메뉴 건너뛰기




Volumn 3, Issue 3, 2005, Pages 137-148

Effects of rivastigmine treatment on the neuropsychiatric and behavioral disturbances of nursing home residents with moderate to severe probable Alzheimer's disease: A 26-week, multicenter, open-label study

(16)  Cummings, Jeffrey L a   Koumaras, Barbara b   Chen, Michael b   Mirski, Dario b   Binder, Ellen c   Folstein, Marshal d   Zayas, Elsa M e   Ownby, Raymond f   Merideth, Charles H g   Scharre, Douglas W h   Tariot, Pierre i   Edwards, Keith j   Aupperle, Peter M k   Ellis, Jay M l   Pahl, Jorg J m   Kiev, Ari n  


Author keywords

Alzheimer's disease; Behavioral disturbances; Cognitive impairment; Dementia; Nursing home; Rivastigmine

Indexed keywords

RIVASTIGMINE;

EID: 27844431640     PISSN: 15435946     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1543-5946(05)80020-0     Document Type: Article
Times cited : (97)

References (49)
  • 1
    • 0036816758 scopus 로고    scopus 로고
    • Relative frequencies of Alzheimer disease, Lewy body, vascular and frontotemporal dementia, and hippocampal sclerosis in the State of Florida Brain Bank
    • Barker WW Luis CA Kashuba A et al. Relative frequencies of Alzheimer disease, Lewy body, vascular and frontotemporal dementia, and hippocampal sclerosis in the State of Florida Brain Bank Alzheimer Dis Assoc Disord 16 2002 203-212
    • (2002) Alzheimer Dis. Assoc. Disord. , vol.16 , pp. 203-212
    • Barker, W.W.1    Luis, C.A.2    Kashuba, A.3
  • 3
    • 0037174346 scopus 로고    scopus 로고
    • Prevalence of neuropsychiatric symptoms in dementia and mild cognitive impairment: Results from the cardiovascular health study
    • Lyketsos CG Lopez O Jones B et al. Prevalence of neuropsychiatric symptoms in dementia and mild cognitive impairment: Results from the cardiovascular health study JAMA 288 2002 1475-1483
    • (2002) JAMA , vol.288 , pp. 1475-1483
    • Lyketsos, C.G.1    Lopez, O.2    Jones, B.3
  • 4
    • 0034016372 scopus 로고    scopus 로고
    • Mental and behavioral disturbances in dementia: Findings from the Cache County Study on Memory in Aging
    • Lyketsos CG Steinberg M Tschanz JT et al. Mental and behavioral disturbances in dementia: Findings from the Cache County Study on Memory in Aging Am J Psychiatry 157 2000 708-714
    • (2000) Am. J. Psychiatry , vol.157 , pp. 708-714
    • Lyketsos, C.G.1    Steinberg, M.2    Tschanz, J.T.3
  • 5
  • 6
    • 0036816217 scopus 로고    scopus 로고
    • Impaired awareness, behavior disturbance, and caregiver burden in Alzheimer disease
    • Rymer S Salloway S Norton L et al. Impaired awareness, behavior disturbance, and caregiver burden in Alzheimer disease Alzheimer Dis Assoc Disord 16 2002 248-253
    • (2002) Alzheimer Dis. Assoc. Disord. , vol.16 , pp. 248-253
    • Rymer, S.1    Salloway, S.2    Norton, L.3
  • 7
    • 2342596564 scopus 로고    scopus 로고
    • Family caregiving of persons with dementia: Prevalence, health effects, and support strategies
    • Schulz R Martire LM Family caregiving of persons with dementia: Prevalence, health effects, and support strategies Am J Geriatr Psychiatry 12 2004 240-249
    • (2004) Am. J. Geriatr. Psychiatry , vol.12 , pp. 240-249
    • Schulz, R.1    Martire, L.M.2
  • 8
    • 14744288513 scopus 로고    scopus 로고
    • Caregiver psychological adjustment and institutionalization of persons with Alzheimer's disease
    • Gilley DW McCann JJ Bienias JL Evans DA Caregiver psychological adjustment and institutionalization of persons with Alzheimer's disease J Aging Health 17 2005 172-189
