Examination of acylated 4-aminopiperidine-4-carboxylic acid residues in the phosphotyrosyl+1 position of Grb2 SH2 domain-binding tripeptides

Journal of Medicinal Chemistry

Volumn 50, Issue 8, 2007, Pages 1978-1982

  Kang, Sang Uk ^a   Won, Jun Choi ^a   Oishi, Shinya ^a   Lee, Kyeong ^a   Karki, Rajeshri G ^a   Worthy, Karen M ^b   Bindu, Lakshman K ^b   Nicklaus, Marc C ^a   Fisher, Robert J ^b   Burke Jr , Terrence R ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b SAIC FREDERICK INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; CARBAMIC ACID DERIVATIVE; CARBOXYLIC ACID DERIVATIVE; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; PHOSPHORUS DERIVATIVE; PIPERIDINE DERIVATIVE; PROTEIN SH2; TRIPEPTIDE DERIVATIVE; TYROSINE DERIVATIVE;

ACYLATION; ARTICLE; BETA SHEET; BINDING AFFINITY; DISSOCIATION; DRUG CONFORMATION; DRUG PROTEIN BINDING; HYDROGEN BOND; PROTEIN DOMAIN; SURFACE PLASMON RESONANCE;

ACYLATION; BINDING SITES; GRB2 ADAPTOR PROTEIN; MODELS, MOLECULAR; MOLECULAR CONFORMATION; OLIGOPEPTIDES; PHOSPHOTYROSINE; PIPERIDINES; SRC HOMOLOGY DOMAINS;

EID: 34247229736     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0614073     Document Type: Article

References (16)

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