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Volumn 120, Issue 5, 2007, Pages 388-397

Effective Pharmacologic Management of Alzheimer's Disease

Author keywords

Alzheimer's disease; Cholinesterase inhibitor; Donepezil; Galantamine; Management; Memantine; Pharmacotherapy; Rivastigmine

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; CHOLINESTERASE INHIBITOR; CITICOLINE; CYANOCOBALAMIN; DONEPEZIL; GALANTAMINE; GINKGO BILOBA EXTRACT; LEVACECARNINE; MELATONIN; MEMANTINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NONSTEROID ANTIINFLAMMATORY AGENT; PHOSPHATIDYLCHOLINE; PYRIDOXINE; RAZADYNE ER; RIVASTIGMINE; UNCLASSIFIED DRUG;

EID: 34247232644     PISSN: 00029343     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.amjmed.2006.08.036     Document Type: Review
Times cited : (197)

References (78)
  • 1
    • 14744292967 scopus 로고    scopus 로고
    • Long-term cholinesterase inhibitor therapy for Alzheimer's disease: practical considerations for the primary care physician
    • Geldmacher D.S. Long-term cholinesterase inhibitor therapy for Alzheimer's disease: practical considerations for the primary care physician. Prim Care Companion J Clin Psychiatry 5 (2003) 251-259
    • (2003) Prim Care Companion J Clin Psychiatry , vol.5 , pp. 251-259
    • Geldmacher, D.S.1
  • 2
    • 0030801772 scopus 로고    scopus 로고
    • Diagnosis and treatment of Alzheimer disease and related disorders. Consensus statement of the American Association for Geriatric Psychiatry, the Alzheimer's Association, and the American Geriatrics Society
    • Small G.W., Rabins P.V., Barry P.P., et al. Diagnosis and treatment of Alzheimer disease and related disorders. Consensus statement of the American Association for Geriatric Psychiatry, the Alzheimer's Association, and the American Geriatrics Society. JAMA 278 (1997) 1363-1371
    • (1997) JAMA , vol.278 , pp. 1363-1371
    • Small, G.W.1    Rabins, P.V.2    Barry, P.P.3
  • 3
    • 0030898844 scopus 로고    scopus 로고
    • Practice guideline for the treatment of patients with Alzheimer's disease and other dementias of late life
    • Practice guideline for the treatment of patients with Alzheimer's disease and other dementias of late life. Am J Psychiatry 154 5 Suppl (1997) 1-39
    • (1997) Am J Psychiatry , vol.154 , Issue.5 SUPPL , pp. 1-39
  • 4
    • 0035826771 scopus 로고    scopus 로고
    • Practice parameter: management of dementia (an evidence-based review). Report of the Quality Standards Subcommittee of the American Academy of Neurology
    • Doody R.S., Stevens J.C., Beck R.N., et al. Practice parameter: management of dementia (an evidence-based review). Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 56 (2001) 1154-1166
    • (2001) Neurology , vol.56 , pp. 1154-1166
    • Doody, R.S.1    Stevens, J.C.2    Beck, R.N.3
  • 5
    • 0037096921 scopus 로고    scopus 로고
    • Guidelines for managing Alzheimer's disease: part II. Treatment
    • Cummings J.L., Frank J.C., Cherry D., et al. Guidelines for managing Alzheimer's disease: part II. Treatment. Am Fam Physician 65 (2002) 2525-2534
    • (2002) Am Fam Physician , vol.65 , pp. 2525-2534
    • Cummings, J.L.1    Frank, J.C.2    Cherry, D.3
  • 6
    • 0036606398 scopus 로고    scopus 로고
    • Guidelines for managing Alzheimer's disease: part I. Assessment
    • Cummings J.L., Frank J.C., Cherry D., et al. Guidelines for managing Alzheimer's disease: part I. Assessment. Am Fam Physician 65 (2002) 2263-2272
    • (2002) Am Fam Physician , vol.65 , pp. 2263-2272
    • Cummings, J.L.1    Frank, J.C.2    Cherry, D.3
  • 7
    • 34247233133 scopus 로고    scopus 로고
    • Alzheimer's disease: risk stratification, patient evaluation, and outcome-effective pharmacologic therapy-year 2004 clinical update. Available at: http://www.ahcpub.com. Accessed June 9, 2005.
