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Volumn 6, Issue 8, 2007, Pages 914-918

SMC proteins, new players in the maintenance of genomic stability

Author keywords

Break induced replication; Cohesins; Collapsed replication forks; Double strand break repair; Homologous recombination; MRX MRN complex; Sister chromatid exchange; SMC complexes; Smc5 Smc6

Indexed keywords

COHESIN; STRUCTURAL MAINTENANCE OF CHROMOSOME 5 PROTEIN; STRUCTURAL MAINTENANCE OF CHROMOSOME 6 PROTEIN; STRUCTURAL PROTEIN; UNCLASSIFIED DRUG;

EID: 34247467472     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.6.8.4107     Document Type: Review
Times cited : (16)

References (54)
  • 1
    • 0038799991 scopus 로고    scopus 로고
    • Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae
    • Paques F, Haber JE. Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae. Microbiol Mol Biol Rev 1999; 63:349-404.
    • (1999) Microbiol Mol Biol Rev , vol.63 , pp. 349-404
    • Paques, F.1    Haber, J.E.2
  • 3
    • 0032715175 scopus 로고    scopus 로고
    • Recombinational repair of DNA damage in Escherichia coli and bacteriophage lambda
    • table of contents
    • Kuzminov A. Recombinational repair of DNA damage in Escherichia coli and bacteriophage lambda. Microbiol Mol Biol Rev 1999; 63:751-813, (table of contents).
    • (1999) Microbiol Mol Biol Rev , vol.63 , pp. 751-813
    • Kuzminov, A.1
  • 5
    • 0033954246 scopus 로고    scopus 로고
    • Replication fork pausing and recombination or "gimme a break
    • Rothstein R, Michel B, Gangloff S. Replication fork pausing and recombination or "gimme a break". Genes Dev 2000; 14:1-10.
    • (2000) Genes Dev , vol.14 , pp. 1-10
    • Rothstein, R.1    Michel, B.2    Gangloff, S.3
  • 6
    • 19344370467 scopus 로고    scopus 로고
    • Mechanism of DNA double-strand break repair by nonhomologous end joining
    • Hefferin ML, Tomkinson AE. Mechanism of DNA double-strand break repair by nonhomologous end joining. DNA Repair (Amst) 2005; 4:639-48.
    • (2005) DNA Repair (Amst) , vol.4 , pp. 639-648
    • Hefferin, M.L.1    Tomkinson, A.E.2
  • 7
    • 0037178722 scopus 로고    scopus 로고
    • Maintenance of genome stability in Saccharomyces cerevisiae
    • Kolodner RD, Putnam CD, Myung K. Maintenance of genome stability in Saccharomyces cerevisiae. Science 2002; 297:552-7.
    • (2002) Science , vol.297 , pp. 552-557
    • Kolodner, R.D.1    Putnam, C.D.2    Myung, K.3
  • 8
    • 0345447604 scopus 로고    scopus 로고
    • Srs2 and Sgs1-Top3 suppress crossovers during double-strand break repair in yeast
    • Ira G, Malkova A, Liberi G, Foiani M, Haber JE. Srs2 and Sgs1-Top3 suppress crossovers during double-strand break repair in yeast. Cell 2003; 115:401-11.
    • (2003) Cell , vol.115 , pp. 401-411
    • Ira, G.1    Malkova, A.2    Liberi, G.3    Foiani, M.4    Haber, J.E.5
  • 9
    • 0347987856 scopus 로고    scopus 로고
    • The Bloom's syndrome helicase suppresses crossing over during homologous recombination
    • Wu L, Hickson ID. The Bloom's syndrome helicase suppresses crossing over during homologous recombination. Nature 2003; 426:870-4.
    • (2003) Nature , vol.426 , pp. 870-874
    • Wu, L.1    Hickson, I.D.2
  • 10
    • 0032535036 scopus 로고    scopus 로고
    • Double-strand break repair by interchromosomal recombination: Suppression of chromosomal translocations
    • Richardson C, Moynahan ME, Jasin M. Double-strand break repair by interchromosomal recombination: Suppression of chromosomal translocations. Genes Dev 1998; 12:3831-42.
    • (1998) Genes Dev , vol.12 , pp. 3831-3842
    • Richardson, C.1    Moynahan, M.E.2    Jasin, M.3
  • 11
    • 0032542364 scopus 로고    scopus 로고
    • Genetic instabilities in human cancers
    • Lengauer C, Kinzler KW, Vogelstein B. Genetic instabilities in human cancers. Nature 1998; 396:643-9.