    • (2005) J. Aging Health , vol.17 , pp. 172-189
    • Gilley, D.W.1    McCann, J.J.2    Bienias, J.L.3    Evans, D.A.4
  • 9
    • 0037165667 scopus 로고    scopus 로고
    • Patient and caregiver characteristics and nursing home placement in patients with dementia
    • Yaffe K Fox P Newcomer R et al. Patient and caregiver characteristics and nursing home placement in patients with dementia JAMA 287 2002 2090-2097
    • (2002) JAMA , vol.287 , pp. 2090-2097
    • Yaffe, K.1    Fox, P.2    Newcomer, R.3
  • 10
    • 0035139773 scopus 로고    scopus 로고
    • Prevalence and pharmacological management of behavioural and psychological symptoms amongst dementia sufferers living in care environments
    • Margallo-Lana M Swann A O'Brien J et al. Prevalence and pharmacological management of behavioural and psychological symptoms amongst dementia sufferers living in care environments Int J Geriatr Psychiatry 16 2001 39-44
    • (2001) Int. J. Geriatr. Psychiatry , vol.16 , pp. 39-44
    • Margallo-Lana, M.1    Swann, A.2    O'Brien, J.3
  • 11
    • 0025404047 scopus 로고
    • The prevalence and management of dementia and other psychiatric disorders in nursing homes
    • Rovner BW German PS Broadhead J et al. The prevalence and management of dementia and other psychiatric disorders in nursing homes Int Psychogeriatr 2 1990 13-24
    • (1990) Int. Psychogeriatr. , vol.2 , pp. 13-24
    • Rovner, B.W.1    German, P.S.2    Broadhead, J.3
  • 12
    • 0035012352 scopus 로고    scopus 로고
    • Use of psychotropics in Sydney nursing homes: Associations with depression, psychosis, and behavioral disturbances
    • Draper B Brodaty H Low LF et al. Use of psychotropics in Sydney nursing homes: Associations with depression, psychosis, and behavioral disturbances Int Psychogeriatr 13 2001 107-120
    • (2001) Int. Psychogeriatr. , vol.13 , pp. 107-120
    • Draper, B.1    Brodaty, H.2    Low, L.F.3
  • 13
    • 0033625065 scopus 로고    scopus 로고
    • The relationship between donepezil and behavioral disturbances in patients with Alzheimer's disease
    • Cummings JL Donohue JA Brooks RL The relationship between donepezil and behavioral disturbances in patients with Alzheimer's disease Am J Geriatr Psychiatry 8 2000 134-140
    • (2000) Am. J. Geriatr. Psychiatry , vol.8 , pp. 134-140
    • Cummings, J.L.1    Donohue, J.A.2    Brooks, R.L.3
  • 14
    • 0029838038 scopus 로고    scopus 로고
    • Neuropsychiatric aspects of Alzheimer's disease: The cholinergic hypothesis revisited
    • Cummings JL Kaufer D Neuropsychiatric aspects of Alzheimer's disease: The cholinergic hypothesis revisited Neurology 47 1996 876-883
    • (1996) Neurology , vol.47 , pp. 876-883
    • Cummings, J.L.1    Kaufer, D.2
  • 15
    • 0345059945 scopus 로고    scopus 로고
    • Cholinesterase inhibitor therapies and neuropsychiatric manifestations of Alzheimer's disease
    • Wynn ZJ Cummings JL Cholinesterase inhibitor therapies and neuropsychiatric manifestations of Alzheimer's disease Dement Geriatr Cogn Disord 17 2004 100-108
    • (2004) Dement. Geriatr. Cogn. Disord. , vol.17 , pp. 100-108
    • Wynn, Z.J.1    Cummings, J.L.2
  • 16
    • 12844274439 scopus 로고    scopus 로고
    • Pharmacological treatment of neuropsychiatric symptoms of dementia: A review of the evidence
    • Sink KM Holden KF Yaffe K Pharmacological treatment of neuropsychiatric symptoms of dementia: A review of the evidence JAMA 293 2005 596-608
    • (2005) JAMA , vol.293 , pp. 596-608
    • Sink, K.M.1    Holden, K.F.2    Yaffe, K.3
