메뉴 건너뛰기




Volumn 41, Issue SUPPL. 1, 2007, Pages

Bacteria in Crohn's disease: Mechanisms of inflammation and therapeutic implications

Author keywords

Crohn's; Organisms

Indexed keywords

BACTERIAL FLORA; BACTERICIDAL ACTIVITY; BACTERIUM; BACTEROIDES THETAIOTAOMICRON; BACTEROIDES VULGATUS; BIFIDOBACTERIUM; CELLULAR IMMUNITY; CROHN DISEASE; DIET; ENTEROBACTERIACEAE; ENTEROCOCCUS FAECALIS; ESCHERICHIA COLI; FUSOBACTERIUM VARIUM; GENETIC SUSCEPTIBILITY; HELICOBACTER; HUMAN; HYGIENE; IMMUNE RESPONSE; IMMUNOREGULATION; IMMUNOSUPPRESSIVE TREATMENT; INFECTION RESISTANCE; INFECTION SENSITIVITY; INFLAMMATION; KLEBSIELLA PNEUMONIAE; LACTOBACILLUS; MUCOSAL IMMUNITY; MYCOBACTERIUM PARATUBERCULOSIS; NONHUMAN; PERSISTENT INFECTION; PRIORITY JOURNAL; REVIEW; SACCHAROMYCES BOULARDII;

EID: 34247243350     PISSN: 01920790     EISSN: None     Source Type: Journal    
DOI: 10.1097/MCG.0b013e31802db364     Document Type: Review
Times cited : (45)

References (45)
  • 1
    • 0038739853 scopus 로고    scopus 로고
    • Natural biota of the human gastrointestinal tract
    • Blaser MJ, Smith PD, Ravdin JI, et al. eds, Philadelphia: Lippincott Williams & Wilkins;
    • Wilson KH. Natural biota of the human gastrointestinal tract. In: Blaser MJ, Smith PD, Ravdin JI, et al. eds. Infections of the Gastrointestinal Tract. Philadelphia: Lippincott Williams & Wilkins; 2002.
    • (2002) Infections of the Gastrointestinal Tract
    • Wilson, K.H.1
  • 2
    • 33744804299 scopus 로고    scopus 로고
    • Metagenomic analysis of the human distal gut microbiome
    • Gill SR, Pop M, Deboy RT, et al. Metagenomic analysis of the human distal gut microbiome. Science. 2006;312:1355-1359.
    • (2006) Science , vol.312 , pp. 1355-1359
    • Gill, S.R.1    Pop, M.2    Deboy, R.T.3
  • 3
    • 20544444045 scopus 로고    scopus 로고
    • Diversity of the human intestinal microbial flora
    • Eckburg PB, Bik EM, Bernstein CN, et al. Diversity of the human intestinal microbial flora. Science. 2005;308:1635-1638.
    • (2005) Science , vol.308 , pp. 1635-1638
    • Eckburg, P.B.1    Bik, E.M.2    Bernstein, C.N.3
  • 4
    • 2442524857 scopus 로고    scopus 로고
    • Microbial influences in inflammatory bowel disease: Role in pathogenesis and clinical implications
    • Sartor RB, Sandborn WJ, eds, Edinborough: Elsevier Publishers;
    • Sartor RB. Microbial influences in inflammatory bowel disease: role in pathogenesis and clinical implications. In: Sartor RB, Sandborn WJ, eds. Kirsner's Inflammatory Bowel Diseases. Edinborough: Elsevier Publishers; 2004.
    • (2004) Kirsner's Inflammatory Bowel Diseases
    • Sartor, R.B.1
  • 5
    • 33745775434 scopus 로고    scopus 로고
    • Mechanisms of disease: Pathogenesis of Crohn's disease and ulcerative colitis
    • Sartor RB. Mechanisms of disease: pathogenesis of Crohn's disease and ulcerative colitis. Nat Clin Pract Gastroenterol Hepatol. 2006;3:390-407.
    • (2006) Nat Clin Pract Gastroenterol Hepatol , vol.3 , pp. 390-407
    • Sartor, R.B.1
  • 6
    • 21044455876 scopus 로고    scopus 로고
    • Does Mycobacterium avium subspecies paratuberculosis cause Crohn's disease?
    • Sartor RB. Does Mycobacterium avium subspecies paratuberculosis cause Crohn's disease? Gut. 2005;54:896-898.