  • 8
    • 0035103036 scopus 로고    scopus 로고
    • Open-label, multicenter, phase 3 extension study of the safety and efficacy of donepezil in patients with Alzheimer disease
    • Doody R.S., Geldmacher D.S., Gordon B., Perdomo C.A., and Pratt R.D. Open-label, multicenter, phase 3 extension study of the safety and efficacy of donepezil in patients with Alzheimer disease. Arch Neurol 58 (2001) 427-433
    • (2001) Arch Neurol , vol.58 , pp. 427-433
    • Doody, R.S.1    Geldmacher, D.S.2    Gordon, B.3    Perdomo, C.A.4    Pratt, R.D.5
  • 9
    • 0033679259 scopus 로고    scopus 로고
    • A 52-week study of the efficacy of rivastigmine in patients with mild to moderately severe Alzheimer's disease
    • Farlow M.R., Anand R., Messina Jr. J., Hartman R., and Veach J. A 52-week study of the efficacy of rivastigmine in patients with mild to moderately severe Alzheimer's disease. Eur Neurol 44 (2000) 236-241
    • (2000) Eur Neurol , vol.44 , pp. 236-241
    • Farlow, M.R.1    Anand, R.2    Messina Jr., J.3    Hartman, R.4    Veach, J.5
  • 10
    • 0034720816 scopus 로고    scopus 로고
    • Galantamine in AD: a 6-month randomized, placebo-controlled trial with a 6-month extension
    • Raskind M.A., Peskind E.R., Wessel T., and Yuan W. Galantamine in AD: a 6-month randomized, placebo-controlled trial with a 6-month extension. Neurology 54 (2000) 2261-2268
    • (2000) Neurology , vol.54 , pp. 2261-2268
    • Raskind, M.A.1    Peskind, E.R.2    Wessel, T.3    Yuan, W.4
  • 11
    • 1042291157 scopus 로고    scopus 로고
    • The cognitive benefits of galantamine are sustained for at least 36 months: a long-term extension trial
    • Raskind M.A., Peskind E.R., Truyen L., Kershaw P., and Damaraju C.V. The cognitive benefits of galantamine are sustained for at least 36 months: a long-term extension trial. Arch Neurol 61 (2004) 252-256
    • (2004) Arch Neurol , vol.61 , pp. 252-256
    • Raskind, M.A.1    Peskind, E.R.2    Truyen, L.3    Kershaw, P.4    Damaraju, C.V.5
  • 14
    • 0345517106 scopus 로고    scopus 로고
    • Treatment of Alzheimer's disease: an evaluation of the cholinergic approach
    • Lemiere J., Van Gool D., and Dom R. Treatment of Alzheimer's disease: an evaluation of the cholinergic approach. Acta Neurol Belg 99 (1999) 96-106
    • (1999) Acta Neurol Belg , vol.99 , pp. 96-106
    • Lemiere, J.1    Van Gool, D.2    Dom, R.3
  • 15
    • 0036183539 scopus 로고    scopus 로고
    • Widely spread butyrylcholinesterase can hydrolyze acetylcholine in the normal and Alzheimer brain
    • Mesulam M., Guillozet A., Shaw P., and Quinn B. Widely spread butyrylcholinesterase can hydrolyze acetylcholine in the normal and Alzheimer brain. Neurobiol Dis 9 (2002) 88-93
    • (2002) Neurobiol Dis , vol.9 , pp. 88-93
    • Mesulam, M.1    Guillozet, A.2    Shaw, P.3    Quinn, B.4
  • 16
    • 0036363671 scopus 로고    scopus 로고
    • Advances in the treatment of Alzheimer's disease: benefits of dual cholinesterase inhibition
    • Ballard C.G. Advances in the treatment of Alzheimer's disease: benefits of dual cholinesterase inhibition. Eur Neurol 47 (2002) 64-70
    • (2002) Eur Neurol , vol.47 , pp. 64-70
    • Ballard, C.G.1
  • 17
    • 3042693940 scopus 로고    scopus 로고
    • Glutamate-mediated excitotoxicity and neurodegeneration in Alzheimer's disease
    • Hynd M.R., Scott H.L., and Dodd P.R. Glutamate-mediated excitotoxicity and neurodegeneration in Alzheimer's disease. Neurochem Int 45 (2004) 583-595
    • (2004) Neurochem Int , vol.45 , pp. 583-595
    • Hynd, M.R.1    Scott, H.L.2    Dodd, P.R.3
  • 18