  • 17
    • 3042567016 scopus 로고    scopus 로고
    • Long-term donepezil treatment in 565 patients with Alzheimer's disease (AD2000): Randomised double-blind trial
    • for the AD2000 Collaborative Group
    • Courtney C Farrell D Gray R et al. for the AD2000 Collaborative Group Long-term donepezil treatment in 565 patients with Alzheimer's disease (AD2000): Randomised double-blind trial Lancet 363 2004 2105-2115
    • (2004) Lancet , vol.363 , pp. 2105-2115
    • Courtney, C.1    Farrell, D.2    Gray, R.3
  • 18
    • 0035661596 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled study of the efficacy and safety of donepezil in patients with Alzheimer's disease in the nursing home setting
    • Tariot PN Cummings JL Katz IR et al. A randomized, double-blind, placebo-controlled study of the efficacy and safety of donepezil in patients with Alzheimer's disease in the nursing home setting J Am Geriatr Soc 49 2001 1590-1599
    • (2001) J. Am. Geriatr. Soc. , vol.49 , pp. 1590-1599
    • Tariot, P.N.1    Cummings, J.L.2    Katz, I.R.3
  • 19
    • 20244384575 scopus 로고    scopus 로고
    • Quetiapine and rivastigmine and cognitive decline in Alzheimer's disease: Randomised double blind placebo controlled trial
    • Ballard C Margallo-Lana M Juszczak E et al. Quetiapine and rivastigmine and cognitive decline in Alzheimer's disease: Randomised double blind placebo controlled trial BMJ 330 2005 874
    • (2005) BMJ , vol.330 , pp. 874
    • Ballard, C.1    Margallo-Lana, M.2    Juszczak, E.3
  • 20
    • 0027429837 scopus 로고
    • Brain selective inhibition of acetylcholinesterase: A novel approach to therapy for Alzheimer's disease
    • Enz A Amstutz R Boddeke H et al. Brain selective inhibition of acetylcholinesterase: A novel approach to therapy for Alzheimer's disease Prog Brain Res 98 1993 431-438
    • (1993) Prog. Brain Res. , vol.98 , pp. 431-438
    • Enz, A.1    Amstutz, R.2    Boddeke, H.3
  • 21
    • 0031902795 scopus 로고    scopus 로고
    • A randomized trial evaluating the efficacy and safety of ENA 713 (rivastigmine tartrate), a new acetylcholinesterase inhibitor, in patients with mild to moderately severe Alzheimer's disease
    • Corey-Bloom J Anand R Veach J A randomized trial evaluating the efficacy and safety of ENA 713 (rivastigmine tartrate), a new acetylcholinesterase inhibitor, in patients with mild to moderately severe Alzheimer's disease Int J Geriatr Psychopharmacol 1 1998 55-65
    • (1998) Int. J. Geriatr. Psychopharmacol. , vol.1 , pp. 55-65
    • Corey-Bloom, J.1    Anand, R.2    Veach, J.3
  • 22
    • 0033528436 scopus 로고    scopus 로고
    • Efficacy and safety of rivastigmine in patients with Alzheimer's disease: International randomised controlled trial
    • [published correction appears in BMJ. 2001;322:1456]
    • Rosler M Anand R Cicin-Sain A et al. Efficacy and safety of rivastigmine in patients with Alzheimer's disease: International randomised controlled trial [published correction appears in BMJ. 2001;322:1456] BMJ 318 1999 633-638
    • (1999) BMJ , vol.318 , pp. 633-638
    • Rosler, M.1    Anand, R.2    Cicin-Sain, A.3
  • 23
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
    • McKhann G Drachman D Folstein M et al. Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease Neurology 34 1984 939-944
    • (1984) Neurology , vol.34 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3
  • 24
    • 0004235298 scopus 로고
    • Fourth Edition Washington, DC: American Psychiatric Association
