메뉴 건너뛰기




Volumn 37, Issue 5, 2007, Pages 723-734

Interference of methysergide, a specific 5-hydroxytryptamine receptor antagonist, with airway chronic allergic inflammation and remodelling in a murine model of asthma

Author keywords

5 hydroxytryptamine; Asthma; Lung remodelling; Methysergide; Prolonged allergen exposure

Indexed keywords

ALLERGEN; ANTIGEN; COLLAGEN; CYTOKINE; FIBRONECTIN; GAMMA INTERFERON; IMMUNOGLOBULIN E; METHYSERGIDE; NEUTRALIZING ANTIBODY; OVALBUMIN; SEROTONIN; SEROTONIN ANTAGONIST;

EID: 34247343774     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2007.02700.x     Document Type: Article
Times cited : (31)

References (68)
  • 3
    • 0028965187 scopus 로고
    • Is asthma a fibrotic disease?
    • Roberts CR. Is asthma a fibrotic disease? Chest 1995 107: 111S 7S.
    • (1995) Chest , vol.107
    • Roberts, C.R.1
  • 4
    • 0030895523 scopus 로고    scopus 로고
    • The measurement of reticular basement membrane and submucosal collagen in the asthmatic airway
    • Wilson JW, Li X. The measurement of reticular basement membrane and submucosal collagen in the asthmatic airway. Clin Exp Allergy 1997 27: 363 71.
    • (1997) Clin Exp Allergy , vol.27 , pp. 363-71
    • Wilson, J.W.1    Li, X.2
  • 7
    • 5444268690 scopus 로고    scopus 로고
    • A role for eosinophils in airway remodelling in asthma
    • Kay AB, Phipps S, Robinson DS. A role for eosinophils in airway remodelling in asthma. Trends Immunol 2004 25: 477 82.
    • (2004) Trends Immunol , vol.25 , pp. 477-82
    • Kay, A.B.1    Phipps, S.2    Robinson, D.S.3
  • 8
    • 4544274172 scopus 로고    scopus 로고
    • A critical role for eosinophils in allergic airways remodeling
    • Humbles AA, Lloyd CM, Mcmillan SJ et al. A critical role for eosinophils in allergic airways remodeling. Science 2004 305: 1776 9.
    • (2004) Science , vol.305 , pp. 1776-9
    • Humbles, A.A.1    Lloyd, C.M.2    McMillan, S.J.3
  • 9
    • 85047693849 scopus 로고    scopus 로고
    • Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics
    • Flood-Page P, Menzies-Gow A, Phipps S et al. Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics. J Clin Invest 2003 112: 1029 36.
    • (2003) J Clin Invest , vol.112 , pp. 1029-36
    • Flood-Page, P.1    Menzies-Gow, A.2    Phipps, S.3
  • 10
    • 1642372399 scopus 로고    scopus 로고
    • Prolonged allergen challenge in mice leads to persistent airway remodelling
    • McMillan SJ, Lloyd CM. Prolonged allergen challenge in mice leads to persistent airway remodelling. Clin Exp Allergy 2004 34: 497 507.
    • (2004) Clin Exp Allergy , vol.34 , pp. 497-507
    • McMillan, S.J.1    Lloyd, C.M.2
  • 11
    • 14844355588 scopus 로고    scopus 로고
    • Airway remodelling and inflammation in sheep lungs after chronic airway challenge with house dust mite
    • Snibson KJ, Bischof RJ, Slocombe RF, Meeusen EN. Airway remodelling and inflammation in sheep lungs after chronic airway challenge with house dust mite. Clin Exp Allergy 2005 35: 146 52.
