Coptidis rhizoma extract protects against cytokine-induced death of pancreatic β-cells through suppression of NF-κB activation

Experimental and Molecular Medicine

Volumn 39, Issue 2, 2007, Pages 149-159

  Kim, Eun Kyung ^a   Kwon, Kang Beom ^b   Han, Mi Jeong ^a   Song, Mi Young ^a   Lee, Ji Hyun ^a   Lv, Na ^a   Ka, Sun O ^a   Yeom, Seung Ryong ^b   Kwon, Young Dal ^b   Ryu, Do Gon ^b   Kim, Kang San ^b   Park, Jin Woo ^a   Park, Raekil ^c   Park, Byung Hyun ^a  

^a Chonbuk National University   (South Korea)

^b Wonkwang University   (South Korea)

^c Wonkwang University   (South Korea)

Author keywords

Cell death; Coptidis rhizoma extract; Cytokines; Drugs, Chinese herbal; Insulin secreting cells; NF kappa B; Nitric oxide

Indexed keywords

COPTIDIS RHIZOMA EXTRACT; GAMMA INTERFERON; GLUCOSE; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INSULIN; INTERLEUKIN 1BETA; NITRIC OXIDE; PLANT EXTRACT; SYNAPTOTAGMIN I; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL DEATH; CELL DESTRUCTION; CELL PROTECTION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; GENE EXPRESSION; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RELEASE; MALE; NONHUMAN; PANCREAS ISLET BETA CELL; PROTEIN DEGRADATION; RAT;

RATTUS;

EID: 34247594974     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.1038/emm.2007.17     Document Type: Article

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