Investigation of the binding of fluorolumazines to the 1-MDa capsid of lumazine synthase by 15N{19F} REDOR NMR

Journal of the American Chemical Society

Volumn 121, Issue 33, 1999, Pages 7500-7508

  Goetz, Jon M ^a   Poliks, Barbara ^b   Studelska, Daniel R ^a   Fischer, Markus ^c   Kugelbrey, Karl ^c   Bacher, Adelbert ^c   Cushman, Mark ^d   Schaefer, Jacob ^a  

^a WASHINGTON UNIVERSITY   (United States)

^b BINGHAMTON UNIVERSITY   (United States)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^d PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUOROLUMAZINE DERIVATIVE; LUMAZINE SYNTHASE; RIBOFLAVIN SYNTHASE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CATALYSIS; COMPLEX FORMATION; DRUG SYNTHESIS;

EID: 0033603892     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja983792u     Document Type: Article

References (32)

1. Plaut, G. W. E; Smith, C. M.; Alworth, W. L. Annu. Rev. Biochem. 1974, 43, 899-922.
2. Plaut, G. W. E. In Comprehensive Biochemistry; Florkin M., Stotz, E. H., Eds.; Elsevier: Amsterdam, 1971; Vol. 21, pp 11-45.
3. Brown, G. M.; Williamson, J. M. In Escherichia coli and Salmonella typhimurium; Neidhardt, F. C., Ingraham, J. L., Low, K. B., Magasanik, B., Schaechter, M., Umbarger, H. E., Eds.; American Society for Microbiology: Washington, DC, 1987; p 521.
4. Bacher, A.; Ladenstein, R. In Chemistry and Biochemistry of Flavoenzymes; Müller, F., Ed.; Chemical Rubber Co.: Boca Raton, FL, 1991; Vol. II, pp 293-316.
5. Bacher, A.; Fischer, M.; Kis, K.; Kugelbrey, K.; Mörtl, S.; Scheuring, J.; Weinkauf, S.; Eberhardt, S.; Schmidt-Bäse, K.; Huber, R.; Ritsert, K.; Cushman, M.; Ladenstein, R. Biochem. Soc. Trans. 1996, 24, 89-94.
6. Kis, K.; Volk, R.; Bacher, A. Biochemistry 1995, 34, 2883-2892.
7. Kis, K.; Bacher, A. J. Biol. Chem. 1995, 270, 16788-16795.
8. Ladenstein, R.; Schneider, M.; Huber, R.; Bartunik, H. D.; Wilson, K.; Schott, K.; Bacher, A. J. Mol. Biol. 1988, 203, 1045-1070.
9. Bacher, A.; Eisenreich, W.; Kis, K.; Ladenstein, R.; Richter, G.; Scheuring, J.; Weinkauf, S. In Bioorganic Chemistry Frontiers; Dugas, H., Schmidtchen, F. P., Eds.; Springer-Verlag: Berlin, 1993; Vol. 3, pp 147-192.
10. Ritsert, K.; Huber, R.; Turk, D.; Ladenstein, R.; Schmidt-Bäse, K.; Bacher, A. J. Mol. Biol. 1995, 253, 151-167.
11. Bacher, A.; Ludwig, H. C.; Schnepple, H.; Ben-Shaul, Y. J. Mol. Biol. 1986, 187, 75-86.
12. Ladenstein, R.; Meyer, B.; Huber, R.; Labischinski, H.; Bartels, K.; Bartunik, H.-D.; Bachman, L.; Ludwig, H. C.; Bacher, A. J. Mol. Biol. 1986, 187, 87-100.
13. Ladenstein, R.; Ritsert, K.; Richter, G.; Bacher, A. Eur. J. Biochem. 1994, 223, 1007-1017.
14. Gullion, T.; Schaefer, J. J. Magn. Reson. 1989, 81, 196-200.
15. Gullion, T.; Schaefer, J. Adv. Magn. Reson. 1989, 13, 57-81.
16. Wang, J.; Balazs, Y. S.; Thompson, L. K. Biochemistry 1997, 36, 1699-1703.
17. Garbow, J. R.; Breslav, M.; Antohi, O.; Naider, F. Biochemistry 1994, 33, 10094-10099.
18. Li, Y.; Appleyard, R. J.; Shuttleworth, W. A.; Evans, J. N. S. J. Am. Chem. Soc. 1994, 116, 10799-10800.
19. Jakeman, D. L.; Mitchell, D. J.; Shuttleworth, W. A.; Evans, J. N. S. Biochemistry 1998, 37, 12012-12019.
20. Michal, C. A.; Jelinski, L. W. J. Biomol. NMR 1998, 12, 231-241.
21. Hing, A. W.; Tjandra, N.; Cottam, R. F.; Schaefer, J.; Ho, C. Biochemistry 1994, 33, 8651-8661.
22. Volk, R.; Bacher, A. J. Am. Chem. Soc. 1988, 110, 3651-3653.
23. Cushman, M.; Mavandadi, F.; Kugelbrey, K.; Bacher, A. Bioorg. Med. Chem. 1998, 6, 409-415.
24. Cushman, M.; Mavandadi, F.; Kugelbrey, K.; Bacher, A. J. Org. Chem. 1998, 62, 88944-8947.
25. Beach, R. L.; Plaut, G. W. E. J. Am. Chem. Soc. 1970, 92, 2913-2916.
26. Paterson, T.; Wood, H. C. S. J. Chem. Soc., Chem. Commun. 1969, 290-291.
27. Cushman, M.; Patel, H.; Scheuring, J.; Bacher, A. J. Org. Chem. 1992, 57, 5630-5643.
28. Cushman, M.; Patrick, D. A.; Bacher, A.; Scheuring, J. J. Org. Chem. 1991, 56, 4603-4608.
29. Scheuring, J.; Cushman, M.; Bacher, A. J. Org. Chem. 1995, 60, 243-245.
30. Studelska, D. R.; McDowell, L. M.; Espe, M. P.; Klag, C. A.; Schaefer, J. Biochemistry 1997, 36, 15555-15560.
31. Cushman, M.; Mihalic, J. T.; Kis, K.; Bacher, A. J. Org. Chem. 1999, 64, 3838-3845.
32. Bacher, A.; Eberhardt, S.; Fischer, M.; Mörtl, S.; Kis, K.; Kugelbrey, K.; Scheuring, J. In Methods Enzymology; McCormick, D. B., Suttie, J. W., Wagner, C., Eds.; Academic Press: San Diego, 1997; Vol. 280, pp 389-399.