메뉴 건너뛰기




Volumn 109, Issue 9, 2007, Pages 4038-4044

Hepcidin antimicrobial peptide transgenic mice exhibit features of the anemia of inflammation

Author keywords

[No Author keywords available]

Indexed keywords

ERYTHROPOIETIN; HEPCIDIN;

EID: 34247366783     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2006-10-051755     Document Type: Article
Times cited : (157)

References (40)
  • 2
    • 0013954846 scopus 로고
    • The anemia of chronic disorders
    • Cartwright GE. The anemia of chronic disorders. Semin Hematol. 1966;3:351-375.
    • (1966) Semin Hematol , vol.3 , pp. 351-375
    • Cartwright, G.E.1
  • 3
    • 0015105285 scopus 로고
    • The anaemia of chronic disorders
    • Cartwright GE, Lee GR. The anaemia of chronic disorders. Br J Haematol. 1971;21:147-152.
    • (1971) Br J Haematol , vol.21 , pp. 147-152
    • Cartwright, G.E.1    Lee, G.R.2
  • 4
    • 14544270445 scopus 로고    scopus 로고
    • Bush JA, Ashenbrucker H, Cartwright GE, Wintrobe MM. The anemia of infection, XX: the kinetics of iron metabolism in the anemia associated with chronic infection. J Clin Invest. 1956;35:89-97.
    • Bush JA, Ashenbrucker H, Cartwright GE, Wintrobe MM. The anemia of infection, XX: the kinetics of iron metabolism in the anemia associated with chronic infection. J Clin Invest. 1956;35:89-97.
  • 5
    • 0001197153 scopus 로고
    • The nature of anaemia in rheumatoid arthritis, V: Red cell survival measured by radioactive chromium
    • Richmond J, Alexander WR, Potter JL, Duthie JJ. The nature of anaemia in rheumatoid arthritis, V: red cell survival measured by radioactive chromium. Ann Rheum Dis. 1961;20:133-137.
    • (1961) Ann Rheum Dis , vol.20 , pp. 133-137
    • Richmond, J.1    Alexander, W.R.2    Potter, J.L.3    Duthie, J.J.4
  • 6
    • 0018141754 scopus 로고
    • Erythropoiesis and mean red-cell lifespan in normal subjects and in patients with the anaemia of active rheumatoid arthritis
    • Dinant HJ, de Maat CE. Erythropoiesis and mean red-cell lifespan in normal subjects and in patients with the anaemia of active rheumatoid arthritis. Br J Haematol. 1978;39:437-444.
    • (1978) Br J Haematol , vol.39 , pp. 437-444
    • Dinant, H.J.1    de Maat, C.E.2
  • 7
    • 34247323287 scopus 로고
    • Erythrocyte survival in rheumatoid arthritis
    • Lewis SM, Porter IH. Erythrocyte survival in rheumatoid arthritis. Ann Rheum Dis. 1960;1:54-58.
    • (1960) Ann Rheum Dis , vol.1 , pp. 54-58
    • Lewis, S.M.1    Porter, I.H.2
  • 8
    • 34247368277 scopus 로고
    • Erythrocyte survival in rheumatoid arthritis
    • Mongan ES, Jacox RF. Erythrocyte survival in rheumatoid arthritis. Arthritis Rheum. 1964;7:481-489.
    • (1964) Arthritis Rheum , vol.7 , pp. 481-489
    • Mongan, E.S.1    Jacox, R.F.2
  • 9
    • 0025340165 scopus 로고
    • Anaemia of rheumatoid arthritis: Serum erythropoietin concentrations and red cell distribution width in relation to iron status
    • Nielsen OJ, Andersen LS, Ludwigsen E, et al. Anaemia of rheumatoid arthritis: serum erythropoietin concentrations and red cell distribution width in relation to iron status. Ann Rheum Dis. 1990;49:349-353.
    • (1990) Ann Rheum Dis , vol.49 , pp. 349-353
    • Nielsen, O.J.1    Andersen, L.S.2    Ludwigsen, E.3
  • 10
    • 0023217503 scopus 로고
    • Serum erythropoietin in rheumatoid arthritis and other inflammatory arthritides: Relationship to anaemia and the effect of anti-inflammatory treatment
    • Birgegard G, Hallgren R, Caro J. Serum erythropoietin in rheumatoid arthritis and other inflammatory arthritides: relationship to anaemia and the effect of anti-inflammatory treatment. Br J Haematol. 1987;65:479-483.