    • (2005) Clin Exp Allergy , vol.35 , pp. 146-52
    • Snibson, K.J.1    Bischof, R.J.2    Slocombe, R.F.3    Meeusen, E.N.4
  • 12
    • 0028229422 scopus 로고
    • Piecemeal degranulation of mast cells in the inflammatory eyelid lesions of interleukin-4 transgenic mice. Evidence of mast cell histamine release in vivo by diamine oxidase-gold enzyme-affinity ultrastructural cytochemistry
    • Dvorak AM, Tepper RI, Weller PF et al. Piecemeal degranulation of mast cells in the inflammatory eyelid lesions of interleukin-4 transgenic mice. Evidence of mast cell histamine release in vivo by diamine oxidase-gold enzyme-affinity ultrastructural cytochemistry. Blood 1994 83: 3600 12.
    • (1994) Blood , vol.83 , pp. 3600-12
    • Dvorak, A.M.1    Tepper, R.I.2    Weller, P.F.3
  • 13
    • 0029971898 scopus 로고    scopus 로고
    • Role of mast cells, eosinophils and IL-5 in the development of airway hyperresponsiveness in sensitized mice
    • Nagai H, Yamaguchi S, Maeda Y, Tanaka H. Role of mast cells, eosinophils and IL-5 in the development of airway hyperresponsiveness in sensitized mice. Clin Exp Allergy 1996 26: 642 7.
    • (1996) Clin Exp Allergy , vol.26 , pp. 642-7
    • Nagai, H.1    Yamaguchi, S.2    Maeda, Y.3    Tanaka, H.4
  • 14
    • 0033186642 scopus 로고    scopus 로고
    • Comparative study of platelet histamine and serotonin with their corresponding plasma oxidases in asthmatics with normals
    • Matkar NM, Rupwate RU, Desai NK, Kamat SR. Comparative study of platelet histamine and serotonin with their corresponding plasma oxidases in asthmatics with normals. J Assoc Physicians India 1999 47: 878 82.
    • (1999) J Assoc Physicians India , vol.47 , pp. 878-82
    • Matkar, N.M.1    Rupwate, R.U.2    Desai, N.K.3    Kamat, S.R.4
  • 15
    • 0032943468 scopus 로고    scopus 로고
    • Anaphylactic bronchoconstriction in BP2 mice: Interactions between serotonin and acetylcholine
    • Eum SY, Norel X, Lefort J, Labat C, Vargaftig BB, Brink C. Anaphylactic bronchoconstriction in BP2 mice: interactions between serotonin and acetylcholine. Br J Pharmacol 1999 126: 312 6.
    • (1999) Br J Pharmacol , vol.126 , pp. 312-6
    • Eum, S.Y.1    Norel, X.2    Lefort, J.3    Labat, C.4    Vargaftig, B.B.5    Brink, C.6
  • 16
    • 2442538078 scopus 로고    scopus 로고
    • The serotoninergic receptors of human dendritic cells: Identification and coupling to cytokine release
    • Idzko M, Panther E, Stratz C et al. The serotoninergic receptors of human dendritic cells: identification and coupling to cytokine release. J Immunol 2004 172: 6011 9.
    • (2004) J Immunol , vol.172 , pp. 6011-9
    • Idzko, M.1    Panther, E.2    Stratz, C.3
  • 17
    • 0028183017 scopus 로고
    • International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (serotonin)
    • Hoyer D, Clarke DE, Fozard JR et al. International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (serotonin). Pharmacol Rev 1994 46: 157 203.
    • (1994) Pharmacol Rev , vol.46 , pp. 157-203
    • Hoyer, D.1    Clarke, D.E.2    Fozard, J.R.3
  • 18
    • 0029156503 scopus 로고
    • Expression of serotonin receptor mRNAs in blood vessels
    • Ullmer C, Schmuck K, Kalkman HO, Lubbert H. Expression of serotonin receptor mRNAs in blood vessels. FEBS Lett 1995 370: 215 21.
