A nearly isosteric photosensitive amide-backbone substitution allows enzyme activity switching in ribonuclease S

Journal of the American Chemical Society

Volumn 129, Issue 16, 2007, Pages 4910-4918

  Wildemann, Dirk ^a   Schiene Fischer, Cordelia ^a   Aumüller, Tobias ^a   Bachmann, Annett ^b   Kiefhaber, Thomas ^b   Lücke, Christian ^a   Fischer, Gunter ^a  

^a MAX PLANCK RESEARCH UNIT FOR ENZYMOLOGY OF PROTEIN FOLDING   (Germany)

^b UNIVERSITY OF BASEL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

RIBONUCLEASE S; THERMAL REISOMERIZATION; THIOXOPEPTIDE;

BIOACTIVITY; ENZYME ACTIVITY; ISOMERIZATION; PEPTIDES; PHOTOSENSITIVITY; ULTRAVIOLET RADIATION;

AMIDES;

ALANINE; AMIDE; CYCLIC GMP; POLYPEPTIDE; RIBONUCLEASE; RIBONUCLEASE S; UNCLASSIFIED DRUG;

ARTICLE; CALORIMETRY; CHEMICAL BINDING; CIRCULAR DICHROISM; ENZYME ACTIVITY; ENZYME KINETICS; HYDROLYSIS; ISOMERIZATION; ISOTHERMAL TITRATION CALORIMETRY; PEPTIDE SYNTHESIS; PROTEIN STABILITY; THERMODYNAMICS; ULTRAVIOLET SPECTROSCOPY;

AMIDES; CYCLIC CMP; HYDROLYSIS; ISOMERISM; PHOTOCHEMISTRY; RIBONUCLEASES; THERMODYNAMICS; ULTRAVIOLET RAYS;

EID: 34247520934     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja069048o     Document Type: Article

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