Biochemical anti-opioid action of NPFF2 receptors in rat spinal cord

Neuroscience Research

Volumn 58, Issue 1, 2007, Pages 91-94

  Gouardères, Christine ^a   Zajac, Jean Marie ^a  

^a INSTITUT DE PHARMACOLOGIE ET DE BIOLOGIE STRUCTURALE   (France)

Author keywords

35S GTP S; Anti opioid; NPFF; Opioid; Receptor

Indexed keywords

ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); NEUROPEPTIDE FF; OPIATE AGONIST;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BINDING ASSAY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG EFFECT; DRUG POTENCY; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD;

ANALGESICS, OPIOID; ANIMALS; BINDING, COMPETITIVE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENKEPHALIN, ALA(2)-MEPHE(4)-GLY(5)-; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); NEURONS; RADIOLIGAND ASSAY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, NEUROPEPTIDE; SPINAL CORD;

EID: 34247592417     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neures.2007.01.013     Document Type: Article

References (25)

1. Ballet S., Conrath M., Fischer J., Kaneko T., Hamon M., and Cesselin F. Expression and G-protein coupling of mu-opioid receptors in the spinal cord and dorsal root ganglia of polyarthritic rats. Neuropeptides 37 (2003) 211-219
2. Elshourbagy N.A., Ames R.S., Fitzgerald L.R., Foley J.J., Chambers J.K., Szekeres P.G., Evans N.A., Schmidt D.B., Buckley P.T., Dytko G.M., Murdock P.R., Milligan G., Groarke D.A., Tan K.B., Shabon U., Nuthulaganti P., Wang D.Y., Wilson S., Bergsma D.J., and Sarau H.M. Receptor for the pain modulatory neuropeptides FF and AF is an orphan G protein-coupled receptor. J. Biol. Chem. 275 (2000) 25965-25971
3. Gilman A.G. G proteins: transducers of receptor-generated signals. Annu. Rev. Biochem. 56 (1987) 615-649
4. Gouarderes C., Puget A., and Zajac J.M. Detailed distribution of neuropeptide FF receptors (NPFF1 and NPFF2) in the rat, mouse, octodon, rabbit, guinea pig, and marmoset monkey brains: a comparative autoradiographic study. Synapse 51 (2004) 249-269
5. Gouarderes C., Quelven I., Mollereau C., Mazarguil H., Rice S.Q., and Zajac J.M. Quantitative autoradiographic distribution of NPFF1 neuropeptide FF receptor in the rat brain and comparison with NPFF2 receptor by using [125I]YVP and [(125I]EYF as selective radioligands. Neuroscience 115 (2002) 349-361
6. Gouarderes C., Roumy M., Advokat C., Jhamandas K., and Zajac J.M. Dual localization of neuropeptide FF receptors in the rat dorsal horn. Synapse 35 (2000) 45-52
7. Gouardères C., Tafani J.A., and Zajac J.M. Affinity of neuropeptide FF analogs to opioid receptors in the rat spinal cord. Peptides 19 (1998) 727-730
8. 35S]GTPgammaS autoradiography: optimization for high sensitivity. Eur. J. Pharmacol. 422 (2001) 1-13
9. 35S]GTPgammaS binding assay: approaches and applications in pharmacology. Life Sci. 74 (2003) 489-508
10. Hinuma S., Shintani Y., Fukusumi S., Iijima N., Matsumoto Y., Hosoya M., Fujii R., Watanabe T., Kikuchi K., Terao Y., Yano T., Yamamoto T., Kawamata Y., Habata Y., Asada M., Kitada C., Kurokawa T., Onda H., Nishimura O., Tanaka M., Ibata Y., and Fujino M. New neuropeptides containing carboxy-terminal RFamide and their receptor in mammals. Nat. Cell Biol. 2 (2000) 703-708
11. Kersante F., Mollereau C., Zajac J.M., and Roumy M. Anti-opioid activities of NPFF1 receptors in a SH-SY5Y model. Peptides 27 (2006) 980-989
12. Kotani M., Mollereau C., Detheux M., Le Poul E., Brezillon S., Vakili J., Mazarguil H., Vassart G., Zajac J.M., and Parmentier M. Functional characterization of a human receptor for neuropeptide FF and related peptides. Br. J. Pharmacol. 133 (2001) 138-144
13. Mollereau C., Mazarguil H., Zajac J.M., and Roumy M. Neuropeptide FF (NPFF) analogs functionally antagonize opioid activities in NPFF2 receptor-transfected SH-SY5Y neuroblastoma cells. Mol. Pharmacol. 67 (2005) 965-975
14. Mollereau C., Roumy M., and Zajac J.M. Opioid-modulating peptides: mechanisms of action. Curr. Top. Med. Chem. 5 (2005) 341-355
15. Oldham W.M., and Hamm H.E. Structural basis of function in heterotrimeric G proteins. Q. Rev. Biophys. (2006) 117-166
16. Panula P., Kalso E., Nieminen M., Kontinen V.K., Brandt A., and Pertovaara A. Neuropeptide FF and modulation of pain. Brain Res. 848 (1999) 191-196
17. Roumy M., Garnier M., and Zajac J.-M. Neuropeptide FF receptors 1 and 2 exert an anti-opioid activity in acutely dissociated rat dorsal raphe and periventricular hypothalamic neurons. Neurosci. Lett. 348 (2003) 159-162
18. Roumy M., and Zajac J. Neuropeptide FF selectively attenuates the effects of nociceptin on acutely dissociated neurons of the rat dorsal raphe nucleus. Brain Res. 845 (1999) 208-214
19. Roumy M., and Zajac J.M. Neuropeptide FF, pain and analgesia. Eur. J. Pharmacol. 345 (1998) 1-11
20. Roussin A., Serre F., Gouarderes C., Mazarguil H., Roumy M., Mollereau C., and Zajac J.M. Anti-analgesia of a selective NPFF2 agonist depends on opioid activity. Biochem. Biophys. Res. Commun. 336 (2005) 197-203
21. 35S]GTP gamma S binding in mMOR-CHO cells and rat thalamus. J. Pharmacol. Exp. Ther. 285 (1998) 496-505
22. 35S]thio]-triphosphate binding. Proc. Natl. Acad. Sci. U.S.A. 92 (1995) 7242-7246
23. 35S]thio)triphosphate binding to membranes from human neuroblastoma SH-SY5Y cells. Mol. Pharmacol. 47 (1995) 848-854
24. Zajac J.M., Gully D., and Maffrand J.P. [3H]-SR 27897B: a selective probe for autoradiographic labelling of CCK-A receptors in the brain. J. Recept. Signal Transduct. Res. 16 (1996) 93-113
25. Zajac J.M., and Mollereau C. RFamide peptides. Introduction. Peptides 27 (2006) 941-942