    • (1995) FEBS Lett , vol.370 , pp. 215-21
    • Ullmer, C.1    Schmuck, K.2    Kalkman, H.O.3    Lubbert, H.4
  • 19
    • 0033774752 scopus 로고    scopus 로고
    • 5-hydroxytryptamine and the pulmonary circulation: Receptors, transporters and relevance to pulmonary arterial hypertension
    • MacLean MR, Herve P, Eddahibi S, Adnot S. 5-hydroxytryptamine and the pulmonary circulation: receptors, transporters and relevance to pulmonary arterial hypertension. Br J Pharmacol 2000 131: 161 8.
    • (2000) Br J Pharmacol , vol.131 , pp. 161-8
    • MacLean, M.R.1    Herve, P.2    Eddahibi, S.3    Adnot, S.4
  • 20
    • 33846065962 scopus 로고    scopus 로고
    • Serotoninergic receptors on human airway epithelial cells
    • Bayer H, Muller T, Myrtek D et al. Serotoninergic receptors on human airway epithelial cells. Am J Respir Cell Mol Biol 2007 36: 85 93.
    • (2007) Am J Respir Cell Mol Biol , vol.36 , pp. 85-93
    • Bayer, H.1    Muller, T.2    Myrtek, D.3
  • 21
    • 0027359069 scopus 로고
    • Stimulation of splenic T-lymphocyte function by endogenous serotonin and by low-dose exogenous serotonin
    • Young MR, Kut JL, Coogan MP, Wright MA, Young ME, Matthews J. Stimulation of splenic T-lymphocyte function by endogenous serotonin and by low-dose exogenous serotonin. Immunology 1993 80: 395 400.
    • (1993) Immunology , vol.80 , pp. 395-400
    • Young, M.R.1    Kut, J.L.2    Coogan, M.P.3    Wright, M.A.4    Young, M.E.5    Matthews, J.6
  • 22
    • 0028988738 scopus 로고
    • Serotonin upregulates mitogen-stimulated B lymphocyte proliferation through 5-HT1A receptors
    • Iken K, Chheng S, Fargin A, Goulet AC, Kouassi E. Serotonin upregulates mitogen-stimulated B lymphocyte proliferation through 5-HT1A receptors. Cell Immunol 1995 163: 1 9.
    • (1995) Cell Immunol , vol.163 , pp. 1-9
    • Iken, K.1    Chheng, S.2    Fargin, A.3    Goulet, A.C.4    Kouassi, E.5
  • 23
    • 0030043884 scopus 로고    scopus 로고
    • Secretion of IL-16 (lymphocyte chemoattractant factor) from serotonin-stimulated CD8+T cells in vitro
    • Laberge S, Cruikshank WW, Beer DJ, Center DM. Secretion of IL-16 (lymphocyte chemoattractant factor) from serotonin-stimulated CD8+T cells in vitro. J Immunol 1996 156: 310 5.
    • (1996) J Immunol , vol.156 , pp. 310-5
    • Laberge, S.1    Cruikshank, W.W.2    Beer, D.J.3    Center, D.M.4
  • 24
    • 0037330870 scopus 로고    scopus 로고
    • Differential effect of serotonin on cytokine production in lipopolysaccharide-stimulated human peripheral blood mononuclear cells: Involvement of 5-hydroxytryptamine2A receptors
    • Cloez-Tayarani I, Petit-Bertron AF, Venters HD, Cavaillon JM. Differential effect of serotonin on cytokine production in lipopolysaccharide- stimulated human peripheral blood mononuclear cells: involvement of 5-hydroxytryptamine2A receptors. Int Immunol 2003 15: 233 40.
    • (2003) Int Immunol , vol.15 , pp. 233-40
    • Cloez-Tayarani, I.1    Petit-Bertron, A.F.2    Venters, H.D.3    Cavaillon, J.M.4
  • 25
    • 24744458366 scopus 로고    scopus 로고
    • Modulation of the induction of lung and airway allergy in the offspring of IFN-γ-treated mother mice
    • Lima C, Souza VMO, Faquim-Mauro EL et al. Modulation of the induction of lung and airway allergy in the offspring of IFN-γ-treated mother mice. J Immunol 2005 175: 3554 9.