    • (1987) Br J Haematol , vol.65 , pp. 479-483
    • Birgegard, G.1    Hallgren, R.2    Caro, J.3
  • 11
    • 0023769893 scopus 로고
    • Serum immunoreactive erythropoietin in rheumatoid arthritis: Impaired response to anemia
    • Hochberg MC, Arnold CM, Hogans BB, Spivak JL. Serum immunoreactive erythropoietin in rheumatoid arthritis: impaired response to anemia. Arthritis Rheum. 1988;31:1318-1321.
    • (1988) Arthritis Rheum , vol.31 , pp. 1318-1321
    • Hochberg, M.C.1    Arnold, C.M.2    Hogans, B.B.3    Spivak, J.L.4
  • 12
    • 0023204872 scopus 로고
    • Blunted erythropoietin response to anaemia in rheumatoid arthritis
    • Baer AN, Dessypris EN, Goldwasser E, Krantz SB. Blunted erythropoietin response to anaemia in rheumatoid arthritis. Br J Haematol. 1987;66:559-564.
    • (1987) Br J Haematol , vol.66 , pp. 559-564
    • Baer, A.N.1    Dessypris, E.N.2    Goldwasser, E.3    Krantz, S.B.4
  • 13
    • 0025858826 scopus 로고
    • Erythropoietin deficiency in the anaemia of chronic disorders
    • Boyd HK, Lappin TR. Erythropoietin deficiency in the anaemia of chronic disorders. Eur J Haematol. 1991;46:198-201.
    • (1991) Eur J Haematol , vol.46 , pp. 198-201
    • Boyd, H.K.1    Lappin, T.R.2
  • 14
    • 2342510407 scopus 로고    scopus 로고
    • IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin
    • Nemeth E, Rivera S, Gabayan V, et al. IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin. J Clin Invest. 2004;113:1271-1276.
    • (2004) J Clin Invest , vol.113 , pp. 1271-1276
    • Nemeth, E.1    Rivera, S.2    Gabayan, V.3
  • 15
    • 0035896581 scopus 로고    scopus 로고
    • A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload
    • Pigeon C, Ilyin G, Courselaud B, et al. A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload. J Biol Chem. 2001;276:7811-7819.
    • (2001) J Biol Chem , vol.276 , pp. 7811-7819
    • Pigeon, C.1    Ilyin, G.2    Courselaud, B.3
  • 16
    • 0036791486 scopus 로고    scopus 로고
    • The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation
    • Nicolas G, Chauvet C, Viatte L, et al. The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation. J Clin Invest. 2002;110:1037-1044.
    • (2002) J Clin Invest , vol.110 , pp. 1037-1044
    • Nicolas, G.1    Chauvet, C.2    Viatte, L.3
  • 17
    • 10844258104 scopus 로고    scopus 로고
    • Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
    • Nemeth E, Tuttle MS, Powelson J, et al. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science. 2004;306:2090-2093.
    • (2004) Science , vol.306 , pp. 2090-2093
    • Nemeth, E.1    Tuttle, M.S.2    Powelson, J.3
  • 18
    • 20444416123 scopus 로고    scopus 로고
    • The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis
    • Donovan A, Lima CA, Pinkus JL, et al. The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis. Cell Metab. 2005;1:191-200.
    • (2005) Cell Metab , vol.1 , pp. 191-200
    • Donovan, A.1    Lima, C.A.2    Pinkus, J.L.3
  • 20
    • 0037007064 scopus 로고    scopus 로고
    • Severe iron deficiency anemia in transgenic mice expressing liver hepcidin
    • Nicolas G, Bennoun M, Porteu A, et al. Severe iron deficiency anemia in transgenic mice expressing liver hepcidin. Proc Natl Acad Sci U S A. 2002;99:4596-4601.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 4596-4601
    • Nicolas, G.1    Bennoun, M.2    Porteu, A.3
  • 21
    • 1642315903 scopus 로고    scopus 로고
    • Functional differences between hepcidin 1 and 2 in transgenic mice