    • (1998) Nature , vol.396 , pp. 643-649
    • Lengauer, C.1    Kinzler, K.W.2    Vogelstein, B.3
  • 13
    • 0034600975 scopus 로고    scopus 로고
    • Sister chromatid gene conversion is a prominent double-strand break repair pathway in mammalian cells
    • Johnson RD, Jasin M. Sister chromatid gene conversion is a prominent double-strand break repair pathway in mammalian cells. Embo J 2000; 19:3398-407.
    • (2000) Embo J , vol.19 , pp. 3398-3407
    • Johnson, R.D.1    Jasin, M.2
  • 14
    • 0026709385 scopus 로고
    • Sister chromatids are preferred over homologs as substrates for recombinational repair in Saccharomyces cerevisiae
    • Kadyk LC, Hartwell LH. Sister chromatids are preferred over homologs as substrates for recombinational repair in Saccharomyces cerevisiae. Genetics 1992; 132:387-402.
    • (1992) Genetics , vol.132 , pp. 387-402
    • Kadyk, L.C.1    Hartwell, L.H.2
  • 15
    • 23344444636 scopus 로고    scopus 로고
    • Spontaneous homologous recombination is induced by collapsed replication forks that are caused by endogenous DNA single-strand breaks
    • Saleh-Gohari N, Bryant HE, Schultz N, Parker KM, Cassel TN, Helleday T. Spontaneous homologous recombination is induced by collapsed replication forks that are caused by endogenous DNA single-strand breaks. Mol Cell Biol 2005; 25:7158-69.
    • (2005) Mol Cell Biol , vol.25 , pp. 7158-7169
    • Saleh-Gohari, N.1    Bryant, H.E.2    Schultz, N.3    Parker, K.M.4    Cassel, T.N.5    Helleday, T.6
  • 16
    • 0035902544 scopus 로고    scopus 로고
    • Rad52 forms DNA repair and recombination centers during S phase
    • Lisby M, Rothstein R, Mortensen UH. Rad52 forms DNA repair and recombination centers during S phase. Proc Natl Acad Sci USA 2001; 98:8276-82.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 8276-8282
    • Lisby, M.1    Rothstein, R.2    Mortensen, U.H.3
  • 17
    • 0042632901 scopus 로고    scopus 로고
    • Pathways of DNA double-strand break repair during the mammalian cell cycle
    • Rothkamm K, Kruger I, Thompson LH, Lobrich M. Pathways of DNA double-strand break repair during the mammalian cell cycle. Mol Cell Biol 2003; 23:5706-15.
    • (2003) Mol Cell Biol , vol.23 , pp. 5706-5715
    • Rothkamm, K.1    Kruger, I.2    Thompson, L.H.3    Lobrich, M.4
  • 18
    • 3142768860 scopus 로고    scopus 로고
    • Conservative homologous recombination preferentially repairs DNA double-strand breaks in the S phase of the cell cycle in human cells
    • Saleh-Gohari N, Helleday T. Conservative homologous recombination preferentially repairs DNA double-strand breaks in the S phase of the cell cycle in human cells. Nucleic Acids Res 2004; 32:3683-8.
    • (2004) Nucleic Acids Res , vol.32 , pp. 3683-3688
    • Saleh-Gohari, N.1    Helleday, T.2
  • 19
    • 0032530658 scopus 로고    scopus 로고
    • Homologous recombination and nonhomologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells
    • Takata M, Sasaki MS, Sonoda E, Morrison C, Hashimoto M, Utsumi H, Yamaguchi-Iwai Y, Shinohara A, Takeda S. Homologous recombination and nonhomologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells. Embo J 1998; 17:5497-508.
    • (1998) Embo J , vol.17 , pp. 5497-5508
    • Takata, M.1    Sasaki, M.S.2    Sonoda, E.3    Morrison, C.4    Hashimoto, M.5    Utsumi, H.6    Yamaguchi-Iwai, Y.7    Shinohara, A.8    Takeda, S.9
  • 20
    • 1442277710 scopus 로고    scopus 로고
    • Genetic control of sister chromatid recombination: The role of radiation repair (RAD) Genes
    • Fasullo MDZ. Genetic control of sister chromatid recombination: The role of radiation repair (RAD) Genes. Current Genomics 2004; 5:123-36.