    • (2005) J Immunol , vol.175 , pp. 3554-9
    • Lima, C.1    Souza, V.M.O.2    Faquim-Mauro, E.L.3
  • 26
    • 0037369330 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha-induced synthesis of interleukin-16 in airway epithelial cells: Priming for serotonin stimulation
    • Little FF, Lynch E, Fine G, Center DM, Cruikshank WW. Tumor necrosis factor-alpha-induced synthesis of interleukin-16 in airway epithelial cells: priming for serotonin stimulation. Am J Respir Cell Mol Biol 2003 28: 354 62.
    • (2003) Am J Respir Cell Mol Biol , vol.28 , pp. 354-62
    • Little, F.F.1    Lynch, E.2    Fine, G.3    Center, D.M.4    Cruikshank, W.W.5
  • 27
    • 0014253487 scopus 로고
    • The hypotensive action of 5-hydroxytryptamine (5-HT) in anaesthetised and pithed rats
    • Fozard JR, Leach GDH. The hypotensive action of 5-hydroxytryptamine (5-HT) in anaesthetised and pithed rats. Eur J Pharmacol 1968 2: 239 49.
    • (1968) Eur J Pharmacol , vol.2 , pp. 239-49
    • Fozard, J.R.1    Leach, G.D.H.2
  • 28
    • 0035066699 scopus 로고    scopus 로고
    • Mechanism of airway hyperresponsiveness to adenosine induced by allergen challenge in actively sensitized Brown Norway rats
    • Hannon JP, Tigani B, Williams I, Mazzoni L, Fozard JR. Mechanism of airway hyperresponsiveness to adenosine induced by allergen challenge in actively sensitized Brown Norway rats. Br J Pharmacol 2001 132: 1509 23.
    • (2001) Br J Pharmacol , vol.132 , pp. 1509-23
    • Hannon, J.P.1    Tigani, B.2    Williams, I.3    Mazzoni, L.4    Fozard, J.R.5
  • 29
    • 0014678547 scopus 로고
    • Homologous passive cutaneous anaphylactic activity of mouse antiserum during the course of immunization
    • Mota I, Wong D. Homologous passive cutaneous anaphylactic activity of mouse antiserum during the course of immunization. Life Sci 1969 8: 813 20.
    • (1969) Life Sci , vol.8 , pp. 813-20
    • Mota, I.1    Wong, D.2
  • 30
    • 0037237943 scopus 로고    scopus 로고
    • Persistence of bronchopulmonary hyper-reactivity and eosinophilic lung inflammation after anti-IL-5 or -IL-13 treatment in allergic BALB/c and IL-4Ralpha knockout mice
    • Proust B, Nahori MA, Ruffie C, Lefort J, Vargaftig BB. Persistence of bronchopulmonary hyper-reactivity and eosinophilic lung inflammation after anti-IL-5 or -IL-13 treatment in allergic BALB/c and IL-4Ralpha knockout mice. Clin Exp Allergy 2003 33: 119 31.
    • (2003) Clin Exp Allergy , vol.33 , pp. 119-31
    • Proust, B.1    Nahori, M.A.2    Ruffie, C.3    Lefort, J.4    Vargaftig, B.B.5
  • 32
    • 25444471792 scopus 로고    scopus 로고
    • Quantification of collagen and proteoglycan deposition in a murine model of airway remodelling
    • Reinhardt AK, Bottoms SE, Laurent GJ, McAnulty RJ. Quantification of collagen and proteoglycan deposition in a murine model of airway remodelling. Respir Res 2005 8: 6 30.
    • (2005) Respir Res , vol.8 , pp. 6-30
    • Reinhardt, A.K.1    Bottoms, S.E.2    Laurent, G.J.3    McAnulty, R.J.4
  • 33
    • 33747411773 scopus 로고    scopus 로고
    • Compartmentalization of intracellular proinflammatory cytokines in bronchial intraepithelial T cells of stable lung transplant patients
    • Hodge G, Hodge S, Reynolds PN, Holmes M. Compartmentalization of intracellular proinflammatory cytokines in bronchial intraepithelial T cells of stable lung transplant patients. Clin Exp Immunol 2006 145: 413 9.