    • Lou DQ, Nicolas G, Lesbordes JC, et al. Functional differences between hepcidin 1 and 2 in transgenic mice. Blood. 2004;103:2816-2821.
    • (2004) Blood , vol.103 , pp. 2816-2821
    • Lou, D.Q.1    Nicolas, G.2    Lesbordes, J.C.3
  • 22
    • 13544252463 scopus 로고    scopus 로고
    • Hepcidin excess induces the sequestration of iron and exacerbates tumor-associated anemia
    • Rivera S, Liu L, Nemeth E, Gabayan V, Sorensen OE, Ganz T. Hepcidin excess induces the sequestration of iron and exacerbates tumor-associated anemia. Blood. 2005;105:1797-1802.
    • (2005) Blood , vol.105 , pp. 1797-1802
    • Rivera, S.1    Liu, L.2    Nemeth, E.3    Gabayan, V.4    Sorensen, O.E.5    Ganz, T.6
  • 23
    • 0029763587 scopus 로고    scopus 로고
    • Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice
    • Kistner A, Gossen M, Zimmermann F, et al. Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice. Proc Natl Acad Sci U S A. 1996;93:10933-10938.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 10933-10938
    • Kistner, A.1    Gossen, M.2    Zimmermann, F.3
  • 25
    • 33645525540 scopus 로고    scopus 로고
    • Chronic hepcidin induction causes hyposideremia and alters the pattern of cellular iron accumulation in hemochromatotic mice
    • Viatte L, Nicolas G, Lou DQ, et al. Chronic hepcidin induction causes hyposideremia and alters the pattern of cellular iron accumulation in hemochromatotic mice. Blood. 2006;107:2952-2958.
    • (2006) Blood , vol.107 , pp. 2952-2958
    • Viatte, L.1    Nicolas, G.2    Lou, D.Q.3
  • 26
    • 0037111732 scopus 로고    scopus 로고
    • Inappropriate expression of hepcidin is associated with iron refractory anemia: Implications for the anemia of chronic disease
    • Weinstein DA, Roy CN, Fleming MD, Loda MF, Wolfsdorf JI, Andrews NC. Inappropriate expression of hepcidin is associated with iron refractory anemia: implications for the anemia of chronic disease. Blood. 2002;100:3776-3781.
    • (2002) Blood , vol.100 , pp. 3776-3781
    • Weinstein, D.A.1    Roy, C.N.2    Fleming, M.D.3    Loda, M.F.4    Wolfsdorf, J.I.5    Andrews, N.C.6
  • 27
    • 0001501628 scopus 로고
    • Transfer of iron from serum iron-binding protein to human reticylocytes
    • Jandl JH. Transfer of iron from serum iron-binding protein to human reticylocytes. J Clin Invest. 1959;38:161.
    • (1959) J Clin Invest , vol.38 , pp. 161
    • Jandl, J.H.1
  • 28
    • 0023522698 scopus 로고
    • Hereditary hypotransferrinemia with hemosiderosis, a murine disorder resembling human atransferrinemia
    • Bernstein SE. Hereditary hypotransferrinemia with hemosiderosis, a murine disorder resembling human atransferrinemia. J Lab Clin Med. 1987;110:690-705.
    • (1987) J Lab Clin Med , vol.110 , pp. 690-705
    • Bernstein, S.E.1
  • 30
    • 0032732042 scopus 로고    scopus 로고
    • Role of the macrophage in erythropoiesis
    • Sadahira Y, Mori M. Role of the macrophage in erythropoiesis. Pathol Int. 1999;49:841-848.
    • (1999) Pathol Int , vol.49 , pp. 841-848
    • Sadahira, Y.1    Mori, M.2
  • 31
    • 0032170572 scopus 로고    scopus 로고
    • Anemia in children with cancer is associated with decreased erythropoietic activity and not with inadequate erythropoietin production
    • Corazza F, Beguin Y, Bergmann P, et al. Anemia in children with cancer is associated with decreased erythropoietic activity and not with inadequate erythropoietin production. Blood. 1998;92:1793-1798.
    • (1998) Blood , vol.92 , pp. 1793-1798
    • Corazza, F.1    Beguin, Y.2    Bergmann, P.3
  • 32
    • 0030985205 scopus 로고    scopus 로고