    • 3042725543 scopus 로고    scopus 로고
    • NMDA receptor antagonists. A new therapeutic approach for Alzheimer's disease
    • Farlow M.R. NMDA receptor antagonists. A new therapeutic approach for Alzheimer's disease. Geriatrics 59 (2004) 22-27
    • (2004) Geriatrics , vol.59 , pp. 22-27
    • Farlow, M.R.1
  • 19
    • 0031902795 scopus 로고    scopus 로고
    • A randomized trial evaluating the efficacy and safety of ENA 713 (rivastigmine tartrate), a new acetylcholinesterase inhibitor, in patients with mild to moderately severe Alzheimer's disease
    • Corey-Bloom J., Anand R., and Veach J. A randomized trial evaluating the efficacy and safety of ENA 713 (rivastigmine tartrate), a new acetylcholinesterase inhibitor, in patients with mild to moderately severe Alzheimer's disease. Int J Psychopharmacol 2 (1998) 55-65
    • (1998) Int J Psychopharmacol , vol.2 , pp. 55-65
    • Corey-Bloom, J.1    Anand, R.2    Veach, J.3
  • 20
    • 0033528436 scopus 로고    scopus 로고
    • Efficacy and safety of rivastigmine in patients with Alzheimer's disease: international randomised controlled trial
    • Rosler M., Anand R., Cicin-Sain A., et al. Efficacy and safety of rivastigmine in patients with Alzheimer's disease: international randomised controlled trial. BMJ 318 (1999) 633-638
    • (1999) BMJ , vol.318 , pp. 633-638
    • Rosler, M.1    Anand, R.2    Cicin-Sain, A.3
  • 22
    • 0034627263 scopus 로고    scopus 로고
    • Efficacy and safety of galantamine in patients with mild to moderate Alzheimer's disease: multicentre randomised controlled trial
    • Wilcock G.K., Lilienfeld S., and Gaens E. Efficacy and safety of galantamine in patients with mild to moderate Alzheimer's disease: multicentre randomised controlled trial. BMJ 321 (2000) 1-7
    • (2000) BMJ , vol.321 , pp. 1-7
    • Wilcock, G.K.1    Lilienfeld, S.2    Gaens, E.3
  • 23
    • 0031883716 scopus 로고    scopus 로고
    • A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Alzheimer's disease
    • Rogers S.L., Farlow M.R., Doody R.S., Mohs R., and Friedhoff L.T. A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Alzheimer's disease. Neurology 50 (1998) 136-145
    • (1998) Neurology , vol.50 , pp. 136-145
    • Rogers, S.L.1    Farlow, M.R.2    Doody, R.S.3    Mohs, R.4    Friedhoff, L.T.5
  • 24
    • 0032926540 scopus 로고    scopus 로고
    • The effects of donepezil in Alzheimer's disease-results from a multinational trial
    • Burns A., Rossor M., Hecker J., et al. The effects of donepezil in Alzheimer's disease-results from a multinational trial. Dement Geriatr Cogn Disord 10 (1999) 237-244
    • (1999) Dement Geriatr Cogn Disord , vol.10 , pp. 237-244
    • Burns, A.1    Rossor, M.2    Hecker, J.3
  • 25
    • 0035859851 scopus 로고    scopus 로고
    • A 1-year, placebo-controlled preservation of function survival study of donepezil in AD patients
    • Mohs R.C., Doody R.S., Morris J.C., et al. A 1-year, placebo-controlled preservation of function survival study of donepezil in AD patients. Neurology 57 (2001) 481-488
    • (2001) Neurology , vol.57 , pp. 481-488
    • Mohs, R.C.1    Doody, R.S.2    Morris, J.C.3
  • 26
    • 0035859879 scopus 로고    scopus 로고
    • A 1-year, randomized, placebo-controlled study of donepezil in patients with mild to moderate AD
    • Winblad B., Engedal K., Soininen H., et al. A 1-year, randomized, placebo-controlled study of donepezil in patients with mild to moderate AD. Neurology 57 (2001) 489-495
    • (2001) Neurology , vol.57 , pp. 489-495
    • Winblad, B.1    Engedal, K.2    Soininen, H.3
  • 27