    • (2006) Clin Exp Immunol , vol.145 , pp. 413-9
    • Hodge, G.1    Hodge, S.2    Reynolds, P.N.3    Holmes, M.4
  • 34
    • 0034529934 scopus 로고    scopus 로고
    • Time course of inflammatory and remodeling events in a murine model of asthma: Effect of steroid treatment
    • Trifilieff A, El Hashim A, Bertrand C. Time course of inflammatory and remodeling events in a murine model of asthma: effect of steroid treatment. Am J Physiol Lung Cell Mol Physiol 2000 279: L1120 8.
    • (2000) Am J Physiol Lung Cell Mol Physiol , vol.279
    • Trifilieff, A.1    El Hashim, A.2    Bertrand, C.3
  • 35
    • 0037349125 scopus 로고    scopus 로고
    • Role of Th2 responses in the development of allergen-induced airway remodelling in a murine model of allergic asthma
    • Komai M, Tanaka H, Masuda T et al. Role of Th2 responses in the development of allergen-induced airway remodelling in a murine model of allergic asthma. Br J Pharmacol 2003 138: 912 20.
    • (2003) Br J Pharmacol , vol.138 , pp. 912-20
    • Komai, M.1    Tanaka, H.2    Masuda, T.3
  • 37
    • 0029847368 scopus 로고    scopus 로고
    • Functional diversity of helper T lymphocytes
    • Abbas AK, Murphy KM, Sher A. Functional diversity of helper T lymphocytes. Nature 1996 383: 787.
    • (1996) Nature , vol.383 , pp. 787
    • Abbas, A.K.1    Murphy, K.M.2    Sher, A.3
  • 38
    • 0023839463 scopus 로고
    • Interferon-γ regulates the isotypes of immunoglobulin secreted during in vivo humoral immune responses
    • Finkelman FD, Katona IM, Mosmann TR, Coffman RL. Interferon-γ regulates the isotypes of immunoglobulin secreted during in vivo humoral immune responses. J Immunol 1988 140: 1022.
    • (1988) J Immunol , vol.140 , pp. 1022
    • Finkelman, F.D.1    Katona, I.M.2    Mosmann, T.R.3    Coffman, R.L.4
  • 39
    • 8044250881 scopus 로고    scopus 로고
    • Regulation of the interleukin (IL)-12Rß2 subunit expression in developing T helper 1 (Th1) and Th2 cells
    • Szabo SJ, Dighe AS, Gubler U, Murphy KM. Regulation of the interleukin (IL)-12Rß2 subunit expression in developing T helper 1 (Th1) and Th2 cells. J Exp Med 1997 185: 817.
    • (1997) J Exp Med , vol.185 , pp. 817
    • Szabo, S.J.1    Dighe, A.S.2    Gubler, U.3    Murphy, K.M.4
  • 40
    • 0027409773 scopus 로고
    • Interferon gamma regulates antigen-induced eosinophil recruitment into the mouse airways by inhibiting the infiltration of CD4+T cells
    • Iwamoto I, Nakajima H, Endo H, Yoshida S. Interferon gamma regulates antigen-induced eosinophil recruitment into the mouse airways by inhibiting the infiltration of CD4+T cells. J Exp Med 1993 177: 573.
    • (1993) J Exp Med , vol.177 , pp. 573
    • Iwamoto, I.1    Nakajima, H.2    Endo, H.3    Yoshida, S.4
  • 41
    • 0027486985 scopus 로고
    • Aerosolized recombinant interferon-gamma prevents antigen-induced eosinophil recruitment in mouse trachea
    • Nakajima H, Iwamoto I, Yoshida S. Aerosolized recombinant interferon-gamma prevents antigen-induced eosinophil recruitment in mouse trachea. Am Rev Respir Dis 1993 148: 1102.