    • (2005) Gut , vol.54 , pp. 896-898
    • Sartor, R.B.1
  • 7
    • 0037173488 scopus 로고    scopus 로고
    • Pasteurization of milk and the heat resistance of Mycobacterium avium subsp. paratuberculosis: A critical review of the data
    • Lund BM, Gould GW, Rampling AM. Pasteurization of milk and the heat resistance of Mycobacterium avium subsp. paratuberculosis: a critical review of the data. Int J Food Microbiol. 2002;77:135-145.
    • (2002) Int J Food Microbiol , vol.77 , pp. 135-145
    • Lund, B.M.1    Gould, G.W.2    Rampling, A.M.3
  • 9
    • 0034075091 scopus 로고    scopus 로고
    • Isolation of Mycobacterium avium subsp paratuberculosis from breast milk of Crohn's disease patients
    • Naser SA, Schwartz D, Shafran I. Isolation of Mycobacterium avium subsp paratuberculosis from breast milk of Crohn's disease patients. Am J Gastroenterol. 2000;95:1094-1095.
    • (2000) Am J Gastroenterol , vol.95 , pp. 1094-1095
    • Naser, S.A.1    Schwartz, D.2    Shafran, I.3
  • 10
    • 4544279029 scopus 로고    scopus 로고
    • Culture of Mycobacterium avium subspecies paratuberculosis from the blood of patients with Crohn's disease
    • Naser SA, Ghobrial G, Romero C, et al. Culture of Mycobacterium avium subspecies paratuberculosis from the blood of patients with Crohn's disease. Lancet. 2004;364:1039-1044.
    • (2004) Lancet , vol.364 , pp. 1039-1044
    • Naser, S.A.1    Ghobrial, G.2    Romero, C.3
  • 11
    • 33745772695 scopus 로고    scopus 로고
    • Bacterial-aluminum interactions. The role of aluminum in bacterial-induced colitis in IL-10 deficient mice
    • Lerner A, Eluri S, Perl D, et al. Bacterial-aluminum interactions. The role of aluminum in bacterial-induced colitis in IL-10 deficient mice. Gastroenterology. 2006;130:A362.
    • (2006) Gastroenterology , vol.130
    • Lerner, A.1    Eluri, S.2    Perl, D.3
  • 12
    • 33745773377 scopus 로고    scopus 로고
    • Effect of diet on colitis in IL-10-/- mice
    • Tsang J, Sartor RB. Effect of diet on colitis in IL-10-/- mice. Gastroenterology. 2005;128:A210.
    • (2005) Gastroenterology , vol.128
    • Tsang, J.1    Sartor, R.B.2
  • 13
    • 34247195317 scopus 로고    scopus 로고
    • A high sucrose diet exacerbates immune-mediated colitis in IL-10 deficient mice
    • Lee K, Sartor RB. A high sucrose diet exacerbates immune-mediated colitis in IL-10 deficient mice. Gastroenterology. 2006;130:A350.
    • (2006) Gastroenterology , vol.130
    • Lee, K.1    Sartor, R.B.2
  • 14
    • 2442453484 scopus 로고    scopus 로고
    • Therapeutic manipulation of the enteric microflora in inflammatory bowel diseases: Antibiotics, probiotics and prebiotics
    • Sartor RB. Therapeutic manipulation of the enteric microflora in inflammatory bowel diseases: antibiotics, probiotics and prebiotics. Gastroenterology. 2004;126:1620-1633.
    • (2004) Gastroenterology , vol.126 , pp. 1620-1633
    • Sartor, R.B.1
  • 15
    • 13244275284 scopus 로고    scopus 로고
    • Probiotic therapy of intestinal inflammation and infections
    • Sartor RB. Probiotic therapy of intestinal inflammation and infections. Curr Opinion Gastroenterol. 2005;21:44-50.
    • (2005) Curr Opinion Gastroenterol , vol.21 , pp. 44-50
    • Sartor, R.B.1
  • 16
    • 33751118010 scopus 로고    scopus 로고
    • Prostaglandin-mediated inhibition of Na+/H+ exchanger isoform 2 stimulates recovery of barrier function in ischemia-injured intestine
    • Moeser AJ, Nighot PK, Ryan KA, et al. Prostaglandin-mediated inhibition of Na+/H+ exchanger isoform 2 stimulates recovery of barrier function in ischemia-injured intestine. Am J Physiol Gastrointest Liver Physiol. 2006;291:G885-G894.