    • 1542283790 scopus 로고    scopus 로고
    • Reduction of behavioral disturbances and caregiver distress by galantamine in patients with Alzheimer's disease
    • Cummings J.L., Schneider L., Tariot P.N., Kershaw P.R., and Yuan W. Reduction of behavioral disturbances and caregiver distress by galantamine in patients with Alzheimer's disease. Am J Psychiatry 161 (2004) 532-538
    • (2004) Am J Psychiatry , vol.161 , pp. 532-538
    • Cummings, J.L.1    Schneider, L.2    Tariot, P.N.3    Kershaw, P.R.4    Yuan, W.5
  • 28
    • 0035964226 scopus 로고    scopus 로고
    • A 24-week, randomized, double-blind study of donepezil in moderate to severe Alzheimer's disease
    • Feldman H., Gauthier S., Hecker J., Vellas B., Subbiah P., and Whalen E. A 24-week, randomized, double-blind study of donepezil in moderate to severe Alzheimer's disease. Neurology 57 (2001) 613-620
    • (2001) Neurology , vol.57 , pp. 613-620
    • Feldman, H.1    Gauthier, S.2    Hecker, J.3    Vellas, B.4    Subbiah, P.5    Whalen, E.6
  • 30
    • 0442277838 scopus 로고    scopus 로고
    • Impact of rivastigmine on costs and on time spent in caregiving for families of patients with Alzheimer's disease
    • Marin D., Amaya K., Casciano R., et al. Impact of rivastigmine on costs and on time spent in caregiving for families of patients with Alzheimer's disease. Int Psychogeriatr 15 (2003) 385-398
    • (2003) Int Psychogeriatr , vol.15 , pp. 385-398
    • Marin, D.1    Amaya, K.2    Casciano, R.3
  • 31
    • 4344675352 scopus 로고    scopus 로고
    • Impact of donepezil treatment for Alzheimer's disease on caregiver time
    • Wimo A., Winblad B., Shah S.N., Chin W., Zhang R., and McRae T. Impact of donepezil treatment for Alzheimer's disease on caregiver time. Curr Med Res Opin 20 (2004) 1221-1225
    • (2004) Curr Med Res Opin , vol.20 , pp. 1221-1225
    • Wimo, A.1    Winblad, B.2    Shah, S.N.3    Chin, W.4    Zhang, R.5    McRae, T.6
  • 33
    • 0037707465 scopus 로고    scopus 로고
    • Donepezil is associated with delayed nursing home placement in patients with Alzheimer's disease
    • Geldmacher D.S., Provenzano G., McRae T., Mastey V., and Ieni J.R. Donepezil is associated with delayed nursing home placement in patients with Alzheimer's disease. J Am Geriatr Soc 51 (2003) 937-944
    • (2003) J Am Geriatr Soc , vol.51 , pp. 937-944
    • Geldmacher, D.S.1    Provenzano, G.2    McRae, T.3    Mastey, V.4    Ieni, J.R.5
  • 34
    • 0037211443 scopus 로고    scopus 로고
    • An economic evaluation of donepezil in mild to moderate Alzheimer's disease: results of a 1-year, double-blind, randomized trial
    • Wimo A., Winblad B., Engedal K., et al. An economic evaluation of donepezil in mild to moderate Alzheimer's disease: results of a 1-year, double-blind, randomized trial. Dement Geriatr Cogn Disord 15 (2003) 44-54
    • (2003) Dement Geriatr Cogn Disord , vol.15 , pp. 44-54
    • Wimo, A.1    Winblad, B.2    Engedal, K.3
  • 35
    • 0035991594 scopus 로고    scopus 로고
    • Efficacy and safety of rivastigmine in patients with Alzheimer's disease who failed to benefit from treatment with donepezil
    • Auriacombe S., Pere J.-J., Loria-Kanza Y., and Vellas B. Efficacy and safety of rivastigmine in patients with Alzheimer's disease who failed to benefit from treatment with donepezil. Curr Med Res Opin 18 (2002) 129-138
    • (2002) Curr Med Res Opin , vol.18 , pp. 129-138
    • Auriacombe, S.1    Pere, J.-J.2    Loria-Kanza, Y.3    Vellas, B.4
  • 37
    • 34247183650 scopus 로고    scopus 로고
    • Forest Laboratories. Namenda [package insert]. St. Louis, MO, 2003.
