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Volumn 49, Issue 2, 2007, Pages 115-124

Role of p38α kinase in activation of premature senescence program in transformed mouse fibroblasts

Author keywords

Cell cycle; Oncogenes EIA and cHa ras; P38 kinase; Senescence; Sodium butyrate; Transformation; Wip1 phosphatase

Indexed keywords

BETA GALACTOSIDASE; BUTYRIC ACID DERIVATIVE; E1A ASSOCIATED P300 PROTEIN; HISTONE DEACETYLASE; MITOGEN ACTIVATED PROTEIN KINASE 14; PHOSPHOPROTEIN PHOSPHATASE; PPM1D PROTEIN, MOUSE; TUMOR PROTEIN; UNCLASSIFIED DRUG;

EID: 34247387622     PISSN: 00413771     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (4)

References (31)
  • 1
    • 34247356040 scopus 로고    scopus 로고
    • Russian source
    • Russian source
  • 2
    • 0034193240 scopus 로고    scopus 로고
    • The p65/RelA subunit of NF-κB interacts with actin-containing structures
    • Are A. F., Galkin V. E., Pospelova T. V., Pinaev G. P. 2000. The p65/RelA subunit of NF-κB interacts with actin-containing structures. Exp. Cell Res. 256 : 533-544.
    • (2000) Exp. Cell Res , vol.256 , pp. 533-544
    • Are, A.F.1    Galkin, V.E.2    Pospelova, T.V.3    Pinaev, G.P.4
  • 3
    • 10344262906 scopus 로고    scopus 로고
    • Regulation of the cytoskeleton: An oncogenic function for CDK inhibitions?
    • Besson A., Assoian R. K., Roberts J. M. 2004. Regulation of the cytoskeleton: an oncogenic function for CDK inhibitions? Nat. Rev. Cancer. 4 : 948-955.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 948-955
    • Besson, A.1    Assoian, R.K.2    Roberts, J.M.3
  • 6
    • 0033155404 scopus 로고    scopus 로고
    • Oncoproteins ElAad5 interact with universal inhibitor of cyclin-dependent kinases p21/waf-l and inhibit its activity in ElA + cHa-ras transformants
    • Bulavin D. V., Pospelov V. A., Pospelova T. V. 1999a. Oncoproteins ElAad5 interact with universal inhibitor of cyclin-dependent kinases p21/waf-l and inhibit its activity in ElA + cHa-ras transformants. Mol. Biol. (Moscow). 33 (4) : 641-643.
    • (1999) Mol. Biol. (Moscow) , vol.33 , Issue.4 , pp. 641-643
    • Bulavin, D.V.1    Pospelov, V.A.2    Pospelova, T.V.3
  • 7
    • 0033485261 scopus 로고    scopus 로고
    • Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation
    • Bulavin D. V., Saito S., Hollander M. C., Sakaguchi K., Anderson C. W., Appella E., Fornace A. J. 1999b. Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation. EMBO. J. 18 : 6845-6854.
    • (1999) EMBO. J , vol.18 , pp. 6845-6854
    • Bulavin, D.V.1    Saito, S.2    Hollander, M.C.3    Sakaguchi, K.4    Anderson, C.W.5    Appella, E.6    Fornace, A.J.7
  • 8
    • 0346463059 scopus 로고    scopus 로고
    • High-intensity ras signaling induces premature senescence by activating p38 pathway in primary human fibroblasts
    • Deng Q., Liao R., Wu B.-L., Sun P. 2004. High-intensity ras signaling induces premature senescence by activating p38 pathway in primary human fibroblasts. J. Biol. Chem. 279 : 1050-1059.
    • (2004) J. Biol. Chem , vol.279 , pp. 1050-1059
    • Deng, Q.1    Liao, R.2    Wu, B.-L.3    Sun, P.4
  • 11
    • 21744445111 scopus 로고    scopus 로고
    • The actin cytoskeleton: A key regulator of apoptosis and ageing?
    • Gourlay C. W., Ayscough K. R. 2005. The actin cytoskeleton: a key regulator of apoptosis and ageing? Nature Reviews. Mol. Cell Biol. 6 : 583-589.
    • (2005) Nature Reviews. Mol. Cell Biol , vol.6 , pp. 583-589
    • Gourlay, C.W.1    Ayscough, K.R.2
  • 12
    • 50549218525 scopus 로고
    • The limited in vitro lifetime of human diploid cell strains
    • Hayflick L. 1965. The limited in vitro lifetime of human diploid cell strains. Exp. Cell Res. 37 : 614-636.
    • (1965) Exp. Cell Res , vol.37 , pp. 614-636
    • Hayflick, L.1
  • 13
    • 0345099455 scopus 로고    scopus 로고
    • Cellular senescence, an unpopular yet trustworthy tumor suppressor mechanism
    • Ishikawa F. 2003. Cellular senescence, an unpopular yet trustworthy tumor suppressor mechanism. Cancer Sci. 94 : 944-947.
    • (2003) Cancer Sci , vol.94 , pp. 944-947
    • Ishikawa, F.1
  • 14
    • 0345932931 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase p38 defines the common senescence-signalling pathway
    • Iwasa H., Han J., Ishikawa F. 2003. Mitogen-activated protein kinase p38 defines the common senescence-signalling pathway. Genes Cells. 8: 131-144.
