Potent and selective agonists of α-melanotropin (αMSH) action at human melanocortin receptor 5; linear analogs of α-melanotropin

Peptides

Volumn 28, Issue 5, 2007, Pages 1020-1028

  Bednarek, Maria A ^a   MacNeil, Tanya ^a   Tang, Rui ^a   Fong, Tung M ^a   Cabello, M Angeles ^b   Maroto, Marta ^b   Teran, Ana ^b  

^a MERCK RESEARCH LABORATORIES   (United States)

^b Medical affairs Merck sharp and Dohme ltd   (Spain)

Author keywords

Melanotropin; MSH; Agonist; Binding affinity; cAMP accumulation assay; Melanocortin peptide; Melanocortin receptor 5; NDP MSH

Indexed keywords

ALPHA INTERMEDIN; MELANOCORTIN 5 RECEPTOR;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DRUG POTENCY; DRUG PROTEIN BINDING; IC 50; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN STRUCTURE; SOLID PHASE SYNTHESIS; SOLUBILITY;

ALPHA-MSH; AMINO ACID SEQUENCE; ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; CYCLIC AMP; HUMANS; MOLECULAR STRUCTURE; PROTEIN BINDING; RECEPTORS, CORTICOTROPIN; STRUCTURE-ACTIVITY RELATIONSHIP;

RODENTIA;

EID: 34247549317     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2007.02.011     Document Type: Article

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