  • 38
    • 30344444750 scopus 로고    scopus 로고
    • A 24-week open-label extension study of memantine in moderate to severe Alzheimer disease
    • Reisberg B., Doody R., Stoffler A., Schmitt F., Ferris S., and Mobius H.J. A 24-week open-label extension study of memantine in moderate to severe Alzheimer disease. Arch Neurol 63 (2006) 49-54
    • (2006) Arch Neurol , vol.63 , pp. 49-54
    • Reisberg, B.1    Doody, R.2    Stoffler, A.3    Schmitt, F.4    Ferris, S.5    Mobius, H.J.6
  • 39
    • 0035661596 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled study of the efficacy and safety of donepezil in patients with Alzheimer's disease in the nursing home setting
    • Tariot P., Cummings J.L., Katz I.R., et al. A randomized, double-blind, placebo-controlled study of the efficacy and safety of donepezil in patients with Alzheimer's disease in the nursing home setting. J Am Geriatr Soc 49 (2001) 1590-1599
    • (2001) J Am Geriatr Soc , vol.49 , pp. 1590-1599
    • Tariot, P.1    Cummings, J.L.2    Katz, I.R.3
  • 40
    • 0038315311 scopus 로고    scopus 로고
    • Efficacy of donepezil on maintenance of activities of daily living in patients with moderate to severe Alzheimer's disease and the effect on caregiver burden
    • Feldman H., Gauthier S., Hecker J., et al. Efficacy of donepezil on maintenance of activities of daily living in patients with moderate to severe Alzheimer's disease and the effect on caregiver burden. J Am Geriatr Soc 51 (2003) 737-744
    • (2003) J Am Geriatr Soc , vol.51 , pp. 737-744
    • Feldman, H.1    Gauthier, S.2    Hecker, J.3
  • 41
    • 1642528058 scopus 로고    scopus 로고
    • Efficacy of rivastigmine in subjects with moderately severe Alzheimer's disease
    • Burns A., Spiegel R., and Quarg P. Efficacy of rivastigmine in subjects with moderately severe Alzheimer's disease. Int J Geriatr Psychiatry 19 (2004) 243-249
    • (2004) Int J Geriatr Psychiatry , vol.19 , pp. 243-249
    • Burns, A.1    Spiegel, R.2    Quarg, P.3
  • 42
    • 27844431640 scopus 로고    scopus 로고
    • Effects of rivastigmine treatment on the neuropsychiatric and behavioral disturbances of nursing home residents with moderate to severe probable Alzheimer's disease: a 26-week, multicenter, open-label study
    • Cummings J.L., Koumaras B., Chen M., and Mirski D. Effects of rivastigmine treatment on the neuropsychiatric and behavioral disturbances of nursing home residents with moderate to severe probable Alzheimer's disease: a 26-week, multicenter, open-label study. Am J Geriatr Pharmacother 3 (2005) 137-148
    • (2005) Am J Geriatr Pharmacother , vol.3 , pp. 137-148
    • Cummings, J.L.1    Koumaras, B.2    Chen, M.3    Mirski, D.4
  • 43
    • 0345872128 scopus 로고    scopus 로고
    • Memantine treatment in patients with moderate to severe Alzheimer disease already receiving donepezil: a randomized controlled trial
    • Tariot P.N., Farlow M.R., Grossberg G.T., Graham S.M., McDonald S., and Gergel I. Memantine treatment in patients with moderate to severe Alzheimer disease already receiving donepezil: a randomized controlled trial. JAMA 291 (2004) 317-324
    • (2004) JAMA , vol.291 , pp. 317-324
    • Tariot, P.N.1    Farlow, M.R.2    Grossberg, G.T.3    Graham, S.M.4    McDonald, S.5    Gergel, I.6
  • 44
    • 34247267131 scopus 로고    scopus 로고
    • Eisai Inc. Aricept [package insert]. Teaneck, NJ, 2000.