    • American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders Fourth Edition 1994 American Psychiatric Association Washington, DC
    • (1994) Diagnostic and Statistical Manual of Mental Disorders
  • 25
    • 0016823810 scopus 로고
    • "Mini-mental state." A practical method for grading the cognitive state of patients for the clinician
    • Folstein MF Folstein SE McHugh PR "Mini-mental state." A practical method for grading the cognitive state of patients for the clinician J Psychiatr Res 12 1975 189-198
    • (1975) J. Psychiatr. Res. , vol.12 , pp. 189-198
    • Folstein, M.F.1    Folstein, S.E.2    McHugh, P.R.3
  • 26
    • 0018887732 scopus 로고
    • Pathological verification of ischemic score in differentiation of dementias
    • Rosen WG Terry RD Fuld PA et al. Pathological verification of ischemic score in differentiation of dementias Ann Neurol 7 1980 486-488
    • (1980) Ann. Neurol. , vol.7 , pp. 486-488
    • Rosen, W.G.1    Terry, R.D.2    Fuld, P.A.3
  • 27
    • 0033989218 scopus 로고    scopus 로고
    • The use of the neuropsychiatric inventory in nursing home residents. Characterization and measurement
    • Wood S Cummings JL Hsu MA et al. The use of the neuropsychiatric inventory in nursing home residents. Characterization and measurement Am J Geriatr Psychiatry 8 2000 75-83
    • (2000) Am. J. Geriatr. Psychiatry , vol.8 , pp. 75-83
    • Wood, S.1    Cummings, J.L.2    Hsu, M.A.3
  • 29
    • 0030862602 scopus 로고    scopus 로고
    • Validity and reliability of the Alzheimer's Disease Cooperative Study-Clinical Global Impression of Change. The Alzheimer's Disease Cooperative Study
    • Schneider LS Olin JT Doody RS et al. Validity and reliability of the Alzheimer's Disease Cooperative Study-Clinical Global Impression of Change. The Alzheimer's Disease Cooperative Study Alzheimer Dis Assoc Disord 11 Suppl 2 1997 22-32
    • (1997) Alzheimer Dis. Assoc. Disord. , vol.11 , Issue.SUPPL. 2 , pp. 22-32
    • Schneider, L.S.1    Olin, J.T.2    Doody, R.S.3
  • 30
    • 0027238944 scopus 로고
    • Physostigmine ameliorates the delusions of Alzheimer's disease
    • Cummings JL Gorman DG Shapira J Physostigmine ameliorates the delusions of Alzheimer's disease Biol Psychiatry 33 1993 536-541
    • (1993) Biol. Psychiatry , vol.33 , pp. 536-541
    • Cummings, J.L.1    Gorman, D.G.2    Shapira, J.3
  • 31
    • 0029914548 scopus 로고    scopus 로고
    • Effect of tacrine on behavioral symptoms in Alzheimer's disease: An open-label study
    • Kaufer DI Cummings JL Christine D Effect of tacrine on behavioral symptoms in Alzheimer's disease: An open-label study J Geriatr Psychiatry Neurol 9 1996 1-6
    • (1996) J. Geriatr. Psychiatry Neurol. , vol.9 , pp. 1-6
    • Kaufer, D.I.1    Cummings, J.L.2    Christine, D.3
  • 32
    • 0031842293 scopus 로고    scopus 로고
    • Metrifonate benefits cognitive, behavioral, and global function in patients with Alzheimer's disease
    • Morris JC Cyrus PA Orazem J et al. Metrifonate benefits cognitive, behavioral, and global function in patients with Alzheimer's disease Neurology 50 1998 1222-1230
    • (1998) Neurology , vol.50 , pp. 1222-1230
    • Morris, J.C.1    Cyrus, P.A.2    Orazem, J.3
  • 33
    • 0033060809 scopus 로고    scopus 로고
    • The effects of metrifonate on the cognitive, behavioral, and functional performance of Alzheimer's disease patients
    • Raskind MA Cyrus PA Ruzicka BB Gulanski BI for the Metrifonate Study Group The effects of metrifonate on the cognitive, behavioral, and functional performance of Alzheimer's disease patients J Clin Psychiatry 60 1999 318-325
