, H. E. (2002c) Effects of superporous hydrogels on paracellular drug permeability and cytotoxicity studies in Caco-2 cell monolayers. Int. J. Pharm. 241: 35-45
12. Dorkoosh, F.A., Borchard, G., Rafiee-Tehrani, M., Verhoef, J. C., Junginger, H. E. (2002d) Evaluation of superporous hydrogel (SPH) and SPH composite in porcine intestine ex-vivo: assessment of drug transport, morphology effect, and mechanical fixation to intestinal wall. Eur. J. Pharm. Biopharm. 53: 161-166
13. Dorkoosh, F. A., Verhoef, J. C., Ambagts, M. H., Rafiee-Tehrani, M., Borchard, G., Junginger, H. E. (2002e) Peroral delivery systems based on superporous hydrogel polymers: release characteristics for the peptide drugs buserelin, octreotide and insulin. Eur. J. Pharm. Sci. 15: 433-439
14. Dorkoosh, F. A., Verhoef, J. C., Borchard, G., Rafiee-Tehrani, M., Verheijden, J. H., Junginger, H. E. (2002f) Intestinal absorption of human insulin in pigs using delivery systems based on superporous hydrogel polymers. Int. J. Pharm. 247: 47-55
15. Dorkoosh, F. A., Verhoef, J. C., Verheijden, J. H., Rafiee-Tehrani, M., Borchard, G., Junginger, H. E. (2002g) Peroral absorption of octreotide in pigs formulated in delivery systems on the basis of superporous hydrogel polymers. Pharm. Res. 19: 1532-1536
16. Dorkoosh, F. A., Stokkel, M. P., Blok, D., Borchard, G., Rafiee-Tehrani, M., Verhoef, J. C., Junginger, H. E. (2004a) Feasibility study on the retention o f superporous hydrogel composite polymer in the intestinal tract of man using scintigraphy. J. Control. Release 99: 199-206
17. Dorkoosh, F. A., Broekhuizen, C. A., Borchard, G., Rafiee-Tehrani, M., Verhoef, J. C., Junginger, H. E. (2004b) Transport of octreotide and evaluation of mechanism of opening the paracellular tight junctions using superporous hydrogel polymers in Caco-2 cell monolayers. J. Pharm. Sci. 93: 743-752
18. Gemeinhart, R. A., Chen, J., Park, H., Park, K. (2000a) pH-sensitivity of fast responsive superporous hydrogels. J. Biomaterials Sci., Polymer Edition 11: 1371-1380
19. Gemeinhart, R. A., Park, H., Park, K. (2000b) Pore structure of superporous hydrogels. Polymers Adv. Technol. 11: 617-625
20. Gemeinhart, R. A., Park, H., Park, K. (2001) Effect of compression on fast swelling of poly (AAm-co-AAc) superporous hydrogels. J. Biomed. Mat. Res. 55: 54-62
21. Han, W., Omidian, H., Rocca, J. G. (2003) In vivo and in vitro studies on novel gastroretentive superporous hydrogel (SPH) platforms. American Association of Pharmaceutical Scientists (AAPS), Salt Lake City, Utah, USA, October 26-30, 2003, Published in AAPS Pharmsci., 5: W4119
22. st Annual Meeting of the Controlled Release Society (CRS), Honolulu, Hawaii, USA, June 12-16
23. Hilton, A. K., Deasy, P. B. (1992) In vitro and in vivo evaluation of an oral sustained-release floating dosage form of amoxicillin trihydrate. Int. J. Pharm. 86: 79-88
24. Huh, K. M., Baek, N., Park, K. (2005) Enhanced swelling rate of poly (ethylene glycol)-grafted superporous hydrogels. J. Bioactive Compatible Polymers 20: 231-243
25. Ichikawa, M., Watanabe, S., Miyake, Y. (1991a) A new multiple-unit oral floating dosage system. I: preparation and in vitro evaluation of floating and sustained-release characteristics. J. Pharm. Sci. 80: 1062-1066
26. Ichikawa, M., Kato, T., Kawahara, M., Watanabe, S., Kayano, M. (1991b) A new multiple-unit oral floating dosage system. II: in vivo evaluation of floating and sustained-release characteristics with p-aminobenzoic acid and isosorbide dinitrate as model drugs. J. Pharm. Sci. 80: 1153-1156
27. Jayakrishnan, A., Mohanty, M., Mandalam, R., Rao, V. R. K., Gupta, A. K., Joseph, S. (1994) Endovascular emoblization using hydrogel microspheres. J. Mat. Sci. Mat. Med. 5: 723-727
