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Volumn 8, Issue 15, 2006, Pages 3299-3301

Synthetic studies on Et-743. Asymmetric, stereocontrolled construction of the tetrahydroisoquinoline core via radical cyclization on a glyoxalimine

Author keywords

[No Author keywords available]

Indexed keywords

1,3 DIOXOLANE DERIVATIVE; IMINE; TETRAHYDROISOQUINOLINE DERIVATIVE; TRABECTEDIN;

EID: 33746911128     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol061192r     Document Type: Article
Times cited : (30)

References (35)
  • 18
    • 0035948184 scopus 로고    scopus 로고
    • For reviews of radical reactions involving imines and related compounds, see: (a) Friestad, G. K. Tetrahedron 2001, 57, 5461-5496.
    • (2001) Tetrahedron , vol.57 , pp. 5461-5496
    • Friestad, G.K.1
  • 26
    • 0003161893 scopus 로고
    • (R)-Garner's aldehyde was synthesized from D-serine according to: Garner, P.; Park, J. M. Org. Synth. 1992, 70, 18-28.
    • (1992) Org. Synth. , vol.70 , pp. 18-28
    • Garner, P.1    Park, J.M.2
  • 30
    • 33746898059 scopus 로고    scopus 로고
    • note
    • Working with 2.5 mmol of 11. The reaction has been performed on 0.125-2.5 mmol (50 mg-1 g) of 11 and consistently provides 3 with isolated yields of 58-61%.
  • 31
    • 33746895665 scopus 로고    scopus 로고
    • note
    • Details of the X-ray crystal structure determination are to be published elsewhere.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.