  • 45
    • 34247236150 scopus 로고    scopus 로고
    • Novartis Pharmaceuticals Corp. Exelon [package insert]. East Hanover, NJ, 2001.
  • 46
    • 34247206504 scopus 로고    scopus 로고
    • Ortho-McNeil Neurologics Inc. Razadyne [package insert]. Titusville, NJ, 2005.
  • 47
    • 34247280490 scopus 로고    scopus 로고
    • Ortho-McNeil Neurologics Inc. Razadyne ER [package insert]. Titusville, NJ, 2005.
  • 48
    • 0038240832 scopus 로고    scopus 로고
    • Drug interactions with cholinesterase inhibitors
    • Defilippi J.L., and Crismon M.L. Drug interactions with cholinesterase inhibitors. Drugs Aging 20 (2003) 437-444
    • (2003) Drugs Aging , vol.20 , pp. 437-444
    • Defilippi, J.L.1    Crismon, M.L.2
  • 49
    • 0034113018 scopus 로고    scopus 로고
    • Lack of adverse pharmacodynamic drug interactions with rivastigmine and twenty-two classes of medications
    • Grossberg G.T., Stahelin H.B., Messina J.C., Anand R., and Veach J. Lack of adverse pharmacodynamic drug interactions with rivastigmine and twenty-two classes of medications. Int J Geriatr Psychiatry 15 (2000) 242-247
    • (2000) Int J Geriatr Psychiatry , vol.15 , pp. 242-247
    • Grossberg, G.T.1    Stahelin, H.B.2    Messina, J.C.3    Anand, R.4    Veach, J.5
  • 50
    • 21544467552 scopus 로고    scopus 로고
    • Cholinesterase inhibitors for patients with Alzheimer's disease: systematic review of randomised clinical trials
    • Kaduszkiewicz H., Zimmermann T., Beck-Bornholdt H.P., and van den Bussche H. Cholinesterase inhibitors for patients with Alzheimer's disease: systematic review of randomised clinical trials. BMJ 331 (2005) 321-327
    • (2005) BMJ , vol.331 , pp. 321-327
    • Kaduszkiewicz, H.1    Zimmermann, T.2    Beck-Bornholdt, H.P.3    van den Bussche, H.4
  • 51
    • 20344381835 scopus 로고    scopus 로고
    • Vitamin E and donepezil for the treatment of mild cognitive impairment
    • Petersen R.C., Thomas R.G., Grundman M., et al. Vitamin E and donepezil for the treatment of mild cognitive impairment. N Engl J Med 352 (2005) 2379-2388
    • (2005) N Engl J Med , vol.352 , pp. 2379-2388
    • Petersen, R.C.1    Thomas, R.G.2    Grundman, M.3
  • 52
    • 4143052423 scopus 로고    scopus 로고
    • Efficacy of donepezil in mild cognitive impairment: a randomized placebo-controlled trial
    • Salloway S., Ferris S., Kluger A., et al. Efficacy of donepezil in mild cognitive impairment: a randomized placebo-controlled trial. Neurology 63 (2004) 651-657
    • (2004) Neurology , vol.63 , pp. 651-657
    • Salloway, S.1    Ferris, S.2    Kluger, A.3
  • 53
    • 33645510613 scopus 로고    scopus 로고
    • Galantamine for Alzheimer's disease and mild cognitive impairment
    • Loy C., and Schneider L. Galantamine for Alzheimer's disease and mild cognitive impairment. Cochrane Database Syst Rev (2006) CD001747
    • (2006) Cochrane Database Syst Rev
    • Loy, C.1    Schneider, L.2
  • 54
    • 34247209608 scopus 로고    scopus 로고
    • Press release: NICE consults on revised first draft guidance on the use of drugs to treat Alzheimer's disease (including a review of existing guidance no. 19). Available at: http://www.nice.org.uk/page.aspx?o=289014. Accessed June 8, 2006.