    • (1993) Am Rev Respir Dis , vol.148 , pp. 1102
    • Nakajima, H.1    Iwamoto, I.2    Yoshida, S.3
  • 43
    • 0032945548 scopus 로고    scopus 로고
    • Allergen-specific Th1 cells fail to counterbalance Th2 cell-induced airway hyperreactivity but cause severe airway inflammation
    • Hansen G, Berry G, DeKruyff RH, Umetsu DT. Allergen-specific Th1 cells fail to counterbalance Th2 cell-induced airway hyperreactivity but cause severe airway inflammation. J Clin Invest 1999 103: 175.
    • (1999) J Clin Invest , vol.103 , pp. 175
    • Hansen, G.1    Berry, G.2    Dekruyff, R.H.3    Umetsu, D.T.4
  • 44
    • 0033557718 scopus 로고    scopus 로고
    • Modulation of airway inflammation by passive transfer of allergen-specific Th1 and Th2 cells in a mouse model of asthma
    • Randolph DA, Carruthers CJ, Szabo SJ, Murphy KM, Chaplin DD. Modulation of airway inflammation by passive transfer of allergen-specific Th1 and Th2 cells in a mouse model of asthma. J Immunol 1999 162: 2375.
    • (1999) J Immunol , vol.162 , pp. 2375
    • Randolph, D.A.1    Carruthers, C.J.2    Szabo, S.J.3    Murphy, K.M.4    Chaplin, D.D.5
  • 45
    • 0033230302 scopus 로고    scopus 로고
    • T helper 1 cells and interferon gamma regulate allergic airway inflammation and mucus production
    • Cohn L, Homer RJ, Niu N, Bottomly K. T helper 1 cells and interferon gamma regulate allergic airway inflammation and mucus production. J Exp Med 1999 190: 1309 18.
    • (1999) J Exp Med , vol.190 , pp. 1309-18
    • Cohn, L.1    Homer, R.J.2    Niu, N.3    Bottomly, K.4
  • 46
    • 0025640951 scopus 로고
    • Vascular beds in the airways of normal subjects and asthmatics
    • Laitinen A, Laitinen LA. Vascular beds in the airways of normal subjects and asthmatics. Eur Respir J 1990 12: 658s 62s.
    • (1990) Eur Respir J , vol.12
    • Laitinen, A.1    Laitinen, L.A.2
  • 47
    • 0026708571 scopus 로고
    • Vascular factors in bronchial hyperresponsiveness and asthma
    • Regnard J, Lockhart A. Vascular factors in bronchial hyperresponsiveness and asthma. Respir Med 1992 86: 179 81.
    • (1992) Respir Med , vol.86 , pp. 179-81
    • Regnard, J.1    Lockhart, A.2
  • 49
    • 0036799278 scopus 로고    scopus 로고
    • Function of the serotonin 5-hydroxytryptamine 2B receptor in pulmonary hypertension
    • Launay JM, Herve P, Peoc'h K et al. Function of the serotonin 5-hydroxytryptamine 2B receptor in pulmonary hypertension. Nat Med 2002 8: 1129 35.
    • (2002) Nat Med , vol.8 , pp. 1129-35
    • Launay, J.M.1    Herve, P.2    Peoc'H, K.3
  • 50
    • 0030476382 scopus 로고    scopus 로고
    • Targeted expression of IL-11 in the murine airway causes lymphocytic inflammation, bronchial remodeling, and airways obstruction
    • Tang W, Geba GP, Zheng T et al. Targeted expression of IL-11 in the murine airway causes lymphocytic inflammation, bronchial remodeling, and airways obstruction. J Clin Invest 1996 98: 2845 53.
