Melanocortin receptors: New opportunities in drug discovery

Expert Opinion on Therapeutic Patents

Volumn 11, Issue 1, 2001, Pages 61-76

  Wikberg, J E S ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

Agouti; Agouti related peptide; Feeding control; Melanocortin receptors; Melanocyte stimulating hormone; Organic compounds; Peptide agonists; Peptide antagonists; Physiological mechanisms; Pro opio melanocortins; Therapeutic utility

Indexed keywords

AGOUTI PROTEIN; AGOUTI RELATED PROTEIN; ALPHA INTERMEDIN; AMINO ACID; ARGININE; BETA ENDORPHIN; CORTICOTROPIN DERIVATIVE; CORTICOTROPIN RECEPTOR; CYCLIC AMP; G PROTEIN COUPLED RECEPTOR; GLUCAGON LIKE PEPTIDE 2; HORMONE RECEPTOR BLOCKING AGENT; HORMONE RECEPTOR STIMULATING AGENT; INOSITOL PHOSPHATE; INTERMEDIN DERIVATIVE; MELANIN CONCENTRATING HORMONE; MELANOCORTIN; MELANOCORTIN 1 RECEPTOR; MELANOCORTIN 2 RECEPTOR; MELANOCORTIN 3 RECEPTOR; MELANOCORTIN 4 RECEPTOR; MELANOCORTIN 5 RECEPTOR; MELANOCORTIN RECEPTOR; NEUROPEPTIDE Y; OREXIN; OXYTOCIN; PHENYLALANINE; PROOPIOMELANOCORTIN; STAT PROTEIN; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANOREXIA; CONTROLLED STUDY; DRUG ABUSE; DRUG ACTIVITY; DRUG RESEARCH; FEMALE; HORMONAL REGULATION; HORMONE ACTION; HUMAN; INFLAMMATORY DISEASE; MALE; MOLECULAR CLONING; MOUSE; NONHUMAN; OBESITY; PATENT; RAT; REVIEW; RHESUS MONKEY; SEXUAL DYSFUNCTION; SIGNAL TRANSDUCTION;

EID: 0035178980     PISSN: 13543776     EISSN: None     Source Type: Journal    
DOI: 10.1517/13543776.11.1.61     Document Type: Review

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35. 2 with bulky aromatic amino acids at position 7 show high antagonist potency and melanocortin receptors
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