    • (1999) J. Clin. Psychiatry , vol.60 , pp. 318-325
    • Raskind, M.A.1    Cyrus, P.A.2    Ruzicka, B.B.3    Gulanski, B.I.4
  • 34
    • 0030851210 scopus 로고    scopus 로고
    • Effect of tacrine on language, praxis, and noncognitive behavioral problems in Alzheimer disease
    • Raskind MA Sadowsky CH Sigmund WR et al. Effect of tacrine on language, praxis, and noncognitive behavioral problems in Alzheimer disease Arch Neurol 54 1997 836-840
    • (1997) Arch. Neurol. , vol.54 , pp. 836-840
    • Raskind, M.A.1    Sadowsky, C.H.2    Sigmund, W.R.3
  • 35
    • 0034720864 scopus 로고    scopus 로고
    • A 5-month, randomized, placebo-controlled trial of galantamine in AD
    • for the Galantamine USA-10 Study Group
    • Tariot PN Solomon PR Morris JC et al. for the Galantamine USA-10 Study Group A 5-month, randomized, placebo-controlled trial of galantamine in AD Neurology 54 2000 2269-2276
    • (2000) Neurology , vol.54 , pp. 2269-2276
    • Tariot, P.N.1    Solomon, P.R.2    Morris, J.C.3
  • 36
    • 0030902127 scopus 로고    scopus 로고
    • Effects of xanomeline, a selective muscarinic receptor agonist, on cognitive function and behavioral symptoms in Alzheimer disease
    • Bodick NC Offen WW Levey AI et al. Effects of xanomeline, a selective muscarinic receptor agonist, on cognitive function and behavioral symptoms in Alzheimer disease Arch Neurol 54 1997 465-473
    • (1997) Arch. Neurol. , vol.54 , pp. 465-473
    • Bodick, N.C.1    Offen, W.W.2    Levey, A.I.3
  • 37
    • 0032928421 scopus 로고    scopus 로고
    • Neuropsychiatric symptoms and cholinergic therapy for Alzheimer's disease
    • Levy ML Cummings JL Kahn-Rose R Neuropsychiatric symptoms and cholinergic therapy for Alzheimer's disease Gerontology 45 Suppl 1 1999 15-22
    • (1999) Gerontology , vol.45 , Issue.SUPPL. 1 , pp. 15-22
    • Levy, M.L.1    Cummings, J.L.2    Kahn-Rose, R.3
  • 38
    • 0036363671 scopus 로고    scopus 로고
    • Advances in the treatment of Alzheimer's disease: Benefits of dual cholinesterase inhibition
    • Ballard CG Advances in the treatment of Alzheimer's disease: Benefits of dual cholinesterase inhibition Eur Neurol 47 2002 64-70
    • (2002) Eur. Neurol. , vol.47 , pp. 64-70
    • Ballard, C.G.1
  • 39
    • 0002031187 scopus 로고    scopus 로고
    • Neuroanatomy of cholinesterases in the normal human brain and in Alzheimer's disease
    • Giacobini E ed. Martin Dunitz London
    • Mesulam M Neuroanatomy of cholinesterases in the normal human brain and in Alzheimer's disease In Giacobini E ed. Cholinesterase and Cholinesterase Inhibitors 2000 Martin Dunitz London 121-137
    • (2000) Cholinesterase and Cholinesterase Inhibitors , pp. 121-137
    • Mesulam, M.1
  • 40
    • 0027337833 scopus 로고
    • Neurological cholinesterases in the normal brain and in Alzheimer's disease: Relationship to plaques, tangles, and patterns of selective vulnerability
    • Wright CI Geula C Mesulam MM Neurological cholinesterases in the normal brain and in Alzheimer's disease: Relationship to plaques, tangles, and patterns of selective vulnerability Ann Neurol 34 1993 373-384
    • (1993) Ann. Neurol. , vol.34 , pp. 373-384
    • Wright, C.I.1    Geula, C.2    Mesulam, M.M.3
  • 41
    • 0029766994 scopus 로고    scopus 로고
    • Efficacy and safety results of the early phase studies with Exelon® (ENA-713) in Alzheimer's disease: An overview
