A novel lumazine synthase inhibitor derived from oxidation of 1,3,6,8-tetrahydroxy-2,7-naphthyridine to a tetraazaperylenehexaone derivative

Journal of Organic Chemistry

Volumn 72, Issue 8, 2007, Pages 2769-2776

  Zhang, Yanlei ^a   Illarionov, Boris ^b   Bacher, Adelbert ^b   Fischer, Markus ^b   George, Gunda I ^c   Ye, Qi Zhuang ^c   Vander Velde, David ^c   Fanwick, Phillip E ^d   Song, Yunlong ^a   Cushman, Mark ^a  

^a PURDUE UNIVERSITY   (United States)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c UNIVERSITY OF KANSAS   (United States)

^d PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OXIDATIVE PHENOLIC COUPLING; ROOM TEMPERATURE; SCHIZOSACCHAROMYCES POMBE LUMAZINE SYNTHASE; SYNTHASE INHIBITORS;

DERIVATIVES; OXIDATION; SOLID STATE REACTIONS; X RAY CRYSTALLOGRAPHY;

ENZYME INHIBITION;

1,3,6,8 TETRAHYDROXY 2,7 NAPHTHYRIDINE; 2,5,8,11 TETRAAZA 5,11 DIHYDRO 4,10 DIHYDROXYPERYLENE 1,3,6,7,9,12 HEXAONE; ENZYME INHIBITOR; FUNGAL ENZYME; LUMAZINE; NAPHTHYRIDINE DERIVATIVE; PERYLENE; UNCLASSIFIED DRUG;

AB INITIO CALCULATION; ARTICLE; COMPETITIVE INHIBITION; ENANTIOMER; ENZYME INHIBITION; HIGH THROUGHPUT SCREENING; NONHUMAN; OXIDATION; ROOM TEMPERATURE; SCHIZOSACCHAROMYCES POMBE; X RAY CRYSTALLOGRAPHY;

AZA COMPOUNDS; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; HETEROCYCLIC COMPOUNDS; KINETICS; MOLECULAR STRUCTURE; MULTIENZYME COMPLEXES; NAPHTHYRIDINES; OXIDATION-REDUCTION; PERYLENE; PHENOL; SCHIZOSACCHAROMYCES;

EID: 34247234631     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo062246d     Document Type: Article

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