Small peptides containing phosphotyrosine and adjacent αMe- phosphotyrosine or its mimetics as highly potent inhibitors of Grb2 SH2 domain

Journal of Medicinal Chemistry

Volumn 42, Issue 18, 1999, Pages 3737-3741

  Liu, Wang Qing ^a   Vidal, Michel ^a   Gresh, Nohad ^a   Roques, Bernard P ^a   Garbay, Christiane ^a  

^a Laboratoire de Pharmacochimie   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; ALPHA METHYLPHOSPHOTYROSINE DERIVATIVE; PHOSPHOTYROSINE; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; HYDROPHILICITY; HYDROPHOBICITY; MOLECULAR MODEL; PEPTIDE ANALYSIS; PEPTIDE SYNTHESIS; PROTEIN PROTEIN INTERACTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; BINDING SITES; GRB2 ADAPTOR PROTEIN; MODELS, MOLECULAR; PEPTIDES; PHOSPHOTYROSINE; PROTEIN BINDING; PROTEINS; SRC HOMOLOGY DOMAINS;

EID: 0033539113     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9911074     Document Type: Article

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