    • (2004) Current Genomics , vol.5 , pp. 123-136
    • Fasullo, M.D.Z.1
  • 22
    • 0034922586 scopus 로고    scopus 로고
    • Fasullo M, Giallanza P, Dong Z, Cera C, Bennett T. Saccharomyces cerevisiae rad51 mutants are defective in DNA damage-associated sister chromatid exchanges but exhibit increased rates of homology-directed translocations. Genetics 2001; 158:959-72. . 23. Kadyk LC, Hartwell LH. Replication-dependent sister chromatid recombination in rad1 mutants of Saccharomyces cerevisiae. Genetics 1993; 133:469-87.
    • Fasullo M, Giallanza P, Dong Z, Cera C, Bennett T. Saccharomyces cerevisiae rad51 mutants are defective in DNA damage-associated sister chromatid exchanges but exhibit increased rates of homology-directed translocations. Genetics 2001; 158:959-72. . 23. Kadyk LC, Hartwell LH. Replication-dependent sister chromatid recombination in rad1 mutants of Saccharomyces cerevisiae. Genetics 1993; 133:469-87.
  • 26
    • 33745217560 scopus 로고    scopus 로고
    • Chromosomal Association of the Smc5/6 complex reveals that it functions in differently regulated pathways
    • Betts Lindroos H, Strom L, Itoh T, Katou Y, Shirahige K, Sjogren C. Chromosomal Association of the Smc5/6 complex reveals that it functions in differently regulated pathways. Mol Cell 2006; 22:755-67.
    • (2006) Mol Cell , vol.22 , pp. 755-767
    • Betts Lindroos, H.1    Strom, L.2    Itoh, T.3    Katou, Y.4    Shirahige, K.5    Sjogren, C.6
  • 27
    • 33749511276 scopus 로고    scopus 로고
    • Double-strand breaks arising by replication through a nick are repaired by cohesin-dependent sister-chromatid exchange
    • Cortes-Ledesma F, Aguilera A. Double-strand breaks arising by replication through a nick are repaired by cohesin-dependent sister-chromatid exchange. EMBO Rep 2006; 7:916-26.
    • (2006) EMBO Rep , vol.7 , pp. 916-926
    • Cortes-Ledesma, F.1    Aguilera, A.2
  • 29
    • 33746515537 scopus 로고    scopus 로고
    • Potts PR, Porteus MH, Yu H. Human SMC5/6 complex promotes sister chromatid homologous recombination by recruiting the SMC1/3 cohesin complex to double-strand breaks. Embo J 2006.
    • Potts PR, Porteus MH, Yu H. Human SMC5/6 complex promotes sister chromatid homologous recombination by recruiting the SMC1/3 cohesin complex to double-strand breaks. Embo J 2006.
  • 30
    • 22344439942 scopus 로고    scopus 로고
    • Dynamic molecular linkers of the genome: The first decade of SMC proteins
    • Losada A, Hirano T. Dynamic molecular linkers of the genome: The first decade of SMC proteins. Genes Dev 2005; 19:1269-87.
    • (2005) Genes Dev , vol.19 , pp. 1269-1287
    • Losada, A.1    Hirano, T.2
  • 31
    • 0037178719 scopus 로고    scopus 로고
    • Segregating sister genomes: The molecular biology of chromosome separation
    • Nasmyth K. Segregating sister genomes: The molecular biology of chromosome separation. Science 2002; 297:559-65.
    • (2002) Science , vol.297 , pp. 559-565
    • Nasmyth, K.1
  • 32
    • 25144434235 scopus 로고    scopus 로고
    • Ivanov D, Nasmyth K. A Topological interaction between cohesin rings and a circular minichromosome. Cell 2005; 122:849-60.
    • Ivanov D, Nasmyth K. A Topological interaction between cohesin rings and a circular minichromosome. Cell 2005; 122:849-60.
  • 33
    • 12344261562 scopus 로고    scopus 로고
    • The role of SMC proteins in the responses to DNA damage
    • Lehmann AR. The role of SMC proteins in the responses to DNA damage. DNA Repair (Amst) 2005; 4:309-14.
    • (2005) DNA Repair (Amst) , vol.4 , pp. 309-314
    • Lehmann, A.R.1
  • 35
    • 10944232673 scopus 로고    scopus 로고
    • Postreplicative recruitment of cohesin to double-strand breaks is required for DNA repair
    • Strom L, Lindroos HB, Shirahige K, Sjogren C. Postreplicative recruitment of cohesin to double-strand breaks is required for DNA repair. Mol Cell 2004; 16:1003-15.