28. Kim, D., Park, K. (2004) Swelling and mechanical properties of superporous hydrogels of poly (AAm-co-AAc) polyethyleneimine interpenetrating polymer networks. Polymer 45: 189-196
29. Kim, D., Seo, K., Park, K. (2004) Polymer composition and acidification effects on the swelling and mechanical properties of poly (AAm-co-AAc) superporous hydrogels. J. Biomaterials Sci., Polymer Edition 15: 189-199
30. Omidian, H., Park, K. (2002) Experimental design in the synthesis of polyacrylamide superporous hydrogels. J. Bioactive Compatible Polymers 17: 433-450
31. Omidian, H., Rocca, J. G. (2006) Formation of strong superporous hydrogels. US Patent 7056957
32. Omidian, H., Zohuriaan-Mehr, M. J., Kabiri, K., Shah, K. (2004) Polymer chemistry attractiveness: synthesis and swelling studies of gluttonous hydrogels in the advanced academic laboratory. J. Polymer Materials 21: 281-292
33. Omidian, H., Rocca, J. G., Park, K. (2005a) Advances in superporous hydrogels. J. Control. Release 102: 3-12
34. Omidian, H., Qiu, Y., Yang, S., Kim, D., Park, H., Park, K. (2005b) Hydrogels having enhanced elasticity and mechanical strength properties. US Patent 6960617
35. Omidian, H., Rocca, J. G., Park, K. (2006) Elastic superporous hydrogel hybrid of polyacrylamide and sodium alginate. Macromol. Biosci. 6: 703-710
36. Park, K. (2002) Superporous hydrogels for pharmaceutical and other applications. Drug Deliv. Technol. 2: 38-44
37. Park, K., Chen, J., Park, H. (2001) Hydrogel composites and superporous hydrogel composites having fast swelling, high mechanical strength, and superabsorbent properties. US Patent No 6271278
38. Park, H., Park, K., Kim, D. (2005) Preparation and swelling behavior of chitosan-based superporous hydrogels for gastric retention application. J. Biomed. Mat. Res. Part A 76A: 144-150
39. Polnok, A., Verhoef, J. C., Borchard, G., Sarisuta, N., Junginger, H. E. (2004) In vitro evaluation of intestinal absorption of desmopressin using drug-delivery systems based on superporous hydrogels. Int. J. Pharm. 269: 303-310
40. Rocca, J. G., Omidian, H., Shah, K. (2003) Progresses in gastroretentive drug delivery systems. PharmaTech 152-156
41. Rocca, J. G., Shah, K., Omidian, H. (2004) Superporous hydrogels containing solid and semi-solid carriers. Gattefosse Tech. Bull. Nov 2004
42. Rocca, J. G., Omidian, H., Shah, K. (2005) Gastric retention technologies: commercial status of gastric retention technologies. Drug Deliv. Technol. 5: 40-46
43. Swanson, D. R., Barclay, B. L., Wong, P. S., Theeuwes, F. (1987) Nifedipine gastrointestinal therapeutic system. Am. J. Med. 83: 3-9
44. Tellez, C., Benson, A. B., Lyster, M. T., Talamonti, M., Shaw, J., Braun, M. A., Nemcek, A. A., Vogelzang, R. L. (1998) Phase II trial of chemoembolization for the treatment of metastatic colorectal carcinoma to the liver and review of the literature. Cancer 82: 1250-1259
45. Thangamathesvaran, P. M., Omidian, H., Rathinavelu, A., Rocca, J. G. (2004) Metal-chelated superporous hydrogels. Part 2: structural and calorimetric characterization. AAPS Pharmaceutics and Drug Delivery Conference, Philadelphia, USA, June
46. Townsend, R., Rocca, J. G., Omidian, H. (2005) Safety and toxicity studies of a novel gastroretentive platform administered orally in a swine emesis model. The 32nd Annual Meeting of the Controlled Release Society (CRS); Miami, Florida, USA, June 18-22
47. Yang, S., Park, K., Rocca, J. G. (2004a) Semi-interpenetrating polymer network superporous hydrogels based on poly (3-sulfopropyl acrylate, potassium salt) and poly (vinyl alcohol): synthesis and characterization. J. Bioactive Compatible Polymers 19: 81-100
48. Yang, S., Fu, Y., Jeong, S. H., Park, K. (2004b) Application of poly (AAc) superporous hydrogel microparticles as a superdisintegrant in fast-disintegrating tablets. J. Pharm. Pharmacol. 56: 429-436