    • (2006) Am J Physiol Gastrointest Liver Physiol , vol.291
    • Moeser, A.J.1    Nighot, P.K.2    Ryan, K.A.3
  • 17
    • 33646349207 scopus 로고    scopus 로고
    • Wound-induced p38 MAPK-dependent histone H3 phosphorylation correlates with increased COX-2 expression in enterocytes
    • Karrasch T, Steinbrecher KA, Allard B, et al. Wound-induced p38 MAPK-dependent histone H3 phosphorylation correlates with increased COX-2 expression in enterocytes. J Cell Physiol. 2006;207:809-815.
    • (2006) J Cell Physiol , vol.207 , pp. 809-815
    • Karrasch, T.1    Steinbrecher, K.A.2    Allard, B.3
  • 18
    • 17744373329 scopus 로고    scopus 로고
    • Genetics of Crohn's disease, an archetypal inflammatory barrier disease
    • Schreiber S, Rosenstiel P, Albrecht M, et al. Genetics of Crohn's disease, an archetypal inflammatory barrier disease. Nat Rev Genet. 2005;6:376-388.
    • (2005) Nat Rev Genet , vol.6 , pp. 376-388
    • Schreiber, S.1    Rosenstiel, P.2    Albrecht, M.3
  • 19
    • 0037380969 scopus 로고    scopus 로고
    • CARD15/NOD2 functions as an anti-bacterial factor in human intestinal epithelial cells
    • Hisamatsu T, Suzuki M, Reinecker HC, et al. CARD15/NOD2 functions as an anti-bacterial factor in human intestinal epithelial cells. Gastroenterology. 2003;124:993-1000.
    • (2003) Gastroenterology , vol.124 , pp. 993-1000
    • Hisamatsu, T.1    Suzuki, M.2    Reinecker, H.C.3
  • 20
    • 29144483937 scopus 로고    scopus 로고
    • Reduced Paneth cell alpha-defensins in ileal Crohn's disease
    • Wehkamp J, Salzman NH, Porter E, et al. Reduced Paneth cell alpha-defensins in ileal Crohn's disease. Proc Natl Acad Sci U S A. 2005;102:18129-18134.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 18129-18134
    • Wehkamp, J.1    Salzman, N.H.2    Porter, E.3
  • 21
    • 4444253690 scopus 로고    scopus 로고
    • NOD2 is a negative regulator of toll-like receptor 2-mediated T helper type 1 responses
    • Watanabe T, Kitani A, Murray PJ, et al. NOD2 is a negative regulator of toll-like receptor 2-mediated T helper type 1 responses. Nat Immunol. 2004;5:800-808.
    • (2004) Nat Immunol , vol.5 , pp. 800-808
    • Watanabe, T.1    Kitani, A.2    Murray, P.J.3
  • 22
    • 0038109983 scopus 로고    scopus 로고
    • Crohn's disease and the NOD2 gene: A role for paneth cells
    • Lala S, Ogura Y, Osborne C, et al. Crohn's disease and the NOD2 gene: a role for paneth cells. Gastroenterology. 2003;125:47-57.
    • (2003) Gastroenterology , vol.125 , pp. 47-57
    • Lala, S.1    Ogura, Y.2    Osborne, C.3
  • 24
    • 13244292161 scopus 로고    scopus 로고
    • Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract
    • Kobayashi KS, Chamaillard M, Ogura Y, et al. Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract. Science. 2005;307:731-734.
    • (2005) Science , vol.307 , pp. 731-734
    • Kobayashi, K.S.1    Chamaillard, M.2    Ogura, Y.3
  • 25
    • 0029586031 scopus 로고
    • Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD)
    • Duchmann R, Kaiser I, Hermann E, et al. Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD). Clin Exp Immunol. 1995;102:448-455.
    • (1995) Clin Exp Immunol , vol.102 , pp. 448-455
    • Duchmann, R.1    Kaiser, I.2    Hermann, E.3
  • 27
    • 34247193945 scopus 로고    scopus 로고
    • Experimental models of mucosal inflammation
    • Strober W, Fuss IJ. Experimental models of mucosal inflammation. Adv Exp Med Biol. 2006;579:55-97.