    • (2004) Mol Cell , vol.16 , pp. 1003-1015
    • Strom, L.1    Lindroos, H.B.2    Shirahige, K.3    Sjogren, C.4
  • 36
    • 10944262393 scopus 로고    scopus 로고
    • DNA damage response pathway uses histone modification to assemble a double-strand break-specific cohesin domain
    • Unal E, Arbel-Eden A, Sattler U, Shroff R, Lichten M, Haber JE, Koshland D. DNA damage response pathway uses histone modification to assemble a double-strand break-specific cohesin domain. Mol Cell 2004; 16:991-1002.
    • (2004) Mol Cell , vol.16 , pp. 991-1002
    • Unal, E.1    Arbel-Eden, A.2    Sattler, U.3    Shroff, R.4    Lichten, M.5    Haber, J.E.6    Koshland, D.7
  • 37
    • 33751087042 scopus 로고    scopus 로고
    • Condensin is required for chromosome arm cohesion during mitosis
    • Lam WW, Peterson EA, Yeung M, Lavoie BD. Condensin is required for chromosome arm cohesion during mitosis. Genes Dev 2006; 20:2973-84.
    • (2006) Genes Dev , vol.20 , pp. 2973-2984
    • Lam, W.W.1    Peterson, E.A.2    Yeung, M.3    Lavoie, B.D.4
  • 39
    • 0027476083 scopus 로고
    • Identification of new genes required for meiotic recombination in Saccharomyces cerevisiae
    • Ajimura M, Leem SH, Ogawa H. Identification of new genes required for meiotic recombination in Saccharomyces cerevisiae. Genetics 1993; 133:51-66.
    • (1993) Genetics , vol.133 , pp. 51-66
    • Ajimura, M.1    Leem, S.H.2    Ogawa, H.3
  • 40
    • 0026759693 scopus 로고
    • XRS2, a DNA repair gene of Saccharomyces cerevisiae, is needed for meiotic recombination
    • Ivanov EL, Korolev VG, Fabre F. XRS2, a DNA repair gene of Saccharomyces cerevisiae, is needed for meiotic recombination. Genetics 1992; 132:651-64.
    • (1992) Genetics , vol.132 , pp. 651-664
    • Ivanov, E.L.1    Korolev, V.G.2    Fabre, F.3
  • 41
    • 0024986341 scopus 로고
    • The RAD50 gene, a member of the double strand break repair epistasis group, is not required for spontaneous mitotic recombination in yeast
    • Malone RE, Ward T, Lin S, Waring J. The RAD50 gene, a member of the double strand break repair epistasis group, is not required for spontaneous mitotic recombination in yeast. Curr Genet 1990; 18:111-6.
    • (1990) Curr Genet , vol.18 , pp. 111-116
    • Malone, R.E.1    Ward, T.2    Lin, S.3    Waring, J.4
  • 42
    • 0032721091 scopus 로고    scopus 로고
    • The Mre11-Rad50-Xrs2 protein complex facilitates homologous recombination-based double-strand break repair in Saccharomyces cerevisiae
    • Bressan DA, Baxter BK, Petrini JH. The Mre11-Rad50-Xrs2 protein complex facilitates homologous recombination-based double-strand break repair in Saccharomyces cerevisiae. Mol Cell Biol 1999; 19:7681-7.
    • (1999) Mol Cell Biol , vol.19 , pp. 7681-7687
    • Bressan, D.A.1    Baxter, B.K.2    Petrini, J.H.3
  • 43
    • 0037705461 scopus 로고    scopus 로고
    • Multiple recombination pathways for sister chromatid exchange in Saccharomyces cerevisiae: Role of RAD1 and the RAD52 epistasis group genes
    • Dong Z, Fasullo M. Multiple recombination pathways for sister chromatid exchange in Saccharomyces cerevisiae: Role of RAD1 and the RAD52 epistasis group genes. Nucleic Acids Res 2003; 31:2576-85.
    • (2003) Nucleic Acids Res , vol.31 , pp. 2576-2585
    • Dong, Z.1    Fasullo, M.2
  • 46
    • 4544281398 scopus 로고    scopus 로고
    • Choreography of the DNA damage response: Spatiotemporal relationships among checkpoint and repair proteins
    • Lisby M, Barlow JH, Burgess RC, Rothstein R. Choreography of the DNA damage response: Spatiotemporal relationships among checkpoint and repair proteins. Cell 2004; 118:699-713.