    • (1996) J Clin Invest , vol.98 , pp. 2845-53
    • Tang, W.1    Geba, G.P.2    Zheng, T.3
  • 51
    • 0041829207 scopus 로고    scopus 로고
    • TGF-beta1 causes airway fibrosis and increased collagen I and III mRNA in mice
    • Kenyon NJ, Ward RW, Mcgrew G, Last JA. TGF-beta1 causes airway fibrosis and increased collagen I and III mRNA in mice. Thorax 2003 58: 772 7.
    • (2003) Thorax , vol.58 , pp. 772-7
    • Kenyon, N.J.1    Ward, R.W.2    McGrew, G.3    Last, J.A.4
  • 52
    • 85047693288 scopus 로고    scopus 로고
    • Inhibition of airway remodeling in IL-5-deficient mice
    • Cho JY, Miller M, Baek KJ et al. Inhibition of airway remodeling in IL-5-deficient mice. J Clin Invest 2004 113: 551 60.
    • (2004) J Clin Invest , vol.113 , pp. 551-60
    • Cho, J.Y.1    Miller, M.2    Baek, K.J.3
  • 53
    • 0035724451 scopus 로고    scopus 로고
    • IL-5 deficiency abolishes aspects of airway remodelling in a murine model of lung inflammation
    • Trifilieff A, Fujitani Y, Coyle AJ, Kopf M, Bertrand C. IL-5 deficiency abolishes aspects of airway remodelling in a murine model of lung inflammation. Clin Exp Allergy 2001 31: 934 42.
    • (2001) Clin Exp Allergy , vol.31 , pp. 934-42
    • Trifilieff, A.1    Fujitani, Y.2    Coyle, A.J.3    Kopf, M.4    Bertrand, C.5
  • 54
    • 33646857548 scopus 로고    scopus 로고
    • The histamine H4 receptor mediates allergic airway inflammation by regulating the activation of CD4+T cells
    • Dunford PJ, O'Donnell N, Riley JP, Williams KN, Karlsson L, Thurmond RL. The histamine H4 receptor mediates allergic airway inflammation by regulating the activation of CD4+T cells. J Immunol 2006 176: 7062 70.
    • (2006) J Immunol , vol.176 , pp. 7062-70
    • Dunford, P.J.1    O'Donnell, N.2    Riley, J.P.3    Williams, K.N.4    Karlsson, L.5    Thurmond, R.L.6
  • 57
    • 33646901630 scopus 로고    scopus 로고
    • The role of the mast cell in the pathophysiology of asthma
    • Bradding P, Walls AF, Holgate ST. The role of the mast cell in the pathophysiology of asthma. J Allergy Clin Immunol 2006 117: 1277 84.
    • (2006) J Allergy Clin Immunol , vol.117 , pp. 1277-84
    • Bradding, P.1    Walls, A.F.2    Holgate, S.T.3
  • 58
    • 0032927413 scopus 로고    scopus 로고
    • Cord blood-derived cultured human mast cells produce transforming growth factor beta1
    • Kanbe N, Kurosawa M, Nagata H, Saito H, Miyachi T. Cord blood-derived cultured human mast cells produce transforming growth factor beta1. Clin Exp Allergy 1999 29: 105 13.
    • (1999) Clin Exp Allergy , vol.29 , pp. 105-13
    • Kanbe, N.1    Kurosawa, M.2    Nagata, H.3    Saito, H.4    Miyachi, T.5
  • 59
    • 0033049944 scopus 로고    scopus 로고
    • Immunohistochemical localisation of the matrix metalloproteinases MMP-3 and MMP-9 within the airways in asthma
    • Dahlen B, Shute J, Howarth P. Immunohistochemical localisation of the matrix metalloproteinases MMP-3 and MMP-9 within the airways in asthma. Thorax 1999 54: 590 6.
    • (1999) Thorax , vol.54 , pp. 590-6
    • Dahlen, B.1    Shute, J.2    Howarth, P.3
  • 60
    • 0038240898 scopus 로고    scopus 로고
    • Mast cells play a partial role in allergen-induced subepithelial fibrosis in a murine model of allergic asthma
    • Masuda T, Tanaka H, Komai M et al. Mast cells play a partial role in allergen-induced subepithelial fibrosis in a murine model of allergic asthma. Clin Exp Allergy 2003 33: 705 13.