    • (2006) Adv Exp Med Biol , vol.579 , pp. 55-97
    • Strober, W.1    Fuss, I.J.2
  • 28
    • 0034957289 scopus 로고    scopus 로고
    • Decreased Bax expression by mucosal T cells favours resistance to apoptosis in Crohn's disease
    • Itoh J, de La MC, Strong SA, et al. Decreased Bax expression by mucosal T cells favours resistance to apoptosis in Crohn's disease. Gut. 2001;49:35-41.
    • (2001) Gut , vol.49 , pp. 35-41
    • Itoh, J.D.L.M.1    Strong, S.A.2
  • 29
    • 23244455992 scopus 로고    scopus 로고
    • Interleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis, and cell restitution
    • Heller F, Florian P, Bojarski C, et al. Interleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis, and cell restitution. Gastroenterology. 2005;129:550-564.
    • (2005) Gastroenterology , vol.129 , pp. 550-564
    • Heller, F.1    Florian, P.2    Bojarski, C.3
  • 30
    • 0028901664 scopus 로고
    • Immunocytochemical evidence of Listeria, Escherichia coli, and Streptococcus antigens in Crohn's disease
    • Liu Y, Van Kruiningen HJ, West AB, et al. Immunocytochemical evidence of Listeria, Escherichia coli, and Streptococcus antigens in Crohn's disease. Gastroenterology. 1995;108:1396-1404.
    • (1995) Gastroenterology , vol.108 , pp. 1396-1404
    • Liu, Y.1    Van Kruiningen, H.J.2    West, A.B.3
  • 31
    • 0031915148 scopus 로고    scopus 로고
    • Early lesions of recurrent Crohn's disease caused by infusion of intestinal contents in excluded ileum
    • D'Haens GR, Geboes K, Peeters M, et al. Early lesions of recurrent Crohn's disease caused by infusion of intestinal contents in excluded ileum. Gastroenterology. 1998;114:262-267.
    • (1998) Gastroenterology , vol.114 , pp. 262-267
    • D'Haens, G.R.1    Geboes, K.2    Peeters, M.3
  • 32
    • 10744228695 scopus 로고    scopus 로고
    • Association of antibody responses to microbial antigens and complications of small bowel Crohn's disease
    • Mow WS, Vasiliauskas EA, Lin YC, et al. Association of antibody responses to microbial antigens and complications of small bowel Crohn's disease. Gastroenterology. 2004;126:414-424.
    • (2004) Gastroenterology , vol.126 , pp. 414-424
    • Mow, W.S.1    Vasiliauskas, E.A.2    Lin, Y.C.3
  • 33
    • 0032412057 scopus 로고    scopus 로고
    • Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice
    • Sellon RK, Tonkonogy S, Schultz M, et al. Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice. Infect Immun. 1998;66:5224-5231.
    • (1998) Infect Immun , vol.66 , pp. 5224-5231
    • Sellon, R.K.1    Tonkonogy, S.2    Schultz, M.3
  • 34
    • 33745799164 scopus 로고    scopus 로고
    • Different host genetic backgrounds determine disease phenotypes induced by selective bacterial colonization
    • Kim SC, Tonkonogy SL, Albright CA, et al. Different host genetic backgrounds determine disease phenotypes induced by selective bacterial colonization. Gastroenterology. 2005;128:A512.
    • (2005) Gastroenterology , vol.128
    • Kim, S.C.1    Tonkonogy, S.L.2    Albright, C.A.3
  • 35
    • 33745799955 scopus 로고    scopus 로고
    • Dual-association of gnotobiotic IL-10-/- mice with two nonpathogenic commensal bacterial species accelerates colitis
    • Kim SC, Tonkonogy SL, Bower M, et al. Dual-association of gnotobiotic IL-10-/- mice with two nonpathogenic commensal bacterial species accelerates colitis. Gastroenterology. 2004;126:A291.
    • (2004) Gastroenterology , vol.126
    • Kim, S.C.1    Tonkonogy, S.L.2    Bower, M.3
  • 36
    • 2342646956 scopus 로고    scopus 로고
    • Bacterial flagellin is a dominant antigen in Crohn's disease
    • Lodes MJ, Cong Y, Elson CO, et al. Bacterial flagellin is a dominant antigen in Crohn's disease. J Clin Invest. 2004;113:1296-1306.