    • Anand R Gharabawi M Enz A Efficacy and safety results of the early phase studies with Exelon® (ENA-713) in Alzheimer's disease: An overview J Drug Dev Clin Pract 8 1996 109-116
    • (1996) J. Drug Dev. Clin. Pract. , vol.8 , pp. 109-116
    • Anand, R.1    Gharabawi, M.2    Enz, A.3
  • 42
    • 0022616905 scopus 로고
    • Distribution of the molecular forms of acetylcholinesterase in human brain: Alterations in dementia of the Alzheimer type
    • Fishman EB Siek GC MacCallum RD et al. Distribution of the molecular forms of acetylcholinesterase in human brain: Alterations in dementia of the Alzheimer type Ann Neurol 19 1986 246-252
    • (1986) Ann. Neurol. , vol.19 , pp. 246-252
    • Fishman, E.B.1    Siek, G.C.2    MacCallum, R.D.3
  • 43
    • 0025213932 scopus 로고
    • Molecular forms of acetylcholinesterase in subcortical areas of normal and Alzheimer disease brain
    • Siek GC Katz LS Fishman EB et al. Molecular forms of acetylcholinesterase in subcortical areas of normal and Alzheimer disease brain Biol Psychiatry 27 1990 573-580
    • (1990) Biol. Psychiatry , vol.27 , pp. 573-580
    • Siek, G.C.1    Katz, L.S.2    Fishman, E.B.3
  • 44
    • 0001142454 scopus 로고    scopus 로고
    • The effect of cholinesterase inhibitors studies with brain imaging
    • Giacobini E ed. Martin Dunitz London
    • Nordberg A The effect of cholinesterase inhibitors studies with brain imaging In Giacobini E ed. Cholinesterase and Cholinesterase Inhibitors 2000 Martin Dunitz London 237-247
    • (2000) Cholinesterase and Cholinesterase Inhibitors , pp. 237-247
    • Nordberg, A.1
  • 45
    • 0035699431 scopus 로고    scopus 로고
    • Brain metabolic and clinical effects of rivastigmine in Alzheimer's disease
    • Potkin SG Anand R Fleming K et al. Brain metabolic and clinical effects of rivastigmine in Alzheimer's disease Int J Neuropsychopharmacol 4 2001 223-230
    • (2001) Int. J. Neuropsychopharmacol. , vol.4 , pp. 223-230
    • Potkin, S.G.1    Anand, R.2    Fleming, K.3
  • 46
    • 0034676757 scopus 로고    scopus 로고
    • Efficacy of rivastigmine in dementia with Lewy bodies: A randomised, double-blind, placebo-controlled international study
    • McKeith I Del Ser T Spano P et al. Efficacy of rivastigmine in dementia with Lewy bodies: A randomised, double-blind, placebo-controlled international study Lancet 356 2000 2031-2036
    • (2000) Lancet , vol.356 , pp. 2031-2036
    • McKeith, I.1    Del Ser, T.2    Spano, P.3
  • 47
    • 0035526287 scopus 로고    scopus 로고
    • Rivastigmine in the treatment of parkinsonian psychosis and cognitive impairment: Preliminary findings from an open trial
    • Reading PJ Luce AK McKeith IG Rivastigmine in the treatment of parkinsonian psychosis and cognitive impairment: Preliminary findings from an open trial Mov Disord 16 2001 1171-1174
    • (2001) Mov. Disord. , vol.16 , pp. 1171-1174
    • Reading, P.J.1    Luce, A.K.2    McKeith, I.G.3
  • 48
    • 10044283107 scopus 로고    scopus 로고
    • Rivastigmine for dementia associated with Parkinson's disease
    • Emre M Aarsland D Albanese A et al. Rivastigmine for dementia associated with Parkinson's disease N Engl J Med 351 2004 2509-2518
    • (2004) N. Engl. J. Med. , vol.351 , pp. 2509-2518
    • Emre, M.1    Aarsland, D.2    Albanese, A.3
  • 49
    • 0023928930 scopus 로고
    • Alzheimer's disease. A psychiatrist's perspective
    • Billig N Alzheimer's disease. A psychiatrist's perspective Nurs Clin North Am 23 1988 125-133
    • (1988) Nurs. Clin. North Am. , vol.23 , pp. 125-133
    • Billig, N.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.