    • (2003) Clin Exp Allergy , vol.33 , pp. 705-13
    • Masuda, T.1    Tanaka, H.2    Komai, M.3
  • 61
    • 33745225217 scopus 로고    scopus 로고
    • Mast cells can promote the development of multiple features of chronic asthma in mice
    • Yu M, Tsai M, Tam SY, Jones C, Zehnder J, Galli SJ. Mast cells can promote the development of multiple features of chronic asthma in mice. J Clin Invest 2006 116: 1633 41.
    • (2006) J Clin Invest , vol.116 , pp. 1633-41
    • Yu, M.1    Tsai, M.2    Tam, S.Y.3    Jones, C.4    Zehnder, J.5    Galli, S.J.6
  • 62
    • 0037308329 scopus 로고    scopus 로고
    • The role of the mast cell in asthma: A reassessment
    • Bradding P. The role of the mast cell in asthma: a reassessment. Curr Opin Allergy Clin Immunol 2003 3: 45 50.
    • (2003) Curr Opin Allergy Clin Immunol , vol.3 , pp. 45-50
    • Bradding, P.1
  • 63
    • 0024348298 scopus 로고
    • Heterogeneity of mast cells and phenotypic change between subpopulations
    • Kitamura Y. Heterogeneity of mast cells and phenotypic change between subpopulations. Ann Rev Immunol 1989 7: 59 66.
    • (1989) Ann Rev Immunol , vol.7 , pp. 59-66
    • Kitamura, Y.1
  • 64
    • 0025855213 scopus 로고
    • CD4-mediated stimulation of human eosinophils: Lymphocyte chemoattractant factor and other CD4-binding ligand elicit eosinophil migration
    • Rand TH, Cruikshank WW, Center DM, Weller PF. CD4-mediated stimulation of human eosinophils: lymphocyte chemoattractant factor and other CD4-binding ligand elicit eosinophil migration. J Exp Med 1991 173: 1521 8.
    • (1991) J Exp Med , vol.173 , pp. 1521-8
    • Rand, T.H.1    Cruikshank, W.W.2    Center, D.M.3    Weller, P.F.4
  • 66
    • 4644223322 scopus 로고    scopus 로고
    • Cutting edge: Serotonin is a chemotactic factor for eosinophils and functions additively with eotaxin
    • Boehme SA, Lio FM, Sikora L et al. Cutting edge: serotonin is a chemotactic factor for eosinophils and functions additively with eotaxin. J Immunol 2004 173: 3599 603.
    • (2004) J Immunol , vol.173 , pp. 3599-603
    • Boehme, S.A.1    Lio, F.M.2    Sikora, L.3
  • 67
    • 0028918920 scopus 로고
    • Serotonin regulation of T-cell subpopulations and of macrophage accessory function
    • Young MR, Matthews JP. Serotonin regulation of T-cell subpopulations and of macrophage accessory function. Immunology 1995 84: 148 52.
    • (1995) Immunology , vol.84 , pp. 148-52
    • Young, M.R.1    Matthews, J.P.2
  • 68
    • 31544457592 scopus 로고    scopus 로고
    • A novel form of immune signaling revealed by transmission of the inflammatory mediator serotonin between dendritic cells and T cells
    • O'Connell PJ, Wang X, Leon-Ponte M, Griffiths C, Pingle SC, Ahern GP. A novel form of immune signaling revealed by transmission of the inflammatory mediator serotonin between dendritic cells and T cells. Blood 2006 107: 1010 7.
    • (2006) Blood , vol.107 , pp. 1010-7
    • O'Connell, P.J.1    Wang, X.2    Leon-Ponte, M.3    Griffiths, C.4    Pingle, S.C.5    Ahern, G.P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.