-
1
-
-
0141819138
-
The protein C pathway
-
Esmon CT. The protein C pathway. Chest. 2003;124:26S-32S.
-
(2003)
Chest
, vol.124
-
-
Esmon, C.T.1
-
2
-
-
3943060904
-
Thrombomodulin-protein C-EPCR system integrated to regulate coagulation and inflammation
-
Wouwer MV, Collen D, Conway EM. Thrombomodulin-protein C-EPCR system integrated to regulate coagulation and inflammation. Arterioscler Thromb Vasc Biol. 2004;24:1374-1383.
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 1374-1383
-
-
Wouwer, M.V.1
Collen, D.2
Conway, E.M.3
-
3
-
-
25144462156
-
Overexpressing endothelial cell protein C receptor alters the hemostatic balance and protects mice from endotoxin
-
Li W, Zheng X, Gu J, et al. Overexpressing endothelial cell protein C receptor alters the hemostatic balance and protects mice from endotoxin. J Thromb Haemost. 2005;3:1351-1359.
-
(2005)
J Thromb Haemost
, vol.3
, pp. 1351-1359
-
-
Li, W.1
Zheng, X.2
Gu, J.3
-
5
-
-
0037079736
-
Plasma levels of endothelial protein C respond to anticoagulant treatment
-
Stearns-Kurosawa DJ, Swindle K, D'Angelo A, et al. Plasma levels of endothelial protein C respond to anticoagulant treatment. Blood. 2002;99:526-530.
-
(2002)
Blood
, vol.99
, pp. 526-530
-
-
Stearns-Kurosawa, D.J.1
Swindle, K.2
D'Angelo, A.3
-
6
-
-
32344451648
-
Effect of various genetic polymorphisms on the incidence and outcome of severe sepsis
-
Sipahi T, Pocan H, Akar N. Effect of various genetic polymorphisms on the incidence and outcome of severe sepsis. Clin Appl Thromb Hemost. 2006;12:47-54.
-
(2006)
Clin Appl Thromb Hemost
, vol.12
, pp. 47-54
-
-
Sipahi, T.1
Pocan, H.2
Akar, N.3
-
7
-
-
21644438082
-
International pediatric sepsis consensus conference: Definitions for sepsis and organ dysfunction in pediatrics
-
Goldstein B, Giroir B, Randolph A. International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics. Pediatr Crit Care Med. 2005;6:2-8.
-
(2005)
Pediatr Crit Care Med
, vol.6
, pp. 2-8
-
-
Goldstein, B.1
Giroir, B.2
Randolph, A.3
-
9
-
-
0034050886
-
Mechanisms by which soluble endothelial protein C receptor modulates protein C and activated protein C function
-
Liaw PCY, Neuenschwander PF, Smirnov MD, Esmon CT. Mechanisms by which soluble endothelial protein C receptor modulates protein C and activated protein C function. J Biol Chem. 2000;275;5447-5452.
-
(2000)
J Biol Chem
, vol.275
, pp. 5447-5452
-
-
Liaw, P.C.Y.1
Neuenschwander, P.F.2
Smirnov, M.D.3
Esmon, C.T.4
-
10
-
-
0030036189
-
The endothelial protein C receptor
-
Regan LM, Stearns-Kurosawa DJ, Kurosawa S, Mollica J, Fukudome K, Esmon CT. The endothelial protein C receptor. J Biol Chem. 2000;271;17499- 17503.
-
(2000)
J Biol Chem
, vol.271
, pp. 17499-17503
-
-
Regan, L.M.1
Stearns-Kurosawa, D.J.2
Kurosawa, S.3
Mollica, J.4
Fukudome, K.5
Esmon, C.T.6
-
11
-
-
0043240071
-
Expression and function of the endothelial protein C receptor in human neutrophils
-
Sturn DH, Kaneider NC, Feistritzer C, Djanani A, Fukudome K, Wiedermann CJ. Expression and function of the endothelial protein C receptor in human neutrophils. Blood. 2003;102:1499-1505.
-
(2003)
Blood
, vol.102
, pp. 1499-1505
-
-
Sturn, D.H.1
Kaneider, N.C.2
Feistritzer, C.3
Djanani, A.4
Fukudome, K.5
Wiedermann, C.J.6
-
12
-
-
0037044806
-
Distruption of the endothelial cell protein C receptor gene in mice causes placental thrombosis and early embryonic lethality
-
Gu JM, Crawley JT, Ferrell G, et al. Distruption of the endothelial cell protein C receptor gene in mice causes placental thrombosis and early embryonic lethality. J Biol Chem. 2002;277:43335-43343.
-
(2002)
J Biol Chem
, vol.277
, pp. 43335-43343
-
-
Gu, J.M.1
Crawley, J.T.2
Ferrell, G.3
-
13
-
-
0034774749
-
A 23 bp insertion in the endothelial protein C receptor (EPCR) gene impairs EPCR function
-
Biguzzi E, Merati G, Liaw PC, et al. A 23 bp insertion in the endothelial protein C receptor (EPCR) gene impairs EPCR function. Thromb Haemost. 2001;86:945-948.
