SCOPUS 정보 검색 플랫폼

Volumn 67, Issue 16, 2002, Pages 5807-5816

Design, synthesis, and evaluation of 6-carboxyalkyl and 6-phosphonoxyalkyl derivatives of 7-oxo-8-ribitylaminolumazines as inhibitors of riboflavin synthase and lumazine synthase

(7) Cushman, Mark a Yang, Donglai a Gerhardt, Stefan b,c Huber, Robert c Fischer, Markus b Kis, Klaus b Bacher, Adelbert b

a PURDUE UNIVERSITY (United States)

b TECHNICAL UNIVERSITY OF MUNICH (Germany)

c MAX PLANCK INSTITUTE OF BIOCHEMISTRY (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING SITES;

BIOCHEMISTRY; DERIVATIVES; ENZYME KINETICS; ESCHERICHIA COLI; SYNTHESIS (CHEMICAL);

ENZYMES;

6 (2' CARBOXYETHYL) 7 OXOLUMAZINE; 6 (3' CARBOXYPROPYL) 7 OXO 8 (DEXTRO RIBITYL)LUMAZINE; 6 (3' CARBOXYPROPYL) 7 OXO 8 DEXTRO RIBITYLLUMAZINE; 7 OXO 6 (3 PHOSPHONOXYPROPYL) 8 (DEXTRO RIBITYL)LUMAZINE; 7 OXO 6 (4 PHOSPHONOXYBUTYL) 8 (DEXTRO RIBITYL)LUMAZINE; 7 OXO 8 RIBITYLAMINOLUMAZINE DERIVATIVE; BACTERIAL ENZYME; ENZYME INHIBITOR; LUMAZINE; LUMAZINE SYNTHASE; PURINE DERIVATIVE; RIBOFLAVIN SYNTHASE; UNCLASSIFIED DRUG;

ARTICLE; BACILLUS SUBTILIS; BINDING SITE; CHEMICAL STRUCTURE; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME INHIBITION; ESCHERICHIA COLI; HUMAN; MOLECULAR MODEL; PROTEIN BINDING; STRUCTURE ANALYSIS; SYNTHESIS;

BINDING SITES; DRUG DESIGN; ENZYME INHIBITORS; ESCHERICHIA COLI; KINETICS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MULTIENZYME COMPLEXES; PROTEIN CONFORMATION; PTERIDINES; RIBITOL; RIBOFLAVIN SYNTHASE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0037047544 PISSN: 00223263 EISSN: None Source Type: Journal
DOI: 10.1021/jo0201631 Document Type: Article

Times cited : (41)

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