N-(4-hydroxyphenyl)retinamide increases ceramide and is cytotoxic to acute lymphoblastic leukemia cell lines, but not to non-malignant lymphocytes

Leukemia

Volumn 16, Issue 5, 2002, Pages 902-910

  O'Donnell, P H ^a   Guo, W X ^a   Reynolds, C P ^a,b   Maurer, B J ^a,b  

^a CHILDREN S HOSPITAL LOS ANGELES   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

1 O acylceramide; 4 HPR; Acute lymphoblastic leukemia; Ceramide; Glucosylceramide; PPMP

Indexed keywords

ANTILEUKEMIC AGENT; CERAMIDE; FENRETINIDE; PROPANOL;

ACUTE LYMPHOBLASTIC LEUKEMIA; ACYLATION; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL KILLING; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG CYTOTOXICITY; DRUG EXPOSURE; GLYCOSYLATION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; LYMPHOBLASTOID CELL LINE; MONONUCLEAR CELL; NULL CELL; PHOSPHOLIPID SYNTHESIS; PRE B LYMPHOCYTE; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 0036100132     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2402485     Document Type: Article

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