    • (2004) Cell , vol.118 , pp. 699-713
    • Lisby, M.1    Barlow, J.H.2    Burgess, R.C.3    Rothstein, R.4
  • 48
    • 0029947714 scopus 로고    scopus 로고
    • Double-strand break repair in the absence of RAD51 in yeast: A possible role for break-induced DNA replication
    • Malkova A, Ivanov EL, Haber JE. Double-strand break repair in the absence of RAD51 in yeast: A possible role for break-induced DNA replication. Proc Natl Acad Sci USA 1996; 93:7131-6.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 7131-7136
    • Malkova, A.1    Ivanov, E.L.2    Haber, J.E.3
  • 49
    • 0025630657 scopus 로고
    • Gene conversion tracts stimulated by HOT1-promoted transcription are long and continuous
    • Voelkel-Meiman K, Roeder GS. Gene conversion tracts stimulated by HOT1-promoted transcription are long and continuous. Genetics 1990; 126:851-67.
    • (1990) Genetics , vol.126 , pp. 851-867
    • Voelkel-Meiman, K.1    Roeder, G.S.2
  • 50
    • 12844289007 scopus 로고    scopus 로고
    • RAD51-dependent break-induced replication differs in kinetics and checkpoint responses from RAD51-mediated gene conversion
    • Malkova A, Naylor ML, Yamaguchi M, Ira G, Haber JE. RAD51-dependent break-induced replication differs in kinetics and checkpoint responses from RAD51-mediated gene conversion. Mol Cell Biol 2005; 25:933-44.
    • (2005) Mol Cell Biol , vol.25 , pp. 933-944
    • Malkova, A.1    Naylor, M.L.2    Yamaguchi, M.3    Ira, G.4    Haber, J.E.5
  • 51
    • 13944261496 scopus 로고    scopus 로고
    • Temporal separation of replication and recombination requires the intra-S checkpoint
    • Meister P, Taddei A, Vernis L, Poidevin M, Gasser SM, Baldacci G. Temporal separation of replication and recombination requires the intra-S checkpoint. J Cell Biol 2005; 168:537-44.
    • (2005) J Cell Biol , vol.168 , pp. 537-544
    • Meister, P.1    Taddei, A.2    Vernis, L.3    Poidevin, M.4    Gasser, S.M.5    Baldacci, G.6
  • 52
    • 33644765203 scopus 로고    scopus 로고
    • Condensin loaded onto the replication fork barrier site in the rRNA gene repeats during S phase in a FOB1-dependent fashion to prevent contraction of a long repetitive array in Saccharomyces cerevisiae
    • Johzuka K, Terasawa M, Ogawa H, Ogawa T, Horiuchi T. Condensin loaded onto the replication fork barrier site in the rRNA gene repeats during S phase in a FOB1-dependent fashion to prevent contraction of a long repetitive array in Saccharomyces cerevisiae. Mol Cell Biol 2006; 26:2226-36.
    • (2006) Mol Cell Biol , vol.26 , pp. 2226-2236
    • Johzuka, K.1    Terasawa, M.2    Ogawa, H.3    Ogawa, T.4    Horiuchi, T.5
  • 53
    • 24644499002 scopus 로고    scopus 로고
    • Recombination regulation by transcription-induced cohesin dissociation in rDNA repeats
    • Kobayashi T, Ganley AR. Recombination regulation by transcription-induced cohesin dissociation in rDNA repeats. Science 2005; 309:1581-4.
    • (2005) Science , vol.309 , pp. 1581-1584
    • Kobayashi, T.1    Ganley, A.R.2
  • 54
    • 2342666131 scopus 로고    scopus 로고
    • SIR2 regulates recombination between different rDNA repeats, but not recombination within individual rRNA genes in yeast
    • Kobayashi T, Horiuchi T, Tongaonkar P, Vu L, Nomura M. SIR2 regulates recombination between different rDNA repeats, but not recombination within individual rRNA genes in yeast. Cell 2004; 117:441-53.
    • (2004) Cell , vol.117 , pp. 441-453
    • Kobayashi, T.1    Horiuchi, T.2    Tongaonkar, P.3    Vu, L.4    Nomura, M.5


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