-
(2001)
Thromb Haemost
, vol.86
, pp. 945-948
-
-
Biguzzi, E.1
Merati, G.2
Liaw, P.C.3
-
14
-
-
0034145311
-
The endothelial cell protein C receptor aids in host defense against Escherichia coli sepsis
-
Taylor FB, Stearns-Kurosawa DJ, Kurosawa S, et al. The endothelial cell protein C receptor aids in host defense against Escherichia coli sepsis. Blood. 2000;95:1680-1686.
-
(2000)
Blood
, vol.95
, pp. 1680-1686
-
-
Taylor, F.B.1
Stearns-Kurosawa, D.J.2
Kurosawa, S.3
-
15
-
-
0035826096
-
Efficacy and safety of recombinant human activated protein C for severe sepsis
-
Bernard GR, Vincent JL, Laterre PF, et al. Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med. 2001; 344:699-709.
-
(2001)
N Engl J Med
, vol.344
, pp. 699-709
-
-
Bernard, G.R.1
Vincent, J.L.2
Laterre, P.F.3
-
16
-
-
0037588986
-
The role of the endothelium in severe sepsis and multiple organ dysfunction syndome
-
Aird WC. The role of the endothelium in severe sepsis and multiple organ dysfunction syndome. Blood. 2003;101:3765-3777.
-
(2003)
Blood
, vol.101
, pp. 3765-3777
-
-
Aird, W.C.1
-
17
-
-
10244250329
-
Patients with severe sepsis vary markedly in their ability to generate activated protein C
-
Liaw PCY, Esmon CT, Kahnamoui K, et al. Patients with severe sepsis vary markedly in their ability to generate activated protein C. Blood. 2004;104:3958-3964.
-
(2004)
Blood
, vol.104
, pp. 3958-3964
-
-
Liaw, P.C.Y.1
Esmon, C.T.2
Kahnamoui, K.3
-
18
-
-
0034548822
-
An open-label study of the role of adjuvant hemostatic support with protein C replacement therapy in purpura fulminans-associated meningococcemia
-
White B, Livingstone W, Murphy C, Hodgson A, Rafferty M, Smith OP. An open-label study of the role of adjuvant hemostatic support with protein C replacement therapy in purpura fulminans-associated meningococcemia. Blood. 2000;96:3719-3724.
-
(2000)
Blood
, vol.96
, pp. 3719-3724
-
-
White, B.1
Livingstone, W.2
Murphy, C.3
Hodgson, A.4
Rafferty, M.5
Smith, O.P.6
-
19
-
-
0036913809
-
Endothelial cell protein C receptor (EPCR) gene exon III, 23 bp insertion mutation in the Turkish pediatric thrombotic patients
-
Akar N, G̈okdemir R, Ozel D, Akar E. Endothelial cell protein C receptor (EPCR) gene exon III, 23 bp insertion mutation in the Turkish pediatric thrombotic patients. Thromb Haemost. 2002;88:1068-1069.
-
(2002)
Thromb Haemost
, vol.88
, pp. 1068-1069
-
-
Akar, N.1
G̈okdemir, R.2
Ozel, D.3
Akar, E.4
-
20
-
-
33646864520
-
ENHANCE: Results of a global open-label trial of drotrecogin alfa (activated) in children with sepsis
-
Goldstein B, Nadel S, Peters M, et al. ENHANCE: results of a global open-label trial of drotrecogin alfa (activated) in children with sepsis. Pediatr Crit Care Med. 2006;7:200-211.
-
(2006)
Pediatr Crit Care Med
, vol.7
, pp. 200-211
-
-
Goldstein, B.1
Nadel, S.2
Peters, M.3
-
21
-
-
0141567620
-
Recombinant human activated protein C (rhAPC; drotrecogin alfa [activated]) has minimal effect on markers of coagulation, fibrinolysis, and inflammation in acute human endotoxemia
-
Derhaschnig U, Reiter R, Kn̈oble P, Baumgartner M, Keen P, Jilma B. Recombinant human activated protein C (rhAPC; drotrecogin alfa [activated]) has minimal effect on markers of coagulation, fibrinolysis, and inflammation in acute human endotoxemia. Blood. 2003;102:2093-2098.
-
(2003)
Blood
, vol.102
, pp. 2093-2098
-
-
Derhaschnig, U.1
Reiter, R.2
Kn̈oble, P.3
Baumgartner, M.4
Keen, P.5
Jilma, B.6
-
22
-
-
34247513330
-
Neutropils and the protein C patway
-
Weitz JI. Neutropils and the protein C patway. Blood. 2003;102:1152-1153.
-
(2003)
Blood
, vol.102
, pp. 1152-1153
-
-
Weitz, J.I.1
-
23
-
-
11144354132
-
Surviving sepsis campaign guidelines for management of severe sepsis and septic shock
-
Dellinger RP, Carlet JM, Masur H, et al. Surviving sepsis campaign guidelines for management of severe sepsis and septic shock. Intense Care Med. 2004;30:536-555.
-
(2004)
Intense Care Med
, vol.30
, pp. 536-555
-
-
Dellinger, R.P.1
Carlet, J.M.2
Masur, H.3
|