    • Anaemia of lung cancer is due to impaired erythroid marrow response to erythropoietin stimulation as well as relative inadequacy of erythropoietin production
    • Dowlati A, R'Zik S, Fillet G, Beguin Y. Anaemia of lung cancer is due to impaired erythroid marrow response to erythropoietin stimulation as well as relative inadequacy of erythropoietin production. Br J Haematol. 1997;97:297-299.
    • (1997) Br J Haematol , vol.97 , pp. 297-299
    • Dowlati, A.1    R'Zik, S.2    Fillet, G.3    Beguin, Y.4
  • 33
    • 33645509481 scopus 로고    scopus 로고
    • Hepcidin inhibits in vitro erythroid colony formation at reduced erythropoietin concentrations
    • Dallalio G, Law E, Means RT Jr. Hepcidin inhibits in vitro erythroid colony formation at reduced erythropoietin concentrations. Blood. 2006;107:2702-2704.
    • (2006) Blood , vol.107 , pp. 2702-2704
    • Dallalio, G.1    Law, E.2    Means Jr., R.T.3
  • 34
    • 22044438662 scopus 로고    scopus 로고
    • Hemoglobin levels correlate with interleukin-6 levels in patients with advanced untreated epithelial ovarian cancer: Role of inflammation in cancer-related anemia
    • Maccio A, Madeddu C, Massa D, et al. Hemoglobin levels correlate with interleukin-6 levels in patients with advanced untreated epithelial ovarian cancer: role of inflammation in cancer-related anemia. Blood. 2005;106:362-367.
    • (2005) Blood , vol.106 , pp. 362-367
    • Maccio, A.1    Madeddu, C.2    Massa, D.3
  • 36
    • 0033768311 scopus 로고    scopus 로고
    • Cartilage destruction and bone erosion in arthritis: The role of tumour necrosis factor alpha
    • Williams RO, Feldmann M, Maini RN. Cartilage destruction and bone erosion in arthritis: the role of tumour necrosis factor alpha. Ann Rheum Dis. 2000;59:i75-i80.
    • (2000) Ann Rheum Dis , vol.59
    • Williams, R.O.1    Feldmann, M.2    Maini, R.N.3
  • 37
    • 0026039673 scopus 로고
    • Transgenic mice expressing human tumour necrosis factor: A predictive genetic model of arthritis
    • Keffer J, Probert L, Cazlaris H, et al. Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritis. EMBO J. 1991;10:4025-4031.
    • (1991) EMBO J , vol.10 , pp. 4025-4031
    • Keffer, J.1    Probert, L.2    Cazlaris, H.3
  • 38
    • 0024501951 scopus 로고
    • Cachectin/tumor necrosis factor-alpha alters red blood cell kinetics and induces anemia in vivo
    • Moldawer LL, Marano MA, Wei H, et al. Cachectin/tumor necrosis factor-alpha alters red blood cell kinetics and induces anemia in vivo. FASEB J. 1989;3:1637-1643.
    • (1989) FASEB J , vol.3 , pp. 1637-1643
    • Moldawer, L.L.1    Marano, M.A.2    Wei, H.3
  • 39
    • 33744534202 scopus 로고    scopus 로고
    • Tumour necrosis factor alpha causes hypoferraemia and reduced intestinal iron absorption in mice
    • Laftah AH, Sharma N, Brookes MJ, et al. Tumour necrosis factor alpha causes hypoferraemia and reduced intestinal iron absorption in mice. Biochem J. 2006;27:27.
    • (2006) Biochem J , vol.27 , pp. 27
    • Laftah, A.H.1    Sharma, N.2    Brookes, M.J.3
  • 40
    • 0038662619 scopus 로고    scopus 로고
    • Hepcidin, a putative mediator of anemia of inflammation, is a type II acutephase protein
    • Nemeth E, Valore EV, Territo M, Schiller G, Lichtenstein A, Ganz T. Hepcidin, a putative mediator of anemia of inflammation, is a type II acutephase protein. Blood. 2003;101:2461-2463.
    • (2003) Blood , vol.101 , pp. 2461-2463
    • Nemeth, E.1    Valore, E.V.2    Territo, M.3    Schiller, G.4    Lichtenstein, A.5    Ganz, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.