    • (2003) Genes Cells , vol.8 , pp. 131-144
    • Iwasa, H.1    Han, J.2    Ishikawa, F.3
  • 16
    • 16244421738 scopus 로고    scopus 로고
    • Inactivation of p38 kinase delays the onset of senescence in rabbit articular chondrocytes
    • Kang S., Jung M., Kim C.-W., Shin D. Y. 2005. Inactivation of p38 kinase delays the onset of senescence in rabbit articular chondrocytes. Mech. Ageing Develop. 126 : 591-597.
    • (2005) Mech. Ageing Develop , vol.126 , pp. 591-597
    • Kang, S.1    Jung, M.2    Kim, C.-W.3    Shin, D.Y.4
  • 17
  • 18
    • 4143057046 scopus 로고    scopus 로고
    • 2/M transition by triggering the p38 MAPK checkpoint pathway
    • 2/M transition by triggering the p38 MAPK checkpoint pathway. J. Cell Biol. 166 : 517-526.
    • (2004) J. Cell Biol , vol.166 , pp. 517-526
    • Mikhailov, A.1    Shinora, M.2    Rieder, C.L.3
  • 19
    • 0029070887 scopus 로고
    • Selective activation of the INK signaling cascade and c-Jun transcriptional activity by the smal GTPases Rac and Cdc42Hs
    • Minden A., Lin A., Claret F. X., Abo A., Karin M. 1995. Selective activation of the INK signaling cascade and c-Jun transcriptional activity by the smal GTPases Rac and Cdc42Hs. Cell. 81 : 1147-1157.
    • (1995) Cell , vol.81 , pp. 1147-1157
    • Minden, A.1    Lin, A.2    Claret, F.X.3    Abo, A.4    Karin, M.5
  • 20
  • 21
    • 7044231343 scopus 로고    scopus 로고
    • The p16/Ink4a-Rb pathway: Molecular link between cellular senescence and tumor suppression
    • Ohtani N., Yamakoshi K., Takahashi A., Hara E. 2004. The p16/Ink4a-Rb pathway: molecular link between cellular senescence and tumor suppression. J. Med. Invest. 51 : 146-153.
    • (2004) J. Med. Invest , vol.51 , pp. 146-153
    • Ohtani, N.1    Yamakoshi, K.2    Takahashi, A.3    Hara, E.4
  • 23
    • 0038277105 scopus 로고    scopus 로고
    • Tumor cell senescence in cancer treatment
    • Roninson I. B. 2003. Tumor cell senescence in cancer treatment. Cancer Res. 63 : 2705-2715.
    • (2003) Cancer Res , vol.63 , pp. 2705-2715
    • Roninson, I.B.1
  • 24
    • 0034682721 scopus 로고    scopus 로고
    • Cellular senescence: Mitotic clock or culture shock?
    • Sherr C. J., DePinho R. A. 2000. Cellular senescence: mitotic clock or culture shock? Cell. 102 : 407-410.
    • (2000) Cell , vol.102 , pp. 407-410
    • Sherr, C.J.1    DePinho, R.A.2
  • 25
    • 0032562716 scopus 로고    scopus 로고
    • Activation of the protein kinase p38 in the spindle assembly checkpoint and mitotic arrest
    • Takenaka K., Moriguchi T., Nishida E. 1998. Activation of the protein kinase p38 in the spindle assembly checkpoint and mitotic arrest. Science. 280 : 599-602.
    • (1998) Science , vol.280 , pp. 599-602
    • Takenaka, K.1    Moriguchi, T.2    Nishida, E.3
  • 27
    • 22844451843 scopus 로고    scopus 로고
    • A subtle change in p38 MAPK activity is sufficient to suppress in vivo tumorigenesis
    • Timofeev O., Lee T. Yi., Bulavin D. V. 2005. A subtle change in p38 MAPK activity is sufficient to suppress in vivo tumorigenesis. Cell Cycle. 4: 118-120.
    • (2005) Cell Cycle , vol.4 , pp. 118-120
    • Timofeev, O.1    Lee, T.Y.2    Bulavin, D.V.3
  • 29
    • 0036242247 scopus 로고    scopus 로고
    • Sequential activation of the MEK-extracellular signal-activated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence
    • Wang W., Chen J. X., Liao R., Deng Q., Zhou J. J., Huang S., Sun P. 2002. Sequential activation of the MEK-extracellular signal-activated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence. Mol. Cell. Biol. 22 : 3389-3403.
    • (2002) Mol. Cell. Biol , vol.22 , pp. 3389-3403
    • Wang, W.1    Chen, J.X.2    Liao, R.3    Deng, Q.4    Zhou, J.J.5    Huang, S.6    Sun, P.7
  • 30
    • 0033119189 scopus 로고    scopus 로고
    • Expression of catalytically active telomerase does not prevent premature senescence caused by overexpression of oncogenic Ha-Ras in normal human fibroblasts
    • Wei S., Sedivy J. M. 1999. Expression of catalytically active telomerase does not prevent premature senescence caused by overexpression of oncogenic Ha-Ras in normal human fibroblasts. Cancer Res. 59: 1539-1543.
    • (1999) Cancer Res , vol.59 , pp. 1539-1543
    • Wei, S.1    Sedivy, J.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.