  • 55
    • 0242637070 scopus 로고    scopus 로고
    • Complementary and alternative medicines in the treatment of dementia: an evidence-based review
    • Diamond B., Johnson S., Torsney K., et al. Complementary and alternative medicines in the treatment of dementia: an evidence-based review. Drugs Aging 20 (2003) 981-998
    • (2003) Drugs Aging , vol.20 , pp. 981-998
    • Diamond, B.1    Johnson, S.2    Torsney, K.3
  • 58
    • 28244446721 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled trial of two doses of Ginkgo biloba extract in dementia of the Alzheimer's type
    • Schneider L.S., DeKosky S.T., Farlow M.R., Tariot P.N., Hoerr R., and Kieser M. A randomized, double-blind, placebo-controlled trial of two doses of Ginkgo biloba extract in dementia of the Alzheimer's type. Curr Alzheimer Res 2 (2005) 541-551
    • (2005) Curr Alzheimer Res , vol.2 , pp. 541-551
    • Schneider, L.S.1    DeKosky, S.T.2    Farlow, M.R.3    Tariot, P.N.4    Hoerr, R.5    Kieser, M.6
  • 59
    • 21844442389 scopus 로고    scopus 로고
    • Cytidinediphosphocholine (CDP-choline) for cognitive and behavioural disturbances associated with chronic cerebral disorders in the elderly
    • Fioravanti M., and Yanagi M. Cytidinediphosphocholine (CDP-choline) for cognitive and behavioural disturbances associated with chronic cerebral disorders in the elderly. Cochrane Database Syst Rev (2005) CD000269
    • (2005) Cochrane Database Syst Rev
    • Fioravanti, M.1    Yanagi, M.2
  • 60
    • 0030967165 scopus 로고    scopus 로고
    • A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study
    • Sano M., Ernesto C., Thomas R.G., et al. A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study. N Engl J Med 336 (1997) 1216-1222
    • (1997) N Engl J Med , vol.336 , pp. 1216-1222
    • Sano, M.1    Ernesto, C.2    Thomas, R.G.3
  • 61
    • 28544444991 scopus 로고    scopus 로고
    • Vitamin C and vitamin E for Alzheimer's disease
    • Boothby L.A., and Doering P.L. Vitamin C and vitamin E for Alzheimer's disease. Ann Pharmacother 39 (2005) 2073-2080
    • (2005) Ann Pharmacother , vol.39 , pp. 2073-2080
    • Boothby, L.A.1    Doering, P.L.2
  • 62
    • 33644499808 scopus 로고    scopus 로고
    • Estrogen-containing hormone therapy and Alzheimer's disease risk: understanding discrepant inferences from observational and experimental research
    • Henderson V.W. Estrogen-containing hormone therapy and Alzheimer's disease risk: understanding discrepant inferences from observational and experimental research. Neuroscience 138 (2006) 1031-1039
    • (2006) Neuroscience , vol.138 , pp. 1031-1039
    • Henderson, V.W.1
  • 63
    • 23044451174 scopus 로고    scopus 로고
    • Association between hormone replacement therapy and dementia: is it time to forget?