    • (2004) J Clin Invest , vol.113 , pp. 1296-1306
    • Lodes, M.J.1    Cong, Y.2    Elson, C.O.3
  • 37
    • 33244472793 scopus 로고    scopus 로고
    • Signalling pathways and molecular interactions of NOD1 and NOD2
    • Strober W, Murray PJ, Kitani A, et al. Signalling pathways and molecular interactions of NOD1 and NOD2. Nat Rev Immunol. 2006;6:9-20.
    • (2006) Nat Rev Immunol , vol.6 , pp. 9-20
    • Strober, W.1    Murray, P.J.2    Kitani, A.3
  • 38
    • 0030209985 scopus 로고    scopus 로고
    • Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5
    • Fuss IJ, Neurath M, Boirivant M, et al. Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5. J Immunol. 1996;157:1261-1270.
    • (1996) J Immunol , vol.157 , pp. 1261-1270
    • Fuss, I.J.1    Neurath, M.2    Boirivant, M.3
  • 39
    • 0037216498 scopus 로고    scopus 로고
    • Increased expression of interleukin 17 in inflammatory bowel disease
    • Fujino S, Andoh A, Bamba S, et al. Increased expression of interleukin 17 in inflammatory bowel disease. Gut. 2003;52:65-70.
    • (2003) Gut , vol.52 , pp. 65-70
    • Fujino, S.1    Andoh, A.2    Bamba, S.3
  • 40
    • 0036883901 scopus 로고    scopus 로고
    • Bacterial-reactive T regulatory cells inhibit pathogenic immune responses to the enteric flora
    • Cong Y, Weaver CT, Lazenby A, et al. Bacterial-reactive T regulatory cells inhibit pathogenic immune responses to the enteric flora. J Immunol. 2002;169:6112-6119.
    • (2002) J Immunol , vol.169 , pp. 6112-6119
    • Cong, Y.1    Weaver, C.T.2    Lazenby, A.3
  • 41
    • 0025887808 scopus 로고
    • Double blind, placebo controlled trial of metronidazole in Crohn's disease
    • Sutherland L, Singleton J, Sessions J, et al. Double blind, placebo controlled trial of metronidazole in Crohn's disease. Gut. 1991;32:1071-1075.
    • (1991) Gut , vol.32 , pp. 1071-1075
    • Sutherland, L.1    Singleton, J.2    Sessions, J.3
  • 42
    • 0036305494 scopus 로고    scopus 로고
    • Combined budesonide and antibiotic therapy for active Crohn's disease: A randomized controlled trial
    • Steinhart AH, Feagan BG, Wong CJ, et al. Combined budesonide and antibiotic therapy for active Crohn's disease: a randomized controlled trial. Gastroenterology. 2002;123:33-40.
    • (2002) Gastroenterology , vol.123 , pp. 33-40
    • Steinhart, A.H.1    Feagan, B.G.2    Wong, C.J.3
  • 43
    • 0033860601 scopus 로고    scopus 로고
    • Oral bacteriotherapy as maintenance treatment in patients with chronic pouchitis: A doubleblind, placebo-controlled trial
    • Gionchetti P, Rizzello F, Venturi A, et al. Oral bacteriotherapy as maintenance treatment in patients with chronic pouchitis: a doubleblind, placebo-controlled trial. Gastroenterology. 2000;119:305-309.
    • (2000) Gastroenterology , vol.119 , pp. 305-309
    • Gionchetti, P.1    Rizzello, F.2    Venturi, A.3
  • 44
    • 4644239296 scopus 로고    scopus 로고
    • Maintaining remission of ulcerative colitis with the probiotic Escherichia coli Nissle 1917 is as effective as with standard mesalazine
    • Kruis W, Fric P, Pokrotnieks J, et al. Maintaining remission of ulcerative colitis with the probiotic Escherichia coli Nissle 1917 is as effective as with standard mesalazine. Gut. 2004;53:1617-1623.
    • (2004) Gut , vol.53 , pp. 1617-1623
    • Kruis, W.1    Fric, P.2    Pokrotnieks, J.3
  • 45
    • 0037371185 scopus 로고    scopus 로고
    • Lactobacillus GG prevents recurrence of colitis in HLA-B27 transgenic rats after antibiotic treatment
    • Dieleman LA, Goerres M, Arends A, et al. Lactobacillus GG prevents recurrence of colitis in HLA-B27 transgenic rats after antibiotic treatment. Gut. 2003;52:370-376.
    • (2003) Gut , vol.52 , pp. 370-376
    • Dieleman, L.A.1    Goerres, M.2    Arends, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.