Evaluation of superporous hydrogel (SPH) and SPH composite in porcine intestine ex-vivo: Assessment of drug transport, morphology effect, and mechanical fixation to intestinal wall

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 53, Issue 2, 2002, Pages 161-166

  Dorkoosh, F A ^a   Borchard, G ^a   Rafiee Tehrani, M ^a   Verhoef, J C ^a   Junginger, H E ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Intestinal drug transport; Mechanical fixation; Morphology of porcine intestine; Peptide drug; Superporous hydrogel composite; Superporous hydrogels

Indexed keywords

BENZOYLARGININE ETHYL ESTER; FLUORESCEIN ISOTHIOCYANATE; POLYMER;

ANIMAL TISSUE; ARTICLE; DRUG DOSAGE FORM; DRUG TRANSPORT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROGEL; INTESTINE ABSORPTION; INTESTINE EPITHELIUM; MORPHOLOGY; NONHUMAN; PRESSURE; SWINE; TIGHT JUNCTION; TRANSPORT KINETICS;

ANIMALS; BIOLOGICAL TRANSPORT; BIOMECHANICS; CENTRIFUGATION; DRUG CARRIERS; DRUG EVALUATION, PRECLINICAL; HYDROGEL; INTESTINAL MUCOSA; JEJUNUM; POROSITY; SWINE;

EID: 0036185185     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0939-6411(01)00222-3     Document Type: Article

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