    • Almeida O.P., and Flicker L. Association between hormone replacement therapy and dementia: is it time to forget?. Int Psychogeriatr 17 (2005) 155-164
    • (2005) Int Psychogeriatr , vol.17 , pp. 155-164
    • Almeida, O.P.1    Flicker, L.2
  • 64
    • 0345830739 scopus 로고    scopus 로고
    • Rofecoxib: no effect on Alzheimer's disease in a 1-year, randomized, blinded, controlled study
    • Reines S.A., Block G.A., Morris J.C., et al. Rofecoxib: no effect on Alzheimer's disease in a 1-year, randomized, blinded, controlled study. Neurology 62 (2004) 66-71
    • (2004) Neurology , vol.62 , pp. 66-71
    • Reines, S.A.1    Block, G.A.2    Morris, J.C.3
  • 65
    • 21144447586 scopus 로고    scopus 로고
    • A randomized, double-blind, study of rofecoxib in patients with mild cognitive impairment
    • Thal L.J., Ferris S.H., Kirby L., et al. A randomized, double-blind, study of rofecoxib in patients with mild cognitive impairment. Neuropsychopharmacology 30 (2005) 1204-1215
    • (2005) Neuropsychopharmacology , vol.30 , pp. 1204-1215
    • Thal, L.J.1    Ferris, S.H.2    Kirby, L.3
  • 72
    • 0016823810 scopus 로고
    • ″Mini-mental state. A practical method for grading the cognitive state of patients for the clinician
    • Folstein M.F., Folstein S.E., and McHugh P.R. ″Mini-mental state. A practical method for grading the cognitive state of patients for the clinician. J Psychiatric Res 12 (1975) 189-198
    • (1975) J Psychiatric Res , vol.12 , pp. 189-198
    • Folstein, M.F.1    Folstein, S.E.2    McHugh, P.R.3
  • 73
    • 0014579432 scopus 로고
    • Assessment of older people: self-maintaining and instrumental activities of daily living
    • Lawton M.P., and Brody E.M. Assessment of older people: self-maintaining and instrumental activities of daily living. Gerontologist 9 (1969) 179-186
    • (1969) Gerontologist , vol.9 , pp. 179-186
    • Lawton, M.P.1    Brody, E.M.2
  • 74
    • 0027749448 scopus 로고
    • The consortium to establish a registry for Alzheimer's disease (CERAD). Part IV. Rates of cognitive change in the longitudinal assessment of probable Alzheimer's disease
    • Morris J.C., Edland S., Clark C., et al. The consortium to establish a registry for Alzheimer's disease (CERAD). Part IV. Rates of cognitive change in the longitudinal assessment of probable Alzheimer's disease. Neurology 43 (1993) 2457-2465
    • (1993) Neurology , vol.43 , pp. 2457-2465
    • Morris, J.C.1    Edland, S.2    Clark, C.3
  • 75
    • 0030862602 scopus 로고    scopus 로고
    • Validity and reliability of the Alzheimer's disease Cooperative Study-Clinical Global Impression of Change
    • Schneider L.S., Olin J.T., Doody R.S., et al. Validity and reliability of the Alzheimer's disease Cooperative Study-Clinical Global Impression of Change. Alzheimer Dis Assoc Disord 11 Suppl 2 (1997) S22-S32
    • (1997) Alzheimer Dis Assoc Disord , vol.11 , Issue.SUPPL. 2
    • Schneider, L.S.1    Olin, J.T.2    Doody, R.S.3
  • 77
    • 0034028609 scopus 로고    scopus 로고
    • Validation of the NPI-Q, a brief clinical form of the Neuropsychiatric Inventory
    • Kaufer D.I., Cummings J.L., Ketchel P., et al. Validation of the NPI-Q, a brief clinical form of the Neuropsychiatric Inventory. J Neuropsychiatry Clin Neurosci 12 (2000) 233-239
    • (2000) J Neuropsychiatry Clin Neurosci , vol.12 , pp. 233-239
    • Kaufer, D.I.1    Cummings, J.L.2    Ketchel, P.3
  • 78
    • 0345276668 scopus 로고    scopus 로고
    • Strategies for continued successful treatment of Alzheimer's disease: switching cholinesterase inhibitors
    • Gauthier S., Emre M., Farlow M.R., Bullock R., Grossberg G.T., and Potkin S.G. Strategies for continued successful treatment of Alzheimer's disease: switching cholinesterase inhibitors. Curr Med Res Opin 19 (2003) 707-714
    • (2003) Curr Med Res Opin , vol.19 , pp. 707-714
    • Gauthier, S.1    Emre, M.2    Farlow, M.R.3    Bullock, R.4    Grossberg, G.T.5